sigma-aldrich 2013 global citizenship report

What if Science Changed the World?

2 0 1 3 G L O B A L C I T I Z E N S H I P R E P O R T

Letter from President and CEO Rakesh Sachdev 4

Letter from Steve Walton, VP of EH&S, Compliance and Sustainability 5

2013 GC Progress Report 6

Company Profile 7

Company Overview 8

Materiality Matrix 10

Environmental Sustainability 11

GC1015 Goal #1: Waste Intensity 12

GC1015 Goal #2: Emissions Intensity 15

GC1015 Goal #3: Water Efficiency 18

GC1015 Goal #4: Energy Efficiency 20

GC1015 Goal #5: Supply Chain 23

GC1015 Goal #6: Greener Alternative Products 28

Social Responsibility 36

GC1015 Goal #7: Team Sigma-Aldrich 37

Employees Giving Back 38

STEM Update 40

Corporate Giving 46

Our People 48

Diversity Commitment 51

Employee Development 52

HR 2013 Focus 53

Our Customers 54

Compliance 56

Safety 57

Fiscal Accountability and Governance 58

3rd Party GRI In Accordance Core Verification Statement 64

GRI Index 65

United Nations Global Compact Index 75

TABLE OF CONTENTS

W HAT IF SCIENCE CHANGED T HE WORLD?4

Each year I appreciate having this opportunity to share with you how our 9,000-plus employees are working to make the world a cleaner, healthier, safer place to live. And every year I’m proud to report on how our employees are helping us live our mission of enabling science to improve the quality of life. We have a range of programs in place to help us achieve this mission from the delivery of products that use fewer natural resources, to the engineering of more efficient packaging solutions that reduce waste, to engaging our communities in sharing the importance of science education. 2013 was an exciting year for Sigma-Aldrich. We recorded our 39th year of consecutive growth in earnings per share. We realigned our Company into three market-facing business units: Research, Applied and SAFC Commercial focused on the unique needs of research laboratory customers; diagnostic and testing and industrial customers; and pharmaceutical and electronics manufacturers respectively. This transition helped contribute to a 7% increase in net income and a 19% increase in free cash flow with 4% organic sales growth. Along with our financial success, our Global Citizenship efforts yielded very positive results. We made significant headway on our Global Citizenship Initiative –

GC1015. We once again outperformed our expectations with respect to water use, posting an absolute reduction of 111,000 cubic meters of water. This represents a total reduction of more than 650,000 cubic meters of annual water usage since 2009. Our energy initiatives showed positive signs despite weather driven spikes in natural gas use that drove our total energy usage above our goal for 2013. I am also very pleased with the excellent improvements we made in electricity usage, which has been a key focus since we launched our 10 Facilities project. The absolute reduction of electricity by four million kilowatt hours was a significant accomplishment and it makes me confident we are headed in the right direction in mitigating our carbon footprint. One of the biggest impacts we have on the environment is to help our customers reduce the environmental impact of their own research and development activities through the use of greener alternative products. These products are gaining in popularity so much so that we recently launched a greener alternatives identifier on our website making it easier for researchers to make greener purchasing decisions. We have 10 Centers of Green Chemistry Excellence around the world, enabling us to increase our focus on building a talent bench and mindset of resource efficiency and waste reduction. Our team is seeing success in the development of innovative, environmentally-friendly solutions to some of the most common problems facing researchers today. We enhanced our commitment to the community through increased philanthropic contributions in our three focus areas for giving: STEM (Science, Technology, Engineering and Mathematics) Education, Scientific Research and Economic Development through Science. Our employees have joined this effort by sharing their skill and experience in classrooms around the world, bringing practical science applications to thousands

FROM OUR PRESIDENT & CEO

of students through our recently launched Sigma-Aldrich Science Partners Program. These efforts are yielding results not just in the classroom. Our employees are reporting stronger engagement at work after participating in these sessions. In 2013, we were once again recognized by some of the leading environmental and social responsibility indexes in the world. We added recognition from the Dow Jones Sustainability Index to our list of accomplishments and were named for a second time to CDP’s Carbon Disclosure Leadership Index. We were also recognized by the Civic 50 for the second year in a row and received the top ranking in the Materials sector for our strong community engagement efforts. Additionally, we were recognized by inclusion on both the NSYE Euronext Vigeo 120 and the MSCI World SRI Index. All of this recognition is a testament to the great work our employees are doing. We believe that the successes we are achieving in our sustainability program serve as a key benchmark not only for our sector, but also for the business world at large – and this incentivizes us to take our efforts to new levels as we work to solve some of the world’s biggest challenges.

Global Citizenship at Sigma-Aldrich is a differentiator. In an increasingly complex business environment, we are able to set ourselves apart by partnering with our customers not only on science, but on delivering science in a more sustainable fashion. We have the unique opportunity to positively affect our environment by helping scientists tackle their problems with creative solutions. We know from the work we do every day that together Sigma-Aldrich and science have the potential to change the world.

RAKESH SACHDEV

President and Chief Executive OfficerG4-1

2013 SIGMA-ALDRICH GLOBAL CI T IZENSHIP REPOR T 5

FROM OUR VICE PRESIDENT OFEH&S, COMPLIANCE AND SUSTAINABILITY

In our 2012 Sustainability report I mentioned that while I was proud of the recognitions and rewards our Global Citizenship effort had garnered for the Company, I was even more proud of the effort and action that positioned us to achieve greater success in the coming years. As I look back at 2013, I’m happy to report I was right. Rakesh covered many of the highlights from 2013, our best yet from both a Company and Global Citizenship perspective, so I won’t go over those again in detail. However, I would like to discuss a few particular achievements. The execution of our Global Citizenship Initiative (GC1015) has resulted in not just real-time achievements but also a deeper understanding of the targets we need to set for long-term success. In 2013, the Global Citizenship team partnered with the Supply Chain organization on a number of engineering and procurement projects that resulted in dramatic reductions in water and electricity usage in many of our facilities. The details of this excellent result are available in this year’s report. While Sigma-Aldrich has a long history of green chemistry initiatives, projects and products, 2013 saw a true crystallization of a Green Chemistry effort that is focused on internal process “greening” as well as the development of enhanced customer-facing green solutions and products. By integrating sustainability into our processes, products and solutions, we have created a new way to increase our positive impact on the environment and to engage both Sigma-Aldrich employees and customers in “Greening the Supply Chain.”

On the community front, I am proud of the many efforts launched, sustained, or improved upon in 2013. One such effort was the launch of our Science Partners Program. As a leading life science and technology company, Sigma-Aldrich has access to one of the world’s largest and most talented resource pools – our own scientists. The Science Partners Program gives schools in proximity to Sigma-Aldrich facilities around the world the opportunity to work directly with our employees to bring real world experiments into the classroom. The goal is to inspire students, to engage our employees in community outreach, and to expand our ability to give back in the communities where we do business. Our plan is to expand this effort over the next three years across the U.S. and beyond so that we reach roughly 30,000 children annually. The Global Citizenship Initiative of the past four years has accomplished many great things for our employees, our customers and our communities. But despite the numerous achievements, awards and recognitions we’ve received, the most exciting part is that we are just getting started. We have more goals yet to achieve (or exceed!), more ideas to explore, and more challenges we can’t wait to address. We hope you are as excited about the future as we are.

STEVE WALTON

VP of EH&S, Compliance and Sustainability


2013 PROGRESS REPORT

Sigma-Aldrich recorded its strongest overall Global Citizenship performance in the fourth year of the current Global Citizenship Initiative (GC1015). Here’s a quick snapshot of some of the projects that drove our performance in 2013.

Waste

Emissions

Water

Energy

Supply Chain

Greener Alternative Products

Team Sigma-Aldrich

GC1015 GOAL PROGRESS COMPLETED IN 2013

80% Complete

60% Complete

100% Complete

50% Complete

50% Complete

56% Complete

46% Complete

• Enhanced transparency on waste origination• Diversion of more waste to Beneficial Reuse Channels• Implementation of waste to recycling diversion projects

• Implementation of new systems to reduce emissions to air of other GHG’s

• Implementation of Scope 3 reduction projects and targeted goals

• Elimination of final single pass cooler at a major production facility

• New manufacturing processes to reduce water required for production

• Initiation of 10 Facilities project, yielding an absolute electricity use reduction

• Installation of second solar array

• Engagement with suppliers regarding the Supplier Code of Conduct

• Planned launch of onsite ESG vendor auditing in 2015

• Launch of Greener Alternatives search icon on sigmaaldrich.com• Introduction of more than 20 reengineered products with

smaller environmental footprints

• Site engagement with leadership and employee groups• Increased volunteer opportunities around the world

G4-2


COMPANY PROFILE

PRODUCTSLeading the way in the

life science and high technology materials

markets.

230,000 Reagents and Chemicals

40,000 Laboratory Equipment Items

GEOGRAPHIESEnhancing our global reach through service excellence.

(Percent of 2013 total sales)

43% Americas 38% Europe/Middle East/Africa

19% Asia Pacific

CUSTOMERSMore than 1.4 million individual customers

worldwide in more than 100,000 accounts.

52% Research 23% Applied 25% SAFC Commercial

CORPORATE SAFETY PERFORMANCE

RECORDABLE INJURY RATE (RIR)Number of injuries


SERIOUS INJURY RATE (SIR)Serious injury = three or more days lost work

$100Minvested in Capital projects around the

world in 2013

$66Minvested in Research and Development

around the world in 2013

$1,955Minvested in raw materials, other costs of goods sold and SG&A expenses in 2013

$137Minvested in payroll, pension

and benefits in 2013

$336M in total debt obligations

$5.726B in equity

2013 AWARDS & RECOGNITION• CDP

- Carbon Disclosure Leadership Index

• DJSI- First year recognized on the list

• Civic 50- #1 in the Materials sector

• NYSE Euronext Vigeo 120

• MSCI World SRI Index

SALES$ Millions

QUALITY SYSTEM IMPLEMENTATION

Number of facilities with certification

Sigma-Aldrich RIR Industry Average

EC1, G4-9


COMPANY OVERVIEW

Organizational Profile Sigma-Aldrich Corporation was incorporated under the laws of the state of Delaware in May 1975 and was the result of a merger between Aldrich Chemical Company and Sigma Chemical Company. The Company’s principal executive offices are located at 3050 Spruce Street, St. Louis, Missouri, 63103. The Company’s primary brands are Sigma®, Aldrich®, Fluka®, Supelco® and SAFC®. The Company introduced in 2013, a customer-centric organizational structure composed of three business units: Research, Applied and SAFC Commercial. The Company sells to researchers in more than 160 countries, servicing more than 100,000 accounts representing more than 1.4 million customers. Sigma-Aldrich operates directly in 37 countries and, through a comprehensive dealer network, in over 100 other countries around the world. We manufacture roughly 70,000 of the 230,000 chemical and biologic products we offer and we distribute over 40,000 laboratory equipment items. During the 2013 calendar year, Sigma-Aldrich had chemical production facilities and distribution centers in Madison, Milwaukee, Sheboygan, and Verona, Wisconsin; St. Louis, Missouri; Lenexa, Kansas; Houston and Round Rock, Texas; Allentown and Bellefonte, Pennsylvania; Rockville, Maryland; Haverhill and Natick, Massachusetts; Urbana, Illinois; Cleveland and Miamisburg, Ohio; Carlsbad, California; Laramie, Wyoming; Australia; Brazil; Canada; China; France; Germany; India; Ireland; Israel; Japan; Singapore; South Korea; Switzerland; Taiwan; and the United Kingdom. There were also no significant acquisitions or divestitures in 2013.

Germany

Hungary

India

Ireland

Israel

Italy

Japan

Luxembourg

Malaysia

Mexico

Argentina

Australia

Austria

Brazil

Canada

Chile

China

Czech Republic

Denmark

France

Netherlands

New Zealand

Poland

Portugal

Russia

Singapore

Slovak Republic

South Africa

South Korea

Spain

Sweden

Switzerland

Taiwan

Thailand

United Kingdom

United States

Vietnam

SIGMA-ALDRICH WORLDWIDE

Sales Distribution Production

G4-3, G4-4, G4-5, G4-6, G4-7, G4-8, G4-9, G4-13, G4-17, G4-18, G4-22, G4-23, G4-24, G4-25, G4-26, G4-27, G4-28, G4-29, G4-30, G4-31, G4-37, G4-46


Reporting Criteria and ApproachOur Global Citizenship reporting period is based on a calendar year and the reporting cycle is annual, with the most previous report released in 2012. This Report has been created by the Global Citizenship department working with both internal and external stakeholders. The content of this Report is generally limited to information that is relevant and material to the overall support of Sigma-Aldrich’s Global Citizenship Initiative (GC1015), which was established in 2009. We prioritize information concerning discrete projects according to the ability of each project to help Sigma-Aldrich achieve the goals set out in the GC1015. The scope of this Report includes Sigma-Aldrich Corporation and all of its affiliates worldwide. Sigma-Aldrich has created this Report for its stakeholders, including customers, shareholders and employees. The level of engagement of our various stakeholders is based on the impact that information provided in this Report would have on the relevant stakeholder group. The Company uses feedback from stakeholders through survey based queries and data requests from our customers, analysts, shareholders and organizations such as ACS, SOCMA, NAM, Community and Non-Profit Organizations as its guidance on stakeholder inclusiveness and bases the Sustainability Context on relevant competitors in industry. We are pleased to note Sigma-Aldrich has received no community feedback regarding actions that need to be taken to address any of our Global Citizenship priorities. We engage with our stakeholders throughout the year on progress against our goals, not just as part of the reporting preparation process. The Company utilizes best practices in measurement and reporting, including standards from the GHG Protocol. For all waste generation, water and energy use and emissions generation, information from utility bills is utilized to calculate progress against goals For emissions of substances like HAP’s, PM’s, etc., EPA guidelines are

Sigma-Aldrich works collaboratively with its partners around the world to improve the environment, support local communities and increase understanding of the business sector. All customers and their organizations are considered by the Company to be stakeholders. Due to the nature of our business and the number of customers we have, we must limit active engagement to those of our larger customers for which information regarding our environmental and social policies and programs is critical to their own sustainability programs.

We work with our Global Advisors Panel, a cross section of 5,000 customers from around the world, to identify, measure and report relevant concerns and interests. Additionally, we work collaboratively with stakeholders in the communities around the world at which we have a presence to understand the needs of our local communities and address them as best we are able.

used in our calculations. All significant assumptions regarding measurement of results and calculations are listed in the applicable data tables found in this Report. Data presented in the Report is updated annually, while some narrative content may be repeated from year to year. The General Counsel of the Company formally reviews and approves the organization’s sustainability report and ensures that all material aspects are covered as outlined by GRI requirements. The Report is distributed to and reviewed with the Company’s Board of Directors. All questions regarding this Report or its contents should be directed to Jeffrey Whitford, Manager, Global Citizenship at [email protected].

This report also serves as Sigma-Aldrich’s Communication on Progress for the United Nations Global Compact (UNGC), of which Sigma-Aldrich is a signatory. An index to the UNGC indicators in this report can be found on page 75. More information about the UNGC can be found at www.unglobalcompact.org.

RestatementsWe are restating the prior years’ reports regarding Waste Intensity and Scope 3 Business Travel Emissions. Because we have been unable to retrieve complete historical waste data for two acquisitions made in 2012, we are unable to re-baseline our waste numbers for the time period of 2010 to 2011. As a result, we have removed those two acquisitions from the goal set data and therefore will show a 13% intensity reduction improvement for 2012 rather than a 6% improvement, we will however report waste totals including acquisitions in our total waste generation numbers. Due to new Defra guidelines on uplift factors, we have revised our 2012 Scope 3 Business Travel Emissions. That number is now 5,059 metric tonnes of CO

2.

G4-48, G4-DMA


MATERIALITY MATRIXST

AK

EHO

LDER

IMPA

CT

SIGMA-ALDRICH IMPACT

L

H

H

G4-19, G4-20, G4-21

Sigma-Aldrich Sigma-Aldrich and customers Customers

Sigma-Aldrich has continued to refine its approach to materiality in Global Citizenship reporting over the past two years. The balance between materiality and transparency continues to be a difficult balance due to the proliferation of reporting frameworks. We have chosen to continue to build on the relevant Global Citizenship data set, answering as many of the questions that we receive from various stakeholders and compiling them into one location while trying to minimize content that does not support our Global Citizenship mission.

Ethical Business Practices

Product QualityProduct Breadth/Availability

Energy Use in Manufacturing

Managing Waste

Responsible Product Management

Water Reintroduction

Supply Chain TransparencyWomen in Science

Energy Efficiency

Biodiversity Workforce Development

Supplier Code of Conduct

Fiscal Accountability

STEM Education Regulatory Compliance

Hazardous Waste Handling

Community Involvement/Philanthropy

Employee Engagement

Sustainable Facility Design

Water Use in Production

Innovation in Products

Beneficial Reuse

Product Safety

Shipping

Supplier DiversityAlternative Energy

Green Chemistry

We have evolved how we view materiality by distinguishing priorities by stakeholder group and those that we see as shared priorities. This approach has given us clearer guidance not just on what our stakeholders deem relevant, but also the identification of ways that we can engage our stakeholders on topics that might be outside of their realm of consideration. The Materiality Matrix was constructed using feedback from stakeholders, such as our Global Advisors Panel and internal stakeholders. Impact assessment was made based on the priority that stakeholders gave to a topic through surveying. The results were then plotted and assigned to one of three categories based on the stakeholder group.


What if science could solve climate change? As a leading Life Science and Technology company, we know the power of science and what it can do. We know that some of the biggest challenges facing the world today will be solved by the scientists who are our customers, as well as our own scientists, who are working on breakthrough projects. Our accomplishments in 2013 built upon the success of 2012. We see momentum growing behind the idea of individual Global Citizenship at Sigma-Aldrich as our employees are exposed to more information about sustainability, what the Company is doing and how they can play a role in our collective success. Our employees are starting to connect the dots on how their actions enable us to achieve our goals. This increase in engagement has been driven by strong organizational leadership that has integrated Global Citizenship into much of what we do. In the Environmental Sustainability section of this Report, we provide an update on the progress we’ve made on our Global Citizenship Initiative (GC1015) Goals and describe the key projects that have helped us achieve that progress As we transition to G4 reporting this year, we will sharpen our focus on the G4 standards we consider to be most material to our operations and impact on the environment, linking those items directly into our reporting.

ENVIRONMENTAL SUSTAINABILITY

UPDATES

4MkWh absolute reduction in electricity usage

1.9Mm3 of water saved since 2009

6%Increase in Beneficial Reuse


GC1015 GOAL #1WASTE INTENSITY

One year after having established the baseline for Goal #1 we’ve made significant progress. We also have identified additional challenges and opportunities regarding waste generation at Sigma-Aldrich. We updated our baseline and progress numbers to exclude two of the acquisitions we made in 2012, BioReliance and Research Organics, due to the fact that neither company had reliable waste data going back to 2010, the starting point of our GC2015 Initiative. We still will be reporting totals for all sites, including those of BioReliance and Reseach Organics, but our progress against our goal has been adjusted to exclude the locations at which these two companies conduct business.

SCOPE 3 EMISSIONS FROM WASTE

23,998metric tonnes of CO

2

Goal

20% Intensity Improvement by 2015

Waste Numbers

USAGE SALESDOLLARS/

TONNE OF WASTEINTENSITY

IMPROVEMENT2010 11,885 $2,271,000,000 $191,081.19 Baseline2011 12,676 $2,505,000,000 $197,617.54 3%2012 12,196 $2,623,000,000 $215,070.51 13%2013 12,227 $2,704,000,000 $221,149.91 16%20142015 $229,297.43 20% Goal

Beneficial Reuse of SolventsSIGMA-ALDRICH BENEFICIAL REUSE PROGRAMReported in tonnes

Progress

80%16%Intensity Improvement through 2013


WASTE AND RECYCLING NORMALIZED TO SALES

Sales dollars for every 1 tonne of waste or recycling

Landfill: $597,437 Non-Hazardous waste: $518,007 Hazardous waste: $750,902 General recycling: $1,163,511 Beneficial Reuse: $271,077

WASTE BY REGION

Reported in tonnes

Americas: 4,893 EMEA: 8,308 APAC: 146

LOCAL PROGRESS – ST. LOUISReported in tonnes

WASTE

12% improvement

HAZARDOUS WASTE

65% improvement

WASTE TOTALS

2013 WASTE TOTALSIn tonnes

WASTE

13,347

Landfill: 4,526 Non-Hazardous waste: 5,220 Hazardous waste: 3,601

RECYCLING

12,298

General recycling: 2,324 Beneficial reuse: 9,974

Sigma-Aldrich is not able to use recycled materials in its products due to the specifications of our customers. Typical specifications require products with greater than 98% purity. It is currently not possible to produce products, especially in a regulated environment, that typically employs cGMP practices.

Waste StreamsIn 2013, 100% of our facilities have measured and reported landfill, hazardous and non-hazardous waste and recycling and beneficial reuse waste generation numbers. Sigma-Aldrich has a long history of proactive, positive management of hazardous waste. It is, in fact, a core strength of the Company. All of our sites have management practices in place designed to minimize, to the extent possible, the amount of hazardous materials used in our processes. We have equally strong systems in place to manage hazardous materials created as waste in the conduct of our operations. For more than 30 years, Sigma-Aldrich has gone well beyond regulatory requirements by thermally destroying (incinerating) chemical waste instead of sending this waste to landfills. We see the additional cost of incineration as a sound investment in the future of our planet.

We have identified five categories of waste streams as outlined below.

1. General Landfill

2. Hazardous Waste (examples include Methyllithium in

Diethyl Ether, Phosphorus Trichloride and Methanesulfonyl Chloride)

3. Non-Hazardous Waste

4. Recycling

5. Beneficial Reuse

EN23


Milwaukee, WisconsinSigma-Aldrich has a history of Process Improvement (PI) that has enabled us to accelerate our sustainability progress throughout the Company. A good example of how we use PI in our sustainability efforts comes from our affiliate in Milwaukee, Wisconsin. In late 2012, Sheri Williams, Facilities Team Leader, had an idea of how she could use process improvement to address an environmental issue she had identified - an increase in the amount of shrink wrap that was being thrown away.

Sherri started her Process Improvement by identifying the opportunity. In 2012, our Teutonia facility in Milwaukee had become Sigma-Aldrich’s main CDC, handling an increased volume of shipments from all around the world. With this increased volume came increased recycling volumes, almost 4x the amount of cardboard, but also increased waste from other materials. Sheri created a project to help reduce the amount of waste generated at the Teutonia site by focusing on shrink wrap. She partnered with a local waste provider to investigate possible means to recycle shrink wrap since we couldn’t recycle it in our traditional in-house channels. After several tests conducted with our distribution teams, Sheri is on her way to recycling more than 20 tons of shrink wrap annually. This is just one example of how our employees are taking an active ownership of Global Citizenship at the individual level.


GC1015 GOAL #2EMISSIONS INTENSITY

Our 2013 carbon footprint emissions numbers improved slightly over 2012. Performance was affected by two extreme weather months that significantly increased natural gas usage, which pushed up our CO

2 footprint, specifically our Scope 1 footprint, in comparison with

2012. We did see improvement in our Scope 2 footprint, which historically had been the fastest growing of the two scopes. We now have accomplished 60% goal completion and expect that investments made in energy reduction the last two years will help us meet and exceed our Emissions Intensity goal. In 2013 we increased our focus on Scope 3 emissions by expanding reporting through the addition of another category as well as improvements to the air to ocean project started in 2012, both of which have lead to a significant reduction in our Scope 3 upstream distribution emissions.

2013 EMISSIONSSCOPE 1 DIRECT EMISSIONS*

61,877NORMALIZED VALUE

.00002tonnes/sales dollar

SCOPE 2 INDIRECT EMISSIONS+


.00006 tonnes/sales dollar

TOTAL SCOPE 1 & 2 EMISSIONS


.00008tonnes/sales dollar

*Scope 1 emissions are comprised of Natural Gas, Fuel Oil, Kerosene, Diesel, Gasoline, LPG

+Scope 2 emissions are comprised of Electricity, Delivered Heat and Steam

Goal

20% Intensity Improvement by 2015

Emissions Numbers

USAGE SALESDOLLARS/

TONNE OF CO2

INTENSITY IMPROVEMENT

2010 210,244 $2,271,000,000 $10,801.74 Baseline2011 218,464 $2,505,000,000 $11,466.42 6%2012 221,469 $2,623,000,000 $11,843.64 10%2013 224,272 $2,704,000,000 $12,056.79 12%20142015 $12,962.08 20% Goal

Progress


EN15, EN16, EN18


SCOPE 3 EMISSIONS

In 2011, Sigma-Aldrich made a commitment to increase its reporting on Scope 3 emissions. In 2013, we added the Scope 3 category Waste Generated in Operations with the goal of adding, at a minimum, one additional Scope 3 category each year.

GOAL

5%absolute reduction of Scope 3 emissions

for Upstream Transportation

RESULT

29%absolute reduction of Scope 3 emissions for Upstream Transportation due to the

Air to Ocean project and smarter logistics regarding bulk material movements.

For more on our Air to Ocean Scope 3 Upstream Transportation Reductions please see page 25 in the Supply Chain section.

EN17, EN21

China 1,858.045Germany 6,168.209India 2,956.097Israel 9,813.026Switzerland 1,254.655Taiwan 1,873.113United Kingdom 13,483.618United States 179,037.843

Global EmissionsReported in tonnes

% CHANGEPurchased goods and services

NCR NCR

Capital goods NCR NCRFuel and energy NCR NCRUpstream transportation and distribution

43,4591 29%

Waste generated in operations

23,9982 NCR

Business travel 7,4103 44%Employee commuting

NCR NCR

Upstream leased assets

0 0

Downstream transportation and distribution

NCR NCR

Processing of sold products

NCR NCR

Use of sold products

NCR NCR

End-of-life treatment of sold products

NCR NCR

Downstream leased assets

0 0

Franchises 0 0Investments 0 0TOTAL 74,867

1. This number represents at least 75% of emissions from shipping activities.

2. First year reporting Scope 3 Waste generated in operations.

3. This number represents US and EMEA travel, providing greater than 85% of our estimated travel related emissions.

NCR = not currently reported


CDPSigma-Aldrich has reported to the CDP (formerly known as the Carbon Disclosure Project) for the past six years. Each year we have made gains on our disclosure score by increasing the breadth and depth of our reporting. In 2013, we continued to improve not only the scope of our disclosure but also performance. Our disclosure score increased from 95 to 97 and our performance band increased from C to B. Through participation in CDP, Sigma-Aldrich has strengthened its policy on Climate Change and we remain committed to improving our carbon footprint as our Company continues to grow.

CDP PERFORMANCE

OTHER EMISSIONS

Sigma-Aldrich continues to challenge its operational sites to better manage and reduce emissions. Several of our sites hold operating permits and must report their air emissions to regulatory bodies, while other smaller sites are not required to report their emission numbers, and for these locations, emissions are estimated. In late 2012, our Bellefonte, Pennsylvania site took a major step to reduce its emissions by removing a large waste tank. The waste tank system had previously required the use of an in-line charcoal filter which required changing every 45 days. Site Management worked with the Pennsylvania Department of Environmental Protection to identify alternatives to the tank filters eventually concluding that the use of plastic totes for waste shipments would eliminate the need for charcoal filters and the resulting carbon waste generated thereby. The site also changed out two parts washers that used VOC’s in favor of a more environmentally friendly aqueous cleaning solution. These changes increased operational efficiency and, because of the reduction of air emissions at the site, eliminated the need for an air permit.

In tonnes

2013 2012 2011NOX 35.32 34.45 40.04 SOX .15 0.26 0.29VOC’S 41.26 72.58 66.87PM 1.39 3.68 3.11CO 30.21 28.83 27.42HAP’S 22.34 61.03 43.93DIOXIN’S 0 0.02 0.02METHANE .115 NR NR

In 2013, Sigma-Aldrich had no air emissions of metals beyond trace quantities and therefore was not subject to regulatory reporting requirements related to metal emissions.

Sigma-Aldrich does not utilize carbon offsets and did not purchase or sell carbon credits in 2013. Sigma-Aldrich did not use any carbon sequestration or capture technologies in 2013.

TRI EMISSIONS

2,297.97 tonnes

APAC EMEA Americas TOTAL Normalized to sales*NOX .01 1.8524 33.4602249841241 35.3226249841241 0.00000001306213SOX .0082 0.0405 0.111 0.1597 0.000000000058060VOC’S 1.523 842.72 34.0231339018416 41.26 0.00000001523888PM . 0356 0.0558 1.3 1.3936 0.00000000051538CO 0 0.2967 29.9157380023587 30.2124380023587 0.000000011173239HAP’S 0 0 22.34 22.34 0.000000008261834DIOXIN’S 0 0.0000000307 0 0.0000000307 0METHANE 0 0 0.115 0.115 0.00000000004253

*tonnes/sales dollar

Emissions represent at least 75% of emissions from Sigma-Aldrich’s global operations.

Score Grade


GC1015 GOAL #3WATER EFFICIENCY

Over the past year water has become a topic of interest globally, and especially for corporations, as regions struggle with increasing instances of extreme drought. In 2010, Sigma-Aldrich initially committed to a 10% intensity reduction in water usage. In 2011, we announced a new 30% intensity reduction target given the immediate success of actions we instituted under this program. In 2012, we continued our strong water reduction activities and recorded a second straight year of absolute reduction, while continuing to grow sales. We also began the process of identifying risks related to water scarcity and how our operations may be impacted. In 2013, we continued to see significant reductions in water usage and recorded another absolute reduction. We surpassed the 30% reduction goal set in 2011. We are leveraging this success by finding new and innovative ways to increase our water usage efficiency redirecting high quality waste water from ultra-pure operations and investigating opportunities such as rainwater harvesting for gray water use.

Goal

30% Efficiency Improvement by 2015

Water Numbers

USAGE SALESDOLLARS/

m3 OF WATERINTENSITY

IMPROVEMENT2010 1,905,056 $2,271,000,000 $1,192.09 Baseline2011 1,895,131 $2,505,000,000 $1,321.81 11%2012 1,842,510 $2,623,000,000 $1,423.60 19%2013 1,731,175 $2,704,000,000 $1,561.94 31%20142015 $1,549.72 30% Goal

Since 2009, Sigma-Aldrich has reduced water usage by almost

650,000m3 year over year, or a total of 1.9

million m3 from our 2009 baseline over the past four years.

90%of Sigma-Aldrich’s water use comes

from municipal water supplies, while the rest comes from independent surface and groundwater sources.

Sigma-Aldrich does not have any significant discharges of water or runoff that affects the biodiversity value of water bodies and related habitats.

Progress


EN8, EN26


WATER SAVINGS PROJECTS:HOW WE DID IT

St. Louis, MO, USAIn 2013, Sigma-Aldrich successfully completed a project that (i) eliminated single pass water at our DeKalb facility for cooling walk-in refrigerators and freezers and (ii) maximized the efficiency of our cooling towers through adjustments to and replacements of older systems. By looping the water through our systems multiple times we significantly reduced our water usage at the largest user of water in our portfolio.

Water ScarcityTo better understand our water usage and potential water related risk, Sigma-Aldrich mapped each Production and R&D site using the WRI Aqueduct tool. Through this analysis we determined that 74% of our sites are in areas that are considered low risk for water scarcity, 14% of our facilities are considered to be in areas of medium to high risk for water scarcity and 12% of our facilities are considered to be in areas of high to extremely high risk for water scarcity. The facilities in high risk areas have limited water dependent production requirements. Of our Top 10 water using sites, only our 9th largest water user, which makes up 2% of our total water usage, is considered to be in a high risk area for water scarcity.

2012

2013 High risk 11% 12%

Medium risk 14% 14%

Low risk 75% 74%

Global Water UsageReported in m3

PROJECT COST

200,000U.S. dollars

PROJECTED ANNUAL SAVINGS

105,000cubic meters

35,000U.S. dollars

BIODIVERSITY HOTSPOTS

17%of our facilities are located in designated

biodiversity hotspots, but account for only 6.3% of our total CO

2 emissions and 3% of

our total water use.

Rio de Janiero, Brazil; Carlsbad, California; Jerusalem and Rehovot, Israel; Hokkaido, Ichikawa, Ishikari, Osaka and Toyko,

Japan; and Singapore.

Sigma-Aldrich does not have any locations in habitat protected or restored areas.

Brazil 8,351.86 Canada 1,435.26 China 7,503.72 France 1,535.78 Germany 7,656.24 India 38,226.00 Ireland 42,303.00 Israel 25,847.09 Japan 5,133.27 Mexico 176.67 Russia 231.00 Singapore 128.63 Sweden 5,895.43 Switzerland 238,290.94 Taiwan 18,555.68 UK 59,590.13 US 1,265,953.69

EN9, EN11, EN12 , EN13


GC1015 GOAL #4ENERGY EFFICIENCY

In 2010, Sigma-Aldrich committed to a 10% reduction in energy use intensity by 2015 as part of our GC1015 Initiative. The Company subsequently increased that goal to a 20% intensity improvement by 2015. Our ability to reduce the intensity of our Scope 1 and 2 carbon footprint is directly tied to our ability to increase the efficiency of our operations. In 2013, Sigma-Aldrich realized a significant achievement with our first absolute reduction in electricity usage. We did, however, see a significant increase in natural gas usage. Our data confirms that this increase can be directly tied to unusually cold weather for two months of 2013 in North America, where a significant portion of our physical assets are located. In 2013, our electricity usage decreased by more than 4,000,000 kWh resulting in an absolute reduction of 2%. Our natural gas usage increased by approximately 1,000,000 therms resulting in an increase of 11%. Without the two months of weather related increase, in 2013 Sigma-Aldrich would have used approximately 500,000 therms less of natural gas.

Goal

20% Efficiency Improvement by 2015

Sigma-Aldrich used a total of

558,188,000 kWh of non-renewable energy in 2013.

6,623gigajoules of energy will be saved

by Sigma-Aldrich’s energy efficiency retrofit projects in 2013.

114,000 kWh or .0004% of our total

electricity usage is generated from renewable sources.

Progress

10%Intensity Improvement through 2013

50%

EN5

Electricity Numbers

USAGE SALES

DOLLARS/kWh OF

ELECTRICITYINTENSITY

IMPROVEMENT2010 240,030,942 $2,271,000,000 $9.46 Baseline2011 252,329,159 $2,505,000,000 $9.93 5%2012 256,878,051 $2,623,000,000 $10.21 8%2013 251,206,713 $2,704,000,000 $10.76 14%20142015 $11.35 20% Goal

Natural Gas Numbers

USAGE SALES

DOLLARS/THERM OF

NATURAL GASINTENSITY

IMPROVEMENT2010 9,007,069 $2,271,000,000 $252.14 Baseline2011 9,332,342 $2,505,000,000 $268.42 6%2012 9,066,293 $2,623,000,000 $289.31 15%2013 10,036,357 $2,704,000,000 $269.42 7%20142015 $302.56 20% Goal

SALES DOLLARS/kWh OF ENERGYYEAR

Overall EnergyNormalized to sales

Overall Intensity Improvement


10 FACILITIES PROJECT

One of the strengths of Sigma-Aldrich’s Environmental Sustainability platform is our ability to generate meaningful data on our impact on the environment. After analyzing that data, we announced our 10 Facilities Project. This project focuses on energy efficient investments intended to reduce our electricity usage. We found that more than 60% of our energy usage was centered at 10 of the largest facilities in our portfolio. Of those 10 facilities, eight are in the U.S. We believe we can invest in energy efficiency projects while still achieving our ROIC expectations at these 10 facilities. We are targeting a 6% reduction in electricity usage at these facilities and expect to see the full results of these investments in 2015/2016. This reduction would be the equivalent of a more than 6,000 metric tonne CO

2 reduction. During

this period, we hope the offset in energy use will help mitigate growth in our CO2 footprint

that we expect from the opening of an additional facility in Irvine, Scotland, as well as increased production capacity at one of our St. Louis facilities.

DIRECT ENERY CONSUMPTION BY PRIMARY SOURCE

1,066,730 GJ Natural Gas15,656.4 GJ Kerosene

10,249.2 GJ LPG 7,016 GJ Diesel133 GJ Fuel Oil

INDIRECT ENERGY CONSUMPTION BY

PRIMARY FUEL SOURCE909,687.6 GJ Electricity

20,941.2 GJ Steam23,486.4 GJ Delivered Heat

Sigma-Aldrich invested more than

$306,750in energy efficiency programs that will

save $94,200 and 1,269 metric tonnes of CO

2.

Global Electricity UsageReported in kWh

Global Natural Gas UsageReported in therms

China 1,860,853Germany 9,038,636India 2,917,579Israel 13,137,218Switzerland 7,887,335Taiwan 3,060,642United Kingdom 18,857,077United States 165,133,440

EC8, EN3, EN6, EN19

Brazil 27,809Germany 141,895Ireland 446,762United Kingdom 773,069United States 8,564,632


ENERGY EFFICIENCY PROJECTS

St. Louis, Missouri, USAWe completed several energy efficiency projects, including the installation of the first solar array at our Corporate headquarters. Engineers also optimized our building management system to institute higher setback temperatures during the weekends to reduce the need for conditioned air.

Buchs, SwitzerlandThe Swiss government introduced a program to reduce energy usage by 2% annually. The Buchs site, which is one of our larger production facilities, began the process of identifying investments and initiating projects. The first projects that were undertaken at the facility included updates like new energy efficient windows, the replacement of roof insulation with a higher r value and optimizations of the use of compressed air at the site.

Bangalore, IndiaOur engineering team in Bangalore installed timers for our air handling units in the warehouse. This inexpensive update helps reduce the number of hours each air handling unit runs by 28 hours each month.

COST

$74,000COST

$90 ENERGY SAVINGS

379,000 kWh

ENERGY SAVINGS

10,080 kWh

ENERGY SAVINGS

1,143,000 kWh

CO2 SAVINGS

261metric tonnes CO

2

CO2 SAVINGS

71metric tonnes CO

2

FINANCIAL SAVINGS

$103,568FINANCIAL SAVINGS

$1,800FINANCIAL SAVINGS

$1,300


GC GOAL #5SUPPLY CHAIN TRANSPARENCY

Goal Top 100 Suppliers Surveyed by 2012

Top 200 Suppliers Surveyed by 2015

Progress

50%

We continue to see increasing inquiries from our customers regarding the transparency of our supply chain. In 2013, Sigma-Aldrich took another step to communicate the expectations of our business and supply chain partners with the release of our Supplier Code of Conduct (SCOC). This Code shares our expectations regarding Environmental, Social and Governance (ESG) management. The introduction of the SCOC is just the initial step in our engagement with suppliers. Our three phase approach to supplier engagement also includes the introduction of a sign off on the supplier’s commitment to sustainability by a senior supply chain leader of all our suppliers. This step is meant to further ensure that our expectations are communicated to the leadership of our supply chain partners and that they provide confirmation that these expectations are being met. We also plan to incorporate ESG factors into our supplier audits to increase our confidence with our surveying. These onsite audits will begin to happen in 2015. Our goal is not just to survey suppliers, but to encourage dialogue and action to create active social and environmental improvements. This mission has been divided into three phases.

Sigma-Aldrich’s Supply Chain focuses on SQDIC+P. The approach focuses on Safety, Quality, Delivery, Inventory, Optimization and People. There are more than 5,000 Global Supply Chain employees at Sigma-Aldrich that focus on Planning, Procurement, Quality Assurance and Control and Distribution.

G4-12


THREE PHASE APPROACH

3. Active Improvement2014-2015

The final phase will hold each supplier accountable for taking active measures to improve their environmental and social impact. We will set goals collectively for our entire supplier base and then regularly assess progress toward these goals. We will support our main suppliers, working collaboratively with them to continually improve performance. To support the Global Citizenship Initiative and our Supply Chain goal, we created a Supplier Code of Conduct (SCOC) that was released to our suppliers in 2012. The SCOC informs suppliers of our expectations, which were created using principles from the United Nations Global Compact and the International Labor Organization. The Global Citizenship department is working with both Procurement and Quality to implement supplier expectations. The SCOC outlines the standards we hold suppliers to in the following areas:

• Labor Standards

• Environmental Performance and Management

• Health and Safety Practices

• Compliance with Laws

• Ethics

• Fiscal Responsibility

• Fiscal Responsibility

Our goal is not just to survey suppliers, but to encourage dialogue and action to create active social and environmental improvements. This mission has been divided into three phases.

1. Reporting2010-2012

Complete

This phase included the SA7 questionnaire response period, where we collected data from our current suppliers then tracked and analyzed data related to environmental and social impact and whether they have established goals for improvements.

Findings

Of the 100 Suppliers surveyed, more than 75% responded within the requested timeframe. We identified nine suppliers that require further follow-up to understand what policies have been implemented; their capability to track ESG related information and potential plans to do so. At the end of 2012, no supplier responses required immediate action because of violations of the Supplier Code of Conduct.

2. Current Impact2013-2014

In Progress

After establishing an expectation for transparency and data availability, we are now assessing the current environmental and social impact of each supplier based on their reported data. Using this information, we can determine risk profiles for each supplier and whether further action and engagement is necessary. The creation of our supplier risk matrix guides educated decisions that enable us to operate in a more socially and environmentally conscious manner. The risk profiles are a key aspect to consider when making decisions on future purchases with suppliers. The profiles also form the basis for dialogue with our suppliers regarding performance expectations. There were no new suppliers screened in addition to those outlined in our Supplier Transparency Initiative.

EN32, EN33, LA14, LA15, HR4, HR5, HR6, HR10, HR11, SO9, SO10


SUPPLY CHAIN UPDATES

UN Global CompactIn July of 2013, Sigma-Aldrich filed its first Communication on Progress for the UN Global Compact. Our signature to the UN Global Compact is a public commitment to uphold Human Rights, Labor Rights, Environmental Protection and Anti-Corruption principles. Sigma-Aldrich’s policies and approach to these four topics aligned with the United Nations goal of ensuring that markets, commerce, technology and finance work to benefit economies and societies everywhere. Sigma-Aldrich is proud to have adopted internationally accepted framework which serves as guiding principle not only with respect to our employee engagement initiatives, but also with our suppliers. For more information on the UN Global Compact, please visit www.unglobalcompact.org.

Procurement and Supply Chain UpdateEach year the Global Procurement, Global Planning and Freight teams at Sigma-Aldrich work to make our supply chain stronger and more efficient. Our teams execute individual department projects and also partner on cross-functional projects as well as projects with our suppliers to gain a better understanding of how we can mutually benefit from increased information sharing regarding business trends and order demands.

Air to Ocean UpdateIn 2013, we once again realized significant improvements and gains from our Air to Ocean project. By analyzing all of the ocean routes we use to move product and raw materials, starting with shipments leaving our Teutonia facility in Milwaukee and following the shipments to their final

destination at our Schnelldorf facility in Germany, we were able to implement significant reductions in total transit time; from approximately 30 days to 19 days. This reduction in transit time allows us to ship more of our slow selling products via ocean, a less expensive and more environmentally friendly alternative to air transport, without having to worry about back-orders or service issues for our customers. Some of the operational changes we made include loading the container on site versus consolidating at a freight forwarder and trucking our containers directly to the port in New York. The successful extension of this project to our SAFC Commercial Business Unit enabled us to significantly reduce Scope 3 emissions for upstream transportation and distribution; total reduction in 2013 was 1,900 tonnes as compared to 701 metric tonnes in 2012. We plan to continue our focus on optimization of materials and product transportation through the evaluation of other potential opportunities to move freight by ocean rather than air.

Virtual BoxingThis past year we extended our Virtual Boxing initiative to our third largest distribution center in Allentown, Pennsylvania. This project utilizes our enterprise management system to identify packing optimizations that reduce the number of boxes that must be used to ship products based on product packaging combinations that are in compliance with governmental regulations for the shipment of our products. We estimate the total reduction in the number of boxes in 2013 due to Virtual Boxing was 33,000 which is equivalent to a reduction of 132,000 lbs. of cardboard.

Sigma-Aldrich does not transport its products to customers directly. We use a number of carriers and freight forwarders to gain economies of scale in large shipments, both domestically and internationally. Because of the potential risks associated with some of our products, the carriers and forwarders with which we contract must follow industry best practices and international guidelines regarding the shipment of our products. In addition we use all of the product data we can obtain to make sure we comply with international GHS and transportation requirements as a means of protecting against the health and environmental risks of transporting dangerous goods.

G4-15, HR1, EC9, EN30


Packaging Solutions That Reduce Our ImpactPackaging of our products is one of the most important jobs that we have at Sigma-Aldrich because of our focus on safety. We continually seek out new, safe, less expensive and more environmentally friendly packaging solutions. All solutions must pass stringent tests that ensure the products will arrive at their destination without breaking or leaking. Our procurement and packaging engineering teams partnered in 2013 to identify two new packaging improvements. The first improvement was a molded pulp insert for our 4x4 liter solvent packages. This new solution utilizes 100% recycled pulp that is then molded to fit the top and bottom of our four liter solvent bottles. This packaging innovation provided two benefits: first, products are more secure because the new solution reduced the likelihood of shifting during transportation because of the custom fit; second, was the absolute reduction of packaging waste. This solution eliminated the need for 2.1 lbs. of cardboard per 4x4 liter solvent package, that had been used to secure the bottles in the larger shipping box. We estimate that the annual reduction of cardboard in these packages will be 241,500 lbs.

2.1lbs. of cardboard per box

241,500lbs. annual reduction

The second packaging change was the elimination of the use of polystyrene peanuts at our largest Central Distribution Center in Milwaukee. A new air pillow solution was introduced that is compostable or recyclable based on available facilities. The air pillows will eliminate the use of 210,000 cubic ft. of polystyrene peanuts, which has been consistently one of the biggest complaints of our customers. We are evaluating the potential roll-out of this solution to our other distribution centers with a goal of completely eliminating polystyrene from all of our U.S. distribution centers by 2016.


Small Business/Supplier DiversitySigma-Aldrich works to provide small business concerns, including veteran-owned small businesses, service-disabled veteran-owned small businesses, HUBZone small businesses, small disadvantaged businesses and women-owned small businesses the maximum practical opportunity to compete for the sale to us of goods and services.

This commitment extends to the procurement of goods and services according to our Procurement policy, whether the purchases eventually support sales under Sigma-Aldrich’s General Services Administration (GSA) Multiple Award Schedule (MAS) Contract, sales to state or local governments, sales to academic or other industry customers or in-house needs.

We are committed to maintaining an effective supplier diversity program that is consistent with contractual expectations, that maximizes procurement opportunities for Small Business Concerns to the fullest extent and is consistent with efficient performance.

In 2013, Sigma-Aldrich was able to increase its SBE expenditures to 11.8% of total spend by continuing to focus on relationship building with Small Businesses enabling these vendors to more easily communicate to our Procurement professionals with information on the goods and/or services they offer. Additionally, 20.7% of the procurement budget for our most significant locations was used on purchases from local suppliers.

Conflict MineralsThe Company is aware of the obligations set forth in the Dodd-Frank Wall Street Reform and Consumer Protection Act with respect to the sale or use of tantalum, tin, tungsten and gold (the “Minerals’) that have been extracted from the earth in the following countries: Angola, Burundi, the Central African Republic, Democratic Republic of the Congo, the Republic of the Congo, Rwanda, South Sudan, Tanzania, Uganda and Zambia (the “Covered Countries”).

The Company does not knowingly source, directly or indirectly through its suppliers, any of the Minerals from Covered Countries or any product that contains any of the Minerals from Covered Countries that contribute to armed conflict or human rights abuses. The Company requires the same commitment from its suppliers through its Supplier Code of Conduct, Purchase Order Terms and Conditions and form Supply Agreement.

The Company annually conducts a reasonable country of origin inquiry in order to provide reasonable assurance that its suppliers do not supply to the Company, directly or indirectly from their own suppliers, any Minerals from Covered Countries that contribute to armed conflict or human rights abuses. If the Company concludes that a supplier has sourced, directly or indirectly, any Minerals from Covered Countries that contribute to armed conflict or human rights abuses, the Company immediately discontinues such procurement activities with said supplier. Any such supplier will be placed on a watch list and, should further sales of Minerals by any such supplier be made or attempted, the Company may discontinue all procurement activity. Sigma-Aldrich will publish its findings annually regarding Conflict Materials and the supply chain.

100% of our purchase orders and contracts reference our standard terms and conditions and/or our supplier code of conduct. Our standard terms and conditions are referenced in our purchase orders and the supplier code of conduct is referenced in our contract templates. Our standard terms and conditions require compliance to our supplier code of conduct which includes human rights clauses.


GC1015 GOAL #6GREENER ALTERNATIVE PRODUCTS

As part of our GC1015 Initiative, Sigma-Aldrich committed to increasing the sales of our Greener Alternative Products, while also focusing on enhancing the information we provide to our customers on why a product is considered a greener alternative. We continued to fine tune our approach in 2013 clarifying three categories of Greener Alternative Products:

1. Re-engineered Products

2. Aligned Products (products that meet one or more of the 12 Principles of Green Chemistry)

3. Enabling Products Products are now identified on the Sigma-Aldrich website with an icon that is displayed in search results and on product detail pages. Each product that has this icon also has a documentation source with peer reviewed published information on why it’s green.

SIGMA-ALDRICH GREENER ALTERNATIVE PRODUCT SALES

14.4% total increase

Goal

25% increase in sales of our 2,563 Greener Alternative Products

Progress

56% 3.9%sales increase in 2013


Providing our customers with a broad range of greener alternatives to help them accomplish their research, while reducing their environmental impact, has become a larger area of focus in the past year. To guide our efforts, we identified three key areas of products designed to meet those needs. Those three categories are:

Re-engineered ProductsProducts that are in the re-engineered category are those products that are manufactured by Sigma-Aldrich. Members of the Worldwide Green Chemistry Committee have developed new ways to manufacture the products that use fewer resources, are less hazardous and/or generate less waste.

Aligned ProductsThese products demonstrate one or more characteristics that align with the 12 Principles of Green Chemistry. Examples of these products include a new line of products from one of our supply chain partners – Biomatrica®. The ambient storage technology of this company enables sample storage without the need for ultra-low-temperature freezers aligning with Green Chemistry Principle # 6 “Design for Energy Efficiency.”

Enabling ProductsEnabling products are those that enable the research of alternative energy. Products from the Sigma® Life Science and Aldrich® Materials Science portfolios are being used by scientists in novel ways to help find new solutions to unlock the power of nature through biofuels or other nanotechnologies. Our Materials Science Portfolio includes a wide variety of novel and tested materials used for energy generation, storage, and efficiency. This portfolio includes a wide variety of small-molecule chemicals, polymers, nanomaterials, as well as metals and ceramics. Sigma-Aldrich maintains a number of collaborations with leading universities to develop and test the latest in alternative energy materials, and is a leader in making these materials available to the research community as well as in assisting with the commercialization of new technologies.

SIGMA-ALDRICH GREENER ALTERNATIVE PORTFOLIO


Our goal of providing consumers with safe, efficient and environmentally responsible products starts with making sure that our customers receive full disclosure as to why certain products may be more sustainable than others. We’ve begun the process of developing an achievable and reasonable quantitative standard in our industry that clearly delineates a product’s environmental impact. A consistent and easy-to-understand system is an important tool to help scientists and consumers make informed decisions about “greener” products.

How to Quantify Greenness?To address our customers’ questions regarding how we quantify “greeness,” we created a system that determines the relative “greenness” of a product using the 12 Principles of Green Chemistry as a framework. This system has generated interest from those of our customers who have been introduced to our Sigma-Aldrich Greener Alternative Products (GAP) Index. The index uses the 12 Principles of Green Chemistry as a framework. Each Principle has a corresponding algorithm that utilizes Globally Harmonized System (GHS), Material Safety Data Sheet (MSDS) and Manufacturing Data. The scores for each Principle are weighted and averaged to create a final aggregate score as shown below.

N-Benzoyl-L-Threonine Methyl Ester, Product #281107

12 PRINCIPLES OF GREEN CHEMISTRY *

1. Waste Prevention

2. Atom Economy

3. Less Hazardous Chemical Syntheses

4. Designing Safer Chemicals

5. Safer Solvents and Auxiliaries

6. Design for Energy Efficiency

7. Use of Renewable Feedstocks

8. Reduce Derivatives

9. Catalysis

10. Design for Degradation

11. Real Time Analysis for Pollution Prevention

12. Inherently Safer Chemistry for Accident Prevention

SIGMA-ALDRICH GREENER ALTERNATIVE PRODUCT INDEX

*Anastas, P. T.; Warner, J. C. Green Chemistry: Theory and Practice, Oxford University Press: New York, 1998, p.30.

HOW THE PRODUCTION OF N-BENZOYL-L-THREONINE METHYL ESTER WAS IMPROVED

• Product yield increased from 21.3% to 91.5% in the new process.

• 50% reduction in the total mass of the materials used

• Waste generation was cut by 50%

In 2013 we completed the update to our scoring methodology and will be publishing the scores of our products in 2014. As our Worldwide Green Chemistry teams continue to re-engineer products, we will add those products and their respective scores to our website. We are also working with suppliers to test a model that would enable us to score products manufactured by supply chain partners. We have begun the process of weaving this methodology into the introduction of new products so we can evaluate the environmental footprint of products during R&D. Sigma-Aldrich is committed to leadership in Green Chemistry and we are achieving this by providing scientists with a wide range of information and products that enable the practice of greener research. We know that the multiplier effect of our efforts is large. If we can reduce the impact of the starting materials in research, the scale up and manufacturing of the products resulting from that research is that much more efficient and produces a much smaller environmental footprint.

SCORING MATRIX0 = most desirable

82% improvement

PREVIOUS SCORE

21NEW

SCORE

4


Greener Process for the Synthesis of 1-Aminobenzotriazole (A3940)Striving continuously for process improvements, the long, complicated and hazardous four step synthetic process of 1-Aminobenzotriazole (A3940), a Cytochromic inhibitor, was successfully improved to a one-step synthesis that resulted in higher product yield, significantly improved safety, cost savings and reduced environmental impact.

HIGHLIGHTS AND ADVANTAGES

• The hazardous hydrogenation procedure at atmospheric pressure using 10% Pd/C in Methanol (20 L flask) eliminated from the process

• 40% less organic solvents

• Eliminated about 6 L of Conc. HCl and 150 g of 10% Pd/C catalyst

• 6 kg less auxiliaries, e.g. Sodium acetate/carbonate/sulfate

• Cycle time reduced by 73%

• Product yield increased by about 60%

Greener Process for the synthesis of 4-Acetylbenzonitrile (154393)

Sigma-Aldrich produces 4-Acetylbenzonitrile in a range of 2-3 kg per year. Previously the production was performed by reaction of 4’-Bromoacetophenone with toxic Copper(I) cyanide in refluxing DMF. The procedure was changed to a Palladium-catalyzed cyanation reaction with nontoxic Potassium hexacyanoferrate as cyanide source.


• Replacement of toxic Copper(I) cyanide by nontoxic Potassium hexacyanoferrate

• Improvement of yield from 46 to 64%

• Scalable to pilot plant instead of requiring multiple batches

• Avoidance of copper bromide waste and waste water contaminated with copper salts

• Reduction of reaction temperature from 168 °C to 120 °C

PRODUCT INNOVATIONS

Improvement of Epoxidation ReactionUntil now the epoxidation of an alkene was performed with peracetic acid. This process had several drawbacks including very long reaction times (>3 d), accumulation of peroxide in the reaction mixture and several distillations required during the work up. This reaction was further investigated and an efficient greener epoxidation reaction using 3-chloroperbenzoic acid was developed.


• The original process had major safety hazards of forming peroxides using peracetic acid at elevated temperature. This was eliminated by using 3-chloroperbenzoic acid at room temperature

• Purity of the crude product formation was increased several folds with controlled addition of the reagent which reduced multiple distillation steps and reduced energy use requirements

• 7,300 kg of a chlorinated solvent, dichloromethane, was recycled to use in subsequent batches

• Cycle time was reduced more than 50%

Greener Process for N-Maleoyl-β-Alanine (394815)

This product was taken for development in order to improve the yield and minimize the hazardous waste generation. The new synthetic route minimizes the use and generation of hazardous substances. The three step route is modified into a single step which entails easily accessible and cheaper raw materials and the product is produced within 2 hours with an improved yield.


• 96.4% reduction in reaction cycle time and 85% reduction in raw material cost

• Yield increased by 85% when compared with old process

• ~55% reduction in solvent and reagent usage

• More than 85 % reduction in total mass of the materials used which directly impacts waste production

• Eliminated the use of chlorinated solvents (Dichloromethane) and carcinogenic solvents

• Large quantity of aqueous acidic waste generation eliminated

EN27


Greener Process for the Synthesis of 5β-Pregnane-3α,20α-diolThis product is used as an intermediate raw material for product 5β-Pregnane-3α,20α-diol glucuronide [P3635]. As per the old process, the reaction was done in 5 lots with sodium metal and Isopropanol under reflux conditions. During purification the crude products from all lots were combined and recrystallized with acetone. Desired chemical and chiral purities were obtained in tedious six crystallizations with very low yield. The new route was designed to synthesize the product in a single batch. The reaction was carried out at 5-10°C and reaction completed within 2 hours.


• Eliminated the usage of sodium metals

• Cycle time reduced more than 70% with ~90 % reduction in total usage of the solvents, which directly impacts the waste stream reduction

• Yield 72 % (new process) versus 22-45% (old process)

• Reaction temperature and time are considerably less in new process and making it more energy efficient


PrivacyThe Company is subject to various laws and regulations around the world that require us to hold in confidence and use only for specified purposes certain types of personal information such as government insurance (example: Social Security) numbers, medical or financial data or information about children. In addition, as a participant in Safe Harbor programs with the European Union and Switzerland, the Company is required to adhere to principles concerning the processing of personal information of EU and Swiss residents. We endeavor to protect personal data received from any source in accordance with “Key Principles” that are similar to the requirements of European Union and Swiss privacy laws and Safe Harbor programs as well as similar privacy regulations in other countries in which we operate. Generally speaking, these Principles and this Policy give those whose personal information we collect the right to consent to the collection, use and disclosure of such information, the right to opt-out of any such collection or use and to require the Company to correct inaccurate personal information that the Company maintains. They also require the Company to maintain physical, organizational and technical safeguards to protect personal data from unauthorized access, use, alteration or disclosure and require that third parties that process personal data on our behalf also comply with these obligations.

IT Security PolicyThe Company is committed to the permanent privacy of all employees, customers, contractors and visitors both externally and internally. The IT Security Policy creates clear rules for handling and processing classified information and requires all information and IT resources to be available and treated with confidentiality and integrity while adhering to all legal regulations and contractual agreements. To balance the needs of IT security rules and requirements with the needs of the Company to exchange and access information quickly, the Company established a set of security principles and implemented an IT Security Policy. The IT Security Policy establishes a comprehensive global security standard and unified process that is the standard for Company actions at all locations. The Information Security Management System (ISMS) outlines security processes and details the responsibilities and duties for all Company employees globally. The Company works to ensure information security and protection for all forms of information and protects personal information according to the respective national legislation. The Company regularly assesses the state of global IT security and takes preventative actions to avoid potential IT security risks.

We received no complaints regarding breaches of customer privacy or losses of customer data in 2013.

In 2013, there were no incidents of non-compliance with regulations or voluntary codes concerning marketing communications, including advertising, promotion or sponsorship.

Sigma-Aldrich uses recycled paper for technical bulletins included in our products.

MARKETING

PR7, PR8


GLOBAL CITIZENSHIP AWARDS 2013

Each year Sigma-Aldrich recognizes those employees who made significant contributions to the Sigma-Aldrich Global Citizenship program. From R&D initiatives within the Green Chemistry project, to energy and water efficiency improvements at our facilities and outreach initiatives that benefit our communities, with the full support of our dedicated team of employees around the world, our internal innovations and external partnerships continue to advance Sigma-Aldrich’s mission of enabling science to improve the quality of life. In 2013, the slate of nominees grew once again in the depth and impact of their projects, ranging from new packaging solutions that significantly improved the environmental footprint of our shipments to reductions in air shipments through the Air to Ocean Project and new innovations in greener chemical replacements and substitutions. Judged on five criteria – Originality/Innovation, Cost Savings, Green Technology, Customer Impact and Internal Impact – the Global Citizenship Award nominees each have made significant contributions that align with one or more of the goals of our Global Citizenship program. The awards are judged by an internal panel, who largely based their evaluation on demonstrably quantitative impacts of the nominated activities such as hazard reduction of a product, miles biked, or volunteer hours donated. The 2013 nominees saved the Company, in the aggregate, more than $1,200,000 through their projects, in addition to increased energy savings and decreased material and waste disposal costs. Cash prizes were awarded to the first, second and third place projects.

2013 Global Citizenship Award Winners Kristin Blum, Shelley Coleman, Rob Deeks, Matt Fiedler, Ken Goldstein, Martin Gordon, Peter Guettinger, Matthias Jaeger, Tina Montgomery, Jason Noll, Mark Reinholz, Rob Ricci, Jim Scadden, Konrad Siczek and Tobin Sykes

Air to Ocean Project

Our freight and planning teams continued to expand the Air to Ocean Project by identifying more Research and Applied products that can be best transported globally via ocean freight. This has lead to a significantly lower carbon footprint compared to air freight. The main challenge the team faced is transit time and the impact this has on ensuring we meet our delivery commitment to customers. Through the optimization activities the team introduced, the number of days freight is in transit by ocean decreased by 11 days. The project delivered significant savings, both financially and environmentally, reducing CO

2 by more than 1,500

tonnes. Martin Gordon, a team member from our SAFC Commercial Business Unit, utilized the framework of this project for the SAFC Commercial Business Unit and was able to reduce carbon emissions by 400 metric tonnes. Combined, these two projects helped reduce our Scope 3 carbon footprint by almost 2,000 metric tonnes.

From 2009 to 2013, Sigma-Aldrich Global Citizenship Projects have

reduced costs by more than

$7.5M


2nd PlaceJill Jacobsen-Kent, Carrie Ann Haver, Aleks Zikovic, John Irving, Jason Noll, Stacy Kingston, Brandon Finger

Packaging Enhancements

In 2010, the team initiated a study to begin using air pillows in packaging to reduce the use of polystyrene peanuts. Following several successful tests, the team fully implemented the solution in 2013 and eliminated the use of 210,000 cubic ft. of polystyrene peanuts annually. In 2013, another new packaging solution was introduced for the 4x4 L solvents. This new molded pulp solution uses 100% recycled material to create the shipping material and due to the molded shape it protects the packages better. This new solution reduces the need for 241,500 lbs. of corrugate annually.

3rd Place – TieShlomo Sayag, Malka Gebel, Inbal Aped, Evgina Levin, Israel Sherfstein, Efrat Manaster, Itzhak Ergaz

Synthesis for 1-Aminobenzotriazole

This team redesigned the process to produce this product from a four step synthesis to a single step, cutting the work time by 22 days per batch. The new process also eliminated the use of many hazardous chemicals, including a Pd/C reaction and reduced the use organic solvents needed for the procedure by 40%. The yield of the new process increased approximately 60% over the old one.

Hari Kota

Beneficial Reuse

Hari diverted 15,545 lbs. of material from the waste disposal process. By researching and identifying 15 different materials that could be reused, sold back to vendors, or recycled, more than 11,000 lbs. of CO

2

emissions were saved.

Honorable MentionTomislav Reiss, Stauffer Ramona, Edi Thurnheer

Improvement of 1,2,7,9-Diepoxyoctane Synthesis

Michael Poelzel

Firebridgade Partnership

Chris Komo

St. Louis Corporate Headquarters Solar Array

Sherri Williams

Stretch Wrap Recycling Project

Dayanand Andalaiah

Multi-Page Invoice Optimization

Beth Shepard

Food Drive Leadership Coordination

Eric Thietry, Patrick Guilet, Bernard Ramier, Jonathan Peixoto and Frederic Pelisson

Biodegradable packaging solution

Bangalore, India Lab Operations

Community Science Education Initiative

Mahantesh Kumbar

Synthesis of N-benzoyl-threonine Methyl Ester

Palaniraja Subramaniam

Improved production of 5β-Pregnane-3α,20α-Diol

Rajitha S

Reengineered 1,1,3,3-Tetramethylbutyl Isocyanide

Ramesh Boddiboyena

New process for production of N-maleoyl-β-alanine

Sanju Walikar

Re-engineered the procedure for manufacturing (+/-)-Diethyl Trans-4-Cyclohexene-1,2-Dicarboxylate

Sreegantharaja Raman

New procedure for 2-Phenyl Pyridine


What if a 12 year old learned to love science? We started with a simple question: what if science changed the world? On a basic level, it already has; science has enabled us to make unimaginable discoveries in areas that touch our lives every day. However, this question is still relevant today –for the twelve year old who was inspired by learning about electrolysis for the first time; the scientist working on a breakthrough malaria treatment; and the thriving science start-up on the brink of launching its first product.

Asking this question and many other “What if” questions carried our employees through 2013 with a desire to find the answers and a passion to make a difference. From running in charity races to raising money for cancer research in the UK, to teaching science to school children in Bangalore, India; Sigma-Aldrich employees gave their time, money and expertise to help science change the world.

It was this drive that made 2013 another successful year for social responsibility at Sigma-Aldrich. Our employees volunteered more than ever before, we solidified our charitable giving strategy and we engaged more of our employees around the world. Team Sigma-Aldrich launched in 6 additional countries and employees participated in more events than in previous years keeping us on track to reach our GC1015 social responsibility goal.

2013 also brought about two firsts at Sigma-Aldrich: the largest coordinated Team Sigma-Aldrich effort to date – the Sigma-Aldrich Global Food Drive, which engaged thousands of employees and resulted in the donation of tens of thousands of pounds of food to hunger relief organizations, and the launch of the Sigma-Aldrich Science Partners program.

SOCIAL RESPONSIBILIITY


GC1015 GOAL #7TEAM SIGMA-ALDRICH

In 2013, we made strides to achieve our Team Sigma-Aldrich GC1015 goal by continuing to expand the program globally and by engaging more employees than ever before. Employees from 17 countries and 31 sites participated in more than 70 community events supporting a wide range of causes.

As with previous years, we saw an increase in all three of our key indicators: number of participants, dollars donated and volunteer hours. The biggest jump was seen in the hours our employees volunteered, which increased by more than 40% from 2012.

This growth was coupled with a continued focus on identifying opportunities that align with our three charitable funding areas and also met the needs and interest of our employees. By engaging our employees in activities related to their skillsets, we were able to provide more robust and rewarding experiences for them and to better serve our partner organizations.

To assist our employees in finding volunteer opportunities in their respective cities, we began to develop the Sigma-Aldrich Volunteer Portal. The Volunteer Portal will allow our employees to track their volunteer hours, find local volunteer opportunities and learn how their colleagues are getting involved around the world. The portal is scheduled to launch in 2014.

72events

31sites

Goal Team Sigma-Aldrich in all 37 countries with operations

4.0 volunteer hours per employee

PARTICIPANTS

3,547 31%

EMPLOYEE DONATIONS

$200,294 29%

VOLUNTEER HOURS

8,056 41%

Progress

46%17Countries

.90 Hours/Employee

CORPORATE PHILANTHROPIC FOCUS

STEM Education

Scientific Research

Economic Development through Science


EMPLOYEES GIVING BACK

MarianMAKING THE CUT FOR A GOOD CAUSE

Marian Traves, a Sigma-Aldrich employee from Bromborough, UK, went to great lengths for charity. In 2014, Marian will celebrate her 50th birthday and committed to raising more than £5000 for local charities in honor of the occasion. Marian held grassroots charity events such as bake sales, raffles and walks to reach her goal. Marian didn’t stop there though, as a finale she vowed to shave her head – raising more than £1100 as part of the event.

Marian, who works in customer service, split the donations between Duchenne Now, a muscular dystrophy research organization, and Claire House, a hospice that cares for children with serious illnesses. “The son of a close friend of mine has muscular dystrophy, and we are hopeful of a cure in time to save him,” Marian said.

“A lot of people celebrate their birthdays by treating themselves, but Marian celebrated the entire year working to help her community instead,” said friend and colleague Charis Baines. “We are proud to work with such an amazing person who has really shown how much we can all make a difference.”

Marian isn’t done yet though. She has plans to collect books, run in more charity races and hold a bake-off all in the name of giving back to others.

Pro BonoSKILLS-BASED VOLUNTEERING

In 2013, members of the Legal Department partnered with the St. Louis chapter of the Association of Corporate Counsel to facilitate “Street Law,” an initiative designed to help prime the pipeline to the legal profession for young people from underserved high schools in St. Louis. Sigma lawyers presented real life legal lessons and insights on topics such as copyrights, patents and trademarks. Street Law ’s accessible, engaging and interactive programs empower students and communities to become active, legally-savvy contributors to society.

The Legal Department also strengthened its partnership with Legal Services of Eastern Missouri to support entrepreneurs who are low-income and nonprofits serving low income populations. Sigma’s lawyers have provided a wide range of legal assistance including contract drafting and general legal guidance.


Rhonda TimmonsMAKING THE MOST OF RETIREMENT

When Rhonda Timmon’s thinks back on her 33 year career at Sigma-Aldrich, she can’t think of a day she didn’t enjoy, “going into the office never felt like work, I loved what I did and everyone I worked with.” This sentiment provides a glimpse into Rhonda’s fun loving and caring personality and why she still can’t stay away from the Milwaukee, Wisconsin, facility where she spent so many years.

While at Sigma-Aldrich, Timmon’s held more than six positions, from help desk specialist to packaging coordinator. She regularly volunteered during company picnics, retirement parties, employee appreciation days and was a consistent face at charity events. “I’m a people person,” Timmon’s said, “I love having the opportunity to help others and to give back to the community that has done so much for me.”

Though Timmon’s has been retired for two years, she continues to volunteer her time giving back to others. On an average weekend, you’ll find her participating in charity walks supporting any number of causes, from arthritis and breast cancer research to mental health awareness. One of her favorites is the Briggs and Al’s Walk and Run, which supports the Children’s Hospital of Wisconsin. Sigma-Aldrich has supported the event since 1993 – the same year Timmon’s started participating. During the week, Timmon’s spends her time volunteering with former criminal offenders helping them learn the necessary life skills to gain employment.

Timmon’s doesn’t plan on slowing down anytime soon. She’s always looking for more causes to support and other ways to volunteer with her Sigma-Aldrich colleagues


STEM UPDATE

Science is an endless discovery process, with the infinite ability to improve the quality of life. Yet, despite its limitless possibilities many students the around the world have little to no access to quality Science, Technology, Engineering and Math (STEM) education, while many lack the interest or skills needed to obtain a degree or work in STEM-related fields.

To reverse this trend, we have committed a third of our charitable giving budget to STEM education programs around the world. From STEM focused teacher professional development programs to STEM summer camps, we have and will continue to identify and support the most innovative programs. This expertise will not stay local though, we challenge our partner organizations to share their programs, curriculum and knowledge with other STEM organizations around the world to further their impact. The problems concerning STEM education are not local or national, they are a global crisis that will take a global collaborative response – and we are committed to being part of it.

Through our many partnerships, organizations leverage the skills of Sigma-Aldrich employees to bring real world examples into science lessons. We believe that bringing a career connection to learning will only strengthen a student’s understanding and appreciation for science and in the end, we hope this exposure will inspire the next generation of scientists.

In 2013, our employees reached more than

8,000students through STEM programs


In 2012, Sigma-Aldrich began developing its signature skills based volunteer program – Sigma-Aldrich Science Partners. The program will connect our scientists to schools near our facilities around the world. Through interactive, engaging and state standards aligned science lessons, our scientists will bring real scientific experiments into the classroom and in select areas, schools will have the opportunity to travel to a Sigma-Aldrich facility for a more in-depth look into the science we do every day.

Science Partners has a goal of reaching 30,000 students across 15 countries in just five years. All employee volunteers will be trained prior to entering the classroom.

In 2013, ten employees began piloting the program in St. Louis with local schools. Initial results have been promising with more than 75% of students showing increased science knowledge after just one lesson. We will be incorporating feedback and working to improve the program over the next year. Look for an update on the Science Partners program in the 2014 Global Citizenship report.


STEM PARTNERSHIPS AND INVOLVEMENT AROUND THE WORLD

Laramie, Wyoming, USASigma-Aldrich worked with the University of Wyoming to develop a professional development program for teachers focused on STEM subjects. The program primarily works with schools in rural areas of Wyoming where access to science professionals may be scarce.

Round Rock, Texas, USASigma-Aldrich Partners with Girlstart, a community-based informal STEM education organization dedicated to empowering and equipping girls in STEM through year-round STEM educational programming. Sigma-Aldrich employees volunteer during STEM camps and the annual STEM conference.

St. Louis, Missouri, USASigma-Aldrich is a founding member of STEMpact, a collaborative effort of corporations, universities, community organizations and schools that aims to transform the STEM education ecosystem to prepare tomorrow’s professionals and to ensure the vitality of the region’s economy.

Through the STEM Teacher Quality Institute, a two week intensive summer professional development program for teachers and an initiative of STEMpact, more than 230 teachers from 13 schools have been trained. Teachers learn to integrate new technology into their classroom and to re-think lesson development to ensure their students leave as STEM capable learners.

Madison, Wisconsin, USASigma-Aldrich partners with the University of Wisconsin – Madison Institute for Chemistry Education to support a number of University-wide STEM education initiatives including the SciEncounters program, which sends University students and Sigma-Aldrich employees into Boys and Girls Clubs to teach STEM education.

Rockville, Maryland, USAIn partnership with Johns Hopkins and Shady Grove Hospital, Sigma-Aldrich supports the Frontiers in Science program, which provides middle school students the opportunity to learn from science experts. Additionally, students tour the lab facility and interact with high tech lab equipment.

Natick & Haverhill, Massachusetts, USAIn partnership with the American Chemistry Society, employees host National Chemistry Week events both in the community and at the Natick facility.


Cambridge and Bromborough, UKThrough a Royal Society of Chemistry accredited outreach program, Sigma-Aldrich scientists travel to local schools to teach science lessons and hold science demonstrations.

Munich, GermanySigma-Aldrich collaborates with local universities through monetary and product donations. Additionally, Sigma-Aldrich employees guest lecture on a broad range of science topics.

Tokyo, JapanSigma-Aldrich partners with the National Museum of Emerging Science and Innovation (Miraikan) and through product and monetary donations ensures students have access to high quality lab equipment. Employees also volunteer during the annual Grand Contest on Chemistry competition.

Buchs & Zurich, SwitzerlandSigma-Aldrich collaborates with the University of Zurich and University of Bern by supporting the Chemical and Molecular program. Sigma-Aldrich hosts students at the Buchs facility, provides mentors and hosts annual research competitions.

Bangalore, IndiaEmployees travel to local schools and community events to host STEM demonstrations and to discuss what a career in science looks like. Employees also partner with local universities to guest lecture and provide facility tours.

Arklow, IrelandEmployees partner with a local primary and secondary school by supporting the schools science department. Additionally, employees regularly travel to the school to guest lecture and host science demonstrations.


SCIENTIFIC RESEARCH

Sigma-Aldrich’s mission is to enable science to improve the quality of life. Every day, our scientists enable and support researchers from around the world in trying to find life-saving cures, in making technological advancements and in improving the environment. To continue to drive innovation and breakthroughs in research, we are committed to investing more than 30% of charitable grants annually into scientific research.

To accomplish this, we work collaboratively with research and academic institutions around the world to leverage our funds, products and employees to push the needle on some of the world’s most pressing problems. By utilizing our broad range of skillsets and products, organizations are able to focus more of their time on research.

In the coming years, we will develop even stronger relationships with our partners by utilizing our R&D and Technical Service groups to identify targeted solutions to specific research problems. Our goal is to be a resource in the fight against diseases such as cancer, autism, diabetes and malaria.

In 2013, we partnered with and contributed to a number research organizations around the world including:

Autism SpeaksSigma-Aldrich partners with Autism Speaks, the world’s leading autism research and advocacy organization. Autism Speaks is dedicated to funding research into the causes, prevention, treatments and a cure for autism. Sigma-Aldrich employees from a number of Sigma-Aldrich sites also contribute by participating in Walk Now for Autism Speaks and other local events.

JDRF (formerly the Juvenile Diabetes Research Foundation)

JDRF is the largest charitable supporter of Type 1 Diabetes (T1D) research in the world and works to treat, prevent, and hopefully cure T1D. Sigma-Aldrich is committed to supporting JDRF’s mission to completely eliminate T1D through time and monetary donations.

Cancer Research UK Cancer Research UK is one of Europe’s leading cancer research organizations, funding research into more than 200 different types of cancer and promoting cancer awareness campaigns. Sigma-Aldrich employees and the Company contribute to the organization through a number of events such as charity walks, bake sales and participation in their signature event, Race for Life.

Muscular Dystrophy AssociationMuscular Dystrophy Association (MDA) is the world’s leading nonprofit health agency dedicated to finding treatments and cures for muscular dystrophy and other neuromuscular diseases. Sigma-Aldrich supports MDA through title sponsorship of their annual Muscle Bash event in St. Louis, which brings in hundreds of thousands of dollars a year for research.

St. Louis Children’s HospitalSigma-Aldrich supports the St. Louis Children’s Hospital through an endowment fund at the Children’s Discovery Institute (CDI). CDI is a world-class center for pediatric research and innovation created to encourage researchers to ask bold questions and to take bold risks to uncover answers.


SIGMA-ALDRICH FOOD DRIVE

2,335employees participated

46,699lbs. of food collected

10lbs. collected per employee

(average)

100% of production facilities and 67% of all facilities have implemented plans for local community engagement, impact assessments and development programs.

There were zero grievances related to negative impacts on society filed in 2014.

SO1, SO11

In 2012, Sigma-Aldrich employees from around the U.S. participated in the first ever U.S. wide food drive. Wanting to reach even more families in need, employees expanded the food drive internationally in 2013.

Twenty-two sites from around the world collected food and monetary donations from mid-November thru mid-December. Based on 2012’s success, a goal of 20,000 pounds was set, almost 7,000 pounds more than our 2012 goal.

Similar to 2012, Sigma-Aldrich employees came together with an outpouring of donations. After four weeks, 46,500 pounds of food was donated to community organizations around the world – more than double the original corporate goal and equivalent to almost 39,000 meals. The food drive was supported by 180 employees from across the U.S., who volunteered more than 600 hours during the four weeks. In 2014, we hope to expand the food drive to more of our sites around the world.

Site highlight: GlasgowFollowing the Sigma-Aldrich food drive, employees in Glasgow, UK, began volunteering at the City Mission Food Bank in Glasgow to sort, box and distribute food boxes. As a result of the recession, Mission Food Bank saw a sharp increase in the need for their services and utilizes a team of volunteers to ensure families receive the food and support they need.


CORPORATE GIVING & SIGMA-ALDRICH FOUNDATION

We approach charitable giving as we approach challenges in our labs – by seeking the most effective and efficient solutions. We do this by partnering with innovative programs and organizations that are working to address society’s most pressing problems.

We take time to make sure we are developing partnerships that enable us to create strong, impactful and long-term relationships. Through these partnerships we address a number of unmet or under-met needs in the communities we serve.

Corporate PhilanthropySigma-Aldrich understands that it can leverage its employees’ skills and monetary donations more effectively by partnering with organizations that are aligned with Sigma-Aldrich’s core business competencies. As a result, we partner with organizations around the world that align with one of three categories:

STEM (SCIENCE, TECHNOLOGY, ENGINEERING, AND MATH) EDUCATION

Our goal is to inspire the next generation of scientists and STEM professionals. That is why we partner with schools, community organizations, and other corporations to address the growing need for STEM proficient individuals around the world.

SCIENTIFIC RESEARCH

Sigma-Aldrich has become a leading life science and high technology company by working tirelessly to improve processes and increase quality. We use this same tenacity to fund and support research with focuses on disease, greener chemistry and other areas of interest to our overall mission – enabling science to improve the quality of life.

ECONOMIC DEVELOPMENT THROUGH SCIENCE

We understand that Sigma-Aldrich is only as strong as the communities in which we operate. We partner with non-profit organizations that spur growth in the broader science sector by incubating and supporting robust STEM ecosystems that, we believe, provide an essential benefit to local and regional financial and knowledge economies.

Sigma-Aldrich FoundationSeparate from the Sigma-Aldrich Corporation, the Sigma-Aldrich Foundation is committed to supporting civic and other community-based organizations. The Foundation supports organizations outside of the three charitable giving areas The Company focuses on and utilizes the Sigma-Aldrich Foundation Principles to guide funding decisions.

The Sigma-Aldrich Foundation supports organizations that focus on: the advancement of science, education, health and human services and other civic community organizations.

GIVING BREAKDOWN

Company Money Foundation Money Products

2010 2011 2012 2013

C $373,793 $817,989 $739,000 $887,000

F $297,000 $379,000 $312,000 $317,000

P $186,000 $873,941 $1,093,577

$856,793 $1,196,989 $1,924,941 $2,297,577

GIVING BREAKDOWN BY CATEGORY

STEM: 22% Research: 39% Civic: 39% Economic Development: 0%


Without question the primary driver of growth at Sigma-Aldrich is its employees. It’s our employees who bring new ideas, who execute them on a daily basis and who respond to our customers’ needs by delivering best in class service. We work to foster an environment that makes Sigma-Aldrich an even better place to work. That is accomplished by investing in our employees through training, tuition reimbursement, broad benefit packages, by creating a safe workplace, providing consistent performance feedback and fostering an environment that is diverse and free of discrimination.

Master glassblowers from the Sigma-Aldrich Glassware shop in Milwaukee, Wisconsin create custom glassware for scientists and labs around the world.


Equal Opportunity The Company does not discriminate against any employee, applicant, customer, supplier or other business associate on the basis of race, creed, color, religion, gender, sexual orientation, age, national origin, disability or military status. It is the Company’s intent to provide equal opportunity to all employees, applicants and business associates based on merit. The Company was not fined by the Equal Employment Opportunity Commission (EEOC) in 2013.

Across the Company, 95% of employees who utilize parental leave return to work.

Non-Harassment The Company is committed to its core beliefs, which include the treatment of all employees with respect and dignity. Accordingly, the Company does not tolerate harassment, sexual or otherwise, against any employee, applicant, customer, supplier or other business associate. Any behavior that creates an intimidating, hostile or offensive working environment is strictly prohibited.

Free AssociationThe members of our workforce represented by labor / collective bargaining agreements are primarily located in our EMEA (Europe/Middle East/Africa) region and represent approximately 4% of our total workforce in that region. Our labor agreements require one to twelve months notification for any significant operational changes depending on the country and the agreement. Additionally, 3% of employees are in formal agreements with trade unions with health and safety topics are covered.

In 2013, there were no grievances filed related to labor practices.

There were no incidents involving indigenous rights violations throughout the past five years.

There were no grievances related to human rights filed and none of our facilities have been subject to human rights reviews in the past five years.

In 2013, no acts of discrimination were substantiated.

Working AgeThe Company abides by all local employment laws related to minimum age of employment or has a country-wide minimum age requirement, whichever is higher, and does not tolerate underage child labor. As a corporate-wide policy, the Company does not employee anyone under the age of sixteen (16) except in countries that allow the employment of apprentices at a younger age. The Company abides by all local laws related to employment of apprentices and does not employ any person under the age of fourteen (14)*.

*The Company’s apprenticeship programs are for educational benefit and are consistent with Article 6 of ILO Minimum Age Convention No. 138 and/or consistent with Article 7 of ILO Minimum Age Convention No. 138.

Involuntary and Compulsory LaborThe Company ensures all employees receive at least the legally mandated minimum wage for the country of employment. Additionally, the Company ensures employees are compensated for overtime hours at the local legal rate or higher and is committed to paying employees accurately and in a timely manner. The Company does not deduct wages as a disciplinary measure.

OUR PEOPLE

G4-10, G4-11, G4-15, EC5, LA1, LA3, LA4, LA5, LA8, LA16, HR2, HR3, HR4, HR8, HR9, HR12


We strongly believe that every employee has the right to work in an environment that is respectful and free of discrimination. Sigma-Aldrich has communicated this to all employees and management. We take all employee concerns seriously and have trained our attorneys and Human Resources professionals to promptly conduct rigorous investigations to determine the veracity of discrimination claims.

Through the adherence to and annual review of the Business Code of Conduct policy and the UN Global Compact, Sigma-Aldrich ensures all aspects of the business continue to mitigate risk of human rights violations that is supported by approximately four hours of training annually for management or approximately 20% of the organization.


9,480employees

NUMBER OF EMPLOYEES & BY REGION

M F TOTAL %Americas 2,928 2,049 4,977 53%EMEA 1,595 1,480 3,075 32%APAC 938 490 1,428 15%TOTAL 5,461 4,019 9,480

CHANGE FROM 2012

2013 2012DELTA(12-13)

APAC 1,428 1,363 65EMEA 3,075 3,094 -19Americas 4,977 4,580 397TOTAL 9,480 9,037 443

JOB CREATIONM F

541 413

TURNOVER BY GENDER & AGEM F

<40 523 356>40 145 89TOTAL 672 440Percentage Rates 7% 5%

EMPLOYEES BY CONTRACT TYPEExternal Consultant 330External Contractor 364Intern 39Regular 8,747TOTAL 9,480

JOB CLASSIFICATIONManager/Supervisor 1,826Individual Contributor 7,654

G4-10


WILThe Sigma-Aldrich Women in Leadership (WIL) Network celebrated its fourth year in 2013 and continues to gain momentum. The Network membership includes more than 300 women leaders from various locations in the U.S., in addition to the active participation and support of the Sigma-Aldrich senior leadership team.

Since its inception, the WIL mission has remained the same - to create an inclusive community that connects the needs and interests of women at Sigma-Aldrich to promote personal and professional growth. The network accomplishes this by focusing on three key themes:

• Connecting Leaders

• Sharing Experiences

• Celebrating Successes

2013 was an exciting year for the WIL Network. The Network continued to connect leaders through four formal events, which featured topics such as volunteerism, understanding the basics of finance, building a professional development plan and navigating your career path. In addition, all U.S. sites held local networking sessions throughout the year with an emphasis on personal and professional development, community involvement and putting into action the insights gained from prior events.

The WIL Network reinforces the importance of taking charge of one’s own developmental growth. In 2013, the Network introduced the “WIL Passport” concept, challenging every member to accomplish something new each month, such as volunteering for a cross-functional project or seeking out a mentor. Individuals kept track of their results electronically through a website and overall progress was shared on a monthly basis. In the end, nearly 50 members participated in the “WIL Passport.”

When developing WIL programs or selecting activities, careful consideration is given to ensure that the impact ties back to one of

100% of security personnel are trained in the policies and procedures concerning aspects of human rights that are relevant to operations.

our key themes. In 2014, the Network is giving particular attention to Sigma-Aldrich’s leadership competencies and is aligning each of its quarterly, formal meetings to one of the following leadership competencies:

• Global Business Knowledge

• Command Skills

• Motivating Others

• Business Acumen

This year the WIL Network also plans to continue its emphasis on community involvement by supporting several non-profit organizations whose mission aligns with that of the Network. Another focus area for 2014 is “going global” expanding our reach to women outside the U.S.

BLN Recognizing the need for an African American employee resource group, Sigma-Aldrich launched the Black Leadership Network (BLN) as an affinity group African Americans in St. Louis in 2012. In keeping with Sigma-Aldrich’s commitment to diversity and inclusion, the mission of the BLN is to create an inclusive community that supports the personal and career development of its members. BLN’s objectives are to deliver unique and relevant opportunities for professional development, career planning and networking. The strategic priority of BLN is to develop and advance African American talent.

BLN has tailored programs and events to meet the needs and interests of its membership. The programming is designed to enhance the key leadership and professional development skills that are important to members and the Company as a whole. BLN hosts a broad range of events and workshops including a speaker series to address topics of networking and career development, informal networking events, and community events. BLN is committed to offering opportunities for professional development and growing the membership base.

DIVERSITY

HR7


EMPLOYEE DEVELOPMENT

Building Leaders At Sigma-Aldrich Our efforts to develop mission-critical skills at Sigma-Aldrich continued in 2013. Approximately 700 of our employees participated in professional development training sessions averaging 3.4 hours per employeee. Through these programs we encourage employee development at all levels of the business. We offer leadership programs beginning with the transition from individual contributor to first-time manager with more advanced offerings targeting the skills/capabilities required for the relevant stage of leadership.

Programs are presented in a “toolkit” format, which allows employees the ability to gain concise and practical training on a single topic that can be immediately applied in the workplace. Toolkit topics include:

SATISFACTION POWERThis program focuses on how to take greater accountability and ownership for your own job satisfaction.

BEHAVIORAL INTERVIEWINGThis program focuses on how to make more informed hiring decisions and to select the best candidate for open positions.

LEADING CHANGEThis program distinguishes between the hard side (project planning, hardware, and testing) and the soft side of change (leadership, communications, and teamwork) and how to bridge the gap.

COACHINGThis program focuses on how to improve day-to-day coaching skills and feedback to employees.

HIGH PERFORMANCE TEAMSThis program focuses on how to build effective teams in both a traditional and virtual environment.

Executive Development Program Sigma-Aldrich partners with Washington University in St. Louis’ Olin School of Business to offer an Executive Development Program (EDP) for high potential employees. In 2013, the two week program attended by 25 senior leaders from around the world carried the theme of “Deliver Today, Elevate Tomorrow.” It presented a broad view of strategy, execution and leadership skills, while also providing an integrated perspective on general management roles.

The program, culminated in a case challenge in which participants were partnered with colleagues from around the globe, working together to address a current business issue.

The program offered a unique educational experience and accelerated the development of the employees involved ensuring the next generation of leaders at Sigma-Aldrich is well prepared for whatever comes their way.

FUEL CampaignIn early 2013, an integrated, global, strategic communication plan was developed to stimulate employee engagement and to encourage long-term organizational commitment to the customer-centric strategy. The goal was for employees to gain a better understanding of the strategy, to increase their knowledge of our customers and to have a clear view of the importance of their role in supporting the successful execution of the strategy.

The resulting campaign was designed to resonate with employees around the world and to inspire them to understand how what they do every day supports our customers and our mission of enabling science to improve the quality of life. The heart of the campaign centered on the word “FUEL,” an acronym for:

• Focus on your customer

• Understand our strategy

• Engage to support our strategy

• Lead our success through results

The FUEL message served as the catalyst to challenge employees to focus their attention on creating solutions that benefit our customers around the globe.

Employees have responded positively to the FUEL campaign. In a recent survey, 71% of the employees who responded agree that the FUEL initiatives have helped them understand how their roles support the customer-centric strategy and improve the quality of life. FUEL and its customer-centric message will live on in 2014 and beyond as new aspects of the campaign are added and employee engagement levels increase.

LA9, LA10


HR 2013 FOCUS

Feedback Understanding employee expectations and receiving timely feedback directly from supervisors are hallmarks of effective performance management. We survey employees to measure engagement and to capture ideas on how we can continue to improve. Traditionally, companies reserve opportunities for performance feedback until year-end performance appraisals – an efficient, but not always effective way to coach employees. We utilize a performance management system for each and every Sigma-Aldrich employee with a user-friendly online performance appraisal and an individual development planning process that captures feedback and compares it to leadership competencies. Both are crucial for effective development planning. Supervisors take part in performance management training and are encouraged to engage in real-time performance reviews with their employees.

Total Rewards We recognize that employee perception of total compensation includes not only today’s paycheck, but also future advancement and earnings potential within our organization. We constantly strive to build compensation programs that better recognize the contributions of our top performers and demonstrate our confidence in their abilities to take on greater challenges. Beyond career and professional growth, we provide a wide range of benefits which include, using the U.S. system as our example:

• Paid vacation and personal time

• Medical and dental coverage for both employees and their families including domestic partners

• A voluntary vision program

• Flexible spending (includes health and childcare)

• Basic life (no-cost benefit) and AD&D

• Supplemental life

• Business travel and accident insurance

• Disability (short and long-term)

• Retirement Security Value Plan (Frozen 12/2012)

• 401(k) retirement savings plan with employer match

• Tuition reimbursement

• Relocation reimbursement

• Online career opportunities that provide security for employees and their families

• Sick days

• Voluntary AD&D coverage

• Adoption Assistance

• Maternity leave (paid and unpaid, FMLA)

• Paternity leave (unpaid)

• Bonus program

• Family education benefits

• Bike-to-work and other alternative transportation benefits

• Fitness facilities

• Bereavement leave

• Flex time and telecommuting program

• Stock options

• Employee bonus program

Similar market-based, competitive benefit programs tailored to meet the needs of employees are available in all 37 countries in which Sigma-Aldrich operates.

In the U.S., Sigma-Aldrich offers an Employee Assistance Program for professional consultations on a wide range of topics including health/wellness, child and elder care, family or parenting issues, work/life balance, marital or relationship issues, grief and loss, alcohol or chemical dependencies, legal matters and more. This program is offered to employees at no cost and is strictly confidential. It is there to support employees and members of their households in coping with concerns and any challenges they may face.

Health Initiatives Sigma-Aldrich invests in wellness programs that make a difference in the lives of our employees. Our goal is to empower and motivate our employees to manage their health. We encourage employees to obtain and understand information that is vital to their health, including their blood pressure, cholesterol, blood sugar and body mass index. In previous years, we encouraged employees to complete Personal Health Assessments and participate in diabetes screening. Additionally, all of our U.S.-based employees are eligible for full biometric screening.

These initiatives help employees to identify and address areas of risk, establish individual health and fitness goals and measure their progress. The Company provides access to online tracking tools, wellness coaches and programs that support disease prevention, weight management, stress management, tobacco cessation and overall health and fitness. In addition, the Company subsidizes 50% of the cost of participation in the Weight Watchers program. Wellness Champions at each site further engage employees by coordinating educational speakers and exercise and fitness activities. The goal is to inspire employees to achieve and maintain excellent health. Effective January 1, 2014, all Sigma-Aldrich worksites will be tobacco free.

Coverage of the organization’s defined benefit plan is 107%.

EC3, LA2, LA10, LA11


OUR CUSTOMERS

As our markets expand and global trade continues to trend upwards, the timely arrival of a globally accepted hazard communication system has helped ensure that the hazards posed by Sigma-Aldrich supplied chemicals are easily recognizable and understood by customers on any continent. GHS, or the Globally Harmonized System of Classification and Labeling of Chemicals, has provided a standardized framework for categorizing and communicating various health and physical hazards associated with a product. Sigma-Aldrich is proud to be at the industry forefront in the conversion of our Safety Data Sheets (SDS) and labels into a GHS aligned format.

To better ensure the safety of our customers, in addition to adopting GHS elements on our Safety Data Sheets and labels, we also make our SDSs available to our customers in more than 30 different languages. With more than a quarter million products having a GHS hazard classification, the large variety of translations equates to millions of SDSs being maintained and updated on a regular basis. The Sigma-Aldrich Product Safety and Labeling team continually evaluate this information to make sure our customers always receive the most up-to-date and relevant safety information available.

Our packaging group works with our Transportation Compliance team to design appropriate packaging to ensure products can be stored and transported safely. Packaging components are reviewed regularly to incorporate new findings and to ensure compliance with Department of Transportation (DOT) and global transport regulations. Our team of scientists is constantly working on developing ways to either substitute or reduce the use of hazardous substances in the manufacturing of our products through our greener chemistry initiatives.

Our Safety Data Sheets are used around the world by renowned research and government institutions for training on the new GHS elements

More than 1.5 million safety data sheets are downloaded per month

Safety Data Sheets are authored by a team of global scientists to ensure accuracy and continuity.

Sigma-Aldrich does not currently have any operations that have any negative impact on the local community. Due to our business there is potential for negative impact, however, Sigma-Aldrich works to mitigate risk through strong management practices to protect stakeholders.

Appropriate disposal information is included in product information and the SDS to ensure safe disposal of products at the end of their life cycle. Sigma-Aldrich is committed to complying with all applicable laws in all countries in which we do business. Compliance with health, safety and environmental regulations is monitored by our Environmental Health and Safety Department. Reports of possible non-compliance with food, drug and device regulations are investigated by personnel from our Quality Assurance Department with input from affected parties. Our Trade Compliance group works to ensure compliance with applicable trade regulations. Sigma-Aldrich’s commitment to maintaining compliance with laws and regulations includes a state-of-the-art system of policies and procedures backed-up by an audit program to assess compliance. Our IT systems allow us to identify materials classified as hazardous, blocking them for sale until customer qualification requirements have been reviewed and relevant hazardous material information and documentation is provided to ensure products are handled appropriately throughout the supply chain. In 2013, we had no incidents of non-compliance with regulations or codes concerning the health and safety of our products.

Sigma-Aldrich is committed to providing high quality products to all of its customers. The International Standards Organization (ISO) provides a strong quality systems framework and certification process that is recognized worldwide. The number of Sigma-Aldrich facilities that hold one or more ISO certifications is reflected in the charts on the next page.

SO2, PR1, PR3, EN2, EN28


Keeping Customers Informed SOLVING ISSUES

Our Technical and Customer and Sales Services teams communicate with thousands of external and internal customers each year. In 2013, Sigma-Aldrich’s product portfolio grew by 5,000 products. As our product portfolio continues to grow, the expectation we have of Technical and Customer and Sales Services teams grows as well. To help address our customers’ needs we’ve implemented our PDSA (Plan, Do, Study, Act) model to expedite our assistance to them so they can get back to their work faster.

Our Global Technical Service team includes approximately 150 scientists that assist in solving customers’ problems via phone, email or live chat. Our team is working to bring more information to our customers in formats that are easy to access globally at any time. Our FAQ’s and enhanced web help tools have also helped reduce call loads.

Building on the PDSA to improve processing of customer complaints, in 2013 Technical Service spread the results of this success to its general complaint process. The department also adopted a new knowledgebase platform and organizational structure. This change is designed to strengthen the execution of migrating our communication strategy from a “one-to-one” model to a “one-to-many” model that more effectively leverages the knowledge gained from our close association with customers.

In addition to our Customer and Technical Service representatives’ commitment to customer satisfaction, our eBusiness unit ensures customers ordering online have a quality experience as well. Online customers are regularly asked for their feedback and satisfaction with the ordering experience.

“I wanted to pass this along as a stellar example of how your employee solves problems and makes our lives better. While she was not allowed in the system to enter the quote for me, she did not stop there; she took it to the next level and created a template for me so that it only required 1/10th of the time on my part.

This is exactly the type of value addition that we cherish in the field. She consistently moves the ball forward for us and is directly responsible in many ways for real sales increases.

Thanks again for your team’s support.”

– Customer Feedback

PRECAUTIONARY PRINCIPLE

Sigma-Aldrich utilizes the precautionary principle by informing employees and customers of its products and potential hazards. Sigma-Aldrich does not restrict the purchase of products that have potential hazard, however, due to the regulated nature and potential hazards of our products clear information regarding safety and handling are provided to those who work with or purchase these products. Sigma-Aldrich actively works through its Green Chemistry program to find alternative solutions where feasible to reduce hazards.

ISO CERTIFICATIONS

ISO 14000 cGMP & ISO 9000

QUALITY COMPLAINTSper 1,000 lines shipped

SERVICE COMPLAINTSper 1,000 lines shipped

CUSTOMER OBSERVATIONS PER AUDIT

G4-14, PR5


COMPLIANCE

Product Safety The Trade, Product and Screening Compliance teams continue to develop best-in-class cross-border and regulatory programs which ensure compliance, improve cycle time and reduce costs, while giving our customers peace of mind that products will arrive in a safe and compliant manner.

In 2013, the Trade Compliance team launched a Free Trade Agreement initiative focused on reducing customs duties by leveraging bilateral cross-border agreements such as the North American Free Trade Agreement (NAFTA) and the U.S.-Korea Free Trade Agreement (KORUS). These agreements allow Sigma-Aldrich to reduce or eliminate duties on qualifying products moving between parties to the agreements. In 2013 alone, the Trade Compliance team achieved a $1.2 million reduction in duty spend by utilizing these agreements. Going forward, the team plans to conduct a comprehensive analysis of the Sigma-Aldrich global supply chain with the purpose of identifying additional applicable trade agreements and duty reduction opportunities. Also in 2013, members of the team focused their efforts on the SAP Next systems implementation. This project, led by the IT department, will substantially shape our future business processes and offer significant compliance improvements, including the ability to harmonize trade, regulatory and screening processes globally.

As part of the harmonization efforts, the U.S. and EMEA Product Compliance staff worked with members of the Global Shared Services (GSS) compliance staff in Bangalore to identify opportunities for consolidating activities. This consolidation resulted not only in the reduction of cycle time for new product regulatory reviews, but also allows us to extend value-add services to our customers, such as Third Party Procurement and Importer of Record Services.

The Screening team continues to improve its efforts to ensure Sigma-Aldrich products are used in legitimate scientific purposes and by appropriate end users. In 2013, the Screening team implemented several automated processes to increase the speed and accuracy of obtaining end user information from our customers, ensuring that Sigma-Aldrich products reach our approved customers as quickly as possible.

The Product Compliance Team is responsible for reviewing our products for regulatory controls and requirements and ensuring our screening systems are set up to appropriately screen orders for license and permit requirements. Product Compliance has been working with the Bioinformatics group to develop a Structure Based Compliance Tool (SBCT) that will allow the staff to review products more quickly and to determine regulatory aspects at a higher degree of accuracy than ever before. We are excited about this tool and the team continues to develop and refine the SBCT so it can eventually be used by compliance teams globally.

No significant fines for non-compliance with laws and regulations concerning the provision and use of products and services.

No incidents of non-compliance with regulations and voluntary codes concerning product and service information and labeling.

Sigma-Aldrich sells some products which are not allowed in certain countries based on decisions by legislative bodies. Sigma-Aldrich adheres to these regulations and does not knowingly sell such products into these countries.

Sigma-Aldrich does not sell products directly to end users. Our products are specifically meant for use by researchers in laboratories and by other validated manufacturers.

SO8, PR4, PR9, PR6


SAFETY

Safety and Environmental Regulations Safety is an integral part of Sigma-Aldrich’s belief system. The Company is committed to providing a safe working environment for all employees and is proud of its record with respect to safety. Accordingly, employees are expected to perform their work safely, in compliance with all applicable occupational health and safety regulations, as well as governmental and industry standards for protection of the environment. Every manager in the Company uses safety targets as part of their bonus compensation. Company policies and practices have been established to provide guidance in these areas and should be strictly followed. In 2013, there were:

• No fines, sanctions, or grievances for non-compliance with environmental laws and regulations.

• No significant* fines for environmental impact from transportation and other goods and materials used in our operations.

• No significant spills of hazardous waste.

• No transport, importation or treatment of hazardous waste.

• No significant fines for non-compliance with laws or regulations considering the provision and use of our products.

• No incidents of non-compliance with regulations or voluntary codes concerning the health and safety impacts of our products and services during their life cycle.

Sigma-Aldrich spent more than $2.3 million in environmental protection, management and other related EHS programs.

Also in 2013, Sigma-Aldrich had no fatalities at its sites, no occupational disease occurrences and an RIR of .85, SIR of .23 and MIR of 4.05.

12safety audits and two Transportation

Safety and Compliance (DG) audits were conducted at

Sigma-Aldrich facilities in 2013.

Each year the Global Environmental Health and Safety Department outlines a comprehensive set of goals to improve the safety of our employees. There is a continued emphasis on maintaining a preventative culture through comprehensive safety training rather than a reactive one. To aid in the creation of that culture, we once again met or were below our RIR, SIR and MIR goal.

We support the employee based near miss reporting with risk assessments for manufacturing, packaging and distribution areas at all of our sites. We continue to identify risks in these key areas before injuries or incidents occur, taking proactive steps to eliminate and manage those risks. Another proactive step we take is our Corporate EH&S Audit program, which reviews site conformance with regulatory requirements and our Corporate EH&S Principles that go beyond general compliance. The in-depth audits review site practices, procedures, training and document retention. Our large sites are audited every three years with the tier two sites being audited every five years. We also work to integrate new acquisitions into our proactive safety management culture with an EH&S audit within three months of acquisition. Finally, Sigma-Aldrich implemented a Transportation Safety and Compliance (DG) audit program in 2013 to ensure our internal transportation system is monitored for safety concerns.

Sigma-Aldrich consistently has a leading safety record within industry. Each year our goal is zero incidents, however, due to the nature of our work it is not always possible to mitigate every incident. In 2013, our goal was to reduce recordable and minor injuries by 10%. Though our overall injury rate increased in 2013, this number reflects injury rates of newly acquired entities. We will continue to work toward these goals by implementing site safety improvement plans focused on historical injury cause and identifying preventative measures, risk assessments and safety management systems.


RECORDABLE INJURY RATE (RIR)

Number of injuries

Sigma-Aldrich RIR Industry Average

SERIOUS INJURY RATE (SIR)

Serious injury = three or more days lost work

*Significant is defined as more than $50,000

+ Reflects changes due to majors acquisitions LA6, EN24, EN25, EN29, EN31, EN34, PR2


What if transparency was the standard operating practice of every company?Strong governance is paramount in today’s business environment. Sigma-Aldrich works pro actively to engage employees in understanding their role in fiscal accountability for our entire organization. Employees and shareholders can share recommendations or direction regarding Global Citizenship at the annual shareholders meeting that is held in St. Louis on the first Tuesday of May each year. Alternatively, contact can be made through the Sigma-Aldrich website at http://investor.sigmaaldrich.com/contactBoard.cfm to provide recommendations and feedback.

Sigma-Aldrich employees are made aware of these opportunities annually through letters, emails and intranet postings. There were no critical items related to economic, environmental or fiscal performance raised through these channels.

All information regarding compensation, conflict of interest, board qualifications and board performance can be found at http://investor.sigmaaldrich.com/governance.cfm and http://investor.sigmaaldrich.com/annuals.cfm.

Sigma-Aldrich Global Citizenship performance is reviewed by the entire board annually and is specifically reported directly to the Audit committee.

http://investor.sigmaaldrich.com/committees.cfm

FISCAL ACCOUNTABILITY

G4-34, G4-35, G4-40, G4-41, G4-42, G4-43, G4-44, G4-45, G4-46, G4-47, G4-49, G4-50, G4-51, G4-52, G4-53

http://investor.sigmaaldrich.com/contactBoard.cfm

http://investor.sigmaaldrich.com/governance.cfm and http://investor.sigmaaldrich.com/annuals.cfm.



http://investor.sigmaaldrich.com/committees.cfm


BOARD MEMBERS

Rakesh Sachdev+ President and CEO

Rebecca M. Bergman*+ Vice President for Science and Technology, Medtronic Inc.

George M. Church* Professor of Genetics at the Harvard Medical School and Director of the Center for Computational Genetics in Cambridge, Massachusetts

Michael L. Marberry* President and CEO J.M. Huber Corporation

W. Lee McCollum* Former Executive Vice President and Chief Financial Officer, S.C. Johnson & Son, Inc.

Avi Nash*+ Founder of Avi Nash LLC (Former partner of Goldman Sachs)

Steven Paul* Director, Appel Alzheimer’s Disease Research Institute and Professor of Neurology, Psychiatry an Pharmacology, Weill Medical College of Cornell University

J. Pedro Reinhard*+ President of Reinhard & Associates (Former CFO, Dow Chemical Company)

D. Dean Spatz*+ Former Chairman and CEO, Osmonics, Inc.

Barrett Toan* Chairman of the Board, Former Chairman and CEO of Express Scripts, Inc.

*Sigma-Aldrich board members considered to be independent.

+Sigma-Aldrich board members considered to be diverse

GLOBAL CITIZENSHIP MANAGEMENT STRUCTURE

BOARD COMPOSITION AGES MALE FEMALE50-59 3 (30%) 1 (10%)60-69 6 (60%)

10%of the Board is made up of females

(1 female, 9 males).

50%of the Board is made up

of minority groups.

Board of Directors

Executive Team

Global Citizenship Team

Environmental Sustainability Social Responsibility Fiscal Accountability

LA12, G4-36, G4-38, G4-39


FISCAL ACCOUNTABILITY & GOVERNANCE

Our mission at Sigma-Aldrich is enabling science to improve the quality of life. We strive to be the trusted global partner-of-choice for our customers by building on our proven foundation of trust, service and innovation. The only sustainable way to achieve this goal is by providing a high standard of behavior, along with unquestioned integrity. Continued honest and ethical business conduct is a cornerstone of our “One Company” values. Constant respect for people means we treat every individual we interact with around the world with the utmost dignity. Maintaining our corporate integrity is the responsibility of each of us. As Sigma-Aldrich employees, we are all expected to uphold this dedication to corporate ethics on a daily basis.

Tell The Truth Our commitment to ethics in business includes a special emphasis on candor. We must be truthful in all communications with one another, customers and governmental agencies. We must keep complete and accurate business records. Only by being honest and forthcoming will our Company merit the respect and trust it needs to carry on its business operations successfully.

Compliance and Ethics UNDERSTAND AND COMPLY WITH ALL LAWS AND REGULATORY REQUIREMENTS

Employees are expected to conduct business in compliance with all laws, rules and regulations of the countries in which they conduct business on behalf of the Company. These laws and regulations include those related to antitrust and competition, boycotts, accounting and financial reporting standards, import and export regulation, foreign currencies, sales and Value Added Taxes, income taxes, employment, safety, the environment, food and drug regulation and insider trading laws. A single violation by even

one employee can cause great harm to our Company’s reputation and our ability to carry on operations as well as compromising the work of many others.

Additionally, law enforcement agencies are increasingly enforcing laws by prosecuting not only corporations, but also their employees, seeking to subject them to heavy penalties, fines and jail terms. Every employee is expected to be familiar with the basic legal requirements that apply to his or her duties on the job. For example, sales representatives and marketing managers are expected to know basic rules regulating marketing practices and antitrust principles, such as the prohibition against price fixing and the rules governing restrictions on dealers and distributors. Production managers are expected to know the environmental and safety rules that apply to their manufacturing operations. Human Resources specialists and all managers who make hiring, compensation, promotion, termination and other decisions affecting employees should be familiar with applicable equal employment opportunity laws, other employment laws and the Company’s human resources policies. Indeed, even though it is not always apparent, nearly all of us require some degree of familiarity with laws that affect our business. Should a conflict arise between the laws of countries in which we operate, or between any Company policy or directive and any law or regulation, the conflict is immediately reported to the General Counsel. Conflicts related to safety or compliance are immediately reported to the Vice President of Environmental Health and Safety and Compliance. It is not the Company’s intent to issue any policy or directive that could violate any law or regulation. Whenever we have any doubt about our legal obligations or the appropriateness of our conduct in any situation in which we may find ourselves, we are expected to ask our supervisor or the Legal Department for instruction or advice. Sigma-Aldrich had no incidents of antitrust, anti-competitive or monopoly

Sigma-Aldrich had no incidents of antitrust, anti-competitive, corruption or monopoly practices in 2013. Sigma-Aldrich analyzes all of its business units (Research, Applied and SAFC) for risks related to corruption. 100% of our business units are analyzed for risk related to corruption and are prioritized by geographic location using risk based approach.

G4-16, SO3, SO5, SO7


practices in 2013. Sigma-Aldrich analyzes all of our business units (Research, Applied and SAFC Commercial) for risks related to corruption. 100% of our business units are analyzed for risk related to corruption and are prioritized by geographic location.

Sigma-Aldrich belongs to professional organizations such as National Associations of Manufacturers, SOCMA and American Chemistry Society that communicate issues, collect member comments, and submit on the behalf of the membership. We do not have a topic of focus with these organizations and are not actively involved in having them lobby on our behalf. Sigma-Aldrich does not directly lobby at the State or Federal level nor does it have a dedicated government affairs organization.

Financial Reporting Compliance ACCOUNTING SYSTEMS AND RECORDS

The books and records of the Company’s operations must be maintained in accordance with U.S. Generally Accepted Accounting Principles (GAAP) as interpreted by the Company’s Controller. For non-U.S. locations, statutory books and records must be maintained in compliance with local statutory accounting regulations, while monthly financial reporting to Corporate must comply with U.S. GAAP. The accounting systems and records of the Company must fully and accurately reflect all business activities of the Company to serve as a basis for management of the business and to facilitate meeting the Company’s obligations to its shareholders, employees, customers and suppliers. Employees are prohibited from recording any false or misleading statements or entries, and entries that do not comply with U.S. GAAP or local statutory requirements, as appropriate, in the books and records of the Company. These records include, but are not limited to, accounting ledgers, financial statements, expense

reports, time reports, invoices, and supporting documents, both hardcopy and electronic. Employees must not incur expenses on behalf of the Company for any unauthorized or illegal purpose. Employees shall not approve or participate in any transaction or payment with the knowledge that any part of such payment is to be used for any purpose other than that described by the documents supporting the payment. Secret or unrecorded funds or assets may not be maintained by any employee for any purpose. It is expected that all expense reports and other data concerning expenditures submitted by employees will be factual, accurate and in compliance with Company policy. Dishonesty regarding any amount is considered grounds for termination.

Business Conduct Policy (BCP)In support of our commitment to the conduct of business in an ethical, safe and respectful manner, a series of in-depth training modules were developed for all of our employees. Employees averaged five hours of training on topics in safe operations, business conduct and harassment. Our security personnel were also included in separate training sessions regarding topics such as safety and human rights. 100% of our security team is trained on human rights, including any third party security personnel. Our management team is required to do annual training on corruption and our Business Conduct Policy. This training is meant to remind our management team of the responsibility they have to set an example for their employees and the importance of safeguarding our business by operating with a focus on compliance with the policy.

As part of our BCP, Sigma-Aldrich does not contribute to any political party or candidate. Sigma-Aldrich does not directly involve itself in public policy development or lobbying.

In 2013, Sigma-Aldrich did not spend any money with Public Policy/Government Affairs groups to help the US government better understand our business and how government actions can sometimes have the unintended consequence of hindering scientific research and development.

Sigma-Aldrich received no significant financial assistance from the government in 2013.*

*Significant is defined as more than $50,000 EC4, SO4, SO5, SO6, G4-56, G4-57, G4-58


Animal PolicyBioReliance provides specialized toxicology (Genetic Toxicology) and Biologics Safety Testing services to the pharmaceutical, biotechnology, life sciences and other industries. These services are provided from facilities in the US and UK. Studies including mice, rats, rabbits, guinea pigs and hamsters are performed, where appropriate, in order to supply our clients with services that meet international regulatory requirements and guidelines for the testing and manufacturing of their products. Throughout its business, BioReliance adheres to the highest standards of humane, responsible animal care. The company is in full compliance with all NIH Office of Laboratory Animal Welfare policies (US), all criteria outlined by the US Public Health Service’s (PHS) “Policy on Humane Care and Use of Laboratory Animals” and is licensed in accordance with the UK Home Office Animals (Scientific Procedures) Act 1986 (ASPA) after transposition of European Directive 2010/63/EU. BioReliance also complies with the requirements of the US Animal Welfare Act (AWA) which is administered by the US Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS).

Finally, BioReliance actively implements the practice of “The 3 R’s” - Reduce, Refine and Replace – and encourages the adoption of these principles by our clients. BioReliance is fully accredited by AAALAC International (Association for Assessment and Accreditation of Laboratory Animal Care). The use of animals is monitored by our Institutional Animal Care and Use Committee which evaluates all proposed protocols for compliance to global animal welfare regulations.

Risk StatementsSigma-Aldrich risk statements that could be affected by climate change related issues or legislation related to sustainability:

Due to heavy reliance on manufacturing and related operations to produce, package and distribute the products we sell, our business could be adversely affected by disruptions of these operations.

We rely upon our manufacturing operations to produce products accounting for approximately 60 percent of our sales. Our quality control, packaging and distribution operations support all of our sales. Any significant disruption of those operations for any reason, such as labor unrest, power interruptions, fire or other events beyond our control, could adversely affect our sales and customer relationships and therefore adversely affect our business. While insurance coverage may reimburse us, in whole or in part, for profits lost from such disruptions, our ability to provide these products in the longer term may affect our sales growth expectations and results. We have limited redundancies and back-up in our global distribution network. Our global distribution, including for our U.S. customers, is handled primarily by automated warehouses in Milwaukee, Wisconsin and Schnelldorf, Germany. The efficiency and effectiveness of our global distribution network would be significantly compromised if these warehouses were impacted by natural disasters or other local disruption. If a disruption occurs, we may not be able to secure alternate distribution and replace the compromised inventory in a timely manner, causing deterioration in our current service levels. Failure to do so could have a material adverse effect on our business and results of operations.

EC2, G4-2


We are subject to regulation by various federal, state, local and foreign agencies that require us to comply with a wide variety of regulations, including those regarding the manufacture and distribution of products and environmental matters.

Some of our operations are subject to regulation by various U.S. federal agencies and similar state and international agencies, including the DOC, FDA, DOT, USDA and other comparable U.S., state, local and foreign governmental agencies. These regulations govern a wide variety of product activities, from design and development to labeling, manufacturing, handling, sales, distribution, importing and exporting of products. If we fail to comply with any or all of these regulations, we may be subject to fines or penalties, have to recall products and/or cease their manufacture and distribution, which would increase our costs and reduce our sales. In addition to the foregoing, we have agreements in place for the sale of our products to government entities; consequently, we are subject to various statutes and regulations that apply to companies doing business with the government. A failure to comply with these statutes and regulations could result in suspension of these contracts, criminal, civil and administrative penalties or debarment.

We may be exposed to certain regulatory and financial risks related to climate change.

Our manufacturing processes for certain products involve the use of chemical and other substances that are regulated under various international, federal, state and local laws governing the environment. In the event that any future climate change legislation would require that stricter standards be imposed by domestic or international environmental regulatory authorities with respect to the use and/or levels of possible emissions from such chemicals and/or other substances, we may be required to make certain changes and adaptations to our manufacturing processes. There can be no assurance that any such changes would not have a material effect on our financial condition. Another potential effect of climate change is an increase in the severity of global weather conditions. Although we believe that we have an adequate disaster recovery plan in place, severe weather conditions, including earthquakes, hurricanes, tornadoes and/or tsunami, could potentially cause significant damage to our manufacturing facilities in locations such as California, Taiwan or St. Louis. There can be no assurance that the effects of such damage and the resultant disruption of manufacturing operations would not have a materially adverse impact to our financial results.

We are subject to regulations that govern the handling of hazardous substances.

We are subject to various federal, state, local and international laws and regulations that govern the handling, transportation, manufacture, use, storage, disposal and sale of substances that are or could be classified as toxic or hazardous substances. Some risk of environmental and property damage and environmental liabilities, including potential cleanup liability relating to currently or formerly owned or operated sites or third party disposal sites and liabilities relating to the exposure to hazardous substances, is inherent in our operations and the products we manufacture, sell or distribute. Any failure by us to comply with the applicable government regulations could also result in product recalls or impositions of fines and restrictions on our ability to carry on with or expand a portion or possibly all of our operations. If we fail to comply with any or all of these regulations, we may be subject to fines or penalties, have to recall products and/or cease their manufacture and distribution, which would increase our costs and reduce our sales.

If we fail to maintain adequate quality standards for our products and services, our business may be adversely affected and our reputation harmed.

Our life science and high technology customers are often subject to rigorous quality standards to obtain and maintain regulatory approval of their products and the manufacturing processes that generate them. A failure to maintain, or in some instances upgrade, our quality standards to meet our customers’ needs could result in the loss of a customer’s regulatory license and potentially substantial sales losses to us.


Looking Forward Looking to 2014, we are confident in our ability to deliver solid earnings growth. We are cautiously optimistic about the end market trends, helped partly by a more stable funding environment for U.S. academic and government institutions as the year progresses. Our three business units are executing on their initiatives to deliver growth, and our newly-formed Global Supply Chain team has a number of programs in place designed to improve our operational efficiency.

Our industry continues to consolidate and this trend is likely to continue for the foreseeable future. Strong companies in our space will benefit from this changing landscape, and we believe that we are well positioned to benefit from these opportunities. More and more, we are finding that our scientific breadth and depth, combined with our great products and longstanding relationships with more than a million customers, are producing opportunities to create and deliver new solutions to tomorrow’s problems.


Sigma-Aldrich requests external verification for our annual Global Citizenship Report to ensure that we’re reporting according to best practice and to provide another level of assurance to our stakeholders.

G4-32, G4-33

3RD PARTY GRI IN ACCORDANCE CORE VERIFICATION STATEMENT

INTRODUCTION

Sigma-Aldrich’s Global Citizenship Report 2013 (the Report) has been prepared by the management of Sigma-Aldrich Corporation, who retain responsibility for its content. ENVIRON’s responsibility is to carry out a limited assurance1 engagement on the Report.

This limited assurance verification was performed in accordance with the Global Reporting Initiative (GRI) standards; specifically the principles of Materiality, Stakeholder Inclusiveness, Sustainability Context and Completeness as set out in the GRI Sustainability Reporting Guidelines (Version 4.0).

VERIFICATION SCOPE AND LIMITATIONS

The limited assurance review was carried out on Sigma-Aldrich’s 2013 Global Citizenship Report content and supporting documents as presented in the GRI content index. The scope of our work was limited to a risked-based sample approach to identify likely risks of potential errors and omissions, which includes a review of the quality of content (documentation of approach to Sigma-Aldrich used to define report content and the basis of information presented). The main objectives of this review were to evaluate if Sigma-Aldrich has satisfactorily applied the GRI Reporting Framework, met the report content requirements as specified by G4 – ‘In accordance – Core’, and fulfilled the spirit of Principles concerning Report Content, Report Quality, and Boundary Setting.

TYPE OF ASSURANCE

This assurance is a limited assurance, which also follows Type 2 Principals and Moderate Level of Assurance Engagement.

DECLARATION

As an independent consultancy, ENVIRON have no financial dependencies on Sigma Aldrich Corporation beyond the scope of this arrangement. (During 2013/14, whilst ENVIRON has worked with Sigma-Aldrich on other consulting projects, ENVIRON operates strict conflict of interest checks and has confirmed independence to Sigma-Aldrich for delivering this assurance). The assurance has been carried out by a team with skills and depth of experience that provides a high level of competency for this assurance engagement.

WORK PERFORMED

This limited assurance review was carried out on Sigma-Aldrich’s 2013 Global Citizenship Report to evaluate whether Sigma-Aldrich has satisfactorily applied the GRI Reporting Framework, met the report content requirements as specified by G4 – Core accordance, and fulfilled the spirit of Principles concerning Report Content, and Report Quality. In this limited assurance, we performed the following procedures:

• Conducted a Materiality Matters Check to confirm the GRI Content Index met the requirements in providing reference to General Standard Disclosures, indication of external assurance and a navigation check;

PREPARED FOR:

Company Name Sigma-Aldrich, Inc.Company Address 3050 Spruce Street, St. Louis, MO 63103Company Contact Jeffrey Whitford, Manager, Global Citizenship

• Performed an initial review of Sigma-Aldrich’s 2013 Global Citizenship Report content and documentation of the approach used to define report content, and the basis for information presented. We conducted this initial review to identify likely risks of potential errors, omissions, or misinterpretations;

• Developed a questionnaire to collect information on how Sigma-Aldrich determined report content and the basis for each General Standard Disclosure and Specific Standard Disclosures;

• Performed a review of Sigma-Aldrich’s responses to the questionnaire in order to compare Sigma-Aldrich’s approach with GRI requirements as detailed in the GRI G4 Guidelines;

• Conducted a site visit and conducted interviews of relevant staff to evaluate Sigma-Aldrich’s data collection processes and operations at the facility level; and

• Performed a final review of Sigma-Aldrich’s Global Citizenship report to determine if meets G4 key criteria of materiality, stakeholder inclusiveness, sustainability context, and completeness.

CONCLUSIONS

ENVIRON considers that the Sigma-Aldrich Global Citizenship Report 2013 was prepared according to the requirements of, and guidelines given in, the Global Reporting Initiative Sustainability Reporting Guidelines (version 4.0).Based upon the process applied and described in this Statement, there is no evidence that the Sigma-Aldrich Global Citizenship Report 2013:

• Is not materially correct and is not a fair representation of sustainability information, and

• Has not been prepared ‘In accordance’ with the requirements defined by ‘Core’ requirements of the GRI Sustainability Reporting Guidelines (version 4.0).

CONTACTS

For further information on sustainability at Sigma-Aldrich as well as questions regarding the Global Citizenship Report and its contents, please contact Jeffrey Whitford at [email protected].

VERIFIERS:

Rob HarshENVIRON International Corporation1560 Broadway St., Suite 1905Denver, CO 80202Phone: (303) 382-5470Email: [email protected]

Completed: July 16, 2014Rob Harsh, Manager, ENVIRON International Corporation

1 Limited Assurance is based on a sampling approach as opposed to comprehensive review of all relevant documents


PERFORMANCE INDICATOR DESCRIPTION REPORTED

EXTERNAL ASSURANCE OMISSION PAGE

1. STRATEGY AND ANALYSIS

G4-1 Statement from the most senior decision-maker of the organization Yes 4

G4-2 Description of key impacts, risks, and opportunities Yes 6, 62

2. ORGANIZATIONAL PROFILE

G4-3 Name of the organization Yes 8

G4-4 Primary brands, products, and services Yes 8

G4-5 Location of the organization’s headquarters Yes 8

G4-6 Number of countries where the organization operates Yes 8

G4-7 Nature of ownership and legal form Yes 8

G4-8 Markets served Yes 8

G4-9 Scale of the organization Yes 7,8

G4-10 Total number of employees by employment contract and gender Yes 50

G4-11 Percentage of total employees covered by collective bargaining agreements Yes 48

G4-12 The organization’s supply chain Yes 23

G4-13Any significant changes during the reporting period regarding the organization’s size, structure, ownership, or its supply chain

Yes 8

G4-14Whether and how the precautionary approach or principle is addressed by the organization

Yes 55

G4-15Externally developed economic, environmental and social charters, principles, or other initiatives to which the organization subscribes or which it endorses

Yes 25

G4-16Memberships of associations (such as industry associations) and national or international advocacy organizations in which the organization

Yes 60

3. IDENTIFIED MATERIAL ASPECTS AND BOUNDARIES

G4-17All entities included in the organization’s consolidated financial statements or equivalent documents

Yes 8

G4-18 Process for defining the report content and the Aspect Boundaries Yes 8

G4-19 All the material Aspects identified in the process for defining report content Yes 10

G4-20 Aspect Boundary within the organization Yes 10

G4-21 Aspect Boundary outside the organization Yes 10

G4-22Effect of any restatements of information provided in previous reports, and the reasons for such restatements

Yes 8

G4-23Significant changes from previous reporting periods in the Scope and Aspect Boundaries

Yes 8

4. STAKEHOLDER ENGAGEMENT

G4-24 List of stakeholder groups engaged by the organization Yes 8

G4-25 Basis for identification and selection of stakeholders with whom to engage Yes 8

G4-26 The organization’s approach to stakeholder engagement Yes 8

G4-27Key topics and concerns that have been raised through stakeholder engagement

Yes 8

5. REPORT PROFILE

G4-28 Reporting period (such as fiscal or calendar year) for information provided Yes 8

G4-29 Date of most recent previous report (if any) Yes 8

G4-30 Reporting cycle (such as annual, biennial) Yes 8

G4-31 Provide the contact point for questions regarding the report or its contents Yes 8

G4-32 The ‘in accordance’ option the organization has chosen Yes 65

G4-33The organization’s policy and current practice with regard to seeking external assurance for the report

Yes 65




6. GOVERNANCE

GOVERNANCE STRUCTURE AND COMPOSITION

G4-34Governance structure of the organization, including committees of the highest governance body. Identify any committees responsible for decision-making on economic, environmental and social impacts

Yes 58

G4-35Process for delegating authority for economic, environmental and social topics from the highest governance body to senior executives and other employees

Yes 58

G4-36Whether the organization has appointed an executive-level position or positions with responsibility for economic, environmental and social topics, and whether post holders report directly to the highest governance body

Yes 59

G4-37Processes for consultation between stakeholders and the highest governance body on economic, environmental and social topics

Yes 8

G4-38 Composition of the highest governance body and its committees Yes 59

G4-39 Whether the Chair of the highest governance body is also an executive officer Yes 59

G4-40Nomination and selection processes for the highest governance body and its committees, and the criteria used for nominating and selecting highest governance body members

Yes 58

G4-41Processes for the highest governance body to ensure conflicts of interest are avoided and managed

Yes 58

HIGHEST GOVERNANCE BODY’S ROLE IN SETTING PURPOSE, VALUES, AND STRATEGY

G4-42

Highest governance body’s and senior executives’ roles in the development, approval, and updating of the organization’s purpose, value or mission statements, strategies, policies, and goals related to economic, environmental and social impacts

Yes 58

HIGHEST GOVERNANCE BODY’S COMPETENCIES AND PERFORMANCE EVALUATION

G4-43Report the measures taken to develop and enhance the highest governance body’s collective knowledge of economic, environmental and social topics

Yes 58

G4-44Processes for evaluation of the highest governance body’s performance with respect to governance of economic, environmental and social topics

Yes 58

HIGHEST GOVERNANCE BODY’S ROLE IN RISK MANAGEMENT

G4-45Highest governance body’s role in the identification and management of economic, environmental and social impacts, risks, and opportunities

Yes 58

G4-46Highest governance body’s role in reviewing the effectiveness of the organization’s risk management processes for economic, environmental and social topics

Yes 8, 58

G4-47Frequency of the highest governance body’s review of economic, environmental and social impacts, risks, and opportunities

Yes 58

HIGHEST GOVERNANCE BODY’S ROLE IN SUSTAINABILITY REPORTING

G4-48Highest committee or position that formally reviews and approves the organization’s sustainability report and ensures that all material Aspects are covered

Yes 9

HIGHEST GOVERNANCE BODY’S ROLE IN EVALUATING ECONOMIC, ENVIRONMENTAL AND SOCIAL PERFORMANCE

G4-49 Process for communicating critical concerns to the highest governance body Yes 58

G4-50Nature and total number of critical concerns that were communicated to the highest governance body and the mechanism(s) used to address and resolve them

Yes 58




REMUNERATION AND INCENTIVES

G4-51Remuneration policies for the highest governance body and senior executives

Yes 58

G4-52 Process for determining remuneration Yes 58

G4-53How stakeholders’ views are sought and taken into account regarding remuneration

Yes 58

G4-54

Ratio of the annual total compensation for the organization’s highest-paid individual in each country of significant operations to the median annual total compensation for all employees (excluding the highest-paid individual) in the same country

No

Sigma-Aldrich considers compensations of its employees to be an

internal matter.

G4-55

Ratio of percentage increase in annual total compensation for the organization’s highest-paid individual in each country of significant operations to the median percentage increase in annual total compensation for all employees (excluding the highest-paid individual) in the same country.

No

Sigma-Aldrich considers compensations of its employees to be an

internal matter.

ETHICS AND INTEGRITY

G4-56The organization’s values, principles, standards and norms of behavior such as codes of conduct and codes of ethics

Yes 61

G4-57Internal and external mechanisms for seeking advice on ethical and lawful behavior, and matters related to organizational integrity

Yes 61

G4-58Internal and external mechanisms for reporting concerns about unethical or unlawful behavior, and matters related to organizational integrity

Yes 61

7. SPECIFIC STANDARD DISCLOSURES

INDICATORS

DISCLOSURE OF MANAGEMENT APPROACH

G4 DMA Management approach to materiality Yes 9

ECONOMIC

ECONOMIC PERFORMANCE

G4-EC1 Direct economic value generated and distributed Yes 7

G4-EC2Financial implications and other risks and opportunities for the organization’s activities due to climate change

Yes 53, 62

G4-EC3 Coverage of the organization’s defined benefit plan obligations Yes 53

G4-EC4 Financial assistance received from government Yes 61

MARKET PRESENCE

G4-EC5Ratios of standard entry level wage by gender compared to local minimum wage at significant locations of operation

Yes 48

G4-EC6Proportion of senior management hired from the local community at significant locations of operation

NoAs a global corporation, this is not relevant to our

business.

INDIRECT ECONOMIC IMPACTS

G4-EC7Development and impact of infrastructure investments and services supported

NoNot relevant to Sigma-Aldrich

G4-EC8 Significant indirect economic impacts, including the extent of impacts NoNot relevant to Sigma-Aldrich

PROCUREMENT PRACTICES

G4-EC9 Proportion of spending on local suppliers at significant locations of operation Yes 25

ENVIRONMENTAL

MATERIALS

G4-EN1 Materials used by weight or volume No

This data is not currently available due to the

breadth of our product mix which is greater

than 270,000 individual products.

G4-EN2 Percentage of materials used that are recycled input materials Yes 13, 54




ENERGY

G4-EN3 Energy consumption within the organization Yes 21

G4-EN4 Energy consumption outside of the organization NoNot relevant to Sigma-Aldrich

G4-EN5 Energy intensity Yes 20

G4-EN6 Reduction of energy consumption Yes 21

G4-EN7 Reductions in energy requirements of products and services Yes 31

WATER

G4-EN8 Total water withdrawal by source Yes 18, 21

G4-EN9 Water sources significantly affected by withdrawal of water Yes 19

G4-EN10 Percentage and total volume of water recycled and reused No

This data is not currently available. Sigma-Aldrich is working to address this but does not think that

reporting will begin in the next year.

BIODIVERSITY

G4-EN11Operational sites owned, leased, managed in, or adjacent to, protected areas and areas of high biodiversity value outside protected areas

Yes 19

G4-EN12Description of significant impacts of activities, products, and services on biodiversity in protected areas and areas of high biodiversity value outside protected areas

Yes 19

G4-EN13 Habitats protected or restored Yes 19

G4-EN14Total number of iucn red list species and national conservation list species with habitats in areas affected by operations, by level of extinction risk

No

Sigma-Aldrich has minimal direct biodiversity impact and at this time we do not

feel this is material.

EMISSIONS

G4-EN15 Direct greenhouse gas (ghg) emissions (scope 1) Yes 15

G4-EN16 Energy indirect greenhouse gas (ghg) emissions (scope 2) Yes 15

G4-EN17 Other indirect greenhouse gas (ghg) emissions (scope 3) Yes 16

G4-EN18 Greenhouse gas (ghg) emissions intensity Yes 15

G4-EN19 Reduction of greenhouse gas (ghg) emissions Yes 21

G4-EN20 Emissions of ozone-depleting substances (ods) No Data not available.

G4-EN21 NOX, SOX, and other significant air emissions Yes 16

EFFLUENTS AND WASTE

G4-EN22 Total water discharge by quality and destination No Data not available.

G4-EN23 Total weight of waste by type and disposal methodi Yes 13

G4-EN24 Total number and volume of significant spills Yes 57

G4-EN25Weight of transported, imported, exported, or treated waste deemed hazardous under the terms of the basel convention2 annex i, ii, iii, and viii, and percentage of transported waste shipped internationally

Yes 57

G4-EN26Identity, size, protected status, and biodiversity value of water bodies and related habitats significantly affected by the organization’s discharges of water and runoff

Yes 18

PRODUCTS AND SERVICES

G4-EN27Extent of impact mitigation of environmental impacts of products and services

Yes 31

G4-EN28Percentage of products sold and their packaging materials that are reclaimed by category

Yes 13, 54

COMPLIANCE

G4-EN29Monetary value of significant fines and total number of non-monetary sanctions for non-compliance with environmental laws and regulations

Yes 57




TRANSPORT

G4-EN30Significant environmental impacts of transporting products and other goods and materials for the organization’s operations, and transporting members of the workforce

Yes 25

OVERALL

G4-EN31 Total environmental protection expenditures and investments by type Yes 57

SUPPLIER ENVIRONMENTAL ASSESSMENT

G4-EN32 Percentage of new suppliers that were screened using environmental criteria Yes 24

G4-EN33Significant actual and potential negative environmental impacts in the supply chain and actions taken

Yes 24

ENVIRONMENTAL GRIEVANCE MECHANISMS

G4-EN34Number of grievances about environmental impacts filed, addressed, and resolved through formal grievance mechanisms

Yes 57

SOCIAL

LABOR PRACTICES AND DECENT WORK

EMPLOYMENT

G4-LA1Total number and rates of new employee hires and employee turnover by age group, gender and region

Yes 48

G4-LA2Benefits provided to full-time employees that are not provided to temporary or parttime employees, by significant locations of operation

Yes 53

G4-LA3 Return to work and retention rates after parental leave Yes 48

G4-LA4Minimum notice periods regarding operational changes, including whether these are specified in collective agreements

Yes 48

OCCUPATIONAL HEALTH AND SAFETY

G4-LA5Percentage of total workforce represented in formal joint management–worker health and safety committees that help monitor and advise on occupational health and safety programs

Yes 48

G4-LA6Type of injury and rates of injury, occupational diseases, lost days, and absenteeism, and total number of work-related fatalities, by region and by gender

Yes 57

G4-LA7Workers with high incidence or high risk of diseases related to their occupation

Yes 57

G4-LA8 Health and safety topics covered in formal agreements with trade unions Yes 48

TRAINING AND EDUCATION

G4-LA9Average hours of training per year per employee by gender, and by employee category

Yes 52

G4-LA10Programs for skills management and lifelong learning that support the continued employability of employees and assist them in managing career endings

Yes 52, 53

G4-LA11Percentage of employees receiving regular performance and career development reviews, by gender and by employee category

Yes 53

DIVERSITY AND EQUAL OPPORTUNITY

G4-LA12Composition of governance bodies and breakdown of employees per employee category according to gender, age group, minority group membership, and other indicators of diversity

Yes 59

EQUAL REMUNERATION FOR WOMEN AND MEN

G4-LA13Ratio of basic salary and remuneration of women to men by employee category, by significant locations of operation

No

Sigma-Aldrich is in process of implementing an upgraded enterprise

management system. This system is expected to go online in 2016 and we will

review ability to report this data at that time.




SUPPLIER ASSESSMENT FOR LABOR PRACTICES

G4-LA14 Percentage of new suppliers that were screened using labor practices criteria Yes 24

G4-LA15Significant actual and potential negative impacts for labor practices in the supply chain and actions taken

Yes 24

LABOR PRACTICES GRIEVANCE MECHANISMS

G4-LA16Number of grievances about labor practices filed, addressed, and resolved through formal grievance mechanisms

Yes 48

HUMAN RIGHTS

INVESTMENT

G4-HR1Total number and percentage of significant investment agreements and contracts that include human rights clauses or that underwent human rights screening

Yes 25

G4-HR2Total hours of employee training on human rights policies or procedures concerning aspects of human rights that are relevant to operations, including the percentage of employees trained”

Yes 48

NON-DISCRIMINATION

G4-HR3 Total number of incidents of discrimination and corrective actions taken Yes 48

FREEDOM OF ASSOCIATION AND COLLECTIVE BARGAINING

G4-HR4Operations and suppliers identified in which the right to exercise freedom of association and collective bargaining may be violated or at significant risk, and measures taken to support these rights”

Yes 24, 48

CHILD LABOR

G4-HR5Operations and suppliers identified as having significant risk for incidents of child labor, and measures taken to contribute to the effective abolition of child labor

Yes 24

FORCED OR COMPULSORY LABOR

G4-HR6Operations and suppliers identified as having significant risk for incidents of forced or compulsory labor, and measures to contribute to the elimination of all forms of forced or compulsory labor

Yes 24

SECURITY PRACTICES

G4-HR7Percentage of security personnel trained in the organization’s human rights policies or procedures that are relevant to operations

Yes 51

INDIGENOUS RIGHTS

G4-HR8Total number of incidents of violations involving rights of indigenous peoples and actions taken

Yes 48

ASSESSMENT

G4-HR9Total number and percentage of operations that have been subject to human rights reviews or impact assessments

Yes 48

SUPPLIER HUMAN RIGHTS ASSESSMENT

G4-HR10 Percentage of new suppliers that were screened using human rights criteria Yes 24

G4-HR11Significant actual and potential negative human rights impacts in the supply chain and actions taken

Yes 24

HUMAN RIGHTS GRIEVANCE MECHANISMS

G4-HR12Number of grievances about human rights impacts filed, addressed, and resolved through formal grievance mechanisms

Yes 48

SOCIETY

LOCAL COMMUNITIES

G4-SO1Percentage of operations with implemented local community engagement, impact assessments, and development programs

Yes 45

G4-SO2Operations with significant actual and potential negative impacts on local communities

Yes 54




ANTI-CORRUPTION

G4-SO3Total number and percentage of operations assessed for risks related to corruption and the significant risks identified

Yes 60

G4-SO4 Communication and training on anti-corruption policies and procedures Yes 61

G4-SO5 Confirmed incidents of corruption and actions taken Yes 60, 61

PUBLIC POLICY

G4-SO6 Total value of political contributions by country and recipient/beneficiary Yes 61

ANTI-COMPETITIVE BEHAVIOR

G4-SO7Total number of legal actions for anti-competitive behavior, anti-trust, and monopoly practices and their outcomes

Yes 60

COMPLIANCE

G4-SO8Monetary value of significant fines and total number of non-monetary sanctions for non-compliance with laws and regulations

Yes 56

SUPPLIER ASSESSMENT FOR IMPACTS ON SOCIETY

G4-SO9Percentage of new suppliers that were screened using criteria for impacts on society

Yes 24

G4-SO10Significant actual and potential negative impacts on society in the supply chain and actions taken

Yes 24

GRIEVANCE MECHANISMS FOR IMPACTS ON SOCIETY

G4-SO11Number of grievances about impacts on society filed, addressed, and resolved through formal grievance mechanisms

Yes 45

PRODUCT RESPONSIBILITY

CUSTOMER HEALTH AND SAFETY

G4-PR1Percentage of significant product and service categories for which health and safety impacts are assessed for improvement

Yes 54

G4-PR2Total number of incidents of non-compliance with regulations and voluntary codes concerning the health and safety impacts of products and services during their life cycle, by type of outcomes

Yes 57

PRODUCT AND SERVICE LABELING

G4-PR3

Type of product and service information required by the organization’s procedures for product and service information and labeling, and percentage of significant product and service categories subject to such information requirements

Yes 54

G4-PR4Total number of incidents of non-compliance with regulations and voluntary codes concerning product and service information and labeling, by type of outcomes

Yes 56

G4-PR5 Results of surveys measuring customer satisfaction Yes 55

MARKETING COMMUNICATIONS

G4-PR6 Sale of banned or disputed products Yes 56

G4-PR7Total number of incidents of non-compliance with regulations and voluntary codes concerning marketing communications, including advertising, promotion, and sponsorship, by type of outcomes

Yes 33

CUSTOMER PRIVACY

G4-PR8Total number of substantiated complaints regarding breaches of customer privacy and losses of customer data

Yes 33

COMPLIANCE

G4-PR9Monetary value of significant fines for non-compliance with laws and regulations concerning the provision and use of products and services

Yes 56


DESCRIPTION CROSS-REFERENCE/DIRECT ANSWEREXTERNAL

ASSURANCE

DMA EC

Economic http://files.shareholder.com/downloads/SIGMA/3003189738x0xS90185-14-28/90185/filing.pdf

Market Presence http://files.shareholder.com/downloads/SIGMA/3003189738x0xS90185-14-28/90185/filing.pdf

Indirect economic impacts http://files.shareholder.com/downloads/SIGMA/3003189738x0xS90185-14-28/90185/filing.pdf

DMA EN

MaterialsSigma-Aldrich values natural resources and how they enable our business. Our primary approach with raw materials, energy and water use is to maximize efficiency and use while minimizing waste.

Energyhttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf

Waterhttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf

Biodiversityhttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf

Emissions, effluents and wastehttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf

Products and servicesSigma-Aldrich continues to develop and deliver new, innovative products for its customers to meet increasing demands for new solutions that are more customized.

Compliancehttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf

Transport Sigma-Aldrich does not transport our products for delivery to customers.

Overallhttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf. Sigma-Aldrich measures success on our environmental performance based on our GC1015 goals.

Supplier Environmental Assessmenthttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/SA_SCOC.pdf

Environmental Grievance Mechanismshttp://files.shareholder.com/downloads/SIGMA/3278460408x0x263293/f2ecb010-9d2f-4965-a93b-b93d1edbc66d/Whistleblower_Policy.pdf

DMA LA

Employment

The Company does not discriminate against any employee, applicant, customer, supplier or other business associate on the basis of race, creed, color, religion, gender, sexual orientation, age, national origin, disability or military status. It is the Company’s intent to provide equal opportunity to all employees, applicants and business associates based on merit.

Labor/management relations

The Company acknowledges employees right to associate with others and form and join organizations of their choice. The Company believes it has the ability to find positive solutions when working and collaborating directly with employees. Additionally, the Company will not discriminate, interfere or retaliate based on employee association.

Occupational health and safetySafety is an integral part of Sigma-Aldrich’s belief system. We are committed to providing a safe working environment for all employees and proud of our safety performance record.

Training and education

Sigma-Aldrich uses the Portfolio Approach to Development. The portfolio or blended approach acknowledges that a single development activity is not effective but a small number of focused activities can be very powerful. Further, it avoids the simplistic thinking of attending a training class and assuming that meaningful development has been accomplished.

Diversity and equal opportunity


Equal remuneration for women and men


Supplier Assessment for Labor Practiceshttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/SA_SCOC.pdf

Labor Practices Grievance Mechanismshttp://files.shareholder.com/downloads/SIGMA/3278460408x0x263289/f9674081-1c36-4030-a23e-73641d80ff8c/Business_Conduct_Policy.pdf

http://files.shareholder.com/downloads/SIGMA/3003189738x0xS90185-14-28/90185/filing.pdf



http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf










http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf.

http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/General_Information/corp_health_and_safety.pdf.

http://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/SA_SCOC.pdf


http://files.shareholder.com/downloads/SIGMA/3278460408x0x263293/f2ecb010-9d2f-4965-a93b-b93d1edbc66d/Whistleblower_Policy.pdf




http://files.shareholder.com/downloads/SIGMA/3278460408x0x263289/f9674081-1c36-4030-a23e-73641d80ff8c/Business_Conduct_Policy.pdf



DESCRIPTION CROSS-REFERENCE/DIRECT ANSWEREXTERNAL

ASSURANCE

DMA HR

Investment and procurement practicesSigma-Aldrich utilizes a Total Cost of Ownership (TOC) model to look at the overall spend required to purchase a given product.

Non-Discrimination

The Company is committed to its core beliefs, which include the treatment of all employees with respect and dignity. Accordingly, the Company does not tolerate harassment, sexual or otherwise, against any employee, applicant, customer, supplier or other business associate. Any behavior that creates an intimidating, hostile or offensive working environment is strictly prohibited.

Freedom of association and collective bargaining

http://www.unglobalcompact.org/participant/17399-Sigma-Aldrich

Child Labor http://www.unglobalcompact.org/participant/17399-Sigma-Aldrich

Prevention of forced and compulsory labor


Security practices


Indigenous rights http://www.unglobalcompact.org/participant/17399-Sigma-Aldrich

Assessment


Human Rights Grievances

Sigma-Aldrich believes it is crucial that individuals who believe that they have been the victims of, or witnesses to, discrimination or harassment report the incident immediately. All reports are kept confidential and the individual may remain anonymous. All complaints will be investigated expeditiously. Any employee found to be guilty of discrimination, harassment or retaliatory practices prohibited by this Policy shall be subject to discipline up to and including termination for cause.

Supplier Human Rights Assessmenthttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/SA_SCOC.pdf

DMA SO

Local communitiesSigma-Aldrich believes that by leveraging the skills and expertise of our employees we can have a measurable impact on the communities we have offices in. As a result, Sigma-Aldrich invests substantial financial and human resources in STEM Education, ground breaking research and economic development through science

Corruptionhttp://files.shareholder.com/downloads/SIGMA/3278460408x0x263289/f9674081-1c36-4030-a23e-73641d80ff8c/Business_Conduct_Policy.pdf

Public policySigma-Aldrich’s involvement in public policy is strictly related to the education of governments, authorities and other relevant bodies by providing information related to the chemical, high technology and life science industry.

Anti-competitive behaviorhttp://files.shareholder.com/downloads/SIGMA/3278460408x0x263289/f9674081-1c36-4030-a23e-73641d80ff8c/Business_Conduct_Policy.pdf

Compliancehttp://files.shareholder.com/downloads/SIGMA/3278460408x0x263289/f9674081-1c36-4030-a23e-73641d80ff8c/Business_Conduct_Policy.pdf

Supplier Impacts on Societyhttp://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/SA_SCOC.pdf

Grievance Mechanism for Impacts to Society


DMA PR

Customer health and safetySigma-Aldrich's worldwide Product Safety staff is comprised of scientists with extensive backgrounds in global compliance regulations. We continually provide comprehensive safety and regulatory data on our Material Safety Data Sheets promoting safe usage and handling of our products

Product and service labelingSigma-Aldrich’s approach to marketing and communications focuses on educating the customer and empowering them identify new and innovative uses for our products in scientific research.

Marketing communicationsSigma-Aldrich’s approach to marketing and communications focuses on educating the customer and empowering them identify new and innovative uses for our products in scientific research.

Customer privacy

We endeavor to protect personal data received from any source in accordance with “Key Principles” that are similar to the requirements of EU and Swiss privacy laws and Safe Harbor programs. Generally speaking, these Principles and this Policy give those whose personal information we collect the right to consent to the collection, use and disclosure of such information, the right to opt-out of any such collection or use and to require the Company to correct inaccurate personal information that the Company maintains. They also require the Company to maintain physical, organizational and technical safeguards to protect personal data from unauthorized access, use, alteration or disclosure and require that third parties that process personal data on our behalf also comply with these obligations

Compliance

Sigma-Aldrich and our employees are committed to complying with the Business Conduct Policy in order for Sigma-Aldrich to maintain the highest business standards. The Business Conduct Policy provides employees guidance around ethical behaviors, compliance and privacy to ensure the continued success of the business. http://files.shareholder.com/downloads/SIGMA/2413469492x0x263289/f9674081-1c36-4030-a23e-73641d80ff8c/Business_Conduct_Policy.pdf


















PRINCIPLE DESCRIPTION PAGE

Principle 1 Businesses should support and respect the protection of internationally proclaimed human rights. 25, 48

Principle 2 Businesses should that they are not complicit in human rights abuses. 48, 49

Principle 3Businesses should uphold the freedom of association and the effective recognition of the right to collective bargaining.

48

Principle 4 Businesses should uphold the elimination of all forms of forced and compulsory labor. 48

Principle 5 Businesses should uphold the effective abolition of child labor 48

Principle 6 Businesses should uphold the elimination of discrimination in respect of employment and occupation. 48

Principle 7 Businesses should support a precautionary approach to environmental challenges. 47, 48, 49

Principle 8 Businesses should undertake initiatives to promote greater environmental responsibility. 11 - 22

Principle 9 Businesses should encourage the development and diffusion of environmentally friendly technologies. 28 - 35

Principle 10 Businesses should work against corruption in all its forms, including extortion and bribery. 58 - 64

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