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    Infectious Disease and Prevention in

    the Perioperative Environment

    This presentation is property of PREZIO Health and may not be used without expressed written permission

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    Program Content:

    Infection prevention in the perioperative

    environment

    Common infectious diseases

    The Chain of Infection

    Six Factors in Disease Transmission

    Standard Precautions

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    TRUE STORY1

    Lisa Black- 26 year old nurse, accidentally

    stuck herself with a contaminated needle

    from a patient in the terminal stages of AIDS.

    Lisa followed all protocols, including ER

    treatment with PEP (post-exposure

    prophylaxis)

    Lisa confirmed HIV and Hep C infectionsseveral months after incident

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    Introduction

    We understand as healthcare professionalswe are at risk for potential exposure topathogenic microorganisms while in ourclinical environment.

    We also understand our actions can placepatients at risk for potential exposure topathogenic microorganisms.

    In this education program, we will examinesome of the common pathogens and reviewmethods to control their spread and protectourselves and patients from exposure

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    Overview of Infectious Diseases

    Infectious diseases are caused by pathogenicmicroorganisms, such as bacteria, viruses,parasites or fungi; the diseases can be spread,directly or indirectly, from one person to another

    Some pathogenic microorganisms included:

    MRSA, VRE, CRE

    Clostridium Difficile C. Diff.

    TB

    Hepatitis B and C

    HIV

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    Standard precaution is an approach toinfection control where all human blood

    and body fluids are treated as if known tobe infectious for blood-borne pathogens.12

    Standard Precaution

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    Chain of Infection

    Pathogenic microorganism

    Mode of transmission

    Susceptible host

    Reservoir Portal of entry

    Six factors of disease transmission and the Chain of Infection2

    Portal of exit

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    Chain of Infection

    Pathogenic

    microorganism

    Six factors of disease transmission and the Chain of Infection2

    Causative agent:

    A microbial organism with the

    ability to cause disease, or apathogenic microorganism

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    BREAK the Chain- Pathogen2

    Prompt Treatment

    Decontamination

    Rapid Identification

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    Chain of Infection

    Reservoir

    Six factors of disease transmission and the Chain of Infection2

    Reservoir:

    The place where the causative

    agent can survive. A human is a

    good example

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    BREAK the Chain- Reservoir2

    Health/Hygiene

    Sanitation

    Disinfection/Sterilization

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    Chain of Infection

    Portal of exit

    Six factors of disease transmission and the Chain of Infection2

    Portal of exit:

    Path by which the pathogen

    leaves the reservoir. Hands,

    clothes, shoes and skin areexamples

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    BREAK the Chain- Portal of Exit2

    Proper attire

    Hand Hygiene

    Proper waste disposal Control of secretions/excretions

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    Chain of Infection

    Mode of transmission

    Six factors of disease transmission and the Chain of Infection2

    Mode of transmission:

    Method of transfer by which the

    organism moves or is carriedfrom one place to another. This

    can be direct or indirect contact

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    BREAK the Chain- Transmission2

    Hand Hygiene

    Airflow control

    Disinfection/Sterilization

    Proper food handling Isolation precautions

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    Chain of Infection

    Portal of entry

    Six factors of disease transmission and the Chain of Infection2

    Portal of exit/Portal of entry:

    Paths by which the pathogen

    leaves the reservoir and enters the

    host. The mucous membranes are

    an example

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    BREAK the Chain- Portal of Entry2

    Aseptic technique

    Wound care

    Hand Hygiene Device care

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    Chain of Infection

    Susceptible host

    Six factors of disease transmission and the Chain of Infection2

    Susceptible host:A person who cannot resist a

    microorganism invading the body

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    BREAK the Chain- Susceptible Host2

    Treatment of disease

    Recognize high risk patients

    Vaccinations

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    The host is susceptible to disease because they lackimmunity or physical resistance to overcome this

    invasion.

    We as healthcare professionals must play an activerole in disrupting the Chain of Infection.

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    Infectious Diseases Bacteria

    Bacteria live in and on everyone and areessential to basic human life functions asnormal flora

    Normal colonization- aids in digestion and helpskeep other microorganisms in check

    Pathogenic microorganisms can sometimesovercome host defenses and/or becomeresistant to antibiotics making them moredifficult to treat

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    Potentially Pathogenic Bacteria

    Types discussed

    Staphylococcus Aureus: Found on the skin ofroughly 30% of individuals- usually not

    harmful unless injected into a skin wound orlesion

    Enterococci: Normally found in humanintestines and the female genital tract

    Enterobacteriaceae: Normal part of thehuman gut including Klebsiella and E. coli.

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    Common Antibiotics/Antimicrobials

    Methicillin Oxacillin, penicillin and amoxicillin

    Vancomycin

    Frequently given prophylactically to surgicalpatients

    Cephalosporins Ceftriaxone, cefotaxime, ceftazidime

    Carbapenems Doripenem, meropenem, imipenem

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    Infectious Diseases - MRSA

    Methicillin Resistant StaphylococcusAureus (MRSA)3

    Occur most frequently among persons inhospitals and healthcare facilities who haveweakened immune systems

    Can cause potentially life threateningsurgical site infections, bloodstreaminfections or pneumonia (most commonly inhigh risk patients with frequent healthcareexposure)

    Can be spread from hand contact,surfaces, or from open wounds. It can alsobe spread by sharing personal items suchas razors or towels

    Examples of MRSA infection

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    Special Consideration:

    MRSA infections that occur in otherwise

    healthy people who have not been recently

    (within the past year) hospitalized or had a

    medical procedure (such as dialysis,

    surgery, catheters) are known ascommunity-associated (CA)-MRSA

    infections.

    These infections are usually skin

    infections, such as abscesses, boils, andother pus-filled lesions

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    Infectious Diseases MRSA

    Methicillin Resistant Staphylococcus Aureus (MRSA) Prevention3 Keep your hands clean by washing thoroughly with soap and water or using an

    alcohol-based hand sanitizer.

    Keep cuts and scrapes clean and covered with a bandage until healed

    Avoid contact with other people's wounds or bandages

    Avoid sharing personal items such as uniforms and personal protectiveequipment

    Follow standard precautions and use PPE when cleaning and decontaminatinginstrumentation and patient care equipment

    Avoid direct patient contact without PPE

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    Infectious Diseases VRE4

    Vancomycin-resistant enterococci

    Colonization with VRE can occur with nosymptoms

    No treatment needed Symptomatic VRE infections can usually be

    treated with antibiotics other thanVancomycin

    Most commonly spread by contaminatedhands of caregivers

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    Infectious Diseases VRE

    What factors put people at risk of infection4? Hospitalization

    Treatment with Vancomycin or other antibioticsfor an extended time period

    Weakened immune system (AIDS,Chemotherapy, age)

    People who undergo surgical procedures

    Presence of long term medical devices (urinary

    catheters, central IV, etc.) Known colonization of VRE

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    Infectious Diseases- CRE5

    Carbapenem-resistant Enterobacteriaceae

    Also resistant to ALL cephalosporins

    Difficult to treat- resistant to most antibiotictreatments

    Infections are potentially deadly

    Fatal in up to 50% of individuals who acquireinvasive blood stream infection6

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    Infectious Diseases- CRE

    Healthy individuals usually do not get CRE

    Risk factors:

    Recent travel to areas with endemic CRE

    Long term devices (ventilators, catheters, IV)

    Long courses of certain antibiotics

    CRE is a serious threat to public health

    Identification and tracking efforts are currentlyunderway by the CDC

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    Infectious Diseases- C. diff

    Clostridium Difficile (C. Diff.) Infection Control7

    Observe enteric and standard precautions and proper hand-washingtechniques to avoid spreading C. Diff.

    Ensure adequate cleaning and disinfection of environmental surfacesand reusable devices, especially items likely to be contaminated withfeces and surfaces that are touched frequently

    Use an Environmental Protection Agency (EPA)-registered disinfectant

    for environmental surface disinfection with a C. diff kill claim Follow the manufacturers instructions for disinfection of endoscopes

    and other devices

    Perform hand hygiene

    Alcohol-based hand sanitizers are not effective against C. diff and shouldnot be used when caring for a patient on enteric precautions.

    Soap and water is effective when vigorous friction is applied to physicallyremove spores from skin surface

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    Special Consideration:

    Latent TB Infection

    In most people who breathe in TB bacteria and

    become infected, the body is able to fight the bacteria

    to stop them from growing.

    People with latent TB infection:Show a positive reaction to the TB skin or blood test

    Do not feel sick and do not have any symptoms

    Are not infectious and cannot spread TB bacteria to others

    However, if TB bacteria become active in the body and

    multiply, the person will get sick with TB disease

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    Infectious Diseases - TB

    Tuberculosis Infection Control8 ALWAYS follow all hospital protocols when handling/cleaning

    equipment known to be contaminated with TB

    As with any instrument following patient use, ensure it is properlycontained while in transit to decontamination area

    All personnel should wear appropriate PPE, following standard

    precautions, when handling instruments used on patients Initial and ongoing monitored and documented TB training should beadministered

    Annual TB testing should be performed on all facility staff on a regularbasis

    If working DIRECTLY with a patient who has known TB infection, allpersonnel must wear a N-95 TB mask, which must be annually fit-tested to each individual wearer.

    TB face mask is not necessary for cleaning contaminated equipment.

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    Viral Infections

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    Infectious Diseases- Hepatitis

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    Infectious Diseases - Hepatitis

    Hepatitis means inflammation of the liver

    Most common viral strains are A, B and C

    Just because they share a name, strains A

    B and C are nothing alike other than thefact that they attack the patients liver

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    Infectious Disease Hepatitis A 9

    Fecal-Oral transmission Food poisoning usually from contaminated

    seafood

    Sexual transmission

    Blood borne/saliva transmission isuncommon

    Does not cause chronic disease- acute liver

    failure is rare Vaccine exists- Encouraged for high riskindividuals

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    Infectious Disease- Hepatitis B 9

    Incubation period = 6 weeks 6 months

    Highest concentration found in blood Pathogen can be transmitted through blood or other bodily

    fluids

    Leading risk factors include: IV drug use

    unprotected sex with multiple partners

    birth to an infected mother

    Can lead to chronic liver infection

    Vaccination series available and recommended for allhealthcare workers

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    Infectious Disease Hepatitis C 9

    Most common chronic blood borne infectionin the US

    Chronic disease develops in 70-85% of

    infected individuals (very high) Most common mode of transmission is

    through blood exposure (IV drug use, needle-sticks, donor blood)

    Can also be transmitted sexually, although muchless common

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    Infectious Disease Hepatitis

    No cures exist for any Hepatitis infection

    Prevention is the key

    Avoidance of high-risk behavior Standard Precautions

    Proper handling of all potentially

    contaminated waste

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    Infectious Disease- HIV 10

    HIV (human immunodeficiency virus) causes

    flu-like symptoms upon initial infection, but

    cannot be cleared out of your body by your

    immune system like most other viruses

    Virus attacks immune cells and destroys

    them, preventing the patients immunesystem from fighting infection

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    Infectious Disease- HIV 10

    HIV cannot replicate outside of the body

    Blood to blood transmission is the most

    common mode

    Infected needles

    High risk sexual activity

    Cannot be transmitted through saliva, skin or

    air contact

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    Infectious Disease- HIV to AIDS

    AIDS (acquired immuno deficiencysyndrome) 10

    Final stage of HIV infection

    Characterized and diagnosed by low immunecell blood counts, certain cancers and/orpresence of opportunistic infection (OI)

    AIDS prevents immune system from fighting

    off disease OI or Cancer kills the patient- not AIDS itself.

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    Infectious Disease- HIV/AIDS

    Prevention is extremely important Standard Precautions

    Avoidance of high risk behavior

    Infected individuals can be treated withmedications that can significantly prolongonset of AIDS from HIV10

    Potentially infected people can seek Post

    Exposure Prophalyxis (PEP) within 24 hoursof exposure Most effective within 2 hours of exposure

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    Influenza

    Influenza (the flu) is a contagious respiratory illness caused by influenza viruses

    It can cause mild to severe illness, and at times can lead to death.

    The best way to prevent the flu is by getting a flu vaccination each year.

    Every year in the United States, on average 5% to 20% of the population gets

    the flu

    More than 200,000 people are hospitalized from flu complications, and about

    36,000 people die from flu-related causes each year

    Some people, such as older people, young children, and people with certain

    health conditions are at high risk for serious flu complications11

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    Influenza Infection Control11

    Routine cleaning and disinfection strategies are used during influenza

    season Management of laundry, utensils and medical waste should also be

    performed in accordance with procedures followed for seasonalinfluenza

    Clean surfaces that have been contaminated with body substances;perform low- to intermediate-level disinfection on cleaned surfaces with

    an EPA-registered disinfectant in accordance with the manufacturer'sinstructions

    Wear PPE appropriate for a surface decontamination and cleaning taskand dispose of using routine procedures

    Decontaminate reusable PPE as appropriate

    In direct patient care environments, employees should take droplet

    precautions through the use of a simple surgical mask (always refer tohospital policy)

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    Summary

    Remember:You, the healthcare professional, have a direct impact in the health and well

    being of the patient.

    Your diligence throughout the healthcare environment will help to ensure patient

    safety and prevent the spread of infectious diseases.

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    References

    1. American Nurses Association. (2002). Needlestick Prevention Guide. Retrieved fromhttp://www.who.int/occupational_health/activities/2needguid.pdf .

    2. IAHCSMM. (2007). CRCST Training Manual(7th edition). 59-76.

    3. Methicillin-resistant Staphylopcoccus Aureus (MRSA) Infections. (2011). Retrieved February 22, 2013,from http://www.cdc.gov/mrsa/#

    4. Vancomycin-resistant Enterococci (CRE) in Healthcare Settings. (2011). Retrieved March 12, 2013,from http://www.cdc.gov/HAI/organisms/vre/vre.html

    5. Carbapenem-resistant Enterobacteriaceae (CRE). (2013). Retrieved March 12, 2013, from

    http://www.cdc.gov/HAI/organisms/cre/ 6. Making Health Care Safer- Stop Infections from Lethal CRE Germs Now. (2013). Retrieved March 12,

    2013, from http://www.cdc.gov/vitalsigns/HAI/CRE/index.html

    7. Clostridium difficile Infection. (2013). Retrieved February 22, 2013, fromhttp://www.cdc.gov/HAI/organisms/cdiff/Cdiff_infect.html

    8. Tuberculosis (TB). (2013). Retrieved February 22, 2013, from http://www.cdc.gov/tb/

    9. Viral Hepatitis. (2013). Retrieved February 22, 2013, from http://www.cdc.gov/hepatitis/

    10. HIV/AIDS. (2013). Retrieved February 22, 2013 from http://www.cdc.gov/hiv/

    11. Seasonal Flu (Influenza). Retrieved February 22, 2013 from http://www.cdc.gov/flu/

    12. Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in HealthcareSettings. (2007). Retrieved March 11, 2012 fromhttp://www.cdc.gov/hicpac/2007IP/2007isolationPrecautions.html

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    Thank You