report of president 2011/2012 - conway institute · 2020. 7. 17. · report of president 2011/2012...

Report of President 2011/2012 - Conway

Institute

>> Book Chapters

>> Books Edited

>> Peer Reviewed Journals

>> Other Journals

>> Conference Publications

>> Other Publications

Book Chapters

Professor Alan Baird

Rathbone MJ & McDowell A (2012) 'Human/Veterinary technology crossover' In: Long

acting animal health drug products. NY. London, Heidelberg: Springer.

Dr John Andrew Baugh

Li L. and Baugh JA (2012) 'Regulation of MIF Gene Expression in the Lung' In:

Richard Bucala (eds). The MIF Handbook. Singapore: World Scientific Publishing.

Professor David Brayden

Maher, S., Ryan, K. B., Ahmad, T., O'Driscoll, C. M. & Brayden, D. J. (2012)

'Nanostructures overcoming the intestinal barrier: physiological considerations and

mechanistic issues' In: Alonso, MJ & Csaba, N (eds). Nanostructured biomaterials for

overcoming biological barriers. London: Royal Society of Chemisty.

Ryan, K. B., Maher, S., Ahmad, T., Brayden, D. J. & C.M. ODriscoll (2012)

'Nanostructures overcoming the intestinal barrier: drug delivery strategies' In: Alonso,

MJ & Csaba, N (eds). Nanostructured biomaterials for overcoming biological barriers.

London: Royal Society of Chemistry.

Professor Geraldine Butler

Butler G, Lorenz M, Gow NAR (2012) 'Evolution and genomics of the pathogenic

Candida species complex' In: L. David Sibley, Barbara J. Howlett, Joseph Heitman

(eds). Evolution of Virulence in Eukaryotic Microbes. New Jersey: Wiley-Blackwell.

Butler, G; (2012) 'Comparative genomics of Candida species' In: Candida and

Candidiasis, 2nd edition. Washington, DC: ASM Press.

Dr Gerard Cagney

Ryan C, Cagney G, Krogan NJ, Cunningham P, Greene D (2011) ''Imputing and

predicting quantitative genetic interactions in epistatic MAPs' In: Network Biology:

Methods and Applications (Methods in Molecular Biology). USA: Springer Verlag.

Professor Sean Callanan

Fletcher NF, Callanan JJ (2012) 'Cell Culture Models of the Blood-Brain Barrier: New

Research' In: The Blood Brain Barrier: New Research. NOVA SCIENCE

PUBLISHERS New York: NOVA SCIENCE PUBLISHERS.

https://rms.ucd.ie/ufrs/[email protected]






http://www.springerprotocols.com/Abstract/doi/10.1007/978-1-61779-276-2_17

Professor Patrick Guiry

Grainne C. Hargaden and Patrick J. Guiry (2012) 'Development of the Asymmetric

Nozaki-Hiyama-Kishi Reaction' In: Pher G. Andersson (eds). Innovative Catalysis in

Organic Synthesis. Weinheim, Germany: Wiley-VCH.

Dr Tara McMorrow

O'Connell S, Nolan S, Slattery C, Ryan MP, McMorrow T. (2012) 'The role of

Transglumatinase in Kidney Disease' In: Fibronectin and Disease. Croatia: Intech.

Slattery C, Cassidy H, Johnston O, Ryan MP and McMorrow T (2012) 'Mechanisms of

calcineurin inhibitor nephrotoxicity in chronic allograft injury' In: Chronic Kidney

Disease and Renal Transplantation. India: Research Signpost.

Dr Anika Mostaert

Jarvis, S.P. and Mostaert, A.S. (2012) 'The fine line between pathology and physiology'

In: Jarvis, S.P. and Mostaert, A.S (eds). The Functional Fold. Amyloid Structures in

Nature. Singapore: Pan Stanford Publishing.

Mostaert, A.S. and Jarvis, S.P. (2012) 'Functional amyloid in natural adhesives' In:

Jarvis, S.P. and Mostaert, A.S (eds). The Functional Fold. Amyloid Structures in Nature.

Singapore: Pan Stanford Publishing.

Brennan, L., Mostaert, A.S., Murphy, C. and Owende, P. (2012) 'Phytochemicals from

Algae' In: Carrier, J., Ramaswamy, S. and Bergeron, C (eds). Biorefinery Co-Products:

Phytochemicals, Primary Metabolites and Value-Added Biomass Processing.

Chichester, West Sussex, UK: John Wiley & Sons.

Dr Keith Murphy

O'Sullivan NC, Sheridan GK, Murphy KJ; (2012) 'Transcriptional profiling of

hippocampal memory-associated synaptic plasticity: Old friends and new faces' In:

Transcription Factors CREB and NF-κB: Involvement in Synaptic Plasticity and

Memory Formation. E-Book: Bentham.

Professor William Powderly

Powderly WG (2012) 'Candida in HIV infection' In: P Volberding, J Lange, W Greene, J

Gallant, NK Sewankambo (eds). Sande's HIV/AIDS Medicine: Medical Management of

AIDS. Baltimore: Elsevier.

Dr Emma C Teeling

Teeling, E.C., Dool, S. and Springer, M.S. (2012) 'Phylogenies, fossils and functional

genes: The evolution of echolocation in bats' In: Gunnell, G.F. and Simmons, N.B (eds).

Evolutionary History of Bats: Fossils, Molecules, and Morphology. Cambridge:

Cambridge University Press.

Back to Top

Books Edited

Dr Gerard Cagney

Cagney G, and Emili A (Ed.). (2011) Network Biology: Methods and Applications (Methods

in Molecular Biology). New York London:: Springer.








http://www.panstanford.com/books/9789814267403.html


http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0470973579.html

Dr Chandralal Hewage

Hewage C (Ed.). (2012) EUROMAR 2012. Keynote Dublin: Keynote.

Dr Anika Mostaert

Jarvis, S.P. and Mostaert, A.S (Ed.). (2012) The Functional Fold. Amyloid Structures in

Nature. Singapore: Pan Stanford Publishing.

Back to Top

Peer Reviewed Journals

Professor Mohamed Al-Rubeai

Lahoti, Varun; Murphy, William; Al-Rubeai, Mohamed (2012) 'Mathematical

approach for the optimal expansion of erythroid progenitors in monolayer culture'.

Journal of Biotechnology, 161 (3).

Tan F., O'Neill F., Naciri M., Dowling D., Al-Rubeai M. (2012) 'Cellular and

transcriptomic analysis of human mesenchymal stem cell response to plasma-

activated hydroxyaptite coating'. Acta biomaterialia .

Tan F., Naciri M., Dowling D., Al-Rubeai M. (2012) 'In Vitro and In Vivo

Bioactivity of CoBlast Hydroxyapatite Coating and the Effect of Impaction on its

Osteoconductivity'. Biotechnology Advances .

Kuystermans, Darrin; Mohd, Avesh; Al-Rubeai, Mohamed (2012) 'Automated

flow cytometry for monitoring CHO cell cultures'. Methods, 56 (3):358-365.

Kuystermans, Darrin; Al-Rubeai, Mohamed (2012) 'Current advances in

applications of cell culture Introduction'. Methods, 56 (3):335-337.

Browne, S.M. and Al-Rubeai, M. (2011) 'Defining viability in mammalian cell

cultures'. Biotechnology Letters, 33 (9):1745-1749.

Professor Alan Baird

Mohan HM, Aherne CM, Rogers AC, Baird AW, Winter DC, Murphy EP. (2012)

'The role of NR4A orphan nuclear receptors in cancer'. Clinical Cancer Research,

18 (12):3223-3228.

Bzik, V., Medani, M., Baird, A. W., Winter, D., Brayden, D.J. (2012)

'Mechanisms of Action of Zinc on Intestinal Epithelial Electrogenic Ion Secretion:

Insights into its Anti-Diarrheal Actions'. Journal of Pharmacy and Pharmacology,

64 (5):644-653.

Bzik VA, Medani M, Baird AW, Winter DC, Brayden DJ (2012) 'Mechanisms of

action of zinc on rat intestinal epithelial electrogenic ion secretion: insights into its

antidiarrhoeal actions'. The Journal of pharmacy and pharmacology, 64 (5):644-

653.

Morrissey PEW; Folan, MA; Fijalkowski, K.; Baird, AW; Irwin, JA (2012)

'Inhibition of Streptococcus mutans binding to hydroxylapatite using partially

digested whey protein concentrate and individual whey proteins'. Journal of

Functional Foods, 4 (2):559-567.

Dr John Andrew Baugh

Robinson CM, Neary R, Levendale A, Watson CJ, Baugh JA (2012) 'Hypoxia-

induced dna hypermethylation in human pulmonary fibroblasts is ssociated with







thy-1 promoter methylation and the development of a pro-fibrotic Phenotype'.

Respiratory research, 13 (1).

Adamali H, Armstrong ME, McLaughlin AM, Cooke G, McKone E, Costello

CM, Gallagher CG, Leng L, Baugh JA, Fingerle-Rowson G, Bucala RJ,

McLoughlin P, Donnelly SC (2012) 'Macrophage migration inhibitory factor

enzymatic activity, lung inflammation, and cystic fibrosis'. Critical Care

Medicine, 186 (2):162-169.

Watson CJ, Phelan D, Xu M, Collier P, Neary R, Smolenski A, Ledwidge M,

McDonald K, Baugh J (2012) 'Mechanical stretch up-regulates the B-type

natriuretic peptide system in human cardiac fibroblasts: a possible defense against

transforming growth factor-β mediated fibrosis'. Gene, 5 (1).

Collier P, Watson CJ, van Es MH, Phelan D, McGorrian C, Tolan M, Ledwidge

MT, McDonald KM, Baugh JA (2012) 'Getting to the heart of cardiac remodeling;

how collagen subtypes may contribute to phenotype'. Journal of Molecular and

Cellular Cardiology, 52 (1):148-153.

Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J,

Watson C, O'Loughlin C, Ledwidge M (2012) 'Long-term statin therapy in

patients with systolic heart failure and normal cholesterol: effects on elevated

serum markers of collagen turnover, inflammation, and B-type natriuretic peptide'.

Clinical therapeutics, 34 (1):91-100.

Dr Orina Belton

Mooney D, McCarthy C, Belton O (2012) 'Effects of conjugated linoleic acid

isomers on monocyte, macrophage and foam cell phenotype in atherosclerosis'.

Prostaglandins & other lipid mediators, 98 (3-4):56-62.

Reynolds CM, Toomey S, McBride R, McMonagle J, Morine MJ, Belton O,

Moloney AP, Roche HM (2012) 'Divergent effects of a CLA-enriched beef diet on

metabolic health in ApoE(-/-) and ob/ob mice'. Journal of Nutritional

Biochemistry, Epub ahead of print .

Duffy MM, Pindjakova J, Hanley SA, McCarthy C, Weidhofer GA, Sweeney EM,

English K, Shaw G, Murphy JM, Barry FP, Mahon BP, Belton O, Ceredig R,

Griffin MD; (2011) 'Mesenchymal stem cell inhibition of T-helper 17 cell-

differentiation is triggered by cell-cell contact and mediated by prostaglandin E2

via the EP4 receptor'. J IMMUNOL, 41 (10):2840-2851.

Dr Oliver Blacque

Radford R, Slattery C, Jennings P, Blaque O, Pfaller W, Gmuender H, Van Delft

J, Ryan MP, McMorrow T. (2012) 'Carcinogens induce loss of the primary cilium

in human renal proximal tubular epithelial cells independently of effects on the

cell cycle'. American Journal of Physiology-Renal Physiology, 302 (8):905-916.

Kaplan OI, Doroquez DB, Cevik S, Bowie RV, Clarke L, Sanders AAWM, Kida

K, Rappoport JZ, Sengupta P and Blacque OE (2012) 'Endocytosis Genes

Facilitate Protein and Membrane Transport in C. elegans Sensory Cilia'. Current

Biology, 22 (6):451-460.

Reynolds AL, Blacque OE, Kennedy BN. (2012) 'The genetics of outer segment

morphogenesis in zebrafish'. Advances in Experimental Medical Biology, 723

:431-441.

Reiter JF, Blacque OE, Leroux MR. (2012) 'The base of the cilium: roles for



http://www.springerlink.com/content/r42924w780515p11/?MUD=MP

transition fibres and the transition zone in ciliary formation, maintenance and

compartmentalization'. Embo Reports, 13 (7):608-618.

Huang L, Szymanska K, Jensen VL, Janecke AR, Innes AM, Davis EE, Frosk P,

Li C, Willer JR, Chodirker BN, Greenberg CR, McLeod DR, Bernier FP, Chudley

AE, Muller T, Shboul M, Logan CV, Loucks CM, Beaulieu CL, Bowie RV, Bell

SM, Adkins J, Zuniga FI, Ross KD, Wang J, Ban MR, Becker C, Nurnberg P,

Douglas S, Craft CM, Akimenko MA, Hegele RA, Ober C, Utermann G, Bolz HJ,

Bulman DE, Katsanis N, Blacque OE, Doherty D, Parboosingh JS, Leroux MR,

Johnson CA, Boycott KM. (2011) 'TMEM237 is mutated in individuals with a

Joubert syndrome related disorder and expands the role of the TMEM family at

the ciliary transition zone'. American Journal of Human Genetics, 89 (6):713-730.

Professor Billy Bourke

Drumm BR, Bourke B, Drummond J, McNicholas F, Quinn S, Broderick A,

Taaffe S, Twomey J, Rowland M (2012) 'Cyclic vomiting syndrome in children:A

prospective study'. Neurogastroenterology and Motility .

Casey JP, McGettigan P, Lynam-Lennon N, McDermott M, Regan R, Conroy J,

Bourke B, Sullivan JO, Crushell E, Lynch S, Ennis S (2012) 'Identification of a

mutation in LARS as a novel cause of infantile hepatopathy'. Molecular Genetics

and Metabolism, 106 (3):351-358.

Blackburn C, McDermott M, Bourke B (2012) 'Clinical presentation of and

outcome for solitary rectal ulcer syndrome in children'. Journal of Pediatric

Gastroenterology and Nutrition, 54 (2):263-265.

Hope B, Shahdadpuri R, Dunne C, Broderick AM, Grant T, Hamzawi M,

O'Driscoll K, Quinn S, Hussey S, Bourke B (2012) 'Rapid rise in incidence of

Irish paediatric inflammatory bowel disease'. Archives of Disease in Childhood,

97 (7):590-594.


Brayden, D.J., Bzik, V., Lewis, A.L. & Illum, L (2012) 'CriticalSorb promotes

permeation of flux markers across isolated rat intestinal mucosae and Caco-2

monolayers'. Pharmaceutical Research .

Bzik, V., Medani, M., Baird, A. W., Winter, D., Brayden, D.J. (2012)

'Mechanisms of Action of Zinc on Intestinal Epithelial Electrogenic Ion Secretion:

Insights into its Anti-Diarrheal Actions'. Journal of Pharmacy and Pharmacology,

64 (5):644-653.

Jones, M., Mantovani, G., Blindauer, C., Wang, X., Ryan, S.M., Brayden, D. J. &

Haddleton, D.M. (2012) 'Direct peptide conjugation at tyrosine with linear and

branched polymeric diazonium salts'. Journal of the American Chemical Society,

134 (17):7406-7413.

Coco, R., Plapied, L., Pourcelle, V., Jérôme, C., Brayden, D,J,, Schneider, Y.J., &

Préat, V. (2012) 'Drug delivery to inflamed colon by nanoparticles: comparison of

different strategies'. International Journal of Pharmaceutics .

Dr Lorraine Brennan

Osorio, M.T., Moloney, A.P., Brennan, L. and Monahan, F.J.; (2012)

'Authentication of beef production systems using a metabolomics based approach'.




http://www.sciencedirect.com/science/article/pii/S0002929711004836

Animal, 6 :167-172.

Morris C, O'Grada C, Ryan M, Roche HM, Gibney MJ, Gibney ER, Brennan L.

(2012) 'The relationship between BMI and metabolomic profiles: a focus on

amino acids'. Proceedings of the Nutrition Society, :1-11.

Claesson MJ, Jeffery IB, Conde S, Power SE, O'Connor EM, Cusack S, Harris

HM, Coakley M, Lakshminarayanan B, O'Sullivan O, Fitzgerald GF, Deane J,

O'Connor M, Harnedy N, O'Connor K, O'Mahony D, van Sinderen D, Wallace M,

Brennan L, Stanton C, Marchesi JR, Fitzgerald AP, Shanahan F, Hill C, Ross RP,

O'Toole PW (2012) 'Gut microbiota composition correlates with diet and health in

the elderly'. Nature, 488 (7410):178-184.

Wallace M, Cottell E, Gibney MJ, McAuliffe FM, Wingfield M, Brennan L

(2012) 'An investigation into the relationship between the metabolic profile of

follicular fluid, oocyte developmental potential, and implantation outcome'.

Fertility and sterility, 97 (5):1078-101.

Ni Raghallaigh S, Bender K, Lacey N, Brennan L, Powell FC (2012) 'The fatty

acid profile of the skin surface lipid layer in papulopustular rosacea'. The British

journal of dermatology, 166 (2):279-287.

Professor Geraldine Butler

Riccombeni1 A, Vidanes1 G, Proux-Wera E, Wolfe KH, Butler G (2012)

'Sequence and analysis of the genome of the pathogenic yeast Candida

orthopsilosis'. PLoS ONE, 7 (e35750).

Guida A, Lindstaedt C, Maguire SL, Ding C, Higgins DG, Corton NJ, Berriman

M, Butler G; (2011) 'Using RNA-seq to determine the transcriptional landscape

and the hypoxic response of the pathogenic yeast Candida parapsilosis'. BMC

Genomics, 12 .

Ding C, Vidanes GM, Maguire SL, Guida A, Synnott JM, Andes DR, Butler G

(2011) 'Conserved and Divergent Roles of Bcr1 and CFEM Proteins in Candida

parapsilosis and Candida albicans'. PLoS ONE, 6 .

Dr Gerard Cagney

Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu

H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, Edelmann W,

Keogh MC, Greene D, Tang C, Cunningham P, Shokat KM, Cagney G, Svensson

JP, Guthrie C, Espenshade PJ, Ideker T, Krogan NJ (2012) 'Hierarchical

Modularity and the Evolution of Genetic Interactomes across Species'. Molecular

cell, 46 (5):691-704.

Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M,

Krogan N, Ren B, Song JS, Reiter JF (2012) 'Polycomb-like 3 promotes polycomb

repressive complex 2 binding to CpG islands and embryonic stem cell self-

renewal'. PLoS Genetics, 8 (3).

Jaeger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC,

Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva

E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue

AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD,

Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS,

Burlingame A, Sali A, Frankel AD, Krogan NJ (2011) 'Global landscape of HIV-

human protein complexes'. Nature, 481 (7381):365-370.



http://dx.doi.org/10.1017/S1751731111001418

Professor Sean Callanan

Zagozdzon AM, O'Leary P, Callanan JJ, Crown J, Gallagher WM, Zagozdzon R.

(2012) 'Generation of a new bioluminescent model for visualisation of mammary

tumour development'. BMC Cancer .

Campbell M, Hanrahan F, Gobbo OL, Kelly ME, Kiang AS, Humphries MM,

Nguyen AT, Ozaki E, Keaney J, Blau CW, Kerskens CM, Cahalan SD, Callanan

JJ, Wallace E, Grant GA, Doherty CP, Humphries P (2012) 'Targeted suppression

of claudin-5 decreases cerebral oedema and improves cognitive outcome

following brain injury'. Nature Communications .

O'Connor, AE McGee MM, Likar Y, Ponomarev V, Callanan JJ, O'Shea DF,

Byrne AT, Gallagher WM (2012) 'Mechanism of Cell Death Mediated by a BF2-

Chelated Tetraarylazadipyrromethene Photodynamic Therapeutic'. International

Journal of Cancer, 130 (3):705-715.

Chapwanya A, Meade KG, Foley C, Narciandi F, Evans AC, Doherty ML,

Callanan JJ, O'Farrelly C. (2012) 'The postpartum endometrial inflammatory

response: a normal physiological event with potential implications for bovine

fertility'. Reproduction Fertility and Development .

Dr Marguerite Clyne

Lane JA, Marino K, Naughton J, Kavanaugh D, Clyne M, Carrington SD, Hickey

RM (2012) 'Anti-infective bovine colostrum oligosaccharides: Campylobacter

jejuni as a case study'. International Journal of Food Microbiology, 157 (2):182-

188.

Backert S, Clyne M, Tegtmeyer N (2011) 'Molecular mechanisms of gastric

epithelial cell adhesion and injection of CagA by Helicobacter pylori'. Cell

Communication and Signaling, 9 :28-35.

Backert S and Clyne M (2011) 'Pathogenesis of Helicobacter pylori infection'.

Helicobacter, 16 (Supplement 1):19-25.

Dr John Crean

O'Donovan HC, Hickey F, Brazil DP, Kavanagh DH, Oliver N, Martin F, Godson

C, Crean J (2012) 'Connective tissue growth factor antagonizes transforming

growth factor-β1/Smad signalling in renal mesangial cells'. Biochem J, 441 :499-

510.

Professor Mark Crowe

Forde N, Duffy GB, McGettigan PA, Browne JA, Mehta JP, Kelly AK, Mansouri-

Attia N, Sandra O, Loftus BJ, Crowe MA, Fair T, Roche JF, Lonergan P, Evans

AC (2012) 'Evidence for an early endometrial response to pregnancy in cattle:

both dependent upon and independent of interferon tau'. Genomics, 44 (16):799-

810.

Walsh SW, Matthews D, Browne JA Forde N, Crowe MA, Mihm M, Diskin MG,

Evans ACO (2012) 'Acute dietary restriction in heifers alters expression of genes

regulating exposure and response to gonadotrophins and IGF in dominant

follicles'. Animal Reproduction Science, 133 (1-2):43-51.

Walsh SW, Mehta JP, McGettigan PA, Browne JA, Forde N, Alibrahim RM,

Mulligan FJ, Loftus B, Crowe MA, Matthews D, Diskin M, Mihm M, Evans AC





http://dx.doi.org/10.1016/j.anireprosci.2012.06.012

(2012) 'Effect of the metabolic environment at key stages of follicle development

in cattle: focus on steroid biosynthesis'. Genomics, 44 (9):504-517.

Aungier, SPM; Roche, JF; Sheehy, M; Crowe, MA (2012) 'Effects of management

and health on the use of activity monitoring for estrus detection in dairy cows'.

Journal of Dairy Science, 95 (5):2452-2466.

Crowe MA, Williams EJ (2012) 'Effects of stress on postpartum reproduction of

dairy cows'. Journal of Animal Science, 90 (5):1772-1727.

Parr MH, Mullen MP, Crowe MA, Roche JF, Lonergan P, Evans AC, Diskin MG

(2012) 'Relationship between pregnancy per artificial insemination and early

luteal concentrations of progesterone and establishment of repeatability estimates

for these traits in Holstein-Friesian heifers'. Journal of Dairy Science, 95

(5):2390-2396.

Mullen MP, Elia G, Hilliard M, Parr MH, Diskin MG, Evans AC, Crowe MA

(2012) 'Proteomic characterization of histotroph during the preimplantation phase

of the estrous cycle in cattle'. Journal of Proteome Research, 11 (5):3004-3018.

Herlihy MM, Crowe MA, Diskin MG, Butler ST (2012) 'Effects of

synchronization treatments on ovarian follicular dynamics, corpus luteum growth,

and circulating steroid hormone concentrations in lactating dairy cows'. Journal of

Dairy Science, 95 (2):743-754.

Mullen MP, Forde N, Parr MH, Diskin MG, Morris DG, Nally JE, Evans AC,

Crowe MA (2012) 'Alterations in systemic concentrations of progesterone during

the early luteal phase affect RBP4 expression in the bovine uterus'. Reproduction,

fertility, and development, 24 (5):715-722.

Gath, VP, Crowe, MA, O'Callaghan, D, Boland, MP, Duffy, P, Lonergan, P,

Mulligan, FJ (2012) 'Effects of diet type on establishment of pregnancy and

embryo development in beef heifers'. Animal Reproduction Science, 133 (3):139-

145.

Earley B, McDonnell B, Murray M, Prendiville DJ and Crowe MA; (2011) 'The

effect of sea transport from Ireland to the Lebanon on inflammatory,

adrenalcortical, metabolic and behavioural responses of bulls'. Research in

Veterinary Science, 91 (3):454-464.

Pluta, K., Irwin, J.A., Dolphin, C., Richardson, L., Fitzpatrick, E., Gallagher,

M.E., Reid, C.J, Crowe, M.A., Roche, J.F., Lonergan, P., Carrington, S.D., Evans,

A,C, (2011) 'Glycoproteins and glycosidases of the cervix during the periestrous

period in cattle'. Journal of Animal Science, 89 (12):4032-4042.

Herlihy, MM,Berry, DP,Crowe, MA,Diskin, MG,Butler, ST; (2011) 'Evaluation

of protocols to synchronize estrus and ovulation in seasonal calving pasture-based

dairy production systems'. Journal of Dairy Science, 94 (9):4488-4501.

Swangchan-Uthai T, Walsh SW, Alexander SL, Cheng Z, Crowe MA, Evans AC,

Wathes DC; (2011) 'Comparison of mRNA for IGFs and their binding proteins in

the oviduct during the peri-oestrous period between dairy heifers and lactating

cows'. Reproduction (Cambridge, England), 142 (3):457-465.

Professor Michael Duffy

Brennan DJ, O'Connor DP, Laursen H, McGee SF, McCarthy S, Zagozdzon R,

Rexhepaj E, Culhane AC, Martin FM, Duffy MJ, Landberg G, Ryden L, Hewitt

SM, Kuhar MJ, Bernards R, Millikan RC, Crown JP, Jirström K, Gallagher WM


(2012) 'The cocaine- and amphetamine-regulated transcript mediates ligand-

independent activation of ERα, and is an independent prognostic factor in node-

negative breast cancer'. Oncogene, 31 (30):3483-3494.

Collins DM, O'Donovan N, McGowan PM, O'Sullivan F, Duffy MJ, Crown J

(2012) 'Trastuzumab induces antibody-dependent cell-mediated cytotoxicity

(ADCC) in HER-2-non-amplified breast cancer cell lines'. Annals of Oncology, 23

(7):1788-1795.

Walsh S, Flanagan L, Quinn C, Evoy D, McDermott EW, Pierce A, Duffy MJ

(2012) 'mTOR in breast cancer: differential expression in triple-negative and non-

triple-negative tumors'. Breast (Edinburgh, Scotland), 21 (2):178-182.

Tryfonopoulos D, Walsh S, Collins DM, Flanagan L, Quinn C, Corkery B,

McDermott EW, Evoy D, Pierce A, O'Donovan N, Crown J, Duffy MJ (2011)

'Src: a potential target for the treatment of triple-negative breast cancer'. Annals of

Oncology, 22 (10):2234-2240.

Dr Giuliano Elia

Jarboui, M.A., Bidoia, C., Roe, B., Wynne, K., Elia, G., Hall, W.A. and Gautier,

V.W. (2012) 'Nucleolar protein trafficking in response to HIV-1 Tat: Rewiring the

nucleolus'. PLoS ONE, 7 (11).

Åkesson, A., Cárdenas, M., Elia, G., Monopoli, M.P. and Dawson, K.A. (2012)

'The Protein Corona of Dendrimers: PAMAM Binds and Activates Complement

Proteins in Human Plasma in a Generation Dependent Manner'. Royal Society of

Chemistry, 2 :11245-11248.

Keenan, J., Manning, G., Elia,G., Dunn, M.J., Orr, D.F., and Pierscionek, B.K.

(2012) 'Crystallin distribution patterns in Litoria infrafrenata and Phyllomedusa

sauvagei lenses'. Proteomics, 12 (11):1830-1843.

Faulkner, S., Elia, G., Mullen, M.P., O'Boyle, P., Dunn, M.J. and Morris, D.

(2012) 'A comparison of the bovine uterine and plasma proteome using iTRAQ

proteomics'. Proteomics, 12 (12):2014-2023.

Elia, G. (2012) 'Cell Surface Protein Biotinylation for SDS-PAGE Analysis'.

Methods in Molecular Biology, 869 :361-372.




Gegenbauer, K., Elia, G., Blanco-Fernandez, A and Smolenski, A.; (2012)

'Regulator of G-protein signaling protein 18 integrates activating and inhibitory

signaling in platelets'. Blood, 119 (16):3799-3807.

Jarboui, M.A., Wynne, K., Elia, G., Hall, W.W. and Gautier, V.W.; (2011)

'Proteomic profiling of the human T-cell nucleolus'. Molecular immunology, 49

(3):441-452.

Martin Lundqvist , Johannes Stigler , Tommy Cedervall , Tord Berggård ,

Michelle B Flanagan , Iseult Lynch , Giuliano Elia , and Kenneth Dawson ; (2011)

'The Evolution of the Protein Corona around Nanoparticles, a Test Study'. ACS

Nano, 5 (9):7503-7509.

Caputo, E., Maiorana, L., Vasta, V., Pezzino, F.M., Sunkara, S., Wynne, K., Elia,

G., Marincola, F.M., McCubrey, J.A., Libra, M., Travali, S. and Kane, M. ; (2011)

'Characterization of human melanoma cell lines and melanocytes by proteome


analysis'. Cell cycle (Georgetown, Tex.), 10 (17):2924-2936.

Professor Paul Engel

Nayla Munawar & Paul C. Engel (2012) 'Overexpression in a non-native halophilic

host and biotechnological potential of NAD+-dependent glutamate dehydrogenase

from Halobacterium salinarum strain NRC-36014'. Extremophiles .

Tânia Oliveira, Santosh Panjikar, John B. Carrigan, Muaawia Hamza, Michael A.

Sharkey, Paul C. Engel and Amir R. Khan (2012) 'Crystal structure of NAD+-

dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals

determinants of cofactor specificity'. Journal of Structural Biology, 177 (2):543-

552.

Engel, P.C. (2011) 'A marriage full of surprises: forty-five years living with

glutamate dehydrogenase'. Neurochemistry International, 59 (4):489-494.

Professor Alexander Evans

Evans AC, Mossa F, Walsh SW, Scheetz D, Jimenez-Krassel F, Ireland JL, Smith

GW, Ireland JJ (2012) 'Effects of maternal environment during gestation on

ovarian folliculogenesis and consequences for fertility in bovine offspring'.

Reproduction in domestic animals = Zuchthygiene, 47 Suppl 4 :31-37.





810.

Cummins SB, Waters SM, Evans AC, Lonergan P, Butler ST (2012) 'Genetic

merit for fertility traits in Holstein cows: III. Hepatic expression of somatotropic

axis genes during pregnancy and lactation'. Journal of Dairy Science, 95 (7):3711-

3721.

Cummins SB, Lonergan P, Evans AC, Butler ST (2012) 'Genetic merit for fertility

traits in Holstein cows: II. Ovarian follicular and corpus luteum dynamics,

reproductive hormones, and estrus behavior'. Journal of Dairy Science, 95

(7):3698-3710.

Hutchinson IA, Hennessy AA, Waters SM, Dewhurst RJ, Evans AC, Lonergan P,

Butler ST (2012) 'Effect of supplementation with different fat sources on the

mechanisms involved in reproductive performance in lactating dairy cattle'.

Theriogenology, 78 (1):12-27.

Walsh SW, Matthews D, Browne JA, Forde N, Crowe MA, Mihm M, Diskin M,

Evans AC (2012) 'Acute dietary restriction in heifers alters expression of genes

regulating exposure and response to gonadotrophins and IGF in dominant

follicles'. Animal Reproduction Science, 133 (1-2):43-51.

Walsh SW, Mehta JP, McGettigan PA, Browne JA, Forde N, Alibrahim RM,

Mulligan FJ, Loftus B, Crowe MA, Matthews D, Diskin M, Mihm M, Evans AC

(2012) 'Effect of the metabolic environment at key stages of follicle development

in cattle: focus on steroid biosynthesis'. Genomics, 44 (9):504-517.

Mossa F, Walsh SW, Butler ST, Berry DP, Carter F, Lonergan P, Smith GW,

Ireland JJ, Evans AC (2012) 'Low numbers of ovarian follicles 3 mm in

diameter are associated with low fertility in dairy cows'. Journal of Dairy Science,

95 (5):2355-2361.









(5):2390-2396.

Hutchinson IA, Hennessy AA, Dewhurst RJ, Evans AC, Lonergan P, Butler ST

(2012) 'The effect of strategic supplementation with trans-10,cis-12 conjugated

linoleic acid on the milk production, estrous cycle characteristics, and

reproductive performance of lactating dairy cattle'. Journal of Dairy Science, 95

(5):2442-2451.




Richardson L, Hanrahan JP, Donovan A, Martí JI, Fair S, Evans AC, Lonergan P

(2012) 'Effect of site of deposition on the fertility of sheep inseminated with

frozen-thawed semen'. Animal Reproduction Science, 131 (3-4):160-164.

Cummins SB, Lonergan P, Evans AC, Berry DP, Evans RD, Butler ST (2012)

'Genetic merit for fertility traits in Holstein cows: I. Production characteristics and

reproductive efficiency in a pasture-based system'. Journal of Dairy Science, 95

(3):1310-1322.

Chapwanya A, Meade KG, Foley C, Narciandi F, Evans AC, Doherty ML,

Callanan JJ, O'Farrelly C (2012) 'The postpartum endometrial inflammatory

response: a normal physiological event with potential implications for bovine

fertility'. Reproduction, fertility, and development .

Mullen MP, Forde N, Parr MH, Diskin MG, Morris DG, Nally JE, Evans AC,

Crowe MA (2012) 'Alterations in systemic concentrations of progesterone during

the early luteal phase affect RBP4 expression in the bovine uterus'. Reproduction,

fertility, and development, 24 (5):715-722.





Richardson L, Hanrahan JP, O'Hara L, Donovan A, Fair S, O'Sullivan M,

Carrington SD, Lonergan P, Evans AC; (2011) 'Ewe breed differences in fertility

after cervical AI with frozen-thawed semen and associated differences in sperm

penetration and physicochemical properties of cervical mucus'. Animal

Reproduction Science, 129 (1-2):37-43.

Swangchan-Uthai T, Walsh SW, Alexander SL, Cheng Z, Crowe MA, Evans AC,

Wathes DC; (2011) 'Comparison of mRNA for IGFs and their binding proteins in

the oviduct during the peri-oestrous period between dairy heifers and lactating

cows'. Reproduction (Cambridge, England), 142 (3):457-465.

Professor Oliver Fitzgerald

Haroon M, FitzGerald O (2012) 'Pathogenetic overview of psoriatic disease'. The

Journal of Rheumatology .

Haroon M, Kirby B, FitzGerald O (2012) 'High prevalence of psoriatic arthritis in

patients with severe psoriasis with suboptimal performance of screening

questionnaires'. Annals of Rheumatic Diseases .


Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A,

FitzGerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U (2012) 'Acute-phase

serum amyloid A regulates tumor necrosis factor α and matrix turnover and

predicts disease progression in patients with inflammatory arthritis before and

after biologic therapy'. Arthritis Rheumatology .

Helliwell PS, FitzGerald O, Mease PJ (2012) 'Development of composite

measures for psoriatic arthritis: a report from the GRAPPA 2010 annual meeting'.

Journal of Rheumatology .

FitzGerald O, Chandran V (2012) 'Update on biomarkers in psoriatic arthritis: a

report from the GRAPPA 2010 annual meeting'. The Journal of Rheumatology .

Gladman DD, Ritchlin CT, FitzGerald O (2012) 'The path forward to biomarker

discovery in psoriatic disease: a report from the GRAPPA 2010 annual meeting'.

The Journal of Rheumatology .

Bowes J, Ho P, Flynn E, Ali F, Marzo-Ortega H, Coates LC, Warren RB,

McManus R, Ryan AW, Kane D, Korendowych E, McHugh N, FitzGerald O,

Packham J, Morgan AW, Bruce IN, Barton A (2012) 'Comprehensive assessment

of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort'.

Annals of Rheumatic Diseases .

French HP, Fitzpatrick M, Fitzgerald O (2011) 'Responsiveness of physical

function outcomes following physiotherapy intervention for osteoarthritis of the

knee: an outcome comparison study'. Physiotherapy .

Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A,

Fitzgerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U (2011) 'A-SAA

regulates TNFα and matrix turnover and predicts disease progression in patients

pre/post biologic therapy'. Arthritis Rheumatology .

Helliwell PS, FitzGerald O, Fransen J, Gladman DD, Kreuger GG, Callis-Duffin

K, McHugh N, Mease PJ, Strand V, Waxman R, Azevedo VF, Beltran Ostos A,

Carneiro S, Cauli A, Espinoza LR, Flynn JA, Hassan N, Healy P, Kerzberg EM,

Lee YJ, Lubrano E, Marchesoni A, Marzo-Ortega H, Porru G, Moreta EG, Nash

P, Raffayova H, Ranza R, Raychaudhuri SP, Roussou E, Scarpa R, Song YW,

Soriano ER, Tak PP, Ujfalussy I, de Vlam K, Walsh JA (2011) 'Helliwell PS,

FitzGerald O, Fransen J, Gladman DD, Kreuger GG, Callis-Duffin K, McHugh N,

Mease PJ, Strand V, Waxman R, Azevedo VF, Beltran Ostos A, Carneiro S, Cauli

A, Espinoza LR, Flynn JA, Hassan N, Healy P, Kerzberg EM, Lee YJ, Lubrano E,

Marchesoni A, Marzo-Ortega H, Porru G, Moreta EG, Nash P, Raffayova H,

Ranza R, Raychaudhuri SP, Roussou E, Scarpa R, Song YW, Soriano ER, Tak PP,

Ujfalussy I, de Vlam K, Walsh JA'. Annals of Rheumatic Diseases .

Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ,

Bresnihan B, Fearon U (2011) 'Differential expression of NK receptors CD94 and

NKG2A by T cells in rheumatoid arthritis patients in remission compared to

active disease'. PLoS ONE .

Fitzgerald O, Helliwell P, Mease P, Mumtaz A, Coates L, Pedersen R, Nab H,

Molta C; (2011) 'Application of composite disease activity scores in psoriatic

arthritis to the PRESTA data set'. Annals of Rheumatic Diseases .

FitzGerald O, Helliwell P, Mease P, Mumtaz A, Coates L, Pedersen R, Nab H,

Molta C (2011) 'Application of composite disease activity scores in psoriatic

arthritis to the PRESTA data set'. Annals of Rheumatic Diseases .

Haroon M, Fitzgerald O (2011) 'Vitamin D and its emerging role in

immunopathology'. Clinical Rheumatology .

Winchester R, Minevich G, Steshenko V, Kirby B, Kane D, Greenberg DA,

Fitzgerald O; (2011) 'HLA associations reveal genetic heterogeneity in psoriatic

arthritis and in the psoriasis phenotype'. Arthritis Rheumatology .

Adams R, Craig BM, Walsh CD, Veale DJ, Bresnihan B, FitzGerald O, Barry M;

(2011) 'The impact of a revised EQ-5D population scoring on preference-based

utility scores in an inflammatory arthritis cohort'. Value in health : the journal of

the International Society for Pharmacoeconomics and Outcomes Research, 14

(6):921-927.

Schmitz S, Adams R, Walsh CD, Barry M, Fitzgerald O; (2011) 'A mixed

treatment comparison of the efficacy of anti-TNF agents in rheumatoid arthritis

for methotrexate non-responders demonstrates differences between treatments: a

Bayesian approach'. Annals of Rheumatic Diseases .

Gossec L, Smolen JS, Gaujoux-Viala C, Ash Z, Marzo-Ortega H, van der Heijde

D, Fitzgerald O, Aletaha D, Balint P, Boumpas D, Braun J, Breedveld FC,

Burmester G, Cañete JD, de Wit M, Dagfinrud H, de Vlam K, Dougados M,

Helliwell P, Kavanaugh A, Kvien TK, Landewé, Luger T, Maccarone M,

McGonagle D, McHugh N, McInnes IB, Ritchlin C, Sieper J, Tak PP, Valesini G,

Vencovsky J, Winthrop KL, Zink A, Emery P; (2011) 'European League Against

Rheumatism recommendations for the management of psoriatic arthritis with

pharmacological therapies'. Annals of Rheumatic Diseases .

Professor William Gallagher

Collins BC, Miller CA, Sposny A, Hewitt P, Wells M, Gallagher WM, Pennington

SR (2012) 'Development of a pharmaceutical hepatotoxicity biomarker panel

using a discovery to targeted proteomics approach'. Molecular & Cellular

Proteomics, 11 (8):394-410.

Joyce CW, Murphy IG, Rafferty M, Ryan D, McDermott EW, Gallagher WM

(2012) 'Tumor profiling using protein biomarker panels in malignant melanoma:

application of tissue microarrays and beyond'. Expert Review of Proteomics, 9

(9):415-423.

Brennan DJ, O'Connor DP, Laursen H, McGee SF, McCarthy S, Zagozdzon R,

Rexhepaj E, Culhane AC, Martin FM, Duffy MJ, Landberg G, Ryden L, Hewitt

SM, Kuhar MJ, Bernards R, Millikan RC, Crown JP, Jirstrom K, Gallagher WM

(2012) 'The cocaine- and amphetamine-regulated transcript mediates ligand-

independent activation of ERα, and is an independent prognostic factor in node-

negative breast cancer'. Oncogene, 31 (30):3483-3494.

Collins BC, Gallagher WM (2012) 'Focus on cancer proteomics'. Proteomics, 12

(13):2065-2066.

Geiger T, Madden SF, Gallagher WM, Cox J, Mann M (2012) 'Proteomic portrait

of human breast cancer progression identifies novel prognostic markers'. Cancer

Research, 72 (9):428-439.

Zagozdzon AM, O'Leary P, Callanan JJ, Crown J, Gallagher WM, Zagozdzon R

(2012) 'Generation of a new bioluminescent model for visualisation of mammary

tumour development in transgenic mice'. BMC Cancer, 12 (209).

Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG,

Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L; Australian


Ovarian Cancer Study Group, Salako MA, Smyth JF, Hagemann T, Brennan DJ,

Bowtell DD, Balkwill FR (2012) 'A dynamic inflammatory cytokine network in

the human ovarian cancer microenvironment'. Cancer research, 72 (1):66-75.





Vader P, van der Meel R, Symons MH, Fens MH, Pieters E, Wilschut KJ, Storm

G, Jarzabek M, Gallagher WM, Schiffelers RM, Byrne AT (2011) 'Examining the

role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-

mediated approach'. Angiogenesis, 14 (4):457-466.

Power KA, Grad S, Rutges JP, Creemers LB, van Rijen MH, O'Gaora P, Wall JG,

Alini M, Pandit A, Gallagher WM (2011) 'Identification of cell surface-specific

markers to target human nucleus pulposus cells: expression of carbonic anhydrase

XII varies with age and degeneration'. Arthritis Rheumatology, 63 (12):3876-

3886.

Maher SG, McDowell DT, Collins BC, Muldoon C, Gallagher WM, Reynolds JV

(2011) 'Serum proteomic profiling reveals that pretreatment complement protein

levels are predictive of esophageal cancer patient response to neoadjuvant

chemoradiation'. Annals of Surgery, 254 (5):809-816.

O'Donovan N, Byrne AT, O'Connor A E, McGee S, Gallagher W M, and Crown J

(2011) 'Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine

kinase inhibitors in HER-2 positive breast cancer cells'. Investigational New

Drugs, 29 (5):752-759.

O'Neill AJ, Prencipe M, Dowling C, Fan Y, Mulrane L, Gallagher WM, O'Connor

D, O'Connor R, Devery A, Corcoran C, Rani S, O'Driscoll L, Fitzpatrick JM,

Watson RW (2011) 'Characterisation and manipulation of docetaxel resistant

prostate cancer cell lines'. MOL CANCER, 10 (126).

Sernbo S, Gustavsson E, Brennan DJ, Gallagher WM, Rexhepaj E, Rydnert F,

Jirstrom K, Borrebaeck CA, Ek S (2011) 'The tumour suppressor SOX11 is

associated with improved survival among high grade epithelial ovarian cancers

and is regulated by reversible promoter methylation'. BMC Cancer, 11 (405).

Hams E, Saunders SP, Cummins EP, O'Connor A, Tambuwala MT, Gallagher

WM, Byrne A, Campos-Torres A, Moynagh PM, Jobin C, Taylor CT, Fallon PG;

(2011) 'The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic

shock via alternative activation of macrophages and IL-10 production by B1 cells'.

Shock, 36 (3):295-302.

Zagozdzon R, Gallagher WM, Crown, J (2011) 'Truncated HER2: implications for

HER2-targeted therapeutics'. Drug Discovery Today, 16 (17-18):812-816.

Coward J, Kulbe H, Chakravarty P, Leader D A, Vassileva V, Leinster D A,

Thompson R, Schioppa T, Nemeth J A, Vermeulin J, Singh N, Avril N E,

Cummings J, Rexhepaj E, Jirstrom K, Gallagher W M, Brennan D J, McNeish I

A, Balkwill F R (2011) 'Interleukin-6 as a therapeutic target in human ovarian

cancer'. Clinical Cancer Research, 17 (18):6083-6096.

Professor Declan Gerard Gilheany

Peter A. Byrne and Declan G. Gilheany (2012) 'Unequivocal Experimental

Evidence for a Unified Lithium Salt-Free Wittig Reaction Mechanism for All


Phosphonium Ylide Types: Reactions with β-Heteroatom-Substituted Aldehydes

Are Consistently Selective for cis-Oxaphosphetane-Derived Products'. Journal of

the American Chemical Society, 134 (22):9225-9239.

Kamalraj V. Rajendran, Jaya S. Kudavalli, Katherine S. Dunne, Declan G.

Gilheany (2012) 'A U-Turn in the Asymmetric Appel Reaction: Stereospecific

Reduction of Diastereomerically Enriched Alkoxyphosphonium Salts Allows the

Asymmetric Synthesis of P-Stereogenic Phosphanes and Phosphane Boranes'.

European Journal of Organic Chemistry, 2012 (14):2720-2723.

Peter A. Byrne , Kamalraj V. Rajendran , Jimmy Muldoon and Declan G.

Gilheany (2012) 'A convenient and mild chromatography-free method for the

purification of the products of Wittig and Appel reactions'. Organic and

Biomolecular Chemistry, 10 (17):3531-3537.

Kamalraj V. Rajendran, Damien J. Carr, Declan G. Gilheany (2011) 'An easy and

short preparation of pentachloroacetone by selective dechlorination of

hexachloroacetone under Appel conditions'. Tetrahedron Letters, 52 (52):7113-

7115.

Kamalraj V. Rajendran and Declan G. Gilheany (2011) 'Simple unprecedented

conversion of phosphine oxides and sulfides to phosphine boranes using sodium

borohydride'. Chemical Communications, 48 :817-819.

Professor Catherine Godson

Bson E, McGillicuddy FC, Harford KA, Corrigan N, Higgins DF, Maderna P,

Roche HM, Godson C. (2012) 'Lipoxin A4 attenuates adipose inflammation'.

FASEB Journal, 26 (10):4287-4294.

Borgeson E, Mc Gillicuddy FC, Harford KA, Corrigan N, Higgins DF, Maderna

P, Roch HM, Godson C (2012) 'Lipoxin A4 attenuates adipose inflammation'.

FASEB Journal .

Williams WW, Salem RM, McKnight AJ, Sandholm N, Forsblom C, Taylor A,

Guiducci C, McAteer JB, McKay GJ, Isakova T, Brennan EP, Sadlier DM, Palmer

C, Söderlund J, Fagerholm E, Harjutsalo V, Lithovius R, Gordin D, Hietala K,

Kytö J, Parkkonen M, Rosengård-Bärlund M, Thorn L, Syreeni A, Tolonen N,

Saraheimo M, Wadén J, Pitkäniemi J, Sarti C, Tuomilehto J, Tryggvason K,

Osterholm AM, He B, Bain S, Martin F, Godson C, Hirschhorn JN, Maxwell AP,

Groop PH, Florez JC (2012) 'Association Testing of Previously Reported Variants

in a Large Case-Control Meta-Analysis of Diabetic Nephropathy'. Diabetes .

Brennan EP, Morine MJ, Walsh DW, Roxburgh SA, Lindenmeyer MT, Brazil DP,

Gaora PO, Roche HM, Sadlier DM, Cohen CD, Godson C, Martin F (2012) 'Next-

generation sequencing identifies TGF-β1-associated gene expression profiles in

renal epithelial cells reiterated in human diabetic nephropathy'. Biochimica et

biophysica acta, 1822 (4):589-599.

Brennan, EP; Morine, MJ; Walsh, DW; Roxburgh, SA; Lindenmeyer, MT; Brazil,

DP; Gaora, PO; Roche, HM; Sadlier, DM; Cohen, CD; The GENIE, Consortium;

Godson, C; Martin, F; (2012) 'Next-generation sequencing identifies TGF-β1-

associated gene expression profiles in renal epithelial cells reiterated in human

diabetic nephropathy'. Biochimica Et Biophysica Acta-Molecular Basis of

Disease, 1822 (4):5https://rms.u89-599.

O'Donovan HC, Hickey F, Brazil DP, Kavanagh DH, Oliver N, Martin F, Godson

C, Crean J (2012) 'Connective tissue growth factor antagonizes transforming



growth factor-β1/Smad signalling in renal mesangial cells'. Biochem J, 441 :499-

510.

Professor Stephen Gordon

Chen J, Uplekar S, Gordon SV, Cole ST. (2012) 'A point mutation in cycA

partially contributes to the D-cycloserine resistance trait of Mycobacterium bovis

BCG vaccine strains'. PLoS ONE .

Rodriguez-Campos S, Schrch AC, Dale J, Lohan AJ, Cunha MV, Botelho A, De

Cruz K, Boschiroli ML, Boniotti MB, Pacciarini M, Garcia-Pelayo MC, Romero

B, de Juan L, Domínguez L, Gordon SV, van Soolingen D, Loftus B, Berg S,

Hewinson RG, Aranaz A, Smith NH (2012) 'European 2--a clonal complex of

Mycobacterium bovis dominant in the Iberian Peninsula'. Gene, 12 (4):866-872.

Ussery DW, Gordon SV (2012) 'Two novel methods for using genome sequences

to infer taxonomy'. Microbiology (Reading, England), 158 (Pt 6).

Chen JM, Uplekar S, Gordon SV, Cole ST (2012) 'A Point Mutation in cycA

Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium

bovis BCG Vaccine Strains'. PLoS ONE, 7 (8).

Magee DA, Taraktsoglou M, Killick KE, Nalpas NC, Browne JA, Park SD,

Conlon KM, Lynn DJ, Hokamp K, Gordon SV, Gormley E, MacHugh DE (2012)

'Global gene expression and systems biology analysis of bovine monocyte-derived

macrophages in response to in vitro challenge with Mycobacterium bovis'. PLoS

ONE, 7 (2).

Killick KE, Browne JA, Park SD, Magee DA, Martin I, Meade KG, Gordon SV,

Gormley E, O'Farrelly C, Hokamp K, MacHugh DE (2011) 'Genome-wide

transcriptional profiling of peripheral blood leukocytes from cattle infected with

Mycobacterium bovis reveals suppression of host immune genes'. BMC

Genomics, 12 .

Professor Andrew Green

Jenkinson EM, Clayton-Smith J, Mehta S, Bennett C, Reardon W, Green A,

Pearce SH, De Michele G, Conway GS, Cilliers D, Moreton N, Davis JR, Trump

D, Newman WG. (2012) 'Perrault syndrome: further evidence for genetic

heterogeneity'. Journal of Neurology .

Anney R, Klei L, Pinto D, Almeida J, Bacchelli E, Baird G, Bolshakova N, B S,

Bolton PF, Bourgeron T, Brennan S, Brian J, Casey J, Conroy J, Correia C,

Corsello C, Crawford EL, de Jonge M, Delorme R, Duketis E, Duque F, Estes A,

Farrar P, Fernandez BA, Folstein SE, Fombonne E, Gilbert J, Gillberg C, Glessner

JT, Green A, Green J, Guter SJ, Heron EA, Holt R, Howe JL, Hughes G, Hus V,

Igliozzi R, Jacob S, Kenny GP, Kim C, Kolevzon A, Kustanovich V, Lajonchere

CM, Lamb JA, Law-Smith M, Leboyer M, Le Couteur A, Leventhal BL, Liu XQ,

Lombard F, Lord C, Lotspeich L, Lund SC, Magalhaes TR, Mantoulan C,

McDougle CJ, Melhem NM, Merikangas A, Minshew NJ, Mirza GK, Munson J,

Noakes C, Papanikolaou K, Pagnamenta AT, Parrini B, Paton T, Pickles A, Posey

DJ, Poustka F, Ragoussis J, Regan R, Renshaw K, Roberts W, Roeder K, Roge B,

Rutter ML, Schlitt S, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V,

Sykes N, Tancredi R, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van

Engeland H, Vincent JB, Volkmar F, Vorstman J, Wallace S, Wing K,

Wittemeyer K, Wood S, Zurawiecki D, Zwaigenbaum L, Bailey AJ, Battaglia A,



Cantor RM, Coon H, Cuccaro ML, Dawson G, Ennis S, Freitag CM, Geschwind

DH, Haines JL, Klauck SM, McMahon WM, Maestrini E, Miller J, Monaco AP,

Nelson SF, Nurnberger JI Jr, Oliveira G, Parr JR, Pericak-Vance MA, Piven J,

Schellenberg GD, Scherer SW, Vicente AM, Wassink TH, Wijsman EM,

Betancur C, Buxbaum JD, Cook EH, Gallagher L, Gill M, Hallmayer J, Paterson

AD, Sutcliffe JS, Szatmari P, Vieland VJ, Hakonarson H, Devlin B (2012)

'Individual common variants exert weak effects on risk for Autism Spectrum

Disorders'. Human Molecular Genetics .

Dunlop MG, Dobbins SE, Farrington SM, Jones AM, Palles C, Whiffin N, Tenesa

A, Spain S, Broderick P, Ooi LY, Domingo E, Smillie C, Henrion M, Frampton

M, Martin L, Grimes G, Gorman M, Semple C, Ma YP, Barclay E, Prendergast J,

Cazier JB, Olver B, Penegar S, Lubbe S, Chander I, Carvajal-Carmona LG,

Ballereau S, Lloyd A, Vijayakrishnan J, Zgaga L, Rudan I, Theodoratou E; The

Colorectal Tumour Gene Identification (CORGI) Consortium, Thomas H, Maher

E, Evans G, Walker L, Halliday D, Lucassen A, Paterson J, Hodgson S, Homfray

T, Side L, Izatt L, Donaldson A, Tomkins S, Morrison P, Brewer C, Henderson A,

Davidson R, Murday V, Cook J, Haites N, Bishop T, Sheridan E, Green A, Marks

C, Carpenter S, Broughton M, Greenhalge L, Suri M, Starr JM, Deary I, Kirac I,

Kovacević D, Aaltonen LA, Renkonen-Sinisalo L, Mecklin JP, Matsuda K,

Nakamura Y, Okada Y, Gallinger S, Duggan DJ, Conti D, Newcomb P, Hopper J,

Jenkins MA, Schumacher F, Casey G, Easton D, Shah M, Pharoah P, Lindblom A,

Liu T; The Swedish Low-Risk Colorectal Cancer Study Group (2012) 'Common

variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer

risk'. Nature Genetics .

Casey J, Kawaguchi R, Morrissey M, Sun H, McGettigan P, Nielsen JE, Conroy J,

Regan R, Kenny E, Cormican P, Morris DW, Tormey P, Ni Chroinin M, Kennedy

BN, Lynch S, Green A, Ennis S.; (2011) 'First implication of STRA6 mutations in

isolated anophthalmia, microphthalmia, and coloboma: A new dimension to the

STRA6 phenotype'. Human Mutation, 32 (12):1417-1426.

Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC,

Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T,

Bolshakova N, Bolton PF, Bourgeron T, Brennan S, Cali P, Correia C, Corsello C,

Coutanche M, Dawson G, de Jonge M, Delorme R, Duketis E, Duque F, Estes A,

Farrar P, Fernandez BA, Folstein SE, Foley S, Fombonne E, Freitag CM, Gilbert

J, Gillberg C, Glessner JT, Green J, Guter SJ, Hakonarson H, Holt R, Hughes G,

Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Lamb JA, Leboyer M, Le

Couteur A, Leventhal BL, Lord C, Lund SC, Maestrini E, Mantoulan C, Marshall

CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A,

Miller J, Minopoli F, Mirza GK, Munson J, Nelson SF, Nygren G, Oliveira G,

Pagnamenta AT, Papanikolaou K, Parr JR, Parrini B, Pickles A, Pinto D, Piven J,

Posey DJ, Poustka A, Poustka F, Ragoussis J, Roge B, Rutter ML, Sequeira AF,

Soorya L, Sousa I, Sykes N, Stoppioni V, Tancredi R, Tauber M, Thompson AP,

Thomson S, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Vorstman JA,

Wallace S, Wang K, Wassink TH, White K, Wing K, Wittemeyer K, Yaspan BL,

Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H,

Cuccaro ML, Geschwind DH, Haines JL, Hallmayer J, Monaco AP, Nurnberger JI

Jr, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P,

Vieland VJ, Wijsman EM, Green A, Gill M, Gallagher L, Vicente A, Ennis S.;

(2011) 'A novel approach of homozygous haplotype sharing identifies candidate

genes in autism spectrum disorder'. Human Genetics .

Nowakowska BA, de Leeuw N, Ruivenkamp CA, Sikkema-Raddatz B, Crolla JA,

Thoelen R, Koopmans M, den Hollander N, van Haeringen A, van der Kevie-

Kersemaekers AM, Pfundt R, Mieloo H, van Essen T, de Vries BB, Green A,

Reardon W, Fryns JP, Vermeesch JR.; (2011) '] Parental insertional balanced

translocations are an important cause of apparently de novo CNVs in patients with

developmental anomalies'. European Journal of Human Genetics .

Professor Patrick Guiry

Barth, Caroline; Guiry, Patrick J. (2012) 'The medicinal chemistry of stable

synthetic leukotriene B-3 and B-4 analogues'. Future Medicinal Chemistry, 4

(8):1007-1014.

Milhau, Ludovic; Guiry, Patrick J. (2012) 'Palladium-Catalyzed Enantioselective

Allylic Substitution'. Topics in Organometallic Chemistry: Medicinal

Organometallic Chemistry, 38 :95-153.

Doran, Robert; Duggan, Lesley; Singh, Surrendra; Duffy, Colm; Guiry, Patrick J.

(2011) 'Asymmetric Synthesis of (+)-Tanikolide and the ss-Methyl-Substituted

Analogues of (+)-Tanikolide and (-)-Malyngolide'. European Journal of Organic

Chemistry, (35):7097-7116.

McKeon, Sean C.; Mueller-Bunz, Helge; Guiry, Patrick J. (2011) 'Synthesis of

Thiazoline-Oxazoline Ligands and Their Application in Asymmetric Catalysis'.

European Journal of Organic Chemistry, (35):7107-7115.

Dr Chandralal Hewage

Elsawy MA, Hewage C, Walker B (2012) 'Racemisation of N-Fmoc

phenylglycine under mild microwave-SPPS and conventional stepwise SPPS

conditions: attempts to develop strategies for overcoming this'. Journal of peptide

science : an official publication of the European Peptide Society, 18 (5):302-311.

Professor Desmond Gerard Higgins

Shi W, Zhu C, Zheng W, Carr MJ, Higgins DG, Zhang Z (2012) 'Subgenotype

reclassification of genotype B hepatitis B virus'. BMC gastroenterology, 12 (1).

Shi W, Carr MJ, Dunford L, Zhu C, Hall WW, Higgins DG (2012) 'Identification

of novel inter-genotypic recombinants of human hepatitis B viruses by large-scale

phylogenetic analysis'. Virology, 427 (1):51-59.

Shi W, Freitas IT, Zhu C, Zheng W, Hall WW, Higgins DG (2012)

'Recombination in hepatitis C virus: identification of four novel naturally

occurring inter-subtype recombinants'. PLoS ONE, 7 (7).

Guida A, Lindstädt C, Maguire SL, Ding C, Higgins DG, Corton NJ, Berriman M,

Butler G (2011) 'Using RNA-seq to determine the transcriptional landscape and

the hypoxic response of the pathogenic yeast Candida parapsilosis'. Genomics, 12

.

Guida A, Lindstaedt C, Maguire SL, Ding C, Higgins DG, Corton NJ, Berriman

M, Butler G; (2011) 'Using RNA-seq to determine the transcriptional landscape

and the hypoxic response of the pathogenic yeast Candida parapsilosis'. BMC

Genomics, 12 .

Sievers F, Wilm A, Dineen D, Gibson TJ, Karplus K, Li W, Lopez R, McWilliam

H, Remmert M, Söding J, Thompson JD, Higgins DG.; (2011) 'Fast, scalable




generation of high-quality protein multiple sequence alignments using Clustal

Omega'. Molecular systems biology, 7 .

Professor Michael Keane

O'Neill AC, McCarthy C, Ridge CA, Mitchell P, Hanrahan E, Butler M, Keane

MP, Dodd JD.; (2011) 'Rapid Needle-Out Patient-Rollover Time after

Percutaneous CT-guided Transthoracic Biopsy of Lung Nodules: Effect on

Pneumothorax Rate'. Radiology .

Dr Breandán Kennedy

Fichtnera I, Cinatl jr. J, Michaelis M, Sanders LC, Hilger R, Kennedy BN,

Reynolds AL, Hackenberg F, Lally G, Quinn SJ, McRae I and Tacke M (2012) 'In

Vitro and In Vivo Investigations into the Carbene Silver Acetate'. Letters in Drug

Design & Discovery .

Reynolds AL, Blacque OE, Kennedy BN. (2012) 'The genetics of outer segment

morphogenesis in zebrafish'. Advances in Experimental Medical Biology, 723

:431-441.






Sapetto-Rebow B, McLoughlin SC, O'Shea LC, O'Leary O, Willer JR, Alvarez Y,

Collery R, O'Sullivan J, Van Eeden F, Hensey C, Kennedy BN. (2011) 'Maternal

topoisomerase II alpha, not topoisomerase II beta, enables embryonic

development of zebrafish top2a-/- mutants'. BMC Developmental Biology, 11 .

Professor Boris Kholodenko

Frank TD, Cheong A, Okada-Hatakeyama M, Kholodenko BN (2012) 'Catching

transcriptional regulation by thermostatistical modeling'. Physical Biology, 9 (4).

Birtwistle MR, Rauch J, Kiyatkin A, Aksamitiene E, Dobrzynski M, Hoek JB,

Kolch W, Ogunnaike BA, Kholodenko BN (2012) 'Emergence of bimodal cell

population responses from the interplay between analog single-cell signaling and

protein expression noise'. BMC systems biology, 6 .

Frank, TD; Cheong, A; Okada-Hatakeyama, M; Kholodenko, BN (2012)

'Catching transcriptional regulation by thermostatistical modeling'. Physical

Biology .

Kholodenko B, Yaffe MB, Kolch W (2012) 'Computational approaches for

analyzing information flow in biological networks'. Science signaling, 5 (220).

Tsyganov MA, Kolch W, Kholodenko BN (2012) 'The topology design principles

that determine the spatiotemporal dynamics of G-protein cascades'. Molecular

BioSystems, 8 (3):730-743.

Aksamitiene E, Kiyatkin A, Kholodenko BN (2012) 'Cross-talk between

mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance'.

Biochemical Society Transactions, 40 (1):139-146.

Nguyen LK, Matallanas D, Croucher DR, von Kriegsheim A, Kholodenko BN

(2012) 'Signalling by protein phosphatases and drug development: a systems-

centred view'. The FEBS journal .




http://www.springerlink.com/content/r42924w780515p11/?MUD=MP

Santra T, Kholodenko B, Kolch W (2012) 'An integrated Bayesian framework for

identifying phosphorylation networks in stimulated cells'. Frontiers in Modeling

and Control of Breathing, 736 :59-80.

Frank TD, Carmody AM, Kholodenko BN (2012) 'Versatility of cooperative

transcriptional activation: a thermodynamical modeling analysis for greater-than-

additive and less-than-additive effects'. PLoS ONE, 7 (4).

Fey D, Croucher DR, Kolch W, Kholodenko BN (2012) 'Crosstalk and signaling

switches in mitogen-activated protein kinase cascades'. Frontiers in physiology, 3

.

Frank, T.D., Carmody, A.M., Kholodenko, B.N. (2012) 'Versatility of cooperative

transcriptional activation'. PLoS ONE .

Nguyen LK, Munoz-García J, Maccario H, Ciechanover A, Kolch W, Kholodenko

BN (2011) 'Switches, excitable responses and oscillations in the Ring1B/Bmi1

ubiquitination system'. PLoS computational biology, 7 (12).

Professor Therese Kinsella

Reid HM, Turner EC, Mulvaney EP, Hyland PB, McLean C, Kinsella BT. (2012)

'Interaction of the human prostacyclin receptor and the NHERF4 family member

intestinal and kidney enriched PDZ protein (IKEPP)'. Biochima Et Biophysica

Acta - Molecular Cell Research, 1823 (10):1998-2012.

Keating GL, Turner EC, Kinsella BT. (2012) 'Regulation of the human

prostacyclin receptor gene in megakaryocytes: Major roles for C/EBPδ and PU.1'.

Biochimica et biophysica acta, 1819 :428-445.

Professor Ulla Knaus

Corcionivoschi N, Alvarez LA, Sharp TH, Strengert M, Alemka A, Mantell J,

Verkade P, Knaus UG, Bourke B (2012) 'Mucosal reactive oxygen species

decrease virulence by disrupting Campylobacter jejuni phosphotyrosine signaling'.

Cell, 12 (1):47-59.

Ghosh CC, Mukherjee A, David S, Knaus UG, Stearns-Kurosawa DJ, Kurosawa

S, Parikh SM. (2012) 'Impaired function of the Tie-2 receptor contributes to

vascular leakage and lethality in anthrax'. Proceedings of the National Academy of

Sciences USA, 109 (25):10024-10029.

Munson, JM, Fried, L, Rowson, SA, Bonner, MY, Karumbaiah, L, Diaz, B,

Courtneidge, SA, Knaus, UG, Brat, DJ, Arbiser, JL, Bellamkonda, RV (2012)

'Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic

efficacy against glioma'. science translational medicine, 4 (127).

Von Loehneysen, K, Noack, D, Hayes, P, Friedman, JS, Knaus, UG (2012)

'Constitutive NADPH oxidase 4 activity resides in the composition of the B-loop

and the penultimate C terminus'. Journal of Biological Chemistry, 287 (12):8737-

8745.

Al Ghouleh, I, Khoo, NK, Knaus, UG, Griendling, KK, Touyz, RM, Thannickal,

VJ, Barchowsky, A, Nauseef, WM, Kelley, EE, Bauer, PM, Darley-Usmar, V,

Shiva, S., Cifuentes-Pagano, E, Freeman, BA, Gladwin, MT, Pagano, PJ (2011)

'Oxidases and peroxidases in cardiovascular and lung disease:new concepts in

reactive oxygen species signaling'. Free Radical Biology and Medicine .

Professor Walter Kolch




Zebisch A, Wölfler A, Fried I, Wolf O, Lind K, Bodner C, Haller M, Drasche A,

Pirkebner D, Matallanas D, Rath O, Blyth K, Delwel R, Taskesen E,

Quehenberger F, Kolch W, Troppmair J, Sill H (2012) 'Frequent loss of RAF

kinase inhibitor protein expression in acute myeloid leukemia'. Leukemia, 26

(8):1842-1849.

Preisinger C, Schwarz JP, Bleijerveld OB, Corradini E, Müller PJ, Anderson KI,

Kolch W, Scholten A, Heck AJ (2012) 'Imatinib-dependent tyrosine

phosphorylation profiling of Bcr-Abl-positive chronic myeloid leukemia cells'.

Leukemia .

Birtwistle MR, Rauch J, Kiyatkin A, Aksamitiene E, Dobrzynski M, Hoek JB,

Kolch W, Ogunnaike BA, Kholodenko BN (2012) 'Emergence of bimodal cell

population responses from the interplay between analog single-cell signaling and

protein expression noise'. BMC systems biology, 6 .

Kholodenko B, Yaffe MB, Kolch W (2012) 'Computational approaches for

analyzing information flow in biological networks'. Science signaling, 5 (220).

von Thun A, Birtwistle M, Kalna G, Grindlay J, Strachan D, Kolch W, von

Kriegsheim A, Norman JC (2012) 'ERK2 drives tumour cell migration in three-

dimensional microenvironments by suppressing expression of Rab17 and liprin-

β2'. Cell, 125 (Pt 6):1465-1477.

Tsyganov MA, Kolch W, Kholodenko BN (2012) 'The topology design principles

that determine the spatiotemporal dynamics of G-protein cascades'. Molecular

BioSystems, 8 (3):730-743.

Santra T, Kholodenko B, Kolch W (2012) 'An integrated Bayesian framework for

identifying phosphorylation networks in stimulated cells'. Frontiers in Modeling

and Control of Breathing, 736 :59-80.

Fey D, Croucher DR, Kolch W, Kholodenko BN (2012) 'Crosstalk and signaling

switches in mitogen-activated protein kinase cascades'. Frontiers in physiology, 3

.

Nguyen LK, Munoz-García J, Maccario H, Ciechanover A, Kolch W, Kholodenko

BN (2011) 'Switches, excitable responses and oscillations in the Ring1B/Bmi1

ubiquitination system'. PLoS computational biology, 7 (12).

Professor Gil Lee

Muzard, J., Fields, C., O'Mahony, J.J. and Lee, GU (2012) 'Probing the Soybean

Bowman-Birk Inhibitor Using Recombinant Antibody Fragments'. Journal of

Agricultural and Food Chemistry, 60 (24):6164-6172.

Martines, E, Zhong, J, Muzard, J, Lee, AC, Akhremitchev, BB, Suter, DM, Lee,

GU (2012) 'Single-Molecule Force Spectroscopy of the Aplysia Cell Adhesion

Molecule Reveals Two Homophilic Bonds'. Biophysical Journal, 103 (4):649-

657.

Muzard, J., Platt, M., Lee, G.U. (2012) 'M13 Bacteriophage-Activated

Superparamagnetic Beads for Affinity Separation'. Small, 8 (15):2403-2411.

Platt, M., Willmott, G., and Lee, G.U (2012) 'Resistive Pulse Sensing of Analyte-

Induced Multicomponent Rod Aggregation Using Tunable Pores'. Small, 8

(15):2436-2444.

Willmott, GR, Platt, M, and Lee, GU (2012) 'Resistive pulse sensing of magnetic

beads and supraparticle structures using tunable pores'. Journal of Applied


Physics, 6 (1).

Fields, C., Mallee, P., Muzard, J., Lee, G.U. (2012) 'Isolation of Bowman-Birck-

Inhibitor from Soybean Extracts using Novel Peptide Probes and High Gradient

Magnetic Separation'. Food Chemistry, 134 (4):1831-1838.

Zhang Y, DaSilva M, Ashall B, Doyle G, Zerulla D, Sands TD, Lee GU.; (2011)

'Magnetic manipulation and optical imaging of an active plasmonic single-particle

Fe-Au nanorod'. Langmuir, 27 (24):15292-15298.

Professor Brendan Loftus

Wuest SE, O'Maoileidigh DS, Rae L, Kwasniewska K, Raganelli A, Hanczaryk K,

Lohan AJ, Loftus B, Graciet E, Wellmer F (2012) 'Molecular basis for the

specification of floral organs by APETALA3 and PISTILLATA'. Proceedings of

the National Academy of Sciences of the United States of America, 109

(33):13452-13457.

Kröger C, Dillon SC, Cameron AD, Papenfort K, Sivasankaran SK, Hokamp K,

Chao Y, Sittka A, Hébrard M, Händler K, Colgan A, Leekitcharoenphon P,

Langridge GC, Lohan AJ, Loftus B, Lucchini S, Ussery DW, Dorman CJ,

Thomson NR, Vogel J, Hinton JC (2012) 'The transcriptional landscape and small

RNAs of Salmonella enterica serovar Typhimurium'. Proceedings of the National

Academy of Sciences of the United States of America, 109 (20):1-86.

Pozzi C, Waters EM, Rudkin JK, Schaeffer CR, Lohan AJ, Tong P, Loftus BJ,

Pier GB, Fey PD, Massey RC and O'Gara JP (2012) 'Methicillin Resistance Alters

the Biofilm Phenotype and Attenuates Virulence in Staphylococcus aureus

Device-Associated Infections'. PLoS Pathogens, 8 (4):e-1002626.

Professor Patrick Lonergan





810.

Gath VP, Crowe MA, O'Callaghan D, Boland MP, Duffy P, Lonergan P, Mulligan

FJ (2012) 'Effects of diet type on establishment of pregnancy and embryo

development in beef heifers'. Animal Reproduction Science, 133 (3-4):139-145.

Fair T, Lonergan P (2012) 'The role of progesterone in oocyte acquisition of

developmental competence'. Reproduction in Domestic Animals, 47 Suppl 4 :142-

147.

Eozenou C, Carvalho AV, Forde N, Giraud-Delville C, Gall L, Lonergan P,

Auguste A, Charpigny G, Richard C, Pannetier M, Sandra O (2012) 'FOXL2 is

regulated during the bovine estrous cycle and its expression in the endometrium is

independent of conceptus-derived interferon tau'. Biology of reproduction, 87 (2).

Maillo V, Rizos D, Besenfelder U, Havlicek V, Kelly AK, Garrett M, Lonergan P

(2012) 'Influence of lactation on metabolic characteristics and embryo

development in postpartum Holstein dairy cows'. Journal of Dairy Science, 95

(7):3865-3876.

Mamo S, Mehta JP, Forde N, McGettigan P, Lonergan P (2012) 'Conceptus-

endometrium crosstalk during maternal recognition of pregnancy in cattle'.

Biology of reproduction, 87 (1):1-9.



Hutchinson IA, Hennessy AA, Waters SM, Dewhurst RJ, Evans AC, Lonergan P,

Butler ST (2012) 'Effect of supplementation with different fat sources on the

mechanisms involved in reproductive performance in lactating dairy cattle'.

Theriogenology, 78 (1):12-27.

Cummins SB, Lonergan P, Evans AC, Butler ST (2012) 'Genetic merit for fertility

traits in Holstein cows: II. Ovarian follicular and corpus luteum dynamics,

reproductive hormones, and estrus behavior'. Journal of Dairy Science, 95

(7):3698-3710.

Cummins SB, Waters SM, Evans AC, Lonergan P, Butler ST (2012) 'Genetic

merit for fertility traits in Holstein cows: III. Hepatic expression of somatotropic

axis genes during pregnancy and lactation'. Journal of Dairy Science, 95 (7):3711-

3721.

O'Hara L, Scully S, Maillo V, Kelly AK, Duffy P, Carter F, Forde N, Rizos D,

Lonergan P (2012) 'Effect of follicular aspiration just before ovulation on corpus

luteum characteristics, circulating progesterone concentrations and uterine

receptivity in single-ovulating and superstimulated heifers'. Reproduction, 143

(5):673-682.

Mossa F, Walsh SW, Butler ST, Berry DP, Carter F, Lonergan P, Smith GW,

Ireland JJ, Evans AC (2012) 'Low numbers of ovarian follicles 3 mm in

diameter are associated with low fertility in dairy cows'. Journal of Dairy Science,

95 (5):2355-2361.





(5):2390-2396.

Hutchinson IA, Hennessy AA, Dewhurst RJ, Evans AC, Lonergan P, Butler ST

(2012) 'The effect of strategic supplementation with trans-10,cis-12 conjugated

linoleic acid on the milk production, estrous cycle characteristics, and

reproductive performance of lactating dairy cattle'. Journal of Dairy Science, 95

(5):2442-2451.

O'Shea LC, Mehta J, Lonergan P, Hensey C, Fair T (2012) 'Developmental

competence in oocytes and cumulus cells: candidate genes and networks'. Biology

of reproduction, 58 (2):88-101.

Richardson L, Hanrahan JP, Donovan A, Martí JI, Fair S, Evans AC, Lonergan P

(2012) 'Effect of site of deposition on the fertility of sheep inseminated with

frozen-thawed semen'. Animal Reproduction Science, 131 (3-4):160-164.

Matoba S, O'Hara L, Carter F, Kelly AK, Fair T, Rizos D, Lonergan P (2012) 'The

association between metabolic parameters and oocyte quality early and late

postpartum in Holstein dairy cows'. Journal of Dairy Science, 95 (3):1257-1266.

Cummins SB, Lonergan P, Evans AC, Berry DP, Evans RD, Butler ST (2012)

'Genetic merit for fertility traits in Holstein cows: I. Production characteristics and

reproductive efficiency in a pasture-based system'. Journal of Dairy Science, 95

(3):1310-1322.

Garcia-Herreros M, Aparicio IM, Rath D, Fair T, Lonergan P (2012) 'Differential

glycolytic and glycogenogenic transduction pathways in male and female bovine

embryos produced in vitro'. Reproduction, fertility, and development, 24 (2):344-

352.

Rizos D, Scully S, Kelly AK, Ealy AD, Moros R, Duffy P, Al Naib A, Forde N,

Lonergan P (2012) 'Effects of human chorionic gonadotrophin administration on

day 5 after oestrus on corpus luteum characteristics, circulating progesterone and

conceptus elongation in cattle'. Reproduction, fertility, and development, 24

(3):472-481.

Forde N, Lonergan P (2012) 'Transcriptomic analysis of the bovine endometrium:

What is required to establish uterine receptivity to implantation in cattle?'. The

Journal of reproduction and development, 58 (2):189-195.

Lonergan P; (2011) 'Influence of progesterone on oocyte quality and embryo

development in cows'. Theriogenology, 76 (9):1594-1601.





Richardson L, Hanrahan JP, O'Hara L, Donovan A, Fair S, O'Sullivan M,

Carrington SD, Lonergan P, Evans AC; (2011) 'Ewe breed differences in fertility

after cervical AI with frozen-thawed semen and associated differences in sperm

penetration and physicochemical properties of cervical mucus'. Animal

Reproduction Science, 129 (1-2):37-43.

Al Naib A, Ward F, Kelly AK, Wade M, Marti JI, Lonergan P; (2011) 'Effect of

duration of storage at ambient temperature on fertilizing ability and mucus

penetration ability of fresh bovine sperm'. Theriogenology, 76 (6):1070-1075.

Leal C, Mamo S, Fair T, Lonergan P; (2011) 'Gene Expression in Bovine Oocytes

and Cumulus Cells After Meiotic Inhibition with the Cyclin-Dependent Kinase

Inhibitor Butyrolactone I'. Reproduction in Domestic Animals .

Professor David MacHugh

Magee, David A., Taraktsoglou, Maria, Killick, Kate E., Nalpas, Nicolas C.,

Browne, John A., Park, Stephen D. E., Conlon, Kevin M., Lynn, David J.,

Hokamp, Karsten, Gordon, Stephen V., Gormley, Eamonn, MacHugh, David E.

(2012) 'Global gene expression and systems biology analysis of bovine monocyte-

derived macrophages in response to in vitro challenge with Mycobacterium bovis'.

PLoS ONE, 7 (2).

Eivers, S. S., McGivney, B. A., Gu, J., MacHugh, D. E., Katz, L. M., Hill, E. W.

(2012) 'PGC-1 alpha encoded by the PPARGC1A gene regulates oxidative energy

metabolism in equine skeletal muscle during exercise'. Animal Genetics, 43

(2):153-162.

MacHugh, David E., Taraktsoglou, Maria, Killick, Kate E., Nalpas, Nicolas C.,

Browne, John A., Park, Stephen D. E., Hokamp, Karsten, Gormley, Eamonn,

Magee, David A. (2012) 'Pan-genomic analysis of bovine monocyte-derived

macrophage gene expression in response to in vitro infection with Mycobacterium

avium subspecies paratuberculosis'. Veterinary Research, 43 .

Berkowicz, E. W., Magee, D. A., Berry, D. P., Sikora, K. M., Howard, D. J.,

Mullen, M. P., Evans, R. D., Spillane, C., MacHugh, D. E. (2012) 'Single

nucleotide polymorphisms in the imprinted bovine insulin-like growth factor 2

receptor gene (IGF2R) are associated with body size traits in Irish Holstein-

Friesian cattle'. Animal Genetics, 43 (1):81-87.


Kijas, James W., Lenstra, Johannes A., Hayes, Ben, Boitard, Simon, Porto Neto,

Laercio R., San Cristobal, Magali, Servin, Bertrand, McCulloch, Russell, Whan,

Vicki, Gietzen, Kimberly, Paiva, Samuel, Barendse, William, Ciani, Elena,

Raadsma, Herman, McEwan, John, Dalrymple, Brian, International Sheep

Genomics Consortium, Members (2012) 'Genome-wide analysis of the world's

sheep breeds reveals high levels of historic mixture and strong recent selection'.

PLoS Biology, 10 (2).

Magee, David A., Taraktsoglou, Maria, Killick, Kate E., Nalpas, Nicolas C.,

Browne, John A., Park, Stephen D. E., Conlon, Kevin M., Lynn, David J.,

Hokamp, Karsten, Gordon, Stephen V., Gormley, Eamonn, MacHugh, David E.

(2012) 'Global Gene Expression and Systems Biology Analysis of Bovine

Monocyte-Derived Macrophages in Response to In Vitro Challenge with

Mycobacterium bovis'. PLoS ONE, 7 (2).

Meade, Kieran G., O'Gorman, Grace M., Narciandi, Fernando, MacHugh, David

E., O'Farrelly, Cliona (2012) 'Functional characterisation of bovine interleukin 8

promoter haplotypes in vitro'. Molecular Immunology, 50 (1-2):108-116.

Bower, Mim A., McGivney, Beatrice A., Campana, Michael G., Gu, Jingjing,

Andersson, Lisa S., Barrett, Elizabeth, Davis, Catherine R., Mikko, Sofia, Stock,

Frauke, Voronkova, Valery, Bradley, Daniel G., Fahey, Alan G., Lindgren,

Gabriella, MacHugh, David E., Sulimova, Galina, Hill, Emmeline W. (2012) 'The

genetic origin and history of speed in the Thoroughbred racehorse'. Nature

Communications, 3 .

Hill, Emmeline W., Fonseca, Rita G., McGivney, Beatrice A., Gu, Jingjing,

MacHugh, David E., Katz, Lisa M. (2012) 'MSTN genotype (g.66493737C/T)

association with speed indices in Thoroughbred racehorses'. Journal of Applied

Physiology, 112 (1):86-90.

Mullen, Michael P., Creevey, Christopher J., Berry, Donagh P., McCabe, Matt S.,

Magee, David A., Howard, Dawn J., Killeen, Aideen P., Park, Stephen D.,

McGettigan, Paul A., Lucy, Matt C., MacHugh, David E., Waters, Sinead M.

(2012) 'Polymorphism discovery and allele frequency estimation using high-

throughput DNA sequencing of target-enriched pooled DNA samples'. BMC

Genomics, 13 .

Sheridan, Michael P., Browne, John A., MacHugh, David E., Costello, Eamon,

Gormley, Eamonn (2012) 'Impact of delayed processing of bovine peripheral

blood on differential gene expression'. Veterinary Immunology and

Immunopathology, 145 (1-2):199-205.

Killick, Kate E., Browne, John A., Park, Stephen D. E., Magee, David A., Martin,

Irene, Meade, Kieran G., Gordon, Stephen V., Gormley, Eamonn, O'Farrelly,

Cliona, Hokamp, Karsten, MacHugh, David E. (2011) 'Genome-wide

transcriptional profiling of peripheral blood leukocytes from cattle infected with

Mycobacterium bovis reveals suppression of host immune genes'. BMC

Genomics, 12 .

Dr Patricia Maguire

Steele BM, Harper MT, Smolenski AP, Alkazemi A, Poole AW, Fitzgerald DJ,

Maguire PB (2012) 'WNT-3a modulates platelet function by regulating small

GTPase activity'. FEBS Letters, 586 (16):2267-2276.


Professor Jonathan Malthouse

Petrillo T, O'Donohoe CA, Howe N, Malthouse JPG (2012) 'Importance of

tetrahedral intermediate formation in the catalytic mechanism of the serine

proteases chymotrypsin and subtilisin'. Biochemistry, 51 (31):6164-6170.

Ceruso M, Howe N, Malthouse JP; (2011) 'Mechanism of the binding of Z-L-

tryptophan and Z-L-phenylalanine to thermolysin and stromelysin-1 in aqueous

solutions'. Biochimica et biophysica acta, 1824 (2):303-310.

Dr Gethin McBean

McBean G J (2012) 'The transsulfuration pathway: a source of cysteine for

glutathione in astrocytes'. Amino Acids, 42 :199-205.

Dr Amanda McCann

Furlong F, Fitzpatrick P, Phelan S, Maguire A, McGrogan B, Prencipe M,

McGoldrick A, McGettigan P, Brennan D, Gallagher M, Sharon OToole S, Sheils

O, OGrady A, Kay EW, OLeary J, McCann A. (2012) 'Low MAD2 expression

associates with reduced progression free survival in patients with serous papillary

epithelial ovarian cancer'. Journal of Pathology, 226 (5):746-755.

Dr Margaret McGee

Bannon JH, O'Donovan DS, Kennelly SM, Mc Gee MM. (2012) 'The peptidyl

prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is

required for cytokinesis'. Cell cycle (Georgetown, Tex.), 11 (7):1340-1353.





Mac Fhearraigh S, Mc Gee MM (2011) 'Cyclin B1 interacts with the BH3-only

protein Bim and mediates its phosphorylation by Cdk1 during mitosis'. Cell cycle

(Georgetown, Tex.), 10 (22):3886-3896.

Professor Paul McLoughlin

Adamali H, Armstrong ME, McLaughlin AM, Cooke G, McKone E, Costello

CM, Gallagher CG, Leng L, Baugh JA, Fingerle-Rowson G, Bucala RJ,

McLoughlin P, Donnelly SC. (2012) 'Macrophage Migration Inhibitory Factor

Enzymatic Activity, Lung Inflammation and Cystic Fibrosis'. American Journal of

Respiratory and Critical Care Medicine .

Oliver KM, Lenihan CR, Bruning U, Cheong A, Laffey JG, McLoughlin P, Taylor

CT, Cummins EP; (2012) 'Hypercapnia induces cleavage and nuclear localization

of REL B giving insight into co2 sensing and signalling'. Journal of Biological

Chemistry .

Cahill E, Costello CM, Rowan SC, Harkin S, Howell K, Leonard MO, Southwood

M, Cummins EP, Fitzpatrick SF, Taylor CT, Morrell NW, Martin F, McLoughlin

P; (2012) 'Gremlin plays a key role in the pathogenesis of pulmonary

hypertension'. Circulation, 125 (7):920-930.

Cahill E, Rowan SC, Sands M, Banahan M, Ryan D, Howell K, McLoughlin P;

(2012) 'The pathophysiological basis of chronic hypoxic pulmonary hypertension






http://www.ncbi.nlm.nih.gov/pubmed/22592805

in the mouse: vasoconstrictor and structural mechanisms contribute equally'.

Experimental Physiology .

Dr Hilary McMahon

McMahon HEM (2012) 'Prion processing: a double-edged sword?'. Biochemical

Society Transactions, 40 (4):735-738.

Dr Tara McMorrow

Jennings P, Weiland C, Limonciel A, Bloch KM, Radford R, Aschauer L,

McMorrow T, Wilmes A, Pfaller W, Ahr HJ, Slattery C, Lock EA, Ryan MP,

Ellinger-Ziegelbauer H. (2012) 'Transcriptomic alterations induced by Ochratoxin

A in rat and human renal proximal tubular in vitro models and comparison to a rat

in vivo model'. Archives of Toxicology, 86 (4):571-589.

Radford R, Slattery C, Jennings P, Blaque O, Pfaller W, Gmuender H, Van Delft

J, Ryan MP, McMorrow T. (2012) 'Carcinogens induce loss of the primary cilium

in human renal proximal tubular epithelial cells independently of effects on the

cell cycle'. American Journal of Physiology-Renal Physiology, 302 (8):905-916.

Cassidy H, Radford R, Slyne J, O'Connell S, Slattery C, Ryan MP, McMorrow T

(2012) 'The role of MAPK in drug-induced kidney injury'. Journal of Signal

Transduction, 2012 .

O'Connell S, Tuite N, Slattery C, Ryan MP, McMorrow T. (2012) 'Cyclosporine

A-induced oxidative stress in human renal mesangial cells: a role for ERK 1/2

MAPK signaling'. Toxicological sciences : an official journal of the Society of

Toxicology, 126 (1):101-113.

O'Connell S, Slattery C, Ryan MP, McMorrow T. (2012) 'Sirolimus enhances

cyclosporine a-induced cytotoxicity in human renal glomerular mesangial cells'.

Journal of transplantation, 2012 .

Martin-Martin N, Dan Q, Amoozadeh Y, Waheed F, McMorrow T, Ryan MP,

Szaszi K. (2012) 'RhoA and Rho kinase mediate cyclosporine A and sirolimus-

induced barrier tightening in renal proximal tubular cells'. International Journal of

Biochemistry & Cell Biology, 44 (1):178-188.

Martin-Martin N, Slattery C, McMorrow T, Ryan MP. (2011) 'TGF-β1 mediates

sirolimus and cyclosporine A-induced alteration of barrier function in renal

epithelial cells via a noncanonical ERK1/2 signaling pathway'. American Journal

of Physiology-Renal Physiology, 301 (6):1281-1292.

Ellis JK, Athersuch TJ, Cavill R, Radford R, Slattery C, McMorrow T, Ryan MP,

Ebbels TMD, Keun H (2011) 'Metabolic Response to Low Level Toxicant

Exposure in a Novel Renal Tubule'. Molecular BioSystems, 7 (1):247-257.

Professor Walter McNicholas

Kent BD, McNicholas WT, Verbraecken J (2012) 'Disturbed sleep and COPD

outcomes: cart meets horse'. Sleep, 13 (5):453-454.

Parati G, Lombardi C, Hedner J, Bonsignore MR, Grote L, Tkacova R, Levy P,

Riha R, Bassetti C, Narkiewicz K, Mancia G, McNicholas WT (2012) 'Position

paper on the management of patients with obstructive sleep apnea and

hypertension: joint recommendations by the European Society of Hypertension,

by the European Respiratory Society and by the members of European COST

(COoperation in Scientific and Technological research) ACTION B26 on




obstructive sleep apnea'. J HYPERTENS, 30 (4):633-646.

Bonsignore MR, McNicholas WT, Montserrat JM, Eckel J (2012) 'Adipose tissue

in obesity and obstructive sleep apnoea'. EUR RESPIR J, 39 (3):746-767.

Kent BD, Ryan S, McNicholas WT (2011) 'Obstructive sleep apnea and

inflammation: relationship to cardiovascular co-morbidity'. Respiratory

physiology & neurobiology, 178 (3):475-481.

Hedner J, Grote L, Bonsignore M, McNicholas W, Lavie P, Parati G, Sliwinski P,

Barbé F, De Backer W, Escourrou P, Fietze I, Kvamme JA, Lombardi C, Marrone

O, Masa JF, Montserrat JM, Penzel T, Pretl M, Riha R, Rodenstein D, Saaresranta

T, Schulz R, Tkacova R, Varoneckas G, Vitols A, Vrints H, Zielinski J (2011)

'The European Sleep Apnoea Database (ESADA): report from 22 European sleep

laboratories'. EUR RESPIR J, 38 (3):635-642.

De Backer W, Simonds AK, Horn V, Andreas S, Bonsignore M, Calverley P,

Donic V, Lévy P, Mitchell S, McNicholas WT, Morrell M, Randerath W, Riha

RL, Trang H, Verbraecken J, Palange P (2011) 'Sleep HERMES: a European

training project for respiratory sleep medicine'. EUR RESPIR J, 38 (3):496-497.

Professor Wim Meijer

Garcia MS, Carvalho D, Zlydareva O, Muldoon C, Masterson BF, O'Grady MJ,

Meijer,WG, O'Sullivan JJ, O'Hare GMP (2012) 'An agent-based wireless sensor

network for water quality data collection'. Lecture Notes in Computer Science,

7656 .

Dr Anika Mostaert

Brennan, L., Blanco Fernandez, A., Mostaert, A.S. and Owende, P. (2012)

'Enhancement of BODIPY(505/515) lipid fluorescence method for applications in

biofuel-directed microalgae production'. Journal of Microbiological Methods, 90

(2):137-143.

Keane, P.N., Hovgaard, M., Mostaert, A.S. and Jarvis, S.P. (2012) 'Asymmetric

spatula heads combined with lateral forces provide a mechanism for controlling

the adhesive attachment of a range of spider species'. Journal of Adhesion Science

and Technology, Online .

Professor Grace V T Mulcahy

Halov᠄, Mulcahy G, Rafter P, Turčekov , Grant T, de Waal T. (2012) 'Toxoplasma

gondii in Ireland: Seroprevalence and Novel Molecular Detection Method in

Sheep, Pigs, Deer and Chickens'. Zoonoses and Public Health .

Claridge J, Diggle P, McCann CM, Mulcahy G, Flynn R, McNair J, Strain S,

Welsh M, Baylis M, Williams DJ. (2012) 'Fasciola hepatica is associated with the

failure to detect bovine tuberculosis in dairy cattle'. Nature Communications, 22

(3).

Buffoni, L Martinez-Moreno, F J Zafra, R Mendes, R E Perez-Ecija, A Sekiya, M

Mulcahy, G Perez, J Martinez-Moreno, A (2012) 'Humoral immune response in

goats immunised with cathepsin L1, peroxiredoxin and Sm14 antigen and

experimentally challenged with Fasciola hepatica'. Veterinary Parasitology .

ZINTL, A., EZZATY-MIRASHEMI, M., CHALMERS, R.M., ELWIN, K.,

MULCAHY, G., LUCY, F.E., DE WAAL, T.; (2011) 'Longitudinal and spatial

distribution of GP60 subtypes in human cryptosporidiosis cases in Ireland'.




http://dx.doi.org/10.1016/j.mimet.2012.03.020

http://dx.doi.org/10.1080/01694243.2012.691800

Epidemiology and infection, 139 :1945-1955.

Dr Evelyn Murphy

Mohan HM, Aherne CM, Rogers AC, Baird AW, Winter DC, Murphy EP. (2012)

'The role of NR4A orphan nuclear receptors in cancer'. Clinical Cancer Research,

18 (12):3223-3228.

Marzaioli V, McMorrow JP, Angerer H, Gilmore A, Crean D, Zocco D, Rooney

P, Veale D, Fearon U, Gogarty M, McEvoy AN, Stradner M and Murphy EP.

(2012) 'Histamine contributes to increased RANKL/OPG ratio through altered

NR4A activity in human chondrocyte cells'. Arthritis and Rheumatism, 64

(10):3290-3301.

Mix KS, McMahon K, McMorrow JP, Walkenhorst D , Smyth AM, Petrella BL,

Gogarty M, Fearon U, Veale D, Attur MG, Abramson SB and Murphy EP.; (2012)

'Orphan nuclear receptor NR4A2 induces synoviocyte proliferation, invasion, and

MMP-13 transcription'. Arthritis and Rheumatism, 64 (7):2126-21236.

Dr Keith Murphy

Scully D, Fedriani R, Desouza IE, Murphy KJ, Regan CM (2012) 'Regional

dissociation of paradigm-specific synapse remodeling during memory

consolidation in the adult rat dentate gyrus'. Neuroscience, 209 :74-83.

Monopoli MP, Raghnaill MN, Loscher JS, O'Sullivan NC, Pangalos MN, Ring

RH, von Schack D, Dunn MJ, Regan CM, Pennington S, Murphy KJ; (2011)

'Temporal proteomic profile of memory consolidation in the rat hippocampal

dentate gyrus'. Proteomics, 11 (21):4189-4201.

Dr Jarlath Nally

O. Condell, A, Sheridan, K. Power, R. Bonilla-Santiago, K. Seargent, J. Renaut,

K. Burgess, S. Fanning, J.E. Nally (2012) 'Comparative proteomic analysis of

Salmonella tolerance to the biocide active agent triclosan'. Journal of Proteomics,

75 (14):4505-4519.

O'Donovan J., Proctor A., Gutierrez J., Worrall S., Nally J., Marques P. X., Brady

C., McElroy M., Sammin D., Buxton D., Maley S. , Bassett H., Markey B.; (2012)

'Distribution of lesions in ovine foetal brains following experimental infection of

pregnant sheep with Toxoplasma gondii'. Veterinary Pathology .

Marques, P.X., O' Donovan, J., Williams, E.J., Gutierrez, J., Worrall, S., McElroy,

M., Proctor, A., Brady, C., Sammin, D., Bassett, H., Buxton, D., Maley, S.,

Markey, B.K., Nally, J.E; (2012) 'Detection of Toxoplasma gondii antigens

reactive with antibodies from serum, amniotic, and allantoic fluids from

experimentally infected pregnant ewes'. Veterinary Parasitology .

Jarlath E. Nally, Avril M. Monahan, Ian S. Miller, Ruben Bonilla-Santiago,

Puneet Souda, and Julian P. Whitelegge; (2011) 'Comparative Proteomic Analysis

of Differentially Expressed Proteins in the Urine of Reservoir Hosts of

Leptospirosis'. PLoS ONE .

Dr Jens Erik Nielsen








http://dx.doi.org/10.1017/S0950268810002992



Dr Peter O'Brien

Ramery E, Papakonstantinou S, Pinilla M, McAllister H, Jahns H, Gallagher B,

OBrien PJ (2012) 'Bacterial cholangiohepatitis in a dog'. Canadian Veterinary

Journal, 53 :412-418.

Professor Ronan O'Connell

OReilly E, Burke JP, OConnell PR (2012) 'LAPAROSCOPIC VERSUS OPEN

APPROACH FOR PRIMARY, UNILATERAL, INGUINAL HERNIA: A

META-ANALYSIS OF OUTCOMES'. Annals of Surgery, 255 :846-853.

Buffini M, O'Halloran KD, O'Herlihy C, O'Connell PR, Jones JF (2012)

'Comparison of the motor discharge to the voluntary sphincters of continence in

the rat'. Neurogastroenterology and motility : the official journal of the European

Gastrointestinal Motility Society, 24 (4):1-84.

Griffin KM, O'Herlihy C, O'Connell PR, Jones JF (2012) 'Combined ischemic and

neuropathic insult to the anal canal in an animal model of obstetric-related

trauma'. Diseases of the Colon &Amp; Rectum, 55 (1):32-41.

Griffin KM, O'Herlihy C, O'Connell PR, Jones JF (2012) 'COMBINED

ISCHEMIC AND NEUROPATHIC INSULT TO THE ANAL CANAL IN AN

ANIMAL MODEL OF OBSTETRIC-RELATED TRAUMA'. Diseases of the

colon and rectum, 55 :32-41.

Kavanagh DO, Quinlan DM, Armstrong JG, Hyland JM, O'Connell PR, Winter

DC (2012) 'MANAGEMENT OF SYNCHRONOUS RECTAL AND PROSTATE

CANCER'. International Journal of Colorectal Disease .

Buffini, M., OHalloran K.D., OHerlihy, C., OConnell, P.R., Jones, J.F.X (2012)

'COMPARISON OF THE MOTOR DISCHARGE TO THE VOLUNTARY

SPHINCTERS OF CONTINENCE IN THE RAT'. Neurogastroenterology and

Motility, 24 :e175-e184.

Kennelly RP, Heeney A, White A, Fennelly D, Sheahan K, Hyland JM, O'Connell

PR, Winter DC. (2012) 'A PROSPECTIVE ANALYSIS OF PATIENT

OUTCOME FOLLOWING'. International Journal of Colorectal Disease, 27

:759-764.

Maeda Y, O'Connell PR, Matzel KE, Laurberg S. (2012) 'SACRAL NERVE

STIMULATION FOR FECAL INCONTINENCE: AT A CROSSROAD AND

FUTURE CHALLENGES'. Diseases of the colon and rectum, 55 :621-624.

Smith F, Chang KH, Sheahan K, Hyland JH, OConnell PR, Winter DC (2012)

'THE SURGICAL SIGNIFICANCE OF RESIDUAL MUCOSAL

ABNORMALITIES IN RECTAL CANCER FOLLOWING NEOADJUVANT

CHEMORADIOTHERAPY'. British Journal of Surgery, 99 :993-1001.

Mohan HM, McDermott S, Fenelon L, Fearon NM, O'Connell PR, Oon SF, Burke

J, Keane E, Shields C, Winter DC (2012) 'PLASTIC WOUND RETRACTORS

AS BACTERIOLOGICAL BARRIERS IN GASTROINTESTINAL SURGERY:

A PROSPECTIVE MULTI-INSTITUTIONAL TRIAL'. Journal of Hospital

Infection .

Martin ST, Heeney A, Pierce C, O'Connell PR, Hyland JM, Winter DC.; (2011)

'Use of an electrothermal bipolar sealing device in ligation of major mesenteric



vessels during laparoscopic colorectal resection'. Techniques in coloproctology, 15

(3):285-289.

Rowan F, Coffey JC, Oʼconnell PR, Docherty NG, Murphy M, Murphy TB.;

(2011) 'Ileal Pouch Microbial Diversity'. Annals of Surgery .

Dr John O'Connor

OConnor JJ, Lowry JP (2012) 'A comparison of the effects of the dopamine

partial agonists aripiprazole and 3-PPP with quinpirole on stimulated dopamine

release in the rat striatum: studies using fast cyclic voltammetry'. European

Journal of Pharmacology, 686 :60-65.

Dr Kevin O'Connor

Narancic T, Nikodinovic J, Kenny S, Vasiljevic B and K O'Connor. (2012)

'Metabolic versatility of Gram-positive microbial isolates from contaminated river

sediments'. Journal of Hazardous Materials, 215-216 :243-251.

Kenny ST, Nikodinovic Runic J, Kaminsky W, Woods T, Babu RP, and O'Connor

KE. (2012) 'Development of a bioprocess to convert PET derived terephthalic acid

and biodiesel derived glycerol to medium chain length polyhydroxyalkanoate'.

Applied Microbiology and Biotechnology, 95 (3):623-633.

Narancic T, Kenny S, Lidija D, Vasiljevic B, O'Connor KE, Nikodinovic-Runic J

(2012) 'Medium chain length polyhydroxyalkanoate production by newly isolated

Pseudomonas sp. TN301 from a wide range of poly- and monoaromatic

hydrocarbons'. Journal of Applied Microbiology, 113 :508-520.

Nikodinovic-Runic J, Coulombel L, Francuski D, Sharma ND, Boyd DR, More

O'Ferrall R and O'Connor KE (2012) 'The oxidation of alkylaryl sulfides and

benzo[b]thiophenes by Escherichia coli cells expressing wild-type and engineered

styrene monooxygenase from Pseudomonas putida CA-3'. Applied Microbiology

and Biotechnology .

Boyd DR, Sharma ND, McMurray B, Haughey SA, Allen CCR,Hamilton JTG,

McRoberts WC,More O'Ferrall RA, Nikodinovic-Runic J, Coulombel LA and

O'Connor KE. (2012) 'Bacterial dioxygenase- and monooxygenase-catalysed

sulfoxidation of benzo[b]thiophenes'. Org Biomol Chem, 10 :782-790.

Dr Jim O'Gara

Stallard CP, McDonnell KA, Onayemi OD, O'Gara JP, Dowling DP (2012)

'Evaluation of protein adsorption on atmospheric plasma deposited coatings

exhibiting superhydrophilic to superhydrophobic properties'. Biointerphases, 7

:31-39.

Pozzi C, Waters EM, Rudkin JK, Schaeffer CR, Lohan AJ, Tong P, Loftus BJ,

Pier GB, Fey PD, Massey RC and O'Gara JP (2012) 'Methicillin Resistance Alters

the Biofilm Phenotype and Attenuates Virulence in Staphylococcus aureus

Device-Associated Infections'. PLoS Pathogens, 8 (4):e-1002626.

Rudkin JK, Edwards AM, Bowden MG, Brown EL, Pozzi C, Waters E, Chan W,

Williams P, O'Gara J P and Massey RC (2012) 'Methicillin Resistance Reduces

the Virulence of Healthcare-Associated Methicillin-Resistant Staphylococcus

aureus by Interfering With the agr Quorum Sensing System'. Journal of Infectious

Diseases, 205 (5):798-806.

Stevens NT, Greene CM, O'Gara JP, Bayston R, Sattar MT, Farrell M and




Humphreys H (2012) 'Ventriculoperitoneal shunt-related infections caused by

Staphylococcus epidermidis: pathogenesis and implications for treatment'. British

Journal of Neurosurgery, Epub ahead of print .

Galvin S, Boyle M, Russell R, Coleman D, Creamer E, O'Gara JP, DFitzgerald-

Hughes D, Humphreys H (2012) 'A practical evaluation of vaporised hydrogen

peroxide, CITROX and ECASOL in the decontamination of an enclosed area'.

Journal of Hospital Infection, 80 (1):67-70.

Professor Donal O'Shea





O'Shea DF; (2012) 'Discussion Addendum for Suzuki-Miyaura Cross-Coupling:

Preparation of 2'-Vinylacetanilide'. Organic Synthesis .

Professor Stefan Oscarson

A. Wellens, M. Lahmann, M. Touaibia, H. de Greve, S. Oscarson, R. Roy, H.

Remaut, J. Bouckaert (2012) 'Tyrosine as an entropic adapter in the mannose-

binding site of the bacterial adhesion FimH'. Biochemistry, 51 :4790-4799.

D. Safari, M. Marradi, F. Chiodo, H. A. T. Dekker, Y. Shan, R. Adamo, S.

Oscarson, G. T. Tijkers, M. Lahmann, J. P. Kamerling, S. Penades and H. Snippe

(2012) 'A fully synthetic carbohydrate vaccine candidate based on gold

nanoparticles'. Nanomedicine, 7 :651-662.

Dr Francesca Paradisi

Hackenberg, F; Lally, G; Mller-Bunz, H; Paradisi, F; Quaglia, D; Streciwilk, W;

Tacke, M (2012) 'Synthesis and biological evaluation of N-heterocyclic carbene-

silver(I) acetate complexes derived from 4,5-ditolyl-imidazole'. Inorganica

Chimica Acta .

Hackenberg, F. et al.; (2012) 'Novel non-symmetrically p-benzyl-substituted

(benz)imidazole N-heterocyclic carbene-silver(I) acetate complexes - synthesis

and biological evaluation'. International Journal of Inorganic Chemistry, 2012

:Article ID 12154-13 pages.

Lestini, E; Robertson, K; Murphy, CD; Paradisi, F (2012) 'An alternative mild

route to the synthesis of 4-methylenecyclohex-2-enone, a key moiety of the

anticancer compounds ottelione A and B'. Synthetic Communications, 42 :1864-

1876.

Timpson, L; Alsafadi, D; Mac Donnchadha, C; Liddell, S; Sharkey, MA; Paradisi,

F (2012) 'Characterization of alcohol dehydrogenase (ADH12) from Haloarcula

marismortui, an extreme halophile from the Dead Sea'. Extremophiles, 16 :57-66.

Devereux, S. et al.; (2011) 'Isolation and Characterisation of Recovered Starch

from Industrial Wastewater'. Journal of Polymers and the Environment, 19

(4):971-979.

Pandurangan, K. et al.; (2011) 'Design, Synthesis and Structure of Novel para-

quinones and their Antibacterial Activity'. Chemical Biology and Drug Design, 78

:787-799.




Professor William Powderly

Chasela CS, Wall P, Drobeniuc J, King CC, Teshale E, Hosseinipour MC,

Ellington SR, Codd M, Jamieson DJ, Knight RJ, Fitzpatrick P, Kourtis AP,

Hoffman IF, Kayira D, Mumba N, Kamwendo DD, Martinson F, Powderly W,

van der Horst C, Kamili S (2012) 'Prevalence of hepatitis C virus infection among

human immunodeficiency virus-1-infected pregnant women in Malawi: The BAN

study'. Journal of Clinical Virology .

Powderly WG (2012) 'Osteoporosis and Bone Health in HIV'. AIDS .

Marcus KA, Sorbello A, Truffa M, Williams J, Raine JM, Powderly WG (2012)

'Current advances in pharmacovigilance in the USA and Europe: meeting the

challenges of safety monitoring in HIV'. Current Opinion in Infectious Diseases, 7

:292-298.

De Gascun CF, Waters A, Regan CM, O'Halloran J, Farrell G, Coughlan S,

Bergin C, Powderly WG, Hall WW (2012) 'Human Immunodeficiency Virus

Type 1 in Ireland: Phylogenetic Evidence for Risk Group-Specific Subepidemics'.

AIDS Research and Human Retroviruses .

De Gascun CF, Waters A, Regan C, O'Halloran J, Farrell G, Coughlan S, Bergin

C, Powderly WG, Hall WW (2012) 'Documented prevalence of HIV type 1

antiretroviral transmitted drug resistance in Ireland from 2004 to 2008'. AIDS

Research and Human Retroviruses, 28 (3):276-281.

Professor Ciaran Regan

Scully D, Fedriani R, DeSouza IEJ, Murphy KJ, Regan CM (2012) 'Regional

dissociation of paradigm-specific synapse remodelling during memory

consolidation in the adult rat dentate gyrus'. Neuroscience, 209 :74-83.

Freir DB, Fedriani R, Scully D, Smith IM, Selkoe DJ, Walsh DM, Regan CM

(2011) 'Aβ oligomers inhibit synapse remodelling necessary for memory

consolidation'. Neurobiology of Aging, 32 (12):2211-2218.

Monopoli MP, Nic Raghnaill M, Loscher JS, O'Sullivan NC, Pangalos MN, Ring

RH, Von Schack D, Dunn MJ, Regan CM, Pennington S, Murphy KJ (2011)

'Temporal proteomic profile of memory consolidation in the rat hippocampal

dentate gyrus'. Proteomics, 11 (21):4189-4200.

Professor Helen Roche

Phillips CM, Kesse-Guyot E, Ahluwalia N, McManus R, Hercberg S, Lairon D,

Planells R, Roche HM. (2012) 'Dietary fat, abdominal obesity and smoking

modulate the relationship between plasma complement component 3

concentrations and metabolic syndrome risk'. Atherosclerosis .

Rungapamestry V, McMonagle J, Reynolds C, Rucklidge G, Reid M, Duncan G,

Ross K, Horgan G, Toomey S, Moloney AP, Roos Bd, Roche HM. (2012) 'Inter-

organ proteomic analysis reveals insights into the molecular mechanisms

underlying the anti-diabetic effects of cis-9, trans-11-conjugated linoleic acid in

ob/ob mice'. Proteomics, 12 (3):461-476.

Cruz-Teno C, Pérez-Martínez P, Delgado-Lista J, Yubero-Serrano EM, García-

Ríos A, Marín C, Gómez P, Jiménez-Gómez Y, Camargo A, Rodríguez-Cantalejo

F, Malagón MM, Pérez-Jiménez F, Roche HM, López-Miranda J. (2012) 'Dietary

fat modifies the postprandial inflammatory state in subjects with metabolic




syndrome: the LIPGENE study'. Molecular Nutrition and Food Research, 56

(6):854-865.

Börgeson E, McGillicuddy FC, Harford KA, Corrigan N, Higgins DF, Maderna P,

Roche HM, Godson C. (2012) 'Lipoxin A4 attenuates adipose inflammation'.

FASEB Journal, 26 (10):4287-4294.

Reynolds CM, McGillicuddy FC, Harford KA, Finucane OM, Mills KH, Roche

HM. (2012) 'Dietary saturated fatty acids prime the NLRP3 inflammasome via

TLR4 in dendritic cells-implications for diet-induced insulin resistance'.

Molecular Nutrition and Food Research, 56 (8):1212-1222.

Garcia-Rios A, Perez-Martinez P, Delgado-Lista J, Phillips CM, Gjelstad IM,

Wright JW, Karlström B, Kiec-Wilk B, van Hees AM, Helal O, Polus A, Defoort

C, Riserus U, Blaak EE, Lovegrove JA, Drevon CA, Roche HM, Lopez-Miranda

J. (2012) 'A Period 2 genetic variant interacts with plasma SFA to modify plasma

lipid concentrations in adults with metabolic syndrome'. Journal of Nutrition, 142

(7):1213-1218.

McAllan L, Cotter PD, Roche HM, Korpela R, Nilaweera KN. (2012) 'Impact of

leucine on energy balance'. Journal of Physiology, .

Phillips CM, Kesse-Guyot E, McManus R, Hercberg S, Lairon D, Planells R,

Roche HM. (2012) 'High dietary saturated fat intake accentuates obesity risk

associated with the fat mass and obesity-associated gene in adults'. Journal of

Nutrition, 142 (5):824-831.

Delgado-Lista J, Perez-Martinez P, Garcia-Rios A, Phillips CM, Hall W, Gjelstad

IM, Lairon D, Saris W, Kieć-Wilk B, Karlström B, Drevon CA, Defoort C, Blaak

EE, Dembinska-Kieć A, Risérus U, Lovegrove JA, Roche HM, Lopez-Miranda J.

(2012) 'A gene variation (rs12691) in the CCAT/enhancer binding protein α

modulates glucose metabolism in metabolic syndrome'. Nutrition Metabolism and

Cardiovascular Diseases, .

Perez-Martinez P, Delgado-Lista J, Garcia-Rios A, Tierney AC, Gulseth HL,

Williams CM, Karlström B, Kieć-Wilk B, Blaak EE, Helal O, Saris WH, Defoort

C, Drevon CA, Lovegrove JA, Dembinska-Kieć A, Riserus U, Roche HM, Lopez-

Miranda J. (2012) 'Insulin receptor substrate-2 gene variants in subjects with

metabolic syndrome: association with plasma monounsaturated and n-3

polyunsaturated fatty acid levels and insulin resistance'. Molecular Nutrition and

Food Research, 56 (2):309-315.

Camargo A, Rangel- Zúñiga OA, Peña-Orihuela P, Marín C, Pérez-Martínez P,

Delgado-Lista J, Gutierrez-Mariscal FM, Malagón MM, Roche HM, Tinahones

FJ, Lopez-Miranda J. (2012) 'Postprandial changes in the proteome are modulated

by dietary fat in patients with metabolic syndrome'. Journal of Nutritional

Biochemistry, .

Perez-Martinez P, Perez-Caballero AI, Garcia-Rios A, Yubero-Serrano EM,

Camargo A, Gomez-Luna MJ, Marin C, Gomez-Luna P, Dembinska-Kiec A,

Rodriguez-Cantalejo F, Tinahones FJ, Roche HM, Perez-Jimenez F, Lopez-

Miranda J, Delgado-Lista J. (2012) 'Effects of rs7903146 Variation in the Tcf7l2

Gene in the Lipid Metabolism of Three Different Populations'. PLoS ONE, 7 (8).

Finucane OM, Reynolds CM, McGillicuddy FC, Roche HM. (2012) 'Insights into

the role of macrophage migration inhibitory factor in obesity and insulin

resistance'. Proceedings of the Nutrition Society, .

McGillicuddy FC, Roche HM. (2012) 'Nutritional status, genetic susceptibility,

and insulin resistance--important precedents to atherosclerosis'. Molecular

Nutrition and Food Research, 56 (7):1173-1184.

Phillips CM, Tierney AC, Perez-Martinez P, Defoort C, Blaak EE, Gjelstad IM,

Lopez-Miranda J, Kiec-Klimczak M, Malczewska-Malec M, Drevon CA, Hall W,

Lovegrove JA, Karlstrom B, Risérus U, Roche HM. (2012) 'Obesity and Body Fat

Classification in the Metabolic Syndrome: Impact on Cardiometabolic Risk

Metabotype'. Obesity, .

Phelan N, O'Connor A, Kyaw Tun T, Correia N, Boran G, Roche H, Gibney J.

(2012) 'Leukocytosis in women with polycystic ovary syndrome (PCOS) is

incompletely explained by obesity and insulin resistance'. Clinical Endocrinology,

.

Meneses ME, Camargo A, Perez-Martinez P, Delgado-Lista J, Cruz-Teno C,

Jimenez-Gomez Y, Paniagua JA, Gutierrez-Mariscal FM, Tinahones FJ, Vidal-

Puig A, Roche HM, Perez-Jimenez F, Malagon MM, Lopez-Miranda J. (2012)

'Postprandial inflammatory response in adipose tissue of patients with metabolic

syndrome after the intake of different dietary models'. Molecular Nutrition and

Food Research, 55 (12):1759-1770.

Oliver E, McGillicuddy FC, Harford KA, Reynolds CM, Phillips CM, Ferguson

JF, Roche HM. (2012) 'Docosahexaenoic acid attenuates macrophage-induced

inflammation and improves insulin sensitivity in adipocytes-specific differential

effects between LC n-3 PUFA'. Proceedings of the Nutrition Society, 23 (9):1192-

1200.

Morris C, O'Grada C, Ryan M, Roche HM, Gibney MJ, Gibney ER, Brennan L.

(2012) 'The relationship between BMI and metabolomic profiles: a focus on

amino acids'. Proceedings of the Nutrition Society, :1-11.

Morine MJ, Toomey S, McGillicuddy FC, Reynolds CM, Power KA, Browne JA,

Loscher C, Mills KH, Roche HM (2012) 'Network analysis of adipose tissue gene

expression highlights altered metabolic and regulatory transcriptomic activity in

high-fat-diet-fed IL-1RI knockout mice'. The Journal of nutrition .

Reynolds CM, Toomey S, McBride R, McMonagle J, Morine MJ, Belton O,

Moloney AP, Roche HM (2012) 'Divergent effects of a CLA-enriched beef diet on

metabolic health in ApoE(-/-) and ob/ob mice'. Journal of Nutritional

Biochemistry, Epub ahead of print .

Brennan EP, Morine MJ, Walsh DW, Roxburgh SA, Lindenmeyer MT, Brazil DP,

Gaora PO, Roche HM, Sadlier DM, Cohen CD, Godson C, Martin F (2012) 'Next-

generation sequencing identifies TGF-β1-associated gene expression profiles in

renal epithelial cells reiterated in human diabetic nephropathy'. Biochimica et

biophysica acta, 1822 (4):589-599.

Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua

JA, Gołąbek-Leszczyñska I, Defoort C, Williams CM, Karlström B, Vessby B,

Dembinska-Kiec A, López-Miranda J, Blaak EE, Drevon CA, Gibney MJ,

Lovegrove JA, Roche HM (2011) 'Effects of dietary fat modification on insulin

sensitivity and on other risk factors of the metabolic syndrome--LIPGENE: a

European randomized dietary intervention study'. International Journal of

Obesity, 35 (6):800-809.

Professor Pauline Rudd


Saldova, R.,Fan, Y.,Fitzpatrick, J. M.,Watson, R. W.,Rudd, P. M.; (2011) 'Core

fucosylation and {alpha}2-3 sialylation in serum N-glycome is significantly

increased in prostate cancer comparing to benign prostate hyperplasia'.

Glycobiology, 21 (1).

Professor Denis Shields

Norris, R; Casey, F; FitzGerald, RJ; Shields, D; Mooney C; (2012) 'Predictive

modelling of angiotensin converting enzyme inhibitory dipeptides'. Food

Chemistry, 133 (4):1349-1354.

Mooney C, Pollastri G, Shields DC, Haslam NJ; (2011) 'Prediction of short linear

protein binding regions'. Journal of molecular biology .

Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC,

Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T,

Bolshakova N, Bolton PF, Bourgeron T, Brennan S, Cali P, Correia C, Corsello C,

Coutanche M, Dawson G, de Jonge M, Delorme R, Duketis E, Duque F, Estes A,

Farrar P, Fernandez BA, Folstein SE, Foley S, Fombonne E, Freitag CM, Gilbert

J, Gillberg C, Glessner JT, Green J, Guter SJ, Hakonarson H, Holt R, Hughes G,

Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Lamb JA, Leboyer M, Le

Couteur A, Leventhal BL, Lord C, Lund SC, Maestrini E, Mantoulan C, Marshall

CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A,

Miller J, Minopoli F, Mirza GK, Munson J, Nelson SF, Nygren G, Oliveira G,

Pagnamenta AT, Papanikolaou K, Parr JR, Parrini B, Pickles A, Pinto D, Piven J,

Posey DJ, Poustka A, Poustka F, Ragoussis J, Roge B, Rutter ML, Sequeira AF,

Soorya L, Sousa I, Sykes N, Stoppioni V, Tancredi R, Tauber M, Thompson AP,

Thomson S, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Vorstman JA,

Wallace S, Wang K, Wassink TH, White K, Wing K, Wittemeyer K, Yaspan BL,

Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H,

Cuccaro ML, Geschwind DH, Haines JL, Hallmayer J, Monaco AP, Nurnberger JI

Jr, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P,

Vieland VJ, Wijsman EM, Green A, Gill M, Gallagher L, Vicente A, Ennis S.;

(2011) 'A novel approach of homozygous haplotype sharing identifies candidate

genes in autism spectrum disorder'. Human Genetics .

Professor Jeremy Simpson

Simpson, J.C., Joggerst, B., Laketa, V., Verissimo, F., Cetin, C., Erfle, H., Bexiga,

M.G., Singan, V.R., Heriche, J.K., Neumann, B., Mateos, A., Blake, J., Bechtel,

S., Benes, V., Wiemann, S., Ellenberg, J. and Pepperkok, R. (2012) 'Genome-wide

RNAi screening identifies human proteins with a regulatory function in the early

secretory pathway'. Nature Cell Biology, 14:764-774 .

Singan, V.R., Handzic, K., Curran, K.M. and Simpson, J.C. (2012) 'A method for

improved clustering and classification of microscopy images using quantitative

co-localization coefficients'. BMC research notes, 5 (1):281.1-281.5.

Sandin, P., Fitpatrick, L.W., Simpson, J.C. and Dawson, K.A. (2012) 'High-Speed

Imaging of Rab Family Small GTPases Reveals Rare Events in Nanoparticle

Trafficking in Living Cells'. Acs Nano, 6 (2):1513-1521.

Bexiga, M.G., Varela, J.A., Wang, F., Fenaroli, F., Salvati, A., Lynch, I.,

Simpson, J.C. and Dawson, K.A. (2011) 'Cationic nanoparticles induce caspase 3-,

7- and 9-mediated cytotoxicity in a human astrocytoma cell line'. Nanotoxicology,

5 (4):557-567.



http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20861084http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20861084


http://dx.doi.org/10.1038/ncb2510

http://www.ncbi.nlm.nih.gov/pubmed/22681635

http://dx.doi.org/10.1021/nn204448x

http://dx.doi.org/10.3109/17435390.2010.539713

Singan, V.R., Jones, T.R., Curran, K.M. and Simpson, J.C. (2011) 'Dual channel

rank-based intensity weighting for quantitative co-localization of microscopy

images'. BMC Bioinformatics, 12:407 .

Moore, H.M., Bai, B., Boisvert, F.M., Latonen, L., Rantanen, V., Simpson, J.C.,

Pepperkok, R., Lamond, A.I. and Laiho, M. (2011) 'Quantitative Proteomics and

Dynamic Imaging of the Nucleolus Reveal Distinct Responses to UV and Ionizing

Radiation'. Molecular & Cellular Proteomics, 10, M111.009241 .

Dr Albert Smolenski

Steele BM, Harper MT, Smolenski AP, Alkazemi N, Poole AW, Fitzgerald DJ,

Maguire PB. (2012) 'WNT-3a modulates platelet function by regulating small

GTPase activity'. FEBS Letters, 586 (16):2267-2272.

Gegenbauer, K., Elia, G., Blanco-Fernandez, A and Smolenski, A.; (2012)

'Regulator of G-protein signaling protein 18 integrates activating and inhibitory

signaling in platelets'. Blood, 119 (16):3799-3807.

Smolenski A; (2011) 'Novel roles of cAMP/cGMP dependent signaling in

platelets'. Journal of Thrombosis and Haemostasis .

Dr Matthias Tacke

Hackenberg, F; Lally, G; Mller-Bunz, H; Paradisi, F; Quaglia, D; Streciwilk, W;

Tacke, M (2012) 'Synthesis and biological evaluation of N-heterocyclic carbene-

silver(I) acetate complexes derived from 4,5-ditolyl-imidazole'. Inorganica

Chimica Acta .

A. Deally, F. Hackenberg, G. Lally, M. Tacke (2012) 'Synthesis and biological

evaluation of achiral indole-substituted titanocene dichloride derivatives'.

International Journal of Medicinal Chemistry, Article ID 905981 .

F. Hackenberg, A. Deally, G. Lally, S. Malenke, H. Mller-Bunz, F. Paradisi, S.

Patil, D. Quaglia, M. Tacke; (2012) 'Novel non-symmetrically p-benzyl-

substituted (benz)imidazole N-heterocyclic carbene-silver(I) acetate complexes -

synthesis and biological evaluation'. International Journal of Inorganic

Chemistry, Article ID 121540 (13 pages).

C. M. Dowling, S. Cuffe, M. Tacke, A. Deally, M. Hogan, J. M. Fitzpatrick, R.

W. G. Watson; (2012) 'Manipulating the ability of novel titanocene analogues to

induce apoptosis in castrate-resistant prostate cancer cells'. Letters in Drug Design

& Discovery, 9 (3):226-233.

L. Kater, J. Claffey, M. Hogan, P. Jesse, B. Kater, S. Strauß, M. Tacke, A.

Prokop; (2012) 'The role of the intrinsic FAS pathway in Titanocene Y apoptosis:

The mechanism of overcoming multiple drug resistance in malignant leukemia

cells'. Toxicology in Vitro, 26 (1):119-124.

L. Kaps, B. Biersack, H. Mller-Bunz, K. Mahal, J. Mnzner, M. Tacke, T. Mueller,

R. Schobert; (2012) 'Gold(I)-NHC complexes of antitumoral diarylimidazoles:

structures, cellular uptake routes and anticancer activities'. Journal of Inorganic

Biochemistry, 106 (1):52-58.

R. A. Hilger, D. Alex, A. Deally, B. Gleeson, M. Tacke; (2011) 'Titanocene Y and

Vanadocene Y: Platinum Resistance-Breaking Cytotoxic and DNA-Targeting

Anticancer Drug Candidates'. Letters in Drug Design & Discovery, 8 (10):904-

910.

U. Olszewski, J. Claffey, M. Hogan, M. Tacke, R. Zeillinger, P. Bednarski, G.



http://dx.doi.org/10.1186/1471-2105-12-407

http://dx.doi.org/10.1074/mcp.M111.009241

http://dx.doi.org/10.1155/2012/905981

http://dx.doi.org/10.1155/2012/121540

http://www.benthamscience.com/contents-JCode-LDDD-Vol-00000009-Iss-00000003.htm

http://dx.doi.org/10.1016/j.tiv.2011.09.010

http://dx.doi.org/10.1016/j.jinorgbio.2011.08.026

Hamilton; (2011) 'Anticancer activity and mode of action of titanocene C'.

Investigational New Drugs, 29 :607-614.

S. Patil, A. Deally, F. Hackenberg, L. Kaps, H. Mller-Bunz, R. Schobert, M.

Tacke; (2011) 'Novel Benzyl- or 4-Cyanobenzyl-Substituted N-Heterocyclic

(Bromo)(carbene)silver(I) and (Carbene)(chloro)gold(I) Complexes: Synthesis

and Preliminary Cytotoxicity Studies'. Helvetica Chimica Acta, 94 :1551-1562.

Professor Cormac Taylor

Schaible B, Taylor CT and Schaffer K. (2012) 'Hypoxia increases antibiotic

resistance in Pseudomonas Aeruginosa through altering the composition of multi

drug efflux pumps'. Antimicrobial Agents and Chemotherapy .

Bruning U, Fitzpatrick SF, Frank T, Birtwistle M, Taylor CT, Cheong A (2012)

'NFkB and HIF display synergistic behaviour during hypoxic inflammation'.

Cellular and molecular life sciences : CMLS, 69 (8):1319-1329.

Oliver KM, Lenihan CR, Bruning U, Cheong A, Laffey JG, McLoughlin P, Taylor

CT, Cummins EP; (2012) 'Hypercapnia induces cleavage and nuclear localization

of REL B giving insight into co2 sensing and signalling'. Journal of Biological

Chemistry .

Cahill E, Costello CM, Rowan SC, Harkin S, Howell K, Leonard MO, Southwood

M, Cummins EP, Fitzpatrick SF, Taylor CT, Morrell NW, Martin F, McLoughlin

P; (2012) 'Gremlin plays a key role in the pathogenesis of pulmonary

hypertension'. Circulation, 125 (7):920-930.

Hams E, Saunders SP, Cummins EP, O'Connor A, Tambuwala MT, Gallagher

WM, Byrne A, Campos-Torres A, Moynagh PM, Jobin C, Taylor CT, Fallon PG;

(2011) 'The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic

shock via alternative activation of macrophages and IL-10 production by B1 cells'.

Shock, 36 (3):295-302.

Dr Emma C Teeling

Ruedi, M., Friedli-Weyeneth, N., Teeling, E.C., Puechmaille, S.J. and Goodman,

S.M. (2012) 'Biogeography of Old World emballonurine bats (Chiroptera:

Emballonuridae) inferred with mitochondrial and nuclear DNA'. Molecular

Phylogenetics and Evolution, 64 (1):204-211.

Boston, E.S.M, Puechmaille, S.J., Buckley, D.J., Lundy, M., Scott, D.D., Prodohl,

P., Montgomery, W.I. and Teeling, E.C. (2012) 'Empirical assessment of non-

invasive population genetics in bats: comparison of DNA quality from faecal and

tissue samples'. Acta Chiropterologica, 14 (1):45-52.

Puechmaille, S.J., Allegrini, B., Boston, E., Dubourg-Savage, M-J., Evin, A.,

Knochel, A., Le Bris, Y., Lecoq, V., Lemaire, M., Rist, D. and Teeling, E.C.

(2012) 'Genetic analyses reveal further cryptic lineages within the Myotis nattereri

species complex'. Mammalian Biology, 77 (3):224-228.

Thong, V.D., Puechmaille, S.J., Denzinger, A., Bates, P.J.J., Dietz, C., Csorba, G.,

Soisook, P., Teeling, E.C., Matsumura, S., Furey, N. and Schnitzler, H.U. (2012)

'Systematics of the Hipposideros turpis complex with a description of a new

subspecies from Vietnam'. Mammal Review, 42 (2):166-192.

Lundy, M.J., Buckley, D.J., Boston, E.S.M., Scott, D.D., Prodohl, P.A., Marnell,

F., Teeling, E.C. and Montgomery, W.I. (2012) 'Behavioural context of multi-

scale species distribution models assessed by radio-tracking'. Basic and Applied



http://dx.doi.org/10.1016/j.ympev.2012.03.019

http://dx.doi.org/10.3161/150811012X654259

http://dx.doi.org/10.1016/j.mambio.2011.11.004

http://dx.doi.org/10.1111/j.1365-2907.2011.00202.x

Ecology, 13 (2):188-195.

Thong, V.D., Puechmaille, S.J., Denzinger, A., Csorba, G., Dietz, C., Bates, P.J.J.,

Teeling, E.C. and Schnitzler, H.U. (2012) 'A new species of Hipposideros

(Chiroptera: Hipposideridae) from Vietnam'. Journal of Mammalogy, 93 (1):1-11.

Puechmaille, S.J., Ar Gouilh, M., Piyapan, P., Yokubol, M., Khin Mie Mie, Bates,

P.J.J., Satasook, C., Tin Nwe, Si Si Hla Bu, Mackie, I.J., Petit, E.J. and Teeling,

E.C. (2011) 'The evolution of sensory divergence in the context of limited gene

flow in the bumblebee bat'. Nature Communications, 2, Article No. 573 .

Puechmaille, S., Frick, W.F., Kunz, T.H., Racey, P.A., Voigt, C., Wibbelt, G. and

Teeling, E.C. (2011) 'White nose syndrome: is this emerging disease a threat to

European bats?'. Trends in Ecology and Evolution, 26 (11):570-576.

Meredith, R.W, Janecka, J.E., Gatesy, J., Ryder, O.A., Fisher, C.A., Teeling, E.C.,

Goodbla, A., Eizirik, E., Simao, T.L.L., Stadler, T., Rabosky, D.L., Honeycutt,

R.L., Flynn, J.J., Ingram, C.M., Steiner, C., Williams, T.L., Robinson, T.J., Burk-

Herrick, A., Westerman, M., Ayoub, N.A., Springer, M.S. and Murphy, W.J.

(2011) 'Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on

Mammal Diversification'. Science, 334 (6055):521-524.

Dr Douglas Veale

Moran EM, Connolly M, Gao W, McCormick J, Fearon U, Veale DJ; (2011)

'Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal

rearrangement'. Arthritis and Rheumatism, 63 (11):3263-3273.

de Hair MJ, Harty LC, Gerlag DM, Pitzalis C, Veale DJ, Tak PP; (2011) 'Synovial

tissue analysis for the discovery of diagnostic and prognostic biomarkers in

patients with early arthritis'. The Journal of rheumatology, 38 (9):2068-2072.

Adams R, Craig BM, Walsh CD, Veale DJ, Bresnihan B, FitzGerald O, Barry M;

(2011) 'The impact of a revised EQ-5D population scoring on preference-based

utility scores in an inflammatory arthritis cohort'. Value in health : the journal of

the International Society for Pharmacoeconomics and Outcomes Research, 14

(6):921-927.

Dr Xiangming Zhu

Guohong Xin, Xiangming Zhu (2012) 'A Facile and Highly Stereoselective

Synthesis of 1-Thiotrehalose'. Tetrahedron Letters, 53 :4309-4312.

I. A. I. Ali, X. Zhu, E. S. H. E1 Ashry, R. R. Schmidt (2012) 'Mode of alkylation

of alcohols with O-cyclopropylmethyl trichloroacetimidate and O-cyclobutyl

trichloroacetimidate'. Arkivoc, 2012 (vi):35-44.

Xiangming Zhu, Ravindra T. Dere, Junyan Jiang, Lei Zhang, Xiaoxia Wang

(2011) 'Synthesis of alpha-Glycosyl Thiols by Stereospecific Ring-Opening of

1,6-Anhydrosugars'. Journal of Organic Chemistry, 76 :10187-10197.

Dr Tadhg Ó’Cróinín

O Croinin T and Backert S. (2012) 'Host Epithelial Cell Invasion by

Campylobacter jejuni: trigger or zipper mechanism?'. Frontiers in Cellular and

Infection Microbiology, 2 (25).




http://dx.doi.org/10.1016/j.baae.2011.12.003

http://dx.doi.org/10.1644/11-MAMM-A-073.1

http://dx.doi.org/10.1038/ncomms1582

http://dx.doi.org/10.1016/j.tree.2011.06.013

http://dx.doi.org/10.1126/science.1211028

Back to Top

Other Journals

Dr Jarlath Nally

Emilie Chow, MD, Jaime Deville, MD, Jarlath Nally, PhD, Michael Lovett, MD, PhD

and Karin Nielsen-Saines, MD, MPH (2012) 'Prolonged Leptospira urinary shedding in

a 10-year old girl' Case Reports in Pediatrics .

Dr Peter O'Brien

Ramery E, OBrien PJ (2012) 'Evaluation of the cytotoxicity of organic dust components

on THP1 monocytes-derived macrophages using high content analysis' Environmental

Toxicology, DOI: 10.1002/tox.21759 .

Professor Ronan O'Connell

Rowan F, Docherty NG, Murphy M, Murphy TB, Coffey JC, O'Connell PR; (2011)

'Ileal pouch microbial diversity' Annals of Surgery, 254 (4):669-670.

Back to Top

Conference Publications

Dr Orina Belton

McCarthy C, Mooney D, de Gaetano M, James W, Fitzgerald DJ, Belton O (2012)

Activation of the Nuclear Receptor Coactivator PGC-1{alpha} Mediates an

Atheroprotective Effect Circulation Research,

McCarthy C, Duffy M, Mooney D, James W, Fitzgerald DJ, Griffin MD, Belton O,

(2012) Il-10 Regulates the Immunoregulatory Response in the Regression of

Atherosclerosis Circulation Research,


Ryan, S.M, Patel, H.B., Kornerup, K. N., Tajber, L., Umerska, A., Perretti, M., &

Brayden, D. J. ; (2011) Intra-articular delivery of salmon calcitonin nanocomplexes to

the K/BxN murine model of osteoarthritis 24th conference of the European Society of

Biomaterials,

Dr John Crean

Andrews D, Browne J, O'Donovan H, Faherty N, Oliver N, Wallace D, O'Brien C and

Crean J. (2012) Integrated signalling between CTGF and TGFβ2 leads to divergent

activation of canonical and non-canonical pathways controlling EMT in ARPE-19 cells:

Implications for the pathogenesis of proliferative vitreoretinopathy ARVO,

Faherty N, Curran SP, O'Donovan H, Martin F, Godson C, Brazil DP, and Crean J.

(2011) CCN2/CTGF increases expression of miR-302 microRNAs, which target the

TGFβ type II receptor with implications for nephropathic cell phenotypes American

Society of Nephrology,

Professor Mark Crowe

Lane, E.A., Crowe, M.A., Beltman, M., More, S.J. (2012) The influence of cow and

management factors on reproductive performance of Irish seasonal calving dairy cows

16th Annual ESDAR Conference, The European Society for Domestic Animal

Production, Dublin, Ireland,








Professor Oliver Fitzgerald

Stephenson A, Blake C, McKenna M, van der Kamp S, Cunningham C, Fitzgerald O,

McCarthy Persson U (2012) The effects of exercise and vibration training on balance in

postmenopausal women with osteopenia or osteoporosis- A randomised controlled pilot

trial RTRS 2012: Rehabilitation and Therapy Research Society 8th Annual Conference:

Promoting Health and Wellbeing: A Therapy Perspective,

Dr Tara McMorrow

Cassidy H, Slyne J, Johnston O, Brennan L, O'Riordan A, Conlon P, Ryan MP,

McMorrow T (2011) Metabolomic Profiling Of Chronic Allograft Nephropathy (CAN)

Resulting From Immunosuppressant Therapies In Post Renal Transplantation Patients

HUPO 10th World Congress, Geneva, Switzerland,

Dr John O'Connor

Wall AM, O'Connor JJ (2012) Tumour necrosis factor alpha does not impair long term

potentiation following an acute hypoxic insult FENS Barcelona,

Corcoran AE, Harney SC, O'Connor JJ (2012) Prolyl hydroxylase inhibition impairs

long-term potentiation in the rat hippocampus FENS Barcelona,

Mukandala GD, O'Connor, JJ (2012) TNF-α synthesis inhibition post hypoxia impairs

long-term potentiation in the dentate gyrus in vitro FENS Barcelona,

Fanning RA, McMorrow JP, Campion DP, Carey MF, O'Connor JJ (2012) Opioid

mediated activity in human term non-laboring myometrium Royal Academy of Medicine

in Ireland, Biomedical Sciences Section, Galway,

Fanning RA, Duffy N, Leonard M, Ahmed JJ, O'Connor JJ (2012) The oxytocic effect

of ergometrine on human myomterium in vitro does not involve 5-HT2 receptor

activation Royal Academy of Medicine in Ireland, Biomedical Sciences Section,

Fanning RA, Duffy N, Leonard M, Ahmed JJ, O'Connor JJ (2012) An investigation into

the effects of ergometrine on human myomterium in vitro International Society of

Obstetric Anaesthesia,

Wall AM, O'Connor JJ (2011) Acute hypoxia impairs the recovery of synaptic

transmission in the rat dentate gyrus and potentiates long-term potentiation in the

presence of tumour necrosis factor-alpha and picrotoxin Neuroscience Ireland Annual

meeting NUI Maynooth, Irish Journal of Medical Science,

Corcoran AE, O'Connor JJ (2011) Dimethyloxalyl Glycine Decreases Synaptic

Signalling and Impairs Long Term Potentiation in the Rat Hippocampus Neuroscience

Ireland Annual meeting NUI Maynooth, Irish Journal of Medical Science,

O'Connor JJ, Dalton M, Cavanni P, Large CH, Lowry JP (2011) A comparison of the

effects of the dopamine partial agonists aripiprazole and (-)- 3-PPP with quinpirole on

stimulated dopamine release in the rat striatum: studies using fast cyclic voltammetry in

vitro Neuroscience Ireland Annual meeting NUI Maynooth, Irish Journal of Medical

Science,

Corcoran AE, O'Connor JJ (2011) Acute effects of hypoxia and prolyl hydroxylase

inhibition on synaptic plasticity in the rat hippocampus Soc Neuroscience,

Dr Kevin O'Connor

Guzik M, Duane G, Kenny S, Casey E, O'Connor K (2011) Mathematical modelling of

the bioprocess for PHA production European Congress of Applied Biotechnology,





Berlin,

Dr Albert Smolenski

Hampson, A; Neumüller, O; Gegenbauer, K; Smolenski, A (2011) Synaptotagmin-like

protein 4 regulates platelet granule secretion 13th UK Platelet Group Meeting, Cardiff,

Gegenbauer, K; Blanco-Fernandez, A; Elia, G; Smolenski, A (2011) Cyclic nucleotide

dependent protein kinases inhibit platelets by removing 14-3-3 from GTPase-activating

proteins 13th UK Platelet Group Meeting, Cardiff,

Dr Tadhg Ó’Cróinín

Scanlan E, Shortt C, Bourke B, and O Croinin T (2012) DNA Supercoiling in

Campylobacter jejuni: A Potential Trigger for Invasion American Society of

Microbiology, General Meeting,

Shortt C, Scanlan E, Bourke, B and O Croinin T (2012) Alteration of DNA Topology

leads to changes in Flagella gene expression in Campylobacter jejuni American Society

of Microbiology, General Meeting,

Shortt C, Scanlan E, Bourke B and O Croinin T (2012) DNA topology influences

motility and chemotaxis in the enteric pathogen, Campylobacter jejuni SGM General

Meeting,

Scanlan E, Shortt C, Bourke B and O Croinin T (2012) A link between DNA topology

and the invasive phenotype of Campylobacter jejuni SGM General Meeting,

Back to Top

Other Publications

Professor Mohamed Al-Rubeai

Al-Rubeai M.; (2011) Workshop on Developing Skills in Research Methodology.

Raparin University: Abstract.

Al-Rubeai M.; (2011) Workshop on Cell Culture and Production of

Biopharmaceuticals. Koya University: Workshops.

Al-Rubeai M.; (2011) Workshop on Developing Skills in Research Methodology.

Salahaddin University: Workshops.

Al-Rubeai M.; (2011) Working group on quality assurance & accreditation. Ministry of

Higher Education, Baghdad, Iraq: Policy Contribution.

Al-Rubeai M. ; (2011) Workshop on Developing Skills in Research Methodology.

University of Baghdad: Workshops.

Al-Rubeai M.; (2011) Working group on quality assurance & accreditation. Ministry of

Higher Education, KRG, Iraq: Policy Contribution.

Al-Rubeai M.; (2011) Scientific Research in Iraq: Situation and Perspectives, Meeting

of Core Group of Experts, UNESCO. Workshops.

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report of president 2011/2012 - conway institute · 2020. 7. 17. · report of president 2011/2012...

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