by

Dr . Vikas Saroch

Mrutyunjay Rasa

To elaborate pharmaceutical process

To understand pharmaco kinetics and

dynamics

To understand probable mode of action

To understand Pharmacopoeial standards

To compare with different varieties of

Mrutyunjay rasa

OBJECTIVES

Widely used in Jwara

Easy to prepare

Explained in most of the classical texts

More than 10 types

With different ingredients , indications and method of

preparation

Majority of ingredients contains Parada and Gandhaka

Pharma companies taken reference from Bhaisajya

Ratnavali.

AFI and PSAF also explained the same

Introduction

Bhaisajya Ratnavali Jvarachikista

2 types explained

5th chapter 510-519

5th chapter 758-759

In Bharat Bhaisajya Ratnakar about 10

different formulation explained under the

name of Mrutyunjay rasa .

Different References

Visa (Aconitum ferox wall) Rt . Tr 1 Part

(Gomutra Shodhita)

Marica (Piper nigrum linn) Fr. 1 Part

Pippali (Piper longum) Fr. 1 Part

S. Gandhaka - 1 Part

S.Tankana - 1 Part

Hingula shodhita( Jambira Swarasa) - 2

Parts

Or Parada 1 Part

Bhaishajya Ratnavali Jvarachikista 5th chapter Sh.No. 510-519

Shudh Parada 1 Part Shudh Gandhaka 2 Parts Shudh Tankana 3 Part Shudh Vatsanabh 8 Part Dhatura Beeja Churna 16

PartTrikatu Churna 32 Part

Acc. To Bhaishajya Ratnavali Jwarachikista 758-759

Grahya Swaroopa:

Shooka pitchaNavaneeta SamaprabhaKhatina, Snigda (Ay.P.

2/20) Properties: Katu, Tikta, Kashya RasaUsna ViryaDeepana,Pachana,

Agnikari, Rasayana, Amanashaka.

Gandhak

Properties :

Katu rasaUsna ViryaRuksha ,Tikshna

GunaBalya, Agnivardhaka, Anti-dot for

Vatsnanabha.

Tankan

HingulaSweta rekhaHamsa padaPravalabha (red)Properties:Tikta, Katu, KashayaUsna ViryaDeepana, Agnivardaka,

Rasayana, Sarvadoshagna, Ruchya

Grahya Lakshana

Vatsanabh (Aconitum ferox)

Properties :Usna ,

Jwaraghana,Balya

Indication :Jwara, Kasa,

Shwasa, Vatroga,Grahani

Dose : 1/16 – 1/8 ratti

Properties :Pachaka

Agnideepaka,Ruchikar Swedakar

Contains piperin which helps in reducing fever specially in malaria .

Marich (Piper nigrum Linn)

Properties :Rasayan ,Deepana, Paachana,Usna

Indication :Agnimandya ,Kasa,

Swasa,Jeernajwara

Pippali (Piper longum)

Shudh Gandhak, Shudh Vatsanabh, Marich Churna, ShudhTankan, Pippali Churn, Shudh Hingula or Parada

Mixed together to form a fine blend

Mixture is processed with Aradrak/Jambira Swaras

Till a uniform blend is achieved

Mrutyunjay Rasa

PREPARATION

Visa (Aconitum ferox wall) Rt . Tr 1 Part (Gomutra Shodhita)

Marica (Piper nigrum linn) Fr. 1 Part

Pippali (Piper longum) Fr. 1 Part

S. Gandhaka - 1 Part

S.Tankana - 1 Part

Hingula shodhita (jambira Swarasa) - 2Part

Or rasa (Parada) – Shudha 1 Part

Mrtyunjaya Rasa (BR,Jvaradhikara;409-411) AFI 20:30

Dose : 125mg

Anupana : Mastu, Ardraka Swarasa, Honey

Important therapeutic use: Sarva Jvara,Visama Jvara, Jirna Jvara

   Ingredients

Parad ,Gandhak, Hingula ,Tankan, Vatsanabh, Marich, Pipali, Jambiri Nimbu Swaras.

Therapatic uses: Indicated in general debility of children, effective in fever & sannipat Jwara. Indigestion

Dosage: 1 tab. with madhu. twice a day.

Baidyanath (Bhaisajya Ratnavali)

Visa, Maricha, Pippali, Gandhaka, Tankan , Hingula, Rasa

Indication : JwaraDose : 125mg Anupana : Mastu , Ardraka SwarasaManufacture : Baidyanath, Dabur,

Dhanwantri, Dindyal, UMA , Gurukal Kangri , UAP , Zandu

Packing : 40 tab Price : 20-25 Rs

Organoleptic characters • Colour - Brick Red • Smell - Faint • Touch - Medium • Taste - Astringent

Tablet Hardness Test Tablet Disintegration Test

Analytical Findings / Quality Test

Free sulpher Not less than 13.2 % w/w Not more than 14.9 % w/wSulphur Not less than 17.9 % w/w

Not more than 19.3 % w/wMercury Not less than 24.3 % w/w

Not more than 29.7 % w/wIron Not more than 1.265 % w/wSodium Not more than 18.12 % w/wSulphate Not more than 3.53 % w/w

Quantative estimation

Chloride Not more than 1.0 % w/wMagnesium Not more than 1.0 % w/wPhosphate Not more than 3.66 % w/wSilica Not more than 1.03 % w/w

(Acid insoluble material)Ash value Not less than 12.4 % w/w

Not more than 19.0 % w/w

Acid insoluble ash Not less than 0.66 % w/w

Not more than 1.90 % w/w

Dose - 100 to 250mg

Popularly used drug in various fevers.Easily prepared using easily available

ingredients.Shows rapid action.Widely available with a number of

manufacturers producing it.Most of the companies use reference from

Bhaishajya Ratnavali.

Summary

Bhaishajya Ratnavali

Bharat Bhaishajya Ratnakar

Rasa Ratan Samuchaya

Rasa Raja Sundra

Rasa Chandashu

Ayurveda Prakesha

Yoga Ratanakar

AFI

PSAF

www.nlam.in

References

Thank u…..