pre “rehab” nutrition beth hall rd, cso, ln billings clinic 2014

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Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

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Page 1: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Pre “Rehab” Nutrition

Beth Hall RD, CSO, LN

Billings Clinic

2014

Page 2: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Prehab Enteral Nutrition

1. Identify 3 nutrition interventions from the ERAS protocol

2. Identify the nutrition triggers from Strong for Surgery

3. Identify high risk surgical populations that may benefit from early nutrition support

Page 3: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

“Prehabilitation”

• Metabolic Assessment1-4

– Glycemic Control (HgA1C >7-8%) 1

– Weight loss ( BMI >35) 1

• Surgical complications are 12 X in obese pts1 • Individual exercise program• Preserve lean body mass

– Smoking Cessation• 30 day cessation reduced site dehiscence from

approximately 12% to 2%1-4

– Immune enhancing nutrition 5-7 days3,4

• 36% reduction in infectious complications• 18% reducation in non-infectious complications

Page 4: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

ERAS

• Enhanced Recovery After Surgery

• Perioperative Care to improve outcomes after major surgery1,5

• Decreased length of stay by 2-3 days1,5

• Decreased complications by 30-50%1,5

Page 5: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

ERAS SURGICAL POPULATOINS

• Bladder6-8

• Colonic/Colorectal9,10

• Esophageal11

• Head and Neck Cancer12 • Hepatic13 • Gastrectomy (Laprascopic)14

• Gynecological Cancer/Hysterectomy15,16

• Pancreaticoduodenectomy17,18

Page 6: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

ERAS OVERVIEW5

(Ljunqvist, 2014)

Page 7: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Nutritional Prehab ERAS

• NPO 6 hrs pre-op solids, 2 hrs clear liquids4,5,9

• Oral Rehydration Solution – 120 g CHO drink night before and 2-3 hrs pre-

surgery (09 Guidelines) 5

– 800 mL CHO drink night before and 400 mL 2-3 hrs (12.6 g CHO/100 mL) 5,10

– Nutrition status optimized with liberal nutrition support

• Nutritional supplements

Page 8: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Post-operative Nutrition ERAS

• Oral fluids as tolerated on the day of the surgery and built up to oral diet over nexct 24 hours 5,9

• Goal to meet nutritional needs within 72 hours 5,9

• Avoid excessive IVF (1.5-2.5 L/day should be adequate) 5,9

Page 9: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Strong for Surgery

http://www.becertain.org/strong_for_surgery

Page 10: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Strong for Surgery

Nutrition Parameters:

STRONG FOR SURGERY RD CONSULT FOR YES

BMI less than 19 C/S

Weight loss 8 # or more over 3 months

C/S

Less than 50% of 2 or less meals per day

C/S

Is the patient un able to take food C/S

Is patient having a complex surgery C/S, Nutritional Supplement

http://www.becertain.org/strong_for_surgery

Page 11: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

CASE REVIEW

Page 12: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

CASE REVIEW

Page 13: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

High Risk Prehab Nutrition

• Colorectal 5-7 days pre-op

• Whipple 5-7 days pre-op

• Esophagectomy – 2 weeks pre-op

• Obesity pre-op – 1 – 3 months pre-op

• All feeding tubes 5-7 days pre-op

Page 14: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

CASE REVIEW

Page 15: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

High Risk Prehab Nutrition

• Bezoars• Celiac Disease • Cancer• Cirrhosis• Colostomy • Crohn’s Disease • Divertulosis • Dysphagia• Eating Disorders

• Esophagectomy

• Esophagitis

• Feeding tube

• Fistulas

• Gastrectomy

• Gastroenteritis

Page 16: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

High Risk Prehab Nutrition

• Gastroparesis

• GERD

• Ileostomy - 3 month care

• Inflammatory Bowel Disease

• Lactose Intolerance

• Malabsorption

• Malnutrition

• Parenteral Nutrition• Pre-operative weight loss• Short Bowel Syndrome • SMA• Ulcerative Colitis • Whipple • Wounds

Page 17: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Presurgical Weight Loss

• BMI has been associated to surgical wound complications 1,19,20

• Obesity defined at % body fat has been associated with a 5-fold increase in surgical site infections19

– Using BIA 69% were identified as obese• Reference Measurement - Men (0.85) Women

(0.88)

– Using BMI 38% were identified as obese

Page 18: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

IBD Prehab EN

• Surgical Consult = Nutrition Consult• Considerations from the British Dietetic

Association21:– When medical therapy is contraindicated– Patients of physicians choose this treatment option– Corticosteroids should be avoided (young adults)– Patients present with or are at high risk for malnutrition

Page 19: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

IBD Prehab EN

• EEN remission rates 50-80% in children and young adults22

• Partial EN with an alternative diet (50%) led to 70% remission rate22

• Partial EN with a free diet led to a 15% remission rate22

Page 20: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

IBD Prehab EN and Labs

• CBC

• Iron deficiency – Serum Fe – TIBC– Ferritin

Page 21: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

• Vitamin D may impact response to IBD treatment23-26

– Desired level <30– Repletion 50,000 q wk x 8 wk, 1-2 x mo, 3 month

checks– Maintenance 1000 IU/day

• Calcium25

– Calcium citrate divided into dosing 2-3 times per day– 1200-1500 mg/day

IBD Prehab EN and Labs

Page 22: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

• Zinc25 – More often with high output fistulas and parenteral

nutrition dependence related to short bowel syndrome– 12 mg of zinc should be added for each liter lost

• Magnesium25

– Oral options; Mg gluconate, Mg sulfate, Mg oxide, Mg chloride

– For severe depletion IV replacement with slow infusion to improve

IBD Prehab EN and Labs

Page 23: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

IBD Prehab Nutrition

• Vitamin B1225

– Normal Range (200-900 ng/L)– Repletion

• 1000mcg (IM injection)• 1000 mcg (subcutaneous injection weekly)• Oral synthetic B12 (1000-2000mcg/day)

• Folate25

– 1 mg oral folic acid daily in patients with high homocysteine level and those on methotrexate

Page 24: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

CASE REVIEW

Page 25: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

Prophylactic Feeding Tubes

• Prehab EN is critical in the cancer population– Head and Neck Cancer– Esophageal Cancer– Pancreatic Cancer Tx plan whipple and

chemoradiation

Page 26: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

High Risk Moderate Risk Mild Risk

Malnutrition

Weight lossIncluding Pretreatment

10-15% in 6 months 10% in 6 months

5% in 1 month

BMI <16 16-17.9 18-20

Albumin <2.1 g/dL 2.1-2.7 g/dL 2.8-3.5 g/dL

Prealbumin < 5mg/dL 5-10 mg/dL 10-15 mg/dL

Penetration/Aspiration Scale* Level ≥ 5 Level ≥ 3 Level ≥ 2

Dysphagia* Grade ≥3 Grade ≥2 Grade 2

Location Bilateral neck disease planning treatment

Oropharynx, hypopharynx, larynx, nasopharynx, or base of the tongue

Performance Status* ECOG score ≥3 ECOG ≥2 ECOG ≥2

Karnofsky < 80 Karnofsky < 80 Karnofsky < 80

Other Limited Care Giver Support VEGFR medications

Tracheotomy Pharyngeal Tumor Site

If all 3 present 75% risk: 1. Smokes 20 cigarettes per day

1. Cancer Stage 3-4

1. Poor Performance Status

Billings Clinic Cancer Center Head and Neck Cancer EN Risk AssessmentStage T3 or T4 and/or N2 or N3

Page 27: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

CASE REVIEW

Page 28: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

References• 1. Martindale RG, McClave SA, Taylor B, Lawson CM. Perioperative nutrition: what is the current

landscape? JPEN J Parenter Enteral Nutr. Sep 2013;37(5 Suppl):5S-20S.• 2. Drover JW, Dhaliwal R, Weitzel L, Wischmeyer PE, Ochoa JB, Heyland DK. Perioperative use of

arginine-supplemented diets: a systematic review of the evidence. J Am Coll Surg. Mar 2011;212(3):385-399, 399 e381.

• 3. Marimuthu K, Varadhan KK, Ljungqvist O, Lobo DN. A meta-analysis of the effect of combinations of immune modulating nutrients on outcome in patients undergoing major open gastrointestinal surgery. Ann Surg. Jun 2012;255(6):1060-1068.

• 4. McClave SA, Kozar R, Martindale RG, et al. Summary points and consensus recommendations from the North American Surgical Nutrition Summit. JPEN J Parenter Enteral Nutr. Sep 2013;37(5 Suppl):99S-105S.

• 5. Ljungqvist O. ERAS—Enhanced Recovery After Surgery: Moving Evidence-Based Perioperative Care to Practice. Journal of Parenteral and Enteral Nutrition. July 1, 2014 2014;38(5):559-566.

• 6. Patel HR, Cerantola Y, Valerio M, et al. Enhanced recovery after surgery: are we ready, and can we afford not to implement these pathways for patients undergoing radical cystectomy? Eur Urol. Feb 2014;65(2):263-266.

• 7. M'Baya O, Vlamopoulos Y, Hubner M, Blanc C, Jichlinski P, Cerantola Y. [Enhanced recovery after surgery applied to cystectomy patients]. Rev Med Suisse. Dec 4 2013;9(409):2279-2282, 2284-2275.

• 8. Cerantola Y, Valerio M, Persson B, et al. Guidelines for perioperative care after radical cystectomy for bladder cancer: enhanced Recovery After Surgery (ERAS((R))) society recommendations. Clin Nutr. Dec 2013;32(6):879-887.

• 9. Khan S GM, Horgan A, Anderson I, MacFie J. Guidelines for Implementation of Enhanced Recovery Protocols. Issues in Professional Practice, Assocation of Surgeons and Great Britain and Ireland 2009; www.asgbi.org.uk/download.cfm?docid=BE0B52EE-AE0E-42C1...

• 10. Miller KR, Wischmeyer PE, Taylor B, McClave SA. An evidence-based approach to perioperative nutrition support in the elective surgery patient. JPEN J Parenter Enteral Nutr. Sep 2013;37(5 Suppl):39S-50S.

• 11. Blom RL, van Heijl M, Bemelman WA, et al. Initial experiences of an enhanced recovery protocol in esophageal surgery. World J Surg. Oct 2013;37(10):2372-2378.

• 12. Bianchini C, Pelucchi S, Pastore A, Feo CV, Ciorba A. Enhanced recovery after surgery (ERAS) strategies: possible advantages also for head and neck surgery patients? Eur Arch Otorhinolaryngol. Mar 2014;271(3):439-443.

• 13. Wong-Lun-Hing EM, van Dam RM, Heijnen LA, et al. Is current perioperative practice in hepatic surgery based on enhanced recovery after surgery (ERAS) principles? World J Surg. May 2014;38(5):1127-1140.

Page 29: Pre “Rehab” Nutrition Beth Hall RD, CSO, LN Billings Clinic 2014

References• 14. Sahoo MR, Gowda MS, Kumar AT. Early rehabilitation after surgery program versus conventional care during

perioperative period in patients undergoing laparoscopic assisted total gastrectomy. J Minim Access Surg. Jul 2014;10(3):132-138.

• 15. Wijk L, Franzen K, Ljungqvist O, Nilsson K. Implementing a structured Enhanced Recovery After Surgery (ERAS) protocol reduces length of stay after abdominal hysterectomy. Acta Obstet Gynecol Scand. May 14 2014.

• 16. de Groot JJ, van Es LE, Maessen JM, Dejong CH, Kruitwagen RF, Slangen BF. Diffusion of Enhanced Recovery principles in gynecologic oncology surgery: Is active implementation still necessary? Gynecol Oncol. Jun 28 2014.

• 17. Lassen K, Coolsen MM, Slim K, et al. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS(R)) Society recommendations. World J Surg. Feb 2013;37(2):240-258.

• 18. Coolsen MM, van Dam RM, van der Wilt AA, Slim K, Lassen K, Dejong CH. Systematic review and meta-analysis of enhanced recovery after pancreatic surgery with particular emphasis on pancreaticoduodenectomies. World J Surg. Aug 2013;37(8):1909-1918.

• 19. Waisbren E, Rosen H, Bader AM, Lipsitz SR, Rogers SO, Jr., Eriksson E. Percent body fat and prediction of surgical site infection. J Am Coll Surg. Apr 2010;210(4):381-389.

• 20. Amri R, Bordeianou LG, Sylla P, Berger DL. Obesity, outcomes and quality of care: body mass index increases the risk of wound-related complications in colon cancer surgery. Am J Surg. Jan 2014;207(1):17-23.

• 21. Lee J, Allen R, Ashley S, et al. British Dietetic Association evidence-based guidelines for the dietary management of Crohn's disease in adults. J Hum Nutr Diet. Jun 2014;27(3):207-218.

• 22. Sigall-Boneh R, Pfeffer-Gik T, Segal I, Zangen T, Boaz M, Levine A. Partial Enteral Nutrition with a Crohn's Disease Exclusion Diet Is Effective for Induction of Remission in Children and Young Adults with Crohn's Disease. Inflamm Bowel Dis. Jun 30 2014.

• 23. Zator ZA, Cantu SM, Konijeti GG, et al. Pretreatment 25-Hydroxyvitamin D Levels and Durability of Anti–Tumor Necrosis Factor–α Therapy in Inflammatory Bowel Diseases. Journal of Parenteral and Enteral Nutrition. March 1, 2014 2014;38(3):385-391.

• 24. Basson A. Vitamin D and Crohn’s Disease in the Adult Patient: A Review. Journal of Parenteral and Enteral Nutrition. May 1, 2014 2014;38(4):438-458.

• 25. Vagianos K, Bector S, McConnell J, Bernstein CN. Nutrition Assessment of Patients With Inflammatory Bowel Disease. Journal of Parenteral and Enteral Nutrition. July 1, 2007 2007;31(4):311-319.

• 26. Naik A NV. Nutritional Care in Adult Inflammatory Bowel Disease. Nutrition Issues in Gastroenterology. 2012(106):18-27.