REVIEW OF DRUG THERAPIES USED

TO MANAGE COVID 19 PATIENTS

IN KENYA

Dr. Ann Mercy Wanjiru – Pharmacy, KUTRRH

Dr. Rosaline Kinuthia – Pharmacy, KNH

Dr. Eric Guantai - UON- School of Pharmacy

Dr. Christabel Khaemba - Pharmacy and Poisons Board

Outline

Medicine Use Evaluation at KUTRRH – Dr. Wanjiru

Medicine Use Evaluation at KNH – Dr. Kinuthia

Critical Review of Literature – Dr. Guantai

Pharmacovigilance – Dr. Khaemba

MEDICINE USE EVALUATION:

MANAGEMENT OF COVID 19

PATIENTS AT KNH

Dr. Rosaline Kinuthia

Clinical Pharmacist

KNH

Methodology

Review of treatment sheets and medical records of

patients tested positive for COVID 19 and admitted

at the KNH Isolation units (IDU, Mbagathi, Daycare)

Information collected:

IP number

Age

Any co-morbidities

Signs and symptoms presented

Medicines used during the hospital stay

Results: Age Distribution

1

11

283

43

0 10 20 30 40 50

< 15

30 - 59

Total

ComorbiditiesCo-morbidity No. of

patients

Symptoms

Asthmatic 2 Sore throat, cough

Diabetes, hypertension 1 asymptomatic

Diabetes 1 Sore throat,

headache, running nose

DM/ HTN/Asthmatic 1 ,,

COPD, active smoker 1 Fever, sore throat

HIV 1 Fever, sore throat

Running nose

HIV/DM/HTN 1 ,, , muscle pain

Arthritis 1 Headache, dizziness

PUD 1 ,, DIB, malaise

TOTAL 10

Symptoms

Frequently Prescribed Medication

Additional Medication

Amitryptylline

Montelukast

Bisacodyl

Clarithromycin

Meloxicam

Mouth wash

Chlorpheniramine

Pregabalin

Antihypertensive

Antidiabetics

HAART

Rizatriptan

Concerns on rational drug use-1

Management of the 9 asymptomatic patients

Treatment Number

Vitamin C 2

Vitamin C + Zinc 2

Vitamin C+ Zinc + Clarithromycin 1

Vitamin C + Paracetamol 1

Multivitamin + Bromazepam 1

Multivitamin + Desloratidine 1

No medication 1

Total 9

Concerns on rational drug use-2

Antimicrobial choice and switches

Multiple antibiotics prescribed

Completion of doses

Indications (or lack thereof) of prescribed

medication

Pharmacy support in COVID 19 Pandemic

Availability of prescribed medication

Medicine reconciliation, for co-morbids

Rationalizing need for various medications

Drug-drug interactions and ADRs monitoring

Suggesting therapeutic switches/ substitutions to the

Prescribers

Pharmacy support in COVID 19 Pandemic -2

Continuity of care

Home Medicine Delivery services where feasible Early refills

Supply of larger quantities

Supply without ‘valid’ prescription

Risk mitigation e.g. for medicines at risk of shortages

Compounding hand sanitizers

Continuing education on clinical and regulatory

changes

Acknowledgement

Data collection and correlation:

• Dr. Salima Chemjor – Pharmacist ,Mbagathi IDU, KNH

• Ms. Mary Munzyu – Incharge A&E Pharmacy, KNH

• KNH Health Information Department

Data analysis and report preparation:

• Dr. Dorothy Aywak – KNH

• Dr. Irene Weru - KNH

• Dr. Nicholas Mwaura - NQCL