2005

Pyrimidine derivativesR 0510 Nickel Mediated Biginelli-Like Three Component Coupling Reaction:

A Solvent-Free Microwave Assisted Synthesis of Spiro-Fused Heterocycles. — A three-component coupling reaction between barbituric or Meldrum's acid (I), benzal-dehyde (II) and urea (III) using nickel or cobalt chloride hexahydrate as Lewis acid is described. — (SAINI, A.; KUMAR, S.; SANDHU*, J. S.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 43 (2004) 11, 2482-2484; Dep. Chem., Punjabi Univ., Patiala 147 002, India; Eng.) — H. Haber

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