STRATEGI UNIVERSITAS MA CHUNG DALAM

PENGEMBANGAN DAN PEMANFAATAN

INFORMASI TEKNOLOGI

Leenawaty Limantara Ma Chung Research center for Photosynthetic Pigments

Universitas Ma Chung

*email: leenawaty.limantara@machung.ac.id

Disampaikan dalam Rakor Litbang Pemprov, Pemkab, Pemkot se-Jawa Timur, tgl 25-26

Maret 2014, Twin Hotel, Surabaya

TEKNOLOGI INFORMASI VS INFORMASI TEKNOLOGI

TEKNOLOGI INFORMASI (Information technology, IT):

teknologi apa pun yang membantu manusia dalam membuat, mengubah,

menyimpan, mengomunikasikan dan/atau menyebarkan informasi.

Contoh: bioinformatika, cloud computing, sistim informasi global dll.

INFORMASI TEKNOLOGI: data, pengetahuan, teknik, keterampilan yang memiliki

makna bagi kemajuan peradaban atau pengetahuan yang dikomunikasikan dan

diberdayakan melalui teknologi.

Informacion (Perancis kuno, 1387): garis besar, konsep, ide

Kata benda dari informare: pengetahuan yang dikomunikasikan.

Contoh: informasi geospasial, informasi lalu lintas, informasi teknologi

Teknologi: keseluruhan sarana untuk menyediakan barang-barang yang diperlukan

bagi kelangsungan dan kenyamanan hidup manusia

Ma Chung Research Center for

Photosynthetic Pigments

SUMBER DAYA POTENSIAL:

Rumput laut Mikroalga CPO Bakteria fotosintesis

• Indonesia sebagai satu dari 17

negara mega biodiversitas.

• Surga bagi organisme fotosintesis.

• MRCPP fokus pada penggunaan

„fotosintesis“ di bidang pangan,

kesehatan dan energi terbarukan.

Spesies indigenus

I N F O R M A T I O N through R E S E A R C H

KEKAYAAN ALAM INDONESIA

Indonesia kaya organisme fotosintesis

Rumput laut Mikroalga Sayuran Tumbuhan tingkat tinggi

Bakteria fotosintesis

No. 1 dunia No. 2 dunia

FAKTA terkait problem nasional

• Kekurangan vitamin A (VAD)

• Kekurangan zat besi (IDA)

• Pewarna sintesis

• Krisis Energi

Stafsnes (2013): Characterization and exploitation of marine microbial culture collection

Ma Chung Research Center for

Photosynthetic Pigments

The amount of solar energy that hits the surface of the earth every minute is greater

than the total amount of energy that the world’s human population consumes in a year!

Kiang, N.Y., 2007, Science

Brief, NASA REPORT

Ma Chung Research Center for

Photosynthetic Pigments

TIGA FUNGSI UTAMA KLOROFIL

• Pembersih • Regulator • Regenerator

oxidation

1

2

34

5

67

8

9

10

11

12

13

14

15

15'

14'

13'

12'

11'

10'

9'

8'

7'6'

5'4'

3'

2'

1'

β-Apo-8’-carotenal

β-Apo-12’-carotenal

β-Apo-14’-carotenal

β-Apo-10’-carotenal

CHO

Retinal

CH2OH

Retinol

Gambar: Konversi β-karoten menjadi vitamin A

(Source: Gross, 1991)

Fungsi utama karotenoid:

• Pro Vitamin A

• Antioksidan

• Anti kanker

• Anti inflamasi

• Anti Obesitas

• Anti hiperkolesterol

• Anti diabetes

• Pewarna alami

• Sensitizer (solar cell)

• Biomarker dalam medis

DARAH KITA: Menentukan kesehatan kita

WE NEED RESEARCH

Indigenous species

Excited state properties

National needs

Applied research

Chemical modification

Pigment properties

In vivo

Structure and function interaction

In vitro In situ

stability

Comodity products

Basic research

carotenoid contents in seaweed vs CPO

C42H58O6

1 g wet weight= 0.6 mg fucoxanthin

1 kg wet weight= 600 mg fucoxanthin

Padina australis

1 kg CPO = 500-700 mg carotenoids

(80% β-carotene)

CPO

source: Desalination (2009) 246: 410-413

Function of Fucoxanthin:

1. Anti-obesity

2. Anti-carcinogenic

3. Antioxidants

4. Anti-inflammation

Macro and Micro Algae Products

Raw Material (Nori,etc)

Protein

Bio fuel

Carrageenan

Agarose

Growth Factor Whole Cells as “Food”

Biopigments

Alginate

WE NEED TECHNOLOGIES

extraction purification

encapsulation

Drying methods

preservation

Freeze drying

emulsion

stabilization

Structure and function powder

liquid gel

Bioactive test

packaging

Chemical modification

Ma Chung Research Center for

Photosynthetic Pigments

Why do we have to consider biopigments?

PRICE

Dry seaweeds

IDR 5,000.- IDR 6.000,- /Kg

IDR 350,- 1.000,- /Kg

Info: Antaranews.com

Fucoxanthin

US$ 29.9 per 300 mg mixture (30 capsule)

US$ 19.38 per 300 mg with pomegranate extracts

US$ 220 per 10 mg purity >95% (Sigma Aldrich)

source: Amazon, antaranews.com

US$ 5.99-10.99 (salad)

Product Unit Price Source

Agar agar kg 50.000 Cottonindo

alginate kg 60.000 Industri

carrageenan kg 60.000 Industri

Fucoxanthin mg 200.000 Sigma

Price Comparison

Ratio agar: fucoxanthin 1:4000; Ratio alginate/carrageenan : fucoxanthin:

1:3333

Ma Chung Research Center for

Photosynthetic Pigments

Phycobiliproteins: Fluorescent Pigments for

Medical Diagnostics and Research

High value products, about $5000 US per gram!

Astaxanthin – Market Opportunities

Market sectors Current

market size

Potential market

size (by 2020)

Growth

rate

Animal feed coloring agent salmon, trout, shrimp, chicken feed additive, etc.

Antioxidant nutraceutical

dietary supplement, food colorant, macula pigment enhancer, anti-AMD agent, etc.

Pharmaceutical

super antioxidant, anti-tumor/cancer agent, aging preventing agent, etc.

Cosmetics

sun-block, face cream, body lotion

$300M

$30M

Emerging

Emerging

$800M

$300M

$500M

$30M

~ 10%

~ 30%

> 50%

> 50%

HOW DOES IT WORKS?

Modification of plant nutritional content: increasing the vitamin A content of plants

GGPP Phytoene Lycopene b-carotene Vitamin A

Daffodil phytoene synthase gene Bacterial phytoene desaturase gene Daffodil lycopene b-cyclase gene Endogenous human gene

CAROTENOID PRODUCTIONS IN E. coli

Ma Chung Research Center for

Photosynthetic Pigments

Research Products Theme 1&2: Prototype

Aplikasi Mata Daun • Berfungsi untuk membantu petani dalam

menentukan kebutuhan pupuk nitrogen (Urea, NPK) pada tanaman pangan secara cepat berdasarkan kandungan nitrogen dan klorofil pada permukaan daun yang dihubungkan dengan warna daun.

• Memiliki keunggulan : – Cepat

– Murah

– Lebih obyektif dibandingkan menggunakan Bagan Warna Daun (BWD)

– Hasilnya cukup akurat (80% dibandingkan dengan SPAD Meter Konica Minolta)

• Telah dipublikasikan secara ilmiah di prosiding internasional IEEE

(DOI: 10.1109/ICITEED.2013.6676237)

• Telah didaftarkan pada Dirjen HAKI Kementerian Hukum dan HAM Republik Indonesia dengan no register C00201305715

Ma Chung Research Center for

Photosynthetic Pigments

Peta Kerjasama Riset MRCPP

Peta Kerjasama Konsorsium MRCPP

Peta Kerjasama Industri MRCPP

SELECTED FACILITIES

Ma Chung Research Center for

Photosynthetic Pigments

ONE MIND FOR INDONESIA ONE MIND FOR PEOPLE ONE MIND FOR NATURE

ONE MIND FOR RESEARCH ONE MIND FOR INNOVATION

ONE MA CHUNG R&D CENTER

FOR COMMUNITY DRIVEN-INNOVATION

Investing mind for developing community

JATIM SENTRA PRODUK HILIR RUMPUT LAUT INDONESIA

JATIM SENTRA PRODUK HILIR PIGMEN INDONESIA

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STRATEGI YANG DIKEMBANGKAN:

1.The right people with the right skills and the right

value

2.Memiliki keunikan riset unggulan yang berdampak

luas

3.Jejaring andalan (networking) berbasis ICT

4.Fasilitas andalan

5. Integrasi sistim berbasis ICT

6.Science shop

7.Eksekusi….. Eksekusi …….Eksekusi …..!!!!!!!

QUALITY is never an accident;

it is always the result of

high intention,

sincere effort,

intelligent direction and

skillful execution.

William A. Foster