radiation characteristics of a gated fibre-optic-coupled...
TRANSCRIPT
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Radiation Characteristics of a Gated Fibre-Optic-Coupled Detector
• Chester Reft• University Of Chicago• Department of Radiation and Cellular Oncology
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Purpose: to study some dosimetriccharacteristics of a gated fibre-optic-coupled
detector
Energy dependence for 6 and 18 MV photons, orthovoltage
Energy dependence for 6 20 MeV electrons
Dose linearity
Dose rate response
Reproducibility
Small field dosimetry
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Radioluminescence is the phenomenon by which luminescence is produced in a material by ionizing radiation
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Prompt luminescence exhibited by all glasses
Incident native impuritiesluminescene
radiation defects
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Mechanisms for Irradiation-induced Luminescence in Materials
recombination of EHPs created by irradiation
transient or permanent defects produced by radiation and subsequently serve as recombination centers for mobile electrons or holes
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Features of Optical Fibre Radiation Dosimeters
in-situ, real time dose or accumulated dose measurementswide dynamic range – 10-5 4x103 Gysmall sizerelatively isotropic responsesmall energy dependence for megavoltage γ and e-
all optical no electromagnetic interferenceminimal environmental effects
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Potential Radiation Therapy Applications
In-vivo, real time patient dose monitoring3DCRTIMRT (?)
Small field dosimetry
Fluoroscopic procedures (skin dose)
CT or PET procedures
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The detector is a transparent fused-quartz glass
doped with Cu+1 ions
~ 1 mm long and 400 μm diameter
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Comparison of Detectors
0.330.451.0sens vol th(mm)
3.6x1010
e-/Gy3.3x1010
e-/Gy5x105
cts/Gysens 60Co
2.52.40.4diameter(mm)
4.35.00.13sen area (mm2)
2.622.332.2ρ(g/cm3)
61410.8Z
DiamondDiodeFiberCu1+ silica
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Optical fiber Detector Assembly
Irradiation
Detector Optical Fiber
native fluorescence+
Cerenkov
+phosphorescence
native fluorescence
+
Cerenkov
Gating
Phosphorescence from detector
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B.L. Justus et al.Applied Optics 43 (2004)
X-rays irradiate Cu1+ detector and segment of optical fibreOptical fibre coupled to photon counting moduleAccelerator trigger pulses synchronized with the current serves as a gate
measures the duration of each gate pulse measures the interval between pulses
Data from the counters are buffered and then analyzed
Schematic diagram of the electronics
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B.L. Justus et al.Applied Optics 43 (2004)
Luminescence decay of the Cu1+ emission following pulsed excitation (solid curve)Also shown is the 8 μs wide accelerator trigger pulse (dashed curve)
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SW Phantom
100 cm
Fixed Collimator
Adjustable Collimator
Target
FlatteningFilter
Figure Schematic diagram of experimental set-up showing NRL detector and monitor detector
NRL detectorTo electronics
NRL monitorTo electronics
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1.02020 MeV1.00616 MeV0.99812 MeV0.9769 MeV0.9506 MeV0.99318 MV1.0006 MV
Q(Energy)/Q(6 MV)Energy
Detector energy response normalized to 6 MV photons
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Mass Energy Absorption Coefficient of water to Si Dioxide
0.96
0.98
1
1.02
1.04
1.06
1.08
1.1
1.12
0 2 4 6 8 10 12
Energy (MeV)
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[(μen/ρ)watSiO]18MV
6MV = 0.97
(R/D)6MV18MV ≈ [(μen/ρ)wat
SiO]18MV6MV
1.01 ≈ 0.97
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Mass Stoping Power Ratio of water to pyrex
1.04
1.06
1.08
1.1
1.12
1.14
1.16
1.18
1.2
1.22
0 5 10 15 20 25
E (MeV)
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[(S/ρ)watSiO]6 MeV
20MeV = 1.07
[(R/D)]20MeV6MeV ≈ [(S/ρ)wat
SiO]6MeV20MeV
1.07 ≈ 1.07
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NRL Detector Linearity
-
2.00
4.00
6.00
8.00
10.00
12.00
14.00
- 2.00 4.00 6.00 8.00 10.00 12.00 14.00Dose (Gy)
NR
L si
gnal
nor
mal
ized
to 1
G
6 MV18 MV12 MeVr = 0.99999Linear (6 MV)
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Deliver 50 MU at a depth of 10 cm for a 10x10 cm2 fieldnormalized to 100 MU/min
1.00 ± .020.96 ± .02600
1.001.00 100
18 MV6 MVMU / min
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Detector variation with dose rate relative to the Farmer chamber
0.96
0.97
0.98
0.99
1
1.01
1.02
1.03
1.04
1.05
0 2 4 6 8 10 12Dose Rate
Q(N
RL
) / Q
(Far
mer
18 MV
6 MV
Linear <6 & 18 MV>
Linear (Linear <6 & 18 MV>)
0.33 0.67 1.0
Gy/minmGy/pulse
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P.W. Hoban et al.PMB 39 (1994)
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Detector Reproducibility
± 0.3 %± 0.5 %± 1.0 %± 1.5 %
Ion chamberdiodediamondOptical Fiber
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0.6460.6540.647
0.5150.5240.505
0.6300.6450.632
0.5060.4990.493
0.6280.6250.621
0.4910.4730.479
25DiodeNRLDiam
0.7480.7530.748
0.6420.6470.632
0.7340.7230.733
0.6340.6240.622
0.7480.7010.723
0.6230.6240.611
20DiodeNRLDiam
.08650.8690.865
0.8010.8110.796
0.8580.8540.858
0.7980.7650.792
0.8790.8630.851
0.7900.8020.780
15DiodeNRLDiam
1.0001.0001.0001.0001.0001.00010
DiodeNRLDiam
1.1431.1301.138
1.2481.2771.250
1.1721.1491.159
1.2741.2811.261
1.1771.2011.168
1.2211.2921.278
5DiodeNRLDiam
18X6X18X6X18X6X
2.0x2.01.0x1.00.6x0.6d(cm)
Small field TPR measurements with detectors
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1.20.2
0.70
0.50
-1.1-0.4
18 MV
2.40.3
-1.5-0.1
-0.50
-1.9-1.1
18 MV
-0.5-1.1
-6.3-3.3
-1.8-3.2
2.0-0.8
18 MV
1.7-1.9
-1.4-2.6
-3.7-2.4
25 – NRL- Diam
0.7-1.5
-1.6-1.9
0.2-1.9
20 – NRL- Diam
1.2-0.6
-4.1-0.8
1.5-1.3
15 - NRL- Diam
1.10.2
0.5-1.0
5.84.7
5 - NRL- Diam
6 MV6 MV6 MV
2.0x2.01.0x1.00.6x0.6d(cm) - det
% difference of small field TPR measurements with NRL and diamond detectors relative to diode detector
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0.992 ± .0120.991 ± .018Diamond
0.994 ± .0221.000 ± .025NRL
18 MV6 MV
Averaged ratio of TPR measurements with NRL and diamond detectors relative to the diode detector
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Future work
Modify the software to allow measurements for orthovoltage radiation
Therapy
Diagnostic
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1.003.60110250 kVp1mm Cu
1.113.9992200 kVp1.0mm Cu
1.435.1464200 kVp.2mm Cu
1.686.0457150 kVp0.2mm Cu
1.977.0936125 kVpNo filter
<cts>/cGyNorm 110KeV
<cts>/cGy<E0>KeV
Quality
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Mass Energy Absorption Coefficient of water to silicon dioxide
0
0.2
0.4
0.6
0.8
1
1.2
0 50 100 150 200 250 300 350 400 450Energy (KeV)
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0.8010.02590.0323110
0.2560.1040.40736
(μen/ρ)watSiO(μen/ρ)wat(μen/ρ)SiOE(KeV)
[(μen / ρ)]110kVp36kVp = 3.13
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[(μen/ρ)watSiO]110KeV
36KeV = 3.13
(R/D)36KeV110KeV ≈ [(μen/ρ)wat
pyr]110KeV36KeV
1.97 ≈ 3.13
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Conclusions
• Favorable Dosimetric properties compared to other detectors
– Energy response• Megavoltage – small variation• Orthovoltage – large variation
– Linearity– Dose Rate– Reproducibility
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•Small size ideal for small field dosimetry such as stereotactic radiosurgery
•Small size and optical interface make them potentially useful for in-vivo dosimetry
Conclusions Continued
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