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Page 1: Periscope: Midwifery · 164 INSTRUMENTAL TREATMENT OF UTERINE DISEASES.[AUG. The right Fallopian tube was enormously dilated, and connected by old ad- hesions to the uterus and rectum

1854.] INSTRUMENTAL TREATMENT OF UTERINE DISEASES. 163

MIDWIFERY.

REPORT OF M. DEPAUL ON THE TREATMENT OF DISPLACEMENTS OF THE UTERUS BY

INTRA-UTERINE PESSARIES, AND DISCUSSION AT THE ACADEMIE 1MPERIALE DE

MEDECINE OF PARIS.

This subject, which has lately created an extraordinary sensation in the Academy of Medicine, was first brought before them by Dr Broca, who detailed a case from his own practice, where death had occurred after the use of the Uterine Catheter. M. Cruveilhier followed up the statement by the relation of another fatal case, and expressed himself as strongly opposed to the use of uterine instruments. A committee, composed of MM. Robert, Huguier, and

Depaul, was appointed ; and their report, drawn up by M. Depaul, after enter- ing at great length into the whole subject of uterine displacements, has con- demned in most severe and decided terms, the use of the intra-uterine pessaries and bougies. The following is a condensed account of the cases, the report, and of the discussion which followed it.

CASES OF MM. BROCA AND CRUVEILHIER.

Broca s Case.?A woman, set. 39, who had borne three children, the youngest ten years ago, was admitted to the Hopital de Lourcine, October 4tli, 1853. She was thin, and wasted (fletrie), but her general health was tolerably good, and she stated that she had never had any serious disease. About a year before admission, from which period she dates her illness, the menses became suppressed, and never returned ; at the same time pains in the thighs, disorder of the digestion, habitual and obstinate constipation, and frequent calls to make water came on. She stated that she had got much thinner, and suffered much. On examination, very marked antiversion was detected ; the cervix was enlarged and granular, and a considerable quantity of glairy and puru- lent matter was discharged from the os. On the 7th October the uterine sound was introduced, it reached to G^ centimetres. The uterus was easily brought to the normal direction, and kept there for five minutes ; the patient com-

plaining of no pain. On the 8th and 10th the same manoeuvre was repeated, and the patient declared herself much relieved. On the 11th, slight pain was felt on the introduction of the instrument, and the patient complained of the hypogastrium when the uterus was replaced in position ; the sound was left in for two or three minutes. The pain became much more intense on the 12th, and was followed soon after by fever, nausea, bilious vomiting, and constipa- tion ; leeches and cataplasms were applied, and on the loth the fever had ceased and the patient seemed better ; but the vomiting continued, and inter- mittent pains came on frequently in the abdomen, apparently spreading from the uterus. On the following days the attacks of pain were more frequent, the vomiting became incessant, the pulse small, and the abdomen tympanitic, and the patient died on the 23d, after a long and painful struggle. Autopsy, twenty-four hours after death. Skull not opened. Thoracic organs healthy. In the abdomen, old and strong adhesions of the right extremity of the trans- verse colon, and of the great omentum to the abdominal parietes; the stomach, duodenum, and jejunum were greatly distended to about GO centimetres above the ilio-coecal valve. At this point the intestine was adherent to the uterus, and became suddenly contracted (retreci); above, it measured 1G centimetres in cir- cumference, below, it was reduced to the size of the index finger. The whole of the large intestine, as far as the descending colon, was strongly retracted (fortement revenu sur lui-meme) and empty; beyond this point the calibre was diminished, but not to the same degree. Below the adhesion, the intestine was discoloured but

healthy; above it, as far as the duodenum, which was sound, there were evident traces of congestion and inflammation. Independently of these old adhesions, there were recent ones formed by a greyish gelatinous juice, semitransparent, and not yet organised ; in short, there were the evidences of two attacks of

peritonitis, one of old standing, the other recent.

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164 INSTRUMENTAL TREATMENT OF UTERINE DISEASES. [AUG.

The right Fallopian tube was enormously dilated, and connected by old ad- hesions to the uterus and rectum ; no trace of the right ovary could be found. The cavity of the Fallopian tube contained a considerable quantity of chocolate coloured pus. At the angle of the uterus, near the insertion of the right Fallopian tube, was found a small collection of pus very near the peritoneal surface." M. Broca supposes that the introduction of the sound caused first metritis,

and subsequently peritonitis, and that the recent being added to the old ad- hesions, had completed the intestinal obstruction. On the other hand M. Yalleix contends, that the obstruction pre-existed before the sound was in-

troduced, and was quite independent of it. The pathological appearances are certainly described in a confused manner in M. Broca's report ; at one part it is stated " that there was no fluid in the peritoneum, and no recent false

membrane, and that, with the exception of the old adhesions, the peritoneum might be called healthy." And at the end of the description we are told of the exudations of recent lymph (des adherences formees par an sue gelati- neux grisdtre, demistranparent, non encore organise), showing recent peri- tonitis.

Cruveilhier's Case.?A young woman, set. 24, married for four years, and extremely distressed at having no children, was found to have a slight ante- version of the uterus, to which her barrenness was ascribed. The introduc- tion of the uterine sound having occasioned great pain, she removed to Paris and put herself under the care of M. Yalleix. During a residence of a month there, the sound was introduced five times, but could never be retained beyond a few hours, on account of the sickness, distension of the abdomen, and severe pain (angoisses), which required the withdrawal of the instrument. Her health became so much affected, that her mother insisted on giving up the treatment and returning home. On her arrival there, the family physician recognised the symptoms of metro-peritonitis, in an aggravated form. Her condition be-

coming worse, M. Cruveilhier was sent for ; he found the anteversion still

persistent; an extreme degree of marasmus; the symptoms of peritonitis, espe- cially the pain of abdomen, had somewhat abated, but the uterus was extremely tender. The pulse was filiform and numbered 120 in the minute. The chest was examined ; some mucous rales existed at the apex of the right lung, but there were no signs of tubercles. A week after the patient died. The exami- nation of the body was not allowed. M. Yalleix is of opinion that the patient was tubercular, and had probably

sunk under tubercular peritonitis. m. depaul's report.

In commencing his report, M. Depaul undertakes to prove,?1st, That uterine affections, usually attributed to displacement, have an entirely different origin. 2d, That in most of the alleged cases, another more frequent pathological condition, which produces uterine symptoms and even sometimes causes dis- placement, has been overlooked. 3d, That science possesses a simple and rational treatment for displacements, as efficacious, or more so, than intra- uterine pessaries. 4th, That the facts adduced in favour of the treatment by these instruments, only show their entire inefficiency; and 5th, That we must take into serious consideration the numerous facts which prove that the most formidable affections and even death itself, may be the consequence of these manoeuvres, which are besides, on their first aspect, repugnant to common sense ! (repugnent a la raison).

Instruments.?Before proceeding to these points, the reporter specifies the in- struments used in the treatment of uterine displacements, to which allusion is made. These are of two kinds (sufficiently well known in this country), 1. The Uterine Sound, of Simpson and Kiwisch ; (Recamier and Amussat had pre- viously used a similar instrument). This instrument, which is of undoubted service in diagnosis, is also used to restore the displaced uterus to the normal

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1054.] INSTRUMENTAL TREATMENT OF UTERINE DISEASES. 165

position; but it is nev?r left permanently in the uterus. 2. The pessaries, of different kinds which are used for the replacement and permanent support of the uterus, remaining for a considerable time in its cavity. These are known as Simpson's and Iviwisch's, although the original idea of the invention is claimed for Amussat and Yelpeau. They are 1st, The wire pessary, or pubic pessary, having a stalk to support the interior of the uterus, in connection with an apparatus resting on the pubis. 2d, The spring pessary. 3d, The ball

pessary, with the stalk for introducing it. 4th, The galvanic pessary, made of zinc and copper. 5th, The dilating pessaries, used in obstructive dysmenor- rlioea, sterility, etc. The three last instruments consist of a metallic stalk which is passed into the cavity of the womb, and is fixed on an oval disc or ball. Although the use of the uterine sound is not without danger, it is principally against the intra-uterine pessaries that the criticisms of M. Depaul are directed.

Pathology, etc.?The reporter then enters on the first division of his subject: viz., the Pathology of Uterine Displacements. What is the normal direction of the uterus f What are its displacements f Do these displacements produce the symptoms which have been ascribed to them ? M. Depaul does not agree without reserve with Cruveilhier, and others who maintain that the uterus has no cer- tain direction ; and he rejects the opinion of Boulard and Verneuil, that ante- flexion is the normal position of the womb. He maintains that however liable to vary from accidental causes, the uterus is placed normally in the direction of the axis of the brim of the pelvis. When the axis of the uterus is more inclined in any one direction, we have either ante, retro, or latero-versions. When the whole uterus is pushed from its position, we have total displacement (refoulement), which may also take place forwards, backwards, or laterally. When the uterus is bent on itself, ante, retro, or latero-Jiexions, are produced. There are also, more rarely, flexions of the neck on the body of the uterus ; and inflections of the uterus, where it is curved once, or twice like the letter S italics. Another condition which may exist alone, or combined with the pre- ceding, is the descent of the uterus (abaissement), generally the inferior extre- mity, but sometimes the middle, or possibly even the upper part of the uterus passing low down into the pelvic cavity. These displacements by descent ap- pear to have been overlooked in France by those who used the

" instrumental treatment" (" traitement mecanique ").

These different displacements are so common, that more than half probably of the female sex are subjects of them, and would require treatment, if these conditions were really diseases. But such is not the case ; their influence has been greatly exaggerated, and it may be shown that the symptoms attributed to these deviations belong to some other pathological condition. In a critical

analysis of M. Yalleix's cases of displacement, treated by the intra-uterine pessaries, concomitant disease of the uterus, as hypertrophy and engorgement, or granulations and ulcerations of the cervix, leucorrhoea, etc., are found to have existed in the largest number : in a few, the uterine deviation discovered only after death, had produced no symptoms during life; and in some the morbid symptoms remained after the uterine displacement had been cor-

rected. The cases of M. Gaussail, analysed in the same way, are similarly complicated. The symptoms of all the patients were much alike?viz., un- easiness in walking, pains in the loins, white or sanguineous discharges, consti- pation, and difficult micturition, and disorder of digestion. Yet all these affec- tions are ascribed by M. Valleix and Gaussail exclusively to the displacement, taking no account of the hypertrophy, ulceration, or other diseased state of the uterus, which existed at the same time. The facts of M. Piachaud (pupil of M. Yalleix) are of the same inconclusive stamp as the preceding ; but he adds that he has witnessed dangerous (graves) hemorrhages, and in two cases per- foration of the uterus in consequence of the use of the pessaries !

If in these cases, complicated with other lesions, the symptoms cannot be with certainty referred to the deviation exclusive of the lesions, still less is there evidence to show that the deviations alone give rise to serious symptoms

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166 INSTRUMENTAL TREATMENT OF UTERINE DISEASES. [AUG.

MM. Dubois and Lisfranc declared that displacements were innocuous, unless at- tended with pathological lesion or chronic inflammation. In a number of cases of displacements of all kinds observed by M. Gosselin, at the Lourcine, none of the women had any uterine complaint whatever ; in a number of other cases, where uterine pains existed, there was no displacement, and the pains were owing either to inflammation or neuralgia; and in a third set of cases, where both uterine pains and displacement co-existed, the pains ceased after repose, and the use of antiphlogistics, narcotics, etc., although the displacement persisted. In 27 cases

of simple deviation, observed by M. Depaul, only two had any uterine symptoms whatever; the one (anteflexion) had more frequent micturition, and a sense of weight after long walks ; the other (descent of uterus) had pains in the inside of the thighs, and a feeling of weight in the pelvis, and that only, after fatiguing exertion. Moreover, in diseased states of the uterus, if the morbid

condition of the organ is cured, the painful symptoms entirely disappear; and every day's experience proves, that all the uterine symptoms may be produced by lesions of the organ, unattended by any displacement whatever, to which they could possibly be ascribed. For the truth of the latter statements the

reporter appeals to his own, and to the general experience of the profession. With regard to the influence of the dilating pessaries on sterility, M. Depaul

has similar objections, viz. : that in the facts observed no adequate account has been taken of concomitant pathological conditions; and he maintains that

displacements and flexions could only cause sterility when of very old standing, where the uterus is almost always atrophied, and dilatation consequently useless.

Admitting, however, that in a very small number of cases the mere displace- ment of the uterus may disorder the health, or may have an injurious influence on co-existing diseased conditions, M. Depaul believes that there exist nume- rous efficacious methods of treatment which do not compromise the health or life of patients. Of these means, he enumerates, rest, fixation of the uterus

(immobiliser l uterus), taking off" the weight of the intestines, avoiding tight- lacing, using hypogastric belts, and lastly, the different pessaries (not intra- uterine) particularly that of M. Garriel, composed of caoutchouc distended by air; also stuffing the rectum in cases of retro-version, as practised by M. Huguier. He mentions also the pessaries in whale-bone of Dr Mayer, and that of caoutchouc of M. Joret. He discountenances the use of cauterisations to

produce adhesions for the purpose of replacing the uterus. Cases.?The most interesting inquiry in a practical point, however, is an ex-

amination of the statistics of the treatment by intra-uterine pessaries. The number of cases published amounts to about 180, and of these, according to M. Valleix, 129 were cured. A result, at first sight, so strongly in favour of the treatment, is, however, completely reversed by the history of the cases themselves. The

reporter here gives a short analysis of M. Yalleix's cases, twenty in number, of five cases by M. Gaussail, and three by M. Piachaud. With regard to Dr

Simpson's practice he was unable to give the results, as that gentleman, when applied to, had, he said, communicated only assertions without proofs; he could only, therefore, give an idea of his success from the information received from indirect sources.

It would be tedious to give the whole of these cases ; we subjoin a few to show the method of analysis, and how inconclusive the cases are, or rather how they are turned into evidence against the treatment they were published to recommend.

Yalleix's cases.?Fifth case. C-., set. 31, some years after accouchment suf- fered from hysteria, leucorrhoea, fatigue in walking, and weight in the pelvis, for which she was treated by repeated leeching. Coming under M. V.'s care in 1851, she was pale and anemic; the uterus was voluminous, not painful, lying tranversely forwards. On the anterior lip, which was red and voluminous, there was a prominence of a deeper colour, presenting in the middle a little white point. The neck was cauterised on three successive occasions with the acid

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1854.] INSTRUMENTAL TREATMENT OF UTERINE DISEASES. 167

nitrate of mercuiy. Afterwards, the catheterism was practised six times, leav- ing three or four days interval. At the end of a month the uterus was replaced in its normal situation. The cauterisation was then resumed and repeated thir- teen times during nearly two months. There was no accident, and the cervix was cured. That cure, ascribed to the uterine sound, ought plainly to be attributed to the cauterisations. Several of the other cases are very similar to this.

Ninth case. Anteflexion with hypertrophy, the uterus being heavy, with little mobility, the sound penetrating seven centi-metres. The intra-uterine

pessary (redresseur) having occasioned dangerous symptoms, an energetic anti- phlogistic treatment was employed, in consequence of which the patient was cured.

Thirteenth case. Retroversion, and chronic metritis with ulcerations and numerous red granulations. The intra-uterine pessary was applied once, and left in for a fortnight; long after this the patient underwent treatment for anemia, neuralgia, and for a fissure of the anus which had been overlooked at first. The cervix was cauterised for several months.

In others of his cases there appears insufficient evidence of the state of the uterus, or even of the cure which is reported to have ensued. M. Gaussail's cases are generally complicated with metritis, and such varied and prolonged methods of treatment were used, that it is difficult to ascribe the cure to any one in particular. His fifth case he concludes by admitting that

" the treatment {by intra-uterine pessaries) had produced no amelioration,?the patient felt more fatigued in zoalking, standing, or by simple movement of the arms. The modifi- cations in the position of the uterus were hardly recognisable. The patient and the medical man were convinced that this treatment could no longer le endured." M. Piachaud's cases have already been alluded to. In addition, two cases are quoted, observed by M. Gaube, in which all the morbid symptoms were cured, although the use of the pessary failed to replace the uterus. The last case given is one of anteversion, where the patient, dismissed cured

from hospital by M. Yalliex, returned next day in as bad a condition as ever. Scanzoni, in Canstatt's Jahresbericht, states that in twenty cases of displace- ment, where he tried the mechanical treatment, he did not once obtain a per- manent cure. It appears, moreover, that M. Yalleix has been continually improving the intra-uterine pessary, by diminishing the length of the uterine stalk, till at last he has given it up altogether, and uses only the temporary introduction of the uterine sound, but always, he assures us, with the same suc- cessful results.

Having examined the statements of the principal partizans of this mechanical treatment in France, viz., MM. Valleix, and Gaussail, etc , M. Depaul proceeds to show that this treatment has no greater favour or success in other countries, particularly Great Britain. In regard to Dr Simpson's practice, he quotes from an eye-witness, that although in many cases the relief is immediate, and in a few instances the instrument can be worn with impunity for months or even years, yet in the great majority of females seme morbid state of the uterus or its appendages, etc., comes on; hemorrhages, rectal fissures, ulcerations of the rectum, metritis, metro-peritonitis, pelvic abscesses were pretty frequent con- sequences, and more than once death was the final result. Drs Churchill, Ashwell, and Gream's statements are quoted as to the dangers of the treatment, together with Dr Robert Lee's case, where the pessary, or, as he calls it, the impaling machine, was extracted from the uterus. Two fatal cases of peri- tonitis caused by the pessaries, described by Dr Oldham; his strongly ex- pressed opinions against the practice ; the similar views of Montgomery of Dublin, and Matthews Duncan of Edinburgh, are adduced as strong evidence of the unfavourable estimation in which the practice is held by a large number of eminent obstetricians. The same objections which have been made to the pessaries are also appli-

cable to the uterine sound or." catheter (liysterometre), especially when used to replace the uterus in position. According to Depaul, in the vast majority, of

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168 INSTRUMENTAL TREATMENT OF UTERINE DISEASES. [AUG.

cases it is unnecessary even for diagnosis; it may even lead into error, and its use is not exempt from serious dangers. Gueneau de Mussy has recorded a case of fatal peritonitis in consequence of passing the uterine sound ; three cases of abortion in the early stage of pregnancy, and one case of abortion and death has occurred in the practice of Huguier, Nonat, and Valleix. M. De-

paul then passes under a final review the cases of Valleix, Gaussail, Piachaud, Huguier, Nonat, etc., and finds in nearly every one some of the following results from the use of the intra-uterine instruments : hemorrhages nearly in every case, and sometimes of dangerous amount ; uterine and abdominal pains ; rigors and fever ; syncope and phlegmonous inflammation around the uterus, or in the iliac fossa ; metro-peritonitis. A case of enormous phlegmon in the neighbour- hood of the uterus is given in detail from M. Cazeaux ; one of metro-peri- tonitis from M. Gaube ; six cases (one fatal) from M. Nonat, in none of which was the displacement benefitted by the treatment, which gave rise to the dan- gerous complications, pelvic abscesses, metro-peritonitis, etc. ; and this enume- ration is summed up by the fatal cases of MM. Broca and Cruveilhier, which originated the inquiry before the academy ; followed by four fatal cases from the practice of MM. Valleix, Nelaton, and Aran, and the testimony of M. Maisonneuve that similar accidents have occurred in his hands.

Conclusion.?From these detailed investigations the reporter draws up the following conclusions as the unanimous opinion of the committee :?

In the great majority of females, uterine displacements do not injure the health, and constitute a mere deformity without importance. Where displace- ments co-exist with inflammation or neuralgia, when the latter affections are cured, the former disappear, or if they persist are quite innocuous. The small number of simple displacements which occasion inconvenience are easily and safely treated by simple methods without incurring the dangers of the intra- uterine instruments, which, even when they momentarily replace the uterus, fail to fix it in the normal position. The facts adduced to show the efficacy of the mechanical treatment have been wrongly interpreted, and the cures as- cribed to it have been owing to other means employed at the same time. The

fatal cases observed both in France and England are numerous enough to show the perils of this treatment, and to warn its boldest partisaifs. In addition to the mortality, the other dangers are of the most alarming kind ; pains, some- times agonising, hemorrhages, anemia and nervous disorders, rigors, fever, syn- cope, peritonitis, pelvic abscesses, metro-peritonitis, etc., not to mention the cases where the treatment could not be endured. The uterine sound, of great advan- tage in the diagnosis of certain affections, is very often of no service, and from the great risks attending its use, should be reserved for the exceptional cases which require it ; aud, finally, that the different intra-uterine pessaries ought to be proscribed, because they are useless, and impotent to produce the good effects expected from them, and they subject the patients to the most serious dangers.?Bulletin cle VAcademie, 81st May 1854.

DISCUSSION ON M. DEPAUL's REPORT.

After some remarks from M. Piorry, the discussion was opened by M. Mal- gaigne, who, while admitting the zeal and talent of the reporter, regretted to find so much party spirit in the report, which more resembled the impassioned argument of a special pleader, than a plain and impartial judgment of facts. He could not consider as repugnant to common sense a treatment, which had been practised by Velpeau, Amussat, Simpson, Huguier, and Valleix. It ap- peared even from the report that in some cases, the intra-uterine pessary had been useful, and sometimes it had procured instantaneous relief, showing that the symptoms were really owing to displacement, and he had often witnessed cases of descent of the uterus, where the use of a pessary had put a stop to all the symptoms; the hypogastric belt also, by replacing the uterus, had often produced the same beneficial results. It appeared to him, that the important inquiry was to establish a differential diagnosis of uterine affections ; since the

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same symptoms were ascribed by some exclusively to displacements, by others exclusively to enlargement {engorgement), by others to granulations, ulcera- tion, etc., etc. In neuralgia of the uterus, the pessary, he thought, might certainly be serviceable. In short, the intra-uterine pessaries ought not to be entirely rejected, but their use should be restricted to cases without inflamma- tion, acute or chronic, the instrument should be employed cautiously, and not be allowed to remain permanently ; and, above all, the treatment should be controlled according to rational indications ; the practitioner should know what he does and why he does it.

M. Depaul, in reply, stated, that by the expression repugnant to reason, he meant no more than that a priori considerations were opposed to this method of treatment. He defended the report against t.he objections of M. Malgaigne, and answered some statements which M. Gaussail had addressed to the

Academy ; he maintained the impartiality and justice of his criticisms. M. Huguier, who had not signed the report in consequence of differing from

M. Depaul in some of his conclusions, made a full and able statement of his views. With regard to the intra-uterine pessaries, he thought that they ought not to be entirely rejected ; but that their use should be confined to those

exceptional cases of displacement giving rise to serious symptoms, which resist other means of treatment, that their application should be made with great caution and carefully watched. He especially commends their efficacy as

emmenagogues, when other means have failed. On the pathological question, he explained the circumstances under which uterine displacements occasion no symptoms ; and after distinguishing the local and sympathetic affections which are occasioned by inflammations, etc., of the uterus, he defines those symp- toms which properly belong to and are occasioned by uterine displacement, particularly disorder of the menstruation, and distressing affections of the bladder and rectum (frequent micturition, retention, obstruction of the rectum, etc.) He considers that deviations, especially ante and retro-flexion, may occasion sterility; and maintains that the displacements are undoubtedly curable. In conclusion, M. Huguier relates his experience of the general and local treatment of the displacements by pessaries, etc., and describes the methods by which he has succeeded in replacing the uterus when retro-flexed by the insertion of pledgets (meche) of lint in the rectum.

M. Hervez i>e Ciiegoin was of opinion, that the displacements may occasion most distressing symptoms, which are only to be relieved by replacing the organ. But this result ought to be accomplished by vaginal pessaries external to the uterine cavity. The intra-uterine pessaries had produced so many serious accidents, that he was surprised any one could follow a method attended with such risks. He considered that they ought to be altogether dismissed from practice.

M. P. Dubots denied that the vaginal pessaries recommended by M. Chegoin, could ever effectually replace a retroverted uterus; consequently, he con-

sidered the intra-uterine instruments to be perfectly rational, and indeed, the only means capable of effecting the end in view. The only question was are they without danger ? It is certain that their introduction frequently gives rise to severe, sometimes even fatal consequences; sometimes the instruments

cannot be tolerated; while, in some cases, they are quite innocuous, and occa-

sionally their use is attended with immediate, or even permanent, relief. M.

Dubois, however, maintains that in no instance do they ever attain their pro- posed object ; the uterus is never replaced permanently in position by their use. This assertion he supports both on theoretical giounds, and by the result of his examination of cases treated by himself, by Valleix, and by Simpson. Although, however, the displacement is never removed by this method, the uterine symptoms 'may be alleviated or even cured by it. These results are

owing to the pessary relieving the weight of the uteius, and the tension of its ligaments; to the alteration in the morbid action by contact when the uterus NEW SERIES.?NO. LVI. AUGUST 1854. Y

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170 INSTRUMENTAL TREATMENT OF UTERINE DISEASES. [AUG.

is inflamed, and to the alteration of its morbid sensibility in cases of neuralgia. In the latter class of cases the method is of particular service, and often re-

lieves all the symptoms, even where no deviation had existed. Many of M. Valleix's cures occurred in cases of neuralgia. Consequently, the intra-uterine pessaries ought to be retained in practice, not as directors of the position of the uterus, but as modifying agents which may be placed in competition with other efficacious means already known as such, cauterisations, douches, etc. And in all cases, the general treatment should be attended to as well as the local, a principal condition to which M. Yalleix owes much of his success. M. Cazeaux expressed his opinions at great length. He objected to the report

for stating the unfortunate and fatal cases, and omitting the successful ones. He admitted that by removing the displacements, both the symptoms which it

occasions, and even the concomitant lesions, granulations, etc., may be cured. In opposition to M. Dubois, he maintained the efficacy of the (M. Chegoin's) vaginal pessaries in retroversion ; and he considered inflexion to be a congenital condition in the child, adopting the opinion of Boulard, Follin, and Verneuil. He is opposed to the intra-uterine pessary, as mostly useless and often dangerous, but he considered that the uterine sound, with proper precautions, may be ren- dered safe, and is of real service. M. Gibert maintained that too much importance had been attached to

uterine diseases altogethei-, and great illusions existed in regard to them ; that

they often depended on constitutional states ; and he mentioned instances of several diseases of the uterus, where erroneous and overstrained views of their

pathological consequence had led to methods of treatment as severe and dangerous as they were useless and uncalled for.

M. Velpeau, in one of the most important addresses delivered in the dis- cussion, entered at considerable length into the details of the question, and opposed in decided terms, the conclusions of M. Depaul's report. He passed a high eulogium on M. Valleix, and attached great importance to the results of his practice. He maintained that practitioners have not exaggerated the effects of uterine displacements, nor have they attributed to them those affec- tions which resulted from other pathological conditions. Wherever disease of the uterus, enlargement or engorgement (if not mistaken for anteflexion, as has often happened^, or ulceration, or leucorrhoea occurred, no practitioners could overlook these conditions or confound them with the effects of simple uterine displacement. And, although there may be cases of uterine displace- ment, without urgent symptoms, just as there is hardly any important organic disease the symptoms of which may not be latent, still no one could doubt the serious affections which may be caused solely by uterine displacements, and may be removed by replacing the uterus. M. Velpeau was convinced, that although these deviations yielded, in general, a favourable prognosis, yet that they pro- duced, especially in nervous women, affections of real danger. M. Velpeau next examined the means of remedying these affections, enumerated by M. Depaul and others ; and while, recognising their usefulness in certain cases, he was quite persuaded of their radical inefficiency. In consequence of this conviction, he had himself long ago attempted the use of intra-uterine pessaries, but had desisted after the trial of a few months, being deterred more by theo- retical considerations, than by the results of practice. He now thought that the dangers of these pessaries had been exaggerated, and might be avoided by more careful and experienced manipulation. The intra-uterine pessaries had not indeed solved the difficulties in the radical treatment of uterine displace- ments, but they had already rendered great services, and would with further experience render more ; they ought not to be rejected, but their employment ought to be regulated judiciously; and he trusted to the experience of M. Valleix to disclose the advantages and the disadvantages which belonged to this method of treatment. M. Velpeau was of opinion that the conclusions of the report ought to be suppressed, and that the Academy could only vote in reference to the cases brought forward by MM. Broca and Cruveilhier.

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1854.] ON ECLAMPSIA DURING PREGNANCY. 171

M. Depaul explained that the conclusions already given were merely the Bumming up of his report, and that he would, after the discussion was finished, submit to the Academy a series of conclusions embodying the unanimous opinion of the committee. ,

[The discussion is not yet terminated, hut we shall conclude the subject, and, we trust, with a commentary by Professor Simpson, in our next number.]

BItAUN ON ECLAMPSIA DURING PREGNANCY.

Tiiis author has recently published a lengthy paper on the above interesting subject, of which the following is a very brief abstract :?

Isi, Convulsions may arise, during this period, from hysteria, epilepsy, cerebral diseases, poisons, or uraemia,?resulting from Bright's disease.

2d, Their most common causes are uraemia and Bright's disease. 3d, The least frequent causes are primary cerebral diseases; and when these

occur in connection with albuminous nephritis, they are the results, not the causes, of the convulsions.

4th, Hysteria and epilepsy may exist, during gestation, in a chronic form, so as to exercise no injurious influence either on pregnancy or labour, or on the life of the child ; and the}' may be quite unconnected with Bl ight's disease.

5th, Convulsions in every form may occur from these causes in the unim- pregnated female ; and also in men, from all of them, except hysteria.

6th, The altered constitution of the blood, and the detention of the venous blood in the kidneys by the pressure of the enlarged uterus, are most com- monly the causes of the Morbus Brightii, which occurs during pregnancy.

7th, Convulsions are caused by the urea, which is uneliminated from the blood on account of the renal disease, becoming changed into the carbonate of ammonia.

8t/i, When, in cases of Bright's disease during pregnancy, we find carbonate of ammonia in the blood, we may prognosticate the occurrence of convulsions ; but when, at this time, the urea in the blood exists merely in small quantities, or chemically unchanged, we need not dread eclampsia.

9th, Parturition and uterine irritation neither cause this chemical transfor-

mation, nor occasion uraemic eclampsia. I Oth. The abortions which so frequently happen during uraemic convulsions,

are the results, not the causes of the eclampsia. II th, There is no connection between eclampsia and labour-pains. 12th, Albuminuria does not result from convulsions arising from functional

interruptions, and does not generally occur in those of an epileptical and hysterical character.

13?/', Albuminuria continues throughout pregnane}*, although the eclamptic attacks may have ceased : but when convulsions cease after labour, it soon

disappears, provided the renal disease be only in the incipient stage. 14th, The disappearance of the albuminuria after parturition, is principally

due to the diminished volume of the uterus.

1 oth, Morbus Brightii (without convulsions) may be palliated, but not re-

moved, during pregnancy, although it readily yields to remedies after partu-

rition. 16*/t, Albuminuria occurs in all cases of eclampsia which do not depend upon

hysteria, epilepsy, primary cerebral diseases, or poisons. 17th, Epileptic convulsions may occur simultaneously with those from

Blight's disease and uraemia. 18th, Uraemic convulsions, when frequently recurring, occasion the death of

the foetus ; but its life is not endangered by those from hysteria or epilepsy. 19th, During an attack of uraemic eclampsia,

reflex sensibility is almost ?wholly suspended; and after it we oftener find cedema and anaemia of the

brain, than hyperaemia and consecutive apoplexy before it.

20th, Venesection (according to Kiwisch, Litzman, Sedgwick, Blot, and

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172 CONTRACTION OF VAGINA AND OS TINCiE. [Aug.

King) is injurious in eclampsia ; and the author has found its action very un- certain in uraemia. He considers inhalations of chloroform to be the best and safest means we possess for subduing and removing uraemic convulsions, both during pregnancy and after labour.

21 st, The most certain diuretics for removing the uraemia of Bright's disease are the benzoic, tartaric, and citric acids.

22c?, The artificial induction of premature labour diminishes the danger of uraemic eclampsia alike to the mother and child ; but this practice should not be universally resorted to in cases of Bright's disease during pregnancy, but only when necessitated by the occurrence of convulsions. Biaun considers the

tampon as the best method for its induction when necessary.

[The treatment here proposed appears to us by no means universally appli- cable. Where the convulsions occur during pregnancy, or in an anaemic patient, or where, as happens in infantile eclampsia, they depend rather upon a super- polarity of the cerebro-spinal system than on actual toxaemia, we consider the inhalation of chloroform as unquestionably the best treatment for arresting the paroxysms. But when, on the other hand, they occur during "parturition, or in the puerperal state, in a robust, plethoric patient, we should be inclined, from all we have seen of the disease, to place more confidence in copious vene- section, smart purgatives, and cold to the head.

Moreover, for the induction of premature labour in such cases, we should be inclined to prefer the use of sponge-tents and uterine douches to the clumsier method of the tampon.] DRS PRICHARD's AND PAGAN'S CASES OF DIFFICULT LABOUR ARISING FROM EXTENSIVE

CONTRACTION OF THE VAGINA AND OS TI.VC.d3.

On the evening of the 13th October 1852, I was requested to visit Mrs Bra- nagan, a;t. 25, residing in Partick. I found her considerably emaciated, and suffering from occasional uterine pains, though not of an expulsive character. She mentioned to me that she had just completed her seventh month of preg- nancy, and expressed much fear and anxiety about her state. I enjoined the recumbent posture, and ordered her an opiate.

October 14ill.?Had a quiet night, bowels opened, urine passed freely. Uterine pains continue. The opiate to be repeated.

11 o'Clock p.m.?Since last visit has been suffering from severe expulsive pains at regular intervals ; complains of debility and nausea. Pulse 120, skin hot, thirst urgent. When examined, pervaginam, the passage was found con- tracted from cicatrices, to such an extent as scarcely to allow the introduction of a finger. The os tincsc was very rigid and partly dilated, the cervix being bound to the posterior wall of the vagina, by a broad cartilaginous band. The head of the child was readily felt by the introduction of a finger into the anus. Expulsive pains continuing at regular intervals, without producing any dilata- tion, and the patient losing strength, I determined upon instrumental delivery, and requested the assistance of my friend Professor Pagan. A firm band, about two inches broad, perfectly undilatable, extended across the posterior wall of the pelvis. To this, what remained of the vaginal portion of the uterus (its an- terior lip) was attached. Dr Pagan introduced a finger into the rectum, and with a blunt pointed bistoury cut the band as deeply as safety would permit Very little space was gained by this incision, and four others were made, two on either side of the pelvis. A considerable amount of blood escaped. In con-

eequence of the attachment of the anterior wall of the cervix uteri to the cica- trices, comparatively little space was gained by these incisions, and Dr Pagan determined, therefore, to slit up the anterior lip. Having done this, he was able to pass a couple of fingers into the vagina, and by them to guide the blades of the forceps along the sides of the child's head, when, applying very consider- able extracting efforts, he fairly tore the head through the contracted vagina. The child, a female, was born alive. A little warm spirits and water were given the mother, and she was left at four a.m.

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1854.] STRUCTURE OF THE FUNDUS UTERI. 173

October 15th, 11 o'clock a.m. Has had some sleep. Pulse 120; skin moist ; lochial discharge moderate ; no thirst; has passed urine. Child well, and has taken some milk and water.

Evening.?Pulse 120 ; skin cool; tongue moist ; ordered an opiate. She continued to improve, although slowly, it being a month before she was

able to be out of bed, and nearly another month before she was quite recovered. The incisions slowly healed, the vagina remaining much contracted. There was no secretion of milk. On inquiring into the history of her previous confinement, I found that she

had been delivered on 25th December 1847, of a still-born child, after a severe labour of three days. The perineum had been lacerated, and she suffered great pain, and laboured under stillicidium urince for upwards of two months after her delivery. It is probable that there had been much sloughing of the vagina, which would necessarily be followed by the great .'contraction described as ex- isting at the time of her second confinement. Note by Dr Pagan.?Since Pr Prichard's case, one nearly similar occurred

among the poor women attended from the hospital. The patient was in labour of her second child when seen by me, and believed herself to be between the sixth and seventh month of pregnancy. Upon introducing the finger within the orifice of the vagina, a perfectly undilatable falciform band extended en- tirely across the pelvis, merely permitting the introduction of the finger be- tween this and the anterior wall of the pelvis. The breech of the child, which was presenting, and which was at first mistaken for the os and cervix uteri, was directed against this aperture, but even under vigorous pains no progress had been made in the dilatation of this preternatural band, during many hours con- tinuance. Free incisions were made, as in Dr Prichard's case, and these per- mitted the expulsion of a still-born premature child. The patient made a per- fectly good recover}^.

This woman was delivered by the perforator, after being long in labour of her first child. She was the victim of a vesico-vaginal fistula, and no doubt the

cartilaginous-like band, which occupied so large a space in the pelvis in her second labour, had replaced the natural structures destroyed by sloughing after her first.?Glasgow Medical Journal.

[We highly approve cf Dr Pagan's practice in these cases, but have had some difficulty from Dr Prichard's description in understanding the nature of the lesion, and how the first incisions were made.]

DR DIEZ ON STRICTURE OF THE FUNDUS UTERI AS A CAUSE OF DANGEROUS HEMORRHAGE.

Under this new title the author alludes to a description of haemorrhage that most experienced practitioners are familiar with as arising from partial contrac- tion of the uterus. After the separation of the placenta, and while globular contraction of the uterus can be felt above the pubes, alarming haemorrhage comes on. As there is good contraction of the uterus, and pains, often of con- siderable severity, occur, this is at first inexplicable. On passing the hand

through the widely-opened os, we enter a tolerably spacious cavity filled with

coagula, whose walls are firm and unyielding, and remain quite passive to the pressure of the hand. Pushing on further, we perceive a more or less narrow, often cartilage-like stricture, separating the fundus from the body of the uterus. It is exactly?the same as is observed in strong incarceration of the placenta, only, as a general rule, the contracted part is inclined to one side (usually the right), and takes on a more oval form. The means calculated to check hemorrhage under other circumstances are

here useless or mischievous. Increasing the pains by means of ergot, cold, ex- ternal pressure, friction, etc., does injury by increasing the abnormal contrac- tion, and by favouring the flow of blood from the non-contracted part. Of a more useful character are such means as tend to arrest haemorrhage without exciting pain, as compression of the aorta (taking care, however, not to com-

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174 CASE OF SUCCESSFUL OVARIOTOMY. [Aug.

press the fundus uteri), acids, alum, cinnamon, ipecacuanha, warm astringent injections, etc. The most efficacious means, however, is the attacking the pa- thological condition upon which the haemorrhage depends, by the employment of belladonna, in conjunction with, or in quick succession with, ipecacuanha, together with compression of the aorta. When, on account of pressing danger, the operation of these means connot be waited for, the painful and often diffi- cult procedure of dilating the strictured part must be resorted to, allowing the hand to remain within the fundus until the organ contracts in a normal

manner.?Monatsbericlit fur GeburtsJcunde, Band ii. p. 1.

[The use of remedies such as belladonna and ipecacuan is too feeble a mea- sure against any dangerous form of haemorrhage after delivery. The use of the ordinary means for exciting the relaxed portions of uterus to contraction will, of course, be useful. Of these cold frictions, ergot should certainly be re- sorted to in the first instance.]

PROFESSOR IIOHL's CASE OF DOUBLE UTERUS, WITII TWINS, AND PLACENTA PRAEVIA.

A delicate woman, aged 30, was subject, during the first three months of her second pregnancy, to periodically recurring attacks of uterine hemorrhage, which, although easily checked at that time, returned more violently in the seventh month. At this period her abdomen was found very much distended at both sides, but level in the central region extending from the umbilicus to the symphysis pubis. Percussion yielded a tympanitic sound in this hollow, and a dull sound on either side. An inch and a half above the pubis the uterus could be felt distinctly, through the parietes, dividing into two parts, of which the one on the right side was largest. Both were convex on their internal, and somewhat concave on their external surfaces ; and each re-

sembled in appearance the normal gravid uterus at the full time. In each, the foetal heart could be distinctly heard on auscultation, and the form of a child easily felt by external tactile examination. On internal exploration, the

vagina was found quite normal; and at its roof the cervix was felt, short and broad, and having two ora uteri, through both of which the presenting parts of the children could be distinguished. Over the right os uteri was situated one of the placenta;, and a portion of the other projected from the left os. On account of the violent uterine hemorrhage, Ilohl induced premature labour, and delivered the children by turning. The right placenta was spontaneously detached, but that on the left side adhered so firmly, that it had to be artifi-

cially separated. The twins, who weighed three lbs., died almost immediately after their birth. Subsequent examinations of the uterus, with the sound and the finger, confirmed the correctness of the original diagnosis.?Deutsche Kli- niJc. I. 1853.

[This is one of the most singular cases on record. Lately the medical jour- nals have contained notes of two cases of pregnancy occurring in a rudimentary uterine horn, described by Rokitansky and Scanzoni. The women died from

rupture of the horn (just as happens in cases of tubal pregnancy), and the cases were subjected to post mortem examination and verification.]

PROFESSOR LANGENBECR's CASE OF SUCCESSFUL OVARIOTOMY.

An unmarried female, set. 34, had, for five years, had a gradually enlarging ovarian tumour, which at length attained so great a size that the abdomen was as distended as it is at the end of pregnancy. This tumour extended from the

pelvis to below the false ribs ; it was easily moveable, and was distinctly fluc- tuating to the touch. At the desire of the patient, and under the influence of chloroform, the operation of ovariotomy was performed. A finger's breadth above the symphysis pubis, an incision of 2\ inches was made through the in- teguments of the abdomen, nearly in the line of the linea alba. The cyst, being seized with hooks, was first punctured by a trocar, which evacuated nearly 9

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quarts of clear limpid fluid, and thereafter it was pulled out until the pedicle of the tumour was completely exposed. The abdominal incision was closed with six sutures ; strong double ligatures were then passed through and tied round the neck of the tumour ; and next, a ligature was passed both through the pedicle and the lips of the wound. Finally, the tumour was removed by cutting through its stalk, immediately above the ligatures. The tumour pre- sented one very large cyst; on the extirpated ovary there were two smaller cysts, the size of hazel-nuts, and the Fallopian tube was adherent by its fim- briated extremity. The evacuated fluid contained merely a few epithelial cells, and it coagulated readily with heat. The wound cicatrized in nine

weeks, and during the healing process the patient was considerably troubled with colic pains.?Deutsche Klhiik. No. 4. 1853.