table s1. clt chimeras shown in figure 2. cause of death (cod) is listed in the third column. mouse...

Table S1. CLT chimeras shown in Figure 2. Cause of death (COD) is listed in the third column.

Mouse ID Age (days) COD Genotype3 46 B cell lymphoma CLT4 57 B cell lymphoma CLT6 46 B cell lymphoma CLT7 59 B cell lymphoma CLT9 45 B cell lymphoma CLT

10 45 B cell lymphoma CLT11 52 B cell lymphoma CLT12 48 B cell lymphoma CLT16 75 B cell lymphoma CLT24 93 B cell lymphoma CLT27 94 B cell lymphoma CLT29 75 B cell lymphoma CLT30 45 B cell lymphoma CLT33 59 B cell lymphoma CLT36 45 B cell lymphoma CLT38 52 No tumor CLT40 56 No tumor CLT44 59 B cell lymphoma CLT47 38 B cell lymphoma CLT52 38 B cell lymphoma CLT53 69 B cell lymphoma CLT

CLT: CD19cre/+; LMP1stopFL/+; TCRb-/-d-/-

Table S2. CLT and CLT; AID-/- chimeras shown in Figure 4. Cause of death (COD) is listed in the third column.

Mouse ID Age (days) COD Genotype75 88 B cell lymphoma CLT79 91 B cell lymphoma CLT81 96 No tumor CLT82 36 B cell lymphoma CLT84 74 B cell lymphoma CLT89 38 B cell lymphoma CLT91 36 B cell lymphoma CLT95 47 B cell lymphoma CLT1 97 B cell lymphoma CLT; AID-/-

3 134 No tumor CLT; AID-/-

6 84 B cell lymphoma CLT; AID-/-














CLT: CD19cre/+; LMP1stopFL/+; TCRb-/-d-/-

Figure S1

B2

20

IgM

B2

20

Thy1.2

ControlThy1.2

Positive control RAG2-/- #3 #10

CLT

#12

Blood

Blood

Figure S2

CD

19

Fas

Spleen

Blood

Control CLT #10 Control CLT #7

Figure S3

A

B

#2

53

2 S

JH4-3

Digest: EcoRI

gl (6.2 kb)

AID+/-

#2

56

8 S

#2

71

8 L

#2

72

1 S

#2

72

3 S

#2

74

5 S

#2

51

5 S

#2

51

5 L

#2

51

9 S

#2

57

1 S

#2

57

1 L

#2

74

3 S

#2

74

3 L

Co

ntr

ol C

D1

9+

Co

ntr

ol L

AID-/-AID+/- AID+/+

n.s.P

erce

nt

surv

ival

Figure S4

CLT chim

eras

(cohort

1)

CLT chim

eras

(cohort

2)

CLT;AID

-/- c

himer

as (c

ohort 1)

0

10

20

30

40

50

n.s.

n.s.

Sp

leen

siz

e (m

m)

Figure S5

JH4-3

Digest: EcoRI

gl (6.2 kb)

kb

10865432

1.5

1.0

0.75

S L S L L S L S L S L L S L L S L S L L

90 98

T S S S

9

S

Control 79 81 58 1 12

CLT

84 96 60

CLT; AID-/-

gl (6.2 kb)

kb

10865432

1.5

1.0

0.75

JH4-3

Digest: EcoRI

Control

S L S S S L S S L LN S S LN S S L S L S L

52 10 30 36 6 16 29 91

T

CLT

L S L

9 3840 33 95

A

B

table s1. clt chimeras shown in figure 2. cause of death (cod) is listed in the third column. mouse...

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