penyakit kulit alergi
TRANSCRIPT
Penyakit Kulit Alergi
Allergic Reactions
• Immune system naturally responds to foreign substances in body
• Allergic reaction: exaggerated response to foreign substance
• Allergen: substance causing exaggerated effect
Classification of Immunologic Reactions (Gel and Coombs)
Hypersensitivity Reactions
Atopy
• Atopy is the term for the genetic trait to have a predisposition for localized anaphylaxis.
• Atopic individuals have higher levels of IgE and eosinophils.
Urticaria
Wheal and flare pale centers surrounded by rings of
erythemamore uniformly pink in color Itching resolve completely within 24 hours
Urticaria
Mast cell degranulation physical factors Medications Infections Foods
Urticaria
Treatment Eliminating non-sedating anti-histamines sedating anti-histamines Corticosteroid
Signs and Symptoms: Hives
Urticaria - dermatographism
Type 1 – prick tests immediate
Atopic dermatitis
a chronic, relapsing skin disorder that often begins in childhood, improves with age, but often manifests itself in adulthood with a relapsing course.
Atopic dermatitis
Acute lesion: pruritic, erythematous macules or papules
excoriated papules with crust and serum exudates
Diagnosis
Atopic dermatitis
Treatment relief of pruritus restoration of the barrier function of skin elimination of environmental factors that
exacerbate AD amelioration of the inflammation
Food Hypersensitivity
Contact Dermatitis
• eczematous rash site of contact• any site affected, hands and face • allergic; type IV cell-mediated hypersensitivity reaction
following sensitisation eg; cosmetics, nickel,