normal blood values
DESCRIPTION
NORMAL BLOOD VALUES. NORMAL HEMATOLOGICAL VALUES. SHEIKHA. 10 trillion “10 13 ” new blood cells must be replaced Each day to maintain steady state blood counts! This is equivalent to an annual number of cells approximating the total body weight, but the total - PowerPoint PPT PresentationTRANSCRIPT
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NORMALBLOOD VALUES
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SHEIKHA
NORMAL
HEMATOLOGICAL
VALUES
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10 trillion “1013” new blood cells must be replaced Each day to maintain steady state blood counts!
This is equivalent to an annual number of cells approximating the total body weight, but the totalbone marrow of an adult human contains around1012 cells, 10 fold less than the daily need!
Marrow contains 1 stem cell per 20 million nucleated cells
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Normal Normal
ValuesValues
MEN WOMENCORD
CHILD 3 m
RCC+/- 0.5X1012/L
5.0 4.3 5.0 4.0
HbHbgm/dLgm/dL
13.0 13.0 toto
17.017.0
12.0 12.0
toto
15.015.0
13.5 13.5 toto
19.519.5
9.59.5
toto
13.513.5
Hct.Hct.
(PCV)(PCV)
40%40%
toto
54%54%
36%36%
toto
46%46%
44%44%
toto
64%64%
32%32%
toto
44%44%
MCV (fL)MCV (fL) 76-76-9696
76-9676-96 106106 9696
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The Sheikhas
1818 cubic meters
1800 kilos
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Normal ValuesNormal Values
= ------------ = ------------ == ------------ = ------------ =
= ------------ = -------- = 90 fL= ------------ = -------- = 90 fL
Mean Cell VolumeMean Cell Volume
MCV
PCV
RCC
0.45 L
5.0 x 1012
0.45 x 1015 fL
5.0 x 1012
450
5.0
NORMAL MCV = 76 – 96 fL
SHEIKHA
0.45L
5X
1012
1 L
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Normal Normal ValuesValues
= ------------ = ------------ == ------------ = ------------ =
= ----------- = ------------ = 30 pg = ----------- = ------------ = 30 pg
Mean Cell Mean Cell HemoglobinHemoglobin
MCH
Hb
RCC
15 gm/dL
5.0 x 1012/L
5.0 x 1012/L
150 gm/L 150 x 1012 pg
5.0 x 1012/L
NORMAL MCH = 27 – 32 pg
SHEIKHA
15gm/dL
5 trillion
1 Liter
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Normal ValuesNormal Values
= ------------ = ------------ == ------------ = ------------ =
= 333 g/L = 33 g/dL= 333 g/L = 33 g/dL
Mean Cell VolumeMean Cell Volume
MCHC
Hb
PCV
150 g/L
0.45 L/L
NORMAL MCHC IN ADULTS & CHILDREN = 32 – 36 g/dL
SHEIKHA
0.45150gm
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RETICULOCYTE COUNTRETICULOCYTE COUNT
0.2 to 2.0%
=10,000 to 100,000/uL (Adults & Children)
2.0 to 6.0%Mean = 150,000
(Infants/ Cord Blood)
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BLOOD VOLUMEBLOOD VOLUME
60 to 80 ml/Kg60 to 80 ml/Kg
PLASMA
PCV
55%
45%
40 to 50 ml/Kg
Men: 25 to 35 ml/KgWomen: 20 to 30 ml/Kg
SHEIKHA
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Differential White Cell CountsDifferential White Cell Counts
Total WBC: Total WBC: 4.0 to 11.0 X 104.0 to 11.0 X 109 9 / L/ L
4,000 to 11,000 / uL4,000 to 11,000 / uL
<100
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
2,000to
7,500/uL1,500
to4,000/uL
200to
800
40to
440
SHEIKHA
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BLOOD CELLS LIFE SPANBLOOD CELLS LIFE SPAN
10 days
120days T1/2
7 hours
RBCWBC
Platelet
SHEIKHA
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Iron statusIron status
Serum Iron UIBC
TIBC
13 – 32 umol /L
100 ug /L
45 – 70 umol /L
300 ug /L
Male: 30-300 ug/L Female: 15-200
FERRITIN
SHEIKHA
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CBCCBC
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NormalNormal
M: 13-17 M: 13-17 F: 12-15F: 12-15
M: M: 40-54%40-54% F: F: 36-46%36-46%
+/- 0.5+/- 0.5 M: M: 5X105X101212/L/L F: F: 4.3X104.3X101212//LL
76-9676-96
27-3227-32
32-3632-36
0.2-2.00.2-2.0
11.5-14.511.5-14.5
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
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NormalNormal
4,000 – 11,000/uL4,000 – 11,000/uL2,000 – 7,500/ uL2,000 – 7,500/ uL
1,500 – 4,000/1,500 – 4,000/ uL uL200 – 800/ uL200 – 800/ uL
40 – 440/ uL40 – 440/ uL
<100/ uL<100/ uL
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
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NormalNormal
150,000 – 150,000 – 400,000/uL400,000/uL
5.0 - 8.0 fL5.0 - 8.0 fL
0.1 - 0.4 %0.1 - 0.4 %
PlateletsPlatelets
MPVMPVPlateletcriPlateletcritt
PDWPDW
Platelet in Platelet in smearsmear
200 X 109/L X 5 fL= 1000 X 109 fL of platelets/L of blood =1.0 X 1012 fL/L = 1 ml of platelets/L of blood =
0.1%
400 X 109/L X 8 fL= 3200 X 109 fL of platelets/L of blood = 3.2 X 1012 fL/L = 3.2 ml of platelets/L of blood =
0.3%
Total Platelet Mass in an adult ~ 5 to 20 mls
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
Platelets
MPVPlateletcrit
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
Platelets
MPVPlateletcrit
CASES
CLINICAL AND LAB.DATA
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Case 1HAYASA50 years
Patient: Back Pain Smear: Rouleaux Marrow: 80% PCs ESR: 110 mm/hr
?Dx:
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic.
RDWRDW
12.012.0
0.350.35
4.04.0
8888
3030
3434
22%%
1515%%
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
4.44.4
60%60%
30%30%
8%8%
2%2%
Platelets
MPVPlateletcrit
200,000
66
Case 1HAYASA50 years
Patient: Back Pain Smear: Rouleaux Marrow: 80% PCs ESR: 110 mm/hr
?Dx:
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.0
0.350.35
4.04.0
8888
3030
3434
22
1515
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
4.44.4
60%60%
30%30%
8%8%
2%2%
Platelets
MPVPlateletcrit
200,000
66
Case 1HAYASA50 years
Patient: Back Pain Smear: Rouleaux Marrow: 80% PCs ESR: 110 mm/hr
?Dx:
MULTIPLE MYELOMA
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.280.28
4.04.0
7070
2020
2828
1111
1717
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
11.011.0
55%55%
35%35%
5%5%
3%3%
2%2%
Platelets
MPVPlateletcrit
8,008,0000
10100.0080.008
%%
CASE 2
ALI HADI3 years
BruisesEpistaxisHematuria
Mild splenomegaly
Marrow full of Megakaryocytes
Smear: Few Giant platelets
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.0
0.280.28
4.04.0
7070
2020
2828
1111
1717
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
11.011.0
55%55%
35%35%
5%5%
3%3%
2%2%
Platelets
MPVPlateletcrit
8,008,0000
10100.0080.008
%%
CASE 2
ALI HADI3 years
BruisesEpistaxisHematuria
Mild splenomegaly
Marrow full of Megakaryocytes
Smear: Few Giant platelets
I T P
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
4.04.00.120.12
1.251.25
9696
3232
3333
0%0%
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8.08.0
60%60%
30%30%
08%08%
02%02%
Platelets
MPVPlateletcrit
200,00200,0000
770.14%0.14%
Case 3
Abu Bakr30 years
IndianSevere pallorGiven 3 units of RBC
Marrow devoid of RBC precursors
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
4.04.00.120.12
1.251.25
9696
3232
3333
0%0%
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8.08.0
60%60%
30%30%
08%08%
02%02%
Platelets
MPVPlateletcrit
200,00200,0000
770.14%0.14%
Case 3
Abu Bakr30 years
IndianSevere pallorGiven 3 units of RBC
Marrow devoid of RBC precursors PRCA
Pure Red Cell Aplasia
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.0
0.350.35
4.34.3
8080
2525
3131
2%2%
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
166166
40%40%
6%6%
1%1%
5%5%
3%3%
2%2%
3%3%
25%25%
5%5%
10%10%Platelets
MPVPlateletcrit
400,00400,0000
770.28%0.28%
Case 4
Sultan48 years
Loss of weightModerate splenomegalyMild hepatomegaly
Positive Philadelphia chromosome
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.0
0.350.35
4.34.3
8080
2525
3131
2%2%
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
166166
40%40%
6%6%
1%1%
5%5%
3%3%
2%2%
3%3%
25%25%
5%5%
10%10%Platelets
MPVPlateletcrit
400,00400,0000
770.28%0.28%
Case 4
Sultan48 years
Loss of weightModerate splenomegalyMild hepatomegaly
Positive Philadelphia chromosome CML
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
15.015.0
0.450.45
5.05.0
9090
3030
3333
1.5%1.5%
1212
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
4646
50%50%
10%10%
4%4%
4%4%
2%2%
2%2%
4%4%
8%8%
16%16%Platelets
MPVPlateletcrit
200200
12120.12%0.12%
Case 5Yahia
20 years
Hyperpyrexia
Streptococcal tonsillitis
High NAP score
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
15.015.0
0.450.45
5.05.0
9090
3030
3333
1.5%1.5%
1212
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
4646
50%50%
10%10%
4%4%
4%4%
2%2%
2%2%
4%4%
8%8%
16%16%Platelets
MPVPlateletcrit
200200
12120.12%0.12%
Case 5Yahia
20 years
Hyperpyrexia
Streptococcal tonsillitis
High NAP score
LEUKEMOID REACTION
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.0
0.220.22
2.82.8
7878
2828
3535
22
12.012.0
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2828
5%5%
15%15%
80%80%
Platelets
MPVPlateletcrit
20,0020,0000
550.01%0.01%
Case 6FAHAD
8 YEARS
FeverChest InfectionGum BleedingPallor
Blood smear & marrow are full of PAS +ve blasts
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.0
0.220.22
2.82.8
7878
2828
3535
22
12.012.0
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2828
5%5%
15%15%
80%80%
Platelets
MPVPlateletcrit
20,0020,0000
550.01%0.01%
Case 6FAHAD
8 YEARS
FeverChest InfectionGum BleedingPallor
Blood smear & marrow are full of PAS +ve blasts ALL
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.280.28
2.92.9
9797
2727
2929
22
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2.02.0
40%40%
20%20%
4%4%
5%5%
1%1%
5%5%
5%5%
5%5%
5%5%
10%10%Platelets
MPVPlateletcrit
100,00100,0000
66
0.060.06
Case 7Abdul Rahman
16 Years
Anemia not responding to RHypogranular neutrophilsHypercellular marrow12% Marrow Blasts
![Page 34: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/34.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.280.28
2.92.9
9797
2727
2929
22
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2.02.0
40%40%
20%20%
4%4%
5%5%
1%1%
5%5%
5%5%
5%5%
5%5%
10%10%Platelets
MPVPlateletcrit
100,00100,0000
66
0.060.06
Case 7Abdul Rahman
16 Years
Anemia not responding to RHypogranular neutrophilsHypercellular marrow12% Marrow Blasts
RAEB
![Page 35: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/35.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
6.06.00.360.36
6.06.0
6060
1010
1717
66
1818
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
nRBCnRBC
6060
30%30%
20%20%
5%5%
5%5%
40%40%
Platelets
MPVPlateletcrit
300,00300,0000
880.24%0.24%
Case 8SHADI8 Years
Hypochromic microcytic red cellsTarget cellsMarked increase of nRBCHbF= 100%Splenectomized
![Page 36: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/36.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
6.06.00.360.36
6.06.0
6060
1010
1717
66
1818
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
nRBCnRBC
6060
30%30%
20%20%
5%5%
5%5%
40%40%
Platelets
MPVPlateletcrit
300,00300,0000
880.24%0.24%
Case 8SHADI8 Years
Hypochromic microcytic red cellsTarget cellsMarked increase of nRBCHbF= 100%Splenectomized
β- THALASSEMIA MAJOR
![Page 37: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/37.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
6.06.00.220.22
2.02.0
110110
3030
2727
4%4%
1717
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2828
8%8%
10%10%
2%2%
2%2%
2%2%
60%60%
4%4%
4%4%
4%4%
4%4%Platelets
MPVPlateletcrit
3030
11110.030.03
Case 9SAUD NAIF60 Years
Perianal abscess
Marrow: Hypercellular; Abnormal pronormoblasts & myeloblasts forming majority of the cells
![Page 38: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/38.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
6.06.00.220.22
2.02.0
110110
3030
2727
4%4%
1717
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2828
8%8%
10%10%
2%2%
2%2%
2%2%
60%60%
4%4%
4%4%
4%4%
4%4%Platelets
MPVPlateletcrit
3030
11110.030.03
Case 9SAUD NAIF60 Years
Perianal abscess
Marrow: Hypercellular; Abnormal pronormoblasts & myeloblasts forming majority of the cells
Erythroleukemia
(AML M6)
![Page 39: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/39.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
10.010.00.260.26
5.25.2
5050
1919
3838
1212
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1010
70%70%
25%25%
5%5%
Platelets
MPVPlateletcrit
280,00280,0000
66
0.170.17
Case 10MAHA RUSHDI
17 Years
Mild Pallor & Jaundice
Positive Family history
Smear: Small & hyper- chromic red cells
High MCHC
+ Osmotic Fragility Test
Moderate splenomegaly
![Page 40: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/40.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
10.010.00.260.26
5.25.2
5050
1919
3838
1212
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1010
70%70%
25%25%
5%5%
Platelets
MPVPlateletcrit
280,00280,0000
66
0.170.17
Case 10MAHA RUSHDI
17 Years
Mild Pallor & Jaundice
Positive Family history
Smear: Small & hyper- chromic red cells
High MCHC
+ Osmotic Fragility Test
Moderate splenomegaly
HEREDITARY
SPHEROCYTOSIS
![Page 41: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/41.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
9.09.00.300.30
3.23.2
9595
2828
3030
1010
1616
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
3737
46%46%
6%6%
20%20%
4%4%
4%4%
4%4%
4%4%
4%4%
4%4%
4%4%Platelets
MPVPlateletcrit
400,00400,0000
88
0.320.32
Case 11SAED AL-NAMI
70 Years
Massive splenomegalyNegative Ph’ ChromosomeMarrow: Hypercellular with agranular & hypogranular neutrophils
![Page 42: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/42.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
9.09.00.300.30
3.23.2
9595
2828
3030
1010
1616
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
3737
46%46%
6%6%
20%20%
4%4%
4%4%
4%4%
4%4%
4%4%
4%4%
4%4%Platelets
MPVPlateletcrit
400,00400,0000
88
0.320.32
Case 11SAED AL-NAMI
70 Years
Massive splenomegalyNegative Ph’ ChromosomeMarrow: Hypercellular with agranular & hypogranular neutrophils
CMML
![Page 43: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/43.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.300.30
4.34.3
7070
1919
2727
55
1616
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1111
7070
2525
44
11
Platelets
MPVPlateletcrit
280,00280,0000
66
0.170.17
Case 12HUDA RDENY
20 Years
Severe back painSplenic atrophyHb-electrophoresis is pendingTargets & sickle cells
![Page 44: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/44.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.300.30
4.34.3
7070
1919
2727
55
1616
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1111
7070
2525
44
11
Platelets
MPVPlateletcrit
280,00280,0000
66
0.170.17
Case 12HUDA RDENY
20 Years
Severe back painSplenic atrophyHb-electrophoresis is pendingTargets & sickle cells
Hb SS
![Page 45: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/45.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.0
0.350.35
4.14.1
8585
2929
3434
44
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
7676
30%30%
4%4%
2%2%
2%2%
2%2%
18%18%
4%4%
28%28%
5%5%
5%5%Platelets
MPVPlateletcrit
380,00380,0000
88
0.3%0.3%
Case 13ABDU ABDU
24 Years
Massive splenomegaly+ Ph’ ChromosomeStarted on Hydrea
![Page 46: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/46.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.0
0.350.35
4.14.1
8585
2929
3434
44
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
7676
30%30%
4%4%
2%2%
2%2%
2%2%
18%18%
4%4%
28%28%
5%5%
5%5%Platelets
MPVPlateletcrit
380,00380,0000
88
0.3%0.3%
Case 13ABDU ABDU
24 Years
Massive splenomegaly+ Ph’ ChromosomeStarted on Hydrea
CML
“Accelerated Phase”
![Page 47: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/47.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.00.350.35
4.14.1
8585
2929
3434
22
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1212
82%82%
8%8%
6%6%
4%4%
2%2%
Platelets
MPVPlateletcrit
300,00300,0000
77
0.210.21
Case 14Al-Hifzi
18 Years
HemarthrosisNormal P.T.Prolonged APTTNormal Bleeding TimeHIV Positive
![Page 48: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/48.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.0
0.350.35
4.14.1
8585
2929
3434
22
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1212
82%82%
8%8%
6%6%
4%4%
2%2%
Platelets
MPVPlateletcrit
300,00300,0000
77
0.210.21
Case 14Al-Hifzi
18 Years
HemarthrosisNormal P.T.Prolonged APTTNormal Bleeding TimeHIV Positive
HEMOPHILIA A
![Page 49: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/49.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
6.06.00.180.18
2.22.2
8282
2727
3333
1818
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2.22.2
40%40%
50%50%
8%8%
2%2%
Platelets
MPVPlateletcrit
40,0040,0000
990.04%0.04%
Case 15AISHA
17 Years
Huge SpleenFever
Marrow was requested to exclude an intracellular parasitic disease
![Page 50: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/50.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
6.06.00.180.18
2.22.2
8282
2727
3333
1818
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2.22.2
40%40%
50%50%
8%8%
2%2%
Platelets
MPVPlateletcrit
40,0040,0000
990.04%0.04%
Case 15AISHA
17 Years
Huge SpleenFever
Marrow was requested to exclude an intracellular parasitic disease Kala Azar
“Visceral Leishmaniasis”
![Page 51: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/51.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.00.350.35
4.34.3
8181
2626
3131
22
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1010
50%50%
40%40%
8%8%
2%2%
Platelets
MPVPlateletcrit
140,00140,0000
880.11%0.11%
Case 16FATMA
48 Years
Six months history ofcervical lymphadenopathy (biopsy pending)ESR 80 mm/hrHepatosplenomegalyMarrow: normal
![Page 52: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/52.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.00.350.35
4.34.3
8181
2626
3131
22
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1010
50%50%
40%40%
8%8%
2%2%
Platelets
MPVPlateletcrit
140,00140,0000
880.11%0.11%
Case 16FATMA
48 Years
Six months history ofcervical lymphadenopathy (biopsy pending)ESR 80 mm/hrHepatosplenomegalyMarrow: normal
? Lymphoma
![Page 53: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/53.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.00.350.35
4.34.3
8181
2626
3131
22
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
160160
3%3%
95%95%
1%1%
1%1%
Platelets
MPVPlateletcrit
140.00140.0000
cervical lymphadenopathyESR 80 mm/hrHepatosplenomegalyMarrow: 80% mature lymphocytes
Case 17ABDULLAH68 Years
![Page 54: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/54.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.00.350.35
4.34.3
8181
2626
3131
22
1313
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
160160
3%3%
95%95%
1%1%
1%1%
Platelets
MPVPlateletcrit
140.00140.0000
cervical lymphadenopathyESR 80 mm/hrHepatosplenomegalyMarrow: 80% mature lymphocytes
CLL
Case 17ABDULLA
H68 Years
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Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
21.021.0
0.640.64
7.27.2
8888
2929
3333
44
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2121
50%50%
20%20%
5%5%
5%5%
2%2%
1%1%
1%1%
2%2%
6%6%
8%8%Platelets
MPVPlateletcrit
800,00800,0000
1010
0.8%0.8%
Case 18ZHARA
60 Years
PlethoricHeadacheRetinal vein thrombosisHot bath induced pruritisProlonged Bleeding Time
![Page 56: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/56.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
21.021.0
0.640.64
7.27.2
8888
2929
3333
44
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
2121
50%50%
20%20%
5%5%
5%5%
2%2%
1%1%
1%1%
2%2%
6%6%
8%8%Platelets
MPVPlateletcrit
800,00800,0000
1010
0.8%0.8%
Case 18ZHARA
60 Years
PlethoricHeadacheRetinal vein thrombosisHot bath induced pruritisProlonged Bleeding Time
PRV
![Page 57: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/57.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.260.26
3.23.2
8181
2525
3131
1414
1616
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1111
60%60%
35%35%
4%4%
1%1%
Platelets
MPVPlateletcrit
350,00350,0000
880.28%0.28%
Case 19Bel Gasim
6 Years
Mild JaundiceDark Urine
Rapid drop of HbMarked polychromasiaNegative Coomb’sReceived malaria prophylaxis before a family trip to red sea
Heinz Bodies
![Page 58: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/58.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.260.26
3.23.2
8181
2525
3131
1414
1616
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1111
60%60%
35%35%
4%4%
1%1%
Platelets
MPVPlateletcrit
350,00350,0000
880.28%0.28%
Case 19Bel Gasim
6 Years
Mild JaundiceDark Urine
Rapid drop of HbMarked polychromasiaNegative Coomb’sReceived malaria prophylaxis before a family trip to red sea
G6PDH Deficiency
![Page 59: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/59.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
4.04.00.120.12
1.251.25
9696
3232
3333
00
1515
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1111
50%50%
45%45%
5%5%
Platelets
MPVPlateletcrit
8,0008,000
660.000.0055
Case 20AYED
14 Years
FeverPallorBleedingAcellular marrow
![Page 60: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/60.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
4.04.00.120.12
1.251.25
9696
3232
3333
00
1515
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1111
50%50%
45%45%
5%5%
Platelets
MPVPlateletcrit
8,0008,000
660.000.0055
Case 20AYED
14 Years
FeverPallorBleedingAcellular marrow
APLASTIC ANEMIA
![Page 61: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/61.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.230.23
2.92.9
8080
2828
3434
0.20.2
1212
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8.08.0
68%68%
30%30%
10%10%
2%2%
Platelets
MPVPlateletcrit
320,00320,0000
770.22%0.22%
Case 21OMAR
28 Years
Rheumatoid arthritisESR 85 mm/hrLow Serum iron & TIBCNo response to iron
![Page 62: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/62.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.08.00.230.23
2.92.9
8080
2828
3434
0.20.2
1212
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8.08.0
68%68%
30%30%
10%10%
2%2%
Platelets
MPVPlateletcrit
320,00320,0000
770.22%0.22%
Case 21OMAR
28 Years
Rheumatoid arthritisESR 85 mm/hrLow Serum iron & TIBCNo response to iron
ACD
“Anemia of Chronic Disorders”
![Page 63: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/63.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.58.50.280.28
2.92.9
9898
3030
3030
11
1212
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8080
2%2%
5%5%
13%13%
80%80%
Platelets
MPVPlateletcrit
20,0020,0000
550.01%0.01%
Case 22KHALID
30 Years
FeverPallorLymphadenopathyGum hypertrophyMarrow & Blood are full of Blasts positive for non-specific esterase
![Page 64: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/64.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
8.58.50.280.28
2.92.9
9898
3030
3030
11
1212
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8080
2%2%
5%5%
13%13%
80%80%
Platelets
MPVPlateletcrit
20,0020,0000
550.01%0.01%
Case 22KHALID
30 Years
FeverPallorLymphadenopathyGum hypertrophyMarrow & Blood are full of Blasts positive for non-specific esterase
AML
“M5”
![Page 65: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/65.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.00.400.40
4.54.5
8989
2727
3030
22
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1010
55%55%
40%40%
5%5%
Platelets
MPVPlateletcrit
180,00180,0000
770.12%0.12%
Case 23MOH’D5 Years
Black SaudiMaxillary Bone swellingNormal marrow & smear
Lesion biopsy: starry-skyLymphoproliferativedisease
![Page 66: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/66.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
12.012.00.400.40
4.54.5
8989
2727
3030
22
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
1010
55%55%
40%40%
5%5%
Platelets
MPVPlateletcrit
180,00180,0000
770.12%0.12%
Case 23MOH’D5 Years
Black SaudiMaxillary Bone swellingNormal marrow & smear
Lesion biopsy: starry-skyLymphoproliferativedisease
Burkitt’s
Lymphoma
![Page 67: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/67.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.00.340.34
3.83.8
9090
2929
3232
1.21.2
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8.08.0
60%60%
35%35%
5%5%
Platelets
MPVPlateletcrit
150,00150,0000
77
0.1%0.1%
Case 24JOAN
60 Years
HeadacheBlurred vision
Marrow: Full of Lymphocytes, LPC & Plasma CellsSmear: RouleauxIgM = 10 gm/L
No osteolytic lesionsR/ EPO
![Page 68: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/68.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
11.011.00.340.34
3.83.8
9090
2929
3232
1.21.2
1414
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
8.08.0
60%60%
35%35%
5%5%
Platelets
MPVPlateletcrit
150,00150,0000
77
0.1%0.1%
Case 24JOAN
60 Years
HeadacheBlurred vision
Marrow: Full of Lymphocytes, LPC & Plasma CellsSmear: RouleauxIgM = 10 gm/L
No osteolytic lesionsR/ EPO Waldenstrom’s
Macroglobulinemia
![Page 69: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/69.jpg)
THANK YOU
![Page 70: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/70.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
Platelets
MPVPlateletcrit
![Page 71: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/71.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
Platelets
MPVPlateletcrit
![Page 72: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/72.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
Platelets
MPVPlateletcrit
![Page 73: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/73.jpg)
Hb. Hb. g/dLg/dL
Hct.Hct.
RCCRCC
MCV MCV fLfL
MCH MCH pgpg
MCHC MCHC g/dLg/dL
Retic. Retic. %%
RDW %RDW %
WBCWBCNeutrophilsNeutrophils
LymphocyteLymphocytess
MonocytesMonocytes
EosinophilsEosinophils
BasophilsBasophils
Blasts:Blasts:
PromyelocytePromyelocytes:s:
Myelocytes:Myelocytes:
MetamyelocyteMetamyelocytes:s:
Band or Band or Stab:Stab:
Platelets
MPVPlateletcrit
![Page 74: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/74.jpg)
Flow CytometryFlow Cytometry
![Page 75: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/75.jpg)
![Page 76: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/76.jpg)
![Page 77: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/77.jpg)
![Page 78: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/78.jpg)
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![Page 80: NORMAL BLOOD VALUES](https://reader036.vdocuments.net/reader036/viewer/2022081417/568145d4550346895db2d7b5/html5/thumbnails/80.jpg)