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Interface Between Genomics and Cancer Medicine Sponsoring Institutions st The 1 Global Cancer Genomics Consortium TMC Symposium Save the Date th th 10 Nov - 12 Nov, 2011 (Thursday - Saturday) VENUE : ACTREC (Advanced Centre for Treatment Research and Education in Cancer), Kharghar, Navi Mumbai. Registration Details: Please write to Conference Secretariat (gcgc.actrec.gmail.com) with your contact details and few key words describing your field of specialization Registration is mandatory for attendance.

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Interface Between Genomics and Cancer Medicine

Sponsoring Institutions

stThe 1 Global Cancer Genomics Consortium TMC Symposium

Save the Dateth th 10 Nov - 12 Nov, 2011

(Thursday - Saturday)

VENUE : ACTREC (Advanced Centre for Treatment Research and Education in Cancer), Kharghar, Navi Mumbai.

Registration Details: Please write to Conference Secretariat (gcgc.actrec.gmail.com) with your contact details and few key words describing your field of specialization

Registration is mandatory for attendance.

Dr. Amit Dutt Assistant Professor & Principal Investigator (Scientist E)

Ramalingaswami Fellow (DBT)

ACTREC, Tata Memorial Centre

Kharghar, Navi Mumbai- 410 210 India

[email protected]

Symposium Program Committee:

Venue:

ACTREC

(Advanced Centre for Treatment Research and Education in Cancer)/

TMC (Tata Memorial Centre)

Kharghar, Navi Mumbai - 410 210.

Dr. Rakesh KumarGCGC Symposium Co-Chair

Professor and Chair

Department of Biochemistry & Molecular Biology

The George Washington University, Washington DC, USA

[email protected]

Dr. Sudeep GuptaProfessor of Medical Oncology

Biology Tata Memorial Centre

Dr. E Borges Road, Parel

Mumbai – 400012, India

[email protected]

Dr. Rajendra A BadweGCGC Symposium Co-Chair

Professor of Surgical Oncology

Director, Tata Memorial Centre

Mumbai-400094.

[email protected]

Dr. Jeyanthy Eswaran GCGC Scientific Director

Biochemistry and Molecular

George Washington University,

2300 Eye St NW, Washington, DC 20037

[email protected]

Dr. Vani Parmar Associate Professor of Surgical Oncology

Tata Memorial Centre

Dr. E Borges Road, Parel

Mumbai – 400012, India

[email protected]

Symposium Co-Chairs:

Scientific Program

08:30 am – 08:45 am Opening Remarks:

Dr. Sudeep Gupta,

Welcome note:

08:45 am – 10:15 am Genomic Landscape of Cancer

Dr. Sudeep Gupta, Tata Memorial Hospital, Mumbai, India

Genome-centered Translational Cancer Research

Dr. Rajendra A Badwe,

Next Generation Sequencing in Cancer Research

Dr. Rakesh Kumar,

High Throughput Structural Genomics of Human

Proteins and its contributions to Cancer Research

Dr. Stefan Knapp,

Joint Q/A: 15 min

10:15 am – 10:30 am 2011 GCGC – Key Note Speech

Introduction

Dr. Rajendra A Badwe,

Key Note Speaker. To Be Announced

10:30 am – 12:30 pm Genomic Landscape of Cancer (continued...)

Dr. Jeyanthy Eswaran

Cancer Genomic Consortium – An Indian Perspective

Dr. Abraham Moni Kuriakose,

The Response of Expression Networks to

Gene Copy Number Changes

Dr. Brian Oliver,

Population Genomics and Personalised Medicine

Dr. Uwe Völker,

Tata Memorial Hospital, Mumbai, India

The George Washington University, USA

Structural Genomics Consortium, Oxford University/UK

Tata Memorial Hospital, Mumbai, India

Mazundar-Shaw Cancer Center, India

National Institutes of Health, USA

Institute for Genetics and Functional Genomics, Greifswald, Germany

Tata Memorial Hospital, Mumbai, India

Session 1

Session 2

Moderator:

Moderator:

Thursday, Nov 10, 2011

Exploring the Form and Function of Cancer Genome

07:30 pm – 09:30 pm

Genomic Profiling of Oral Cancers: Clinicopathological and

Prognostic Implications of Genomic Alterations

Dr. Manoj Mahimkar,

Joint Q/A: 15 min

12:30 pm – 01:30 pm Lunch Break

01:30 pm – 03:30 pm Transcriptomic Landscape of Cancer

Inside the Transcriptome

Dr. Jeyanthy Eswaran,

mRNA Expression Profile and Microarray –

Paradigm Shift in Cancer Diagnosis

Dr. Norman H Lee,

microRNAs in Cancer Diagnostics

Dr. Ramkumar Hariharan,

03:45 pm – 06:00 pm Transcriptomic Landscape of Cancer (continued...)

Beyond Expression Patterns mRNA-Seq: Building Transcripts

from Paired- end Sequencing of mRNA, Defining Transcriptomic

Profiling of Various Cancers and Identifying the Origin of

Unaligned Reads

Dr. Jeyanthy Eswaran,

Genetics of Glioma

Dr. Kumaravel Somasundaram,

Glancing through the coding variants of Indian cancer patients

Dr. Rita Mulherkar,

Q/A: 15 min

07:30 pm – 09:30 pm Dinner

The George Washington University, USA

The George Washington University, USA

Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, India

The George Washington University, USA

Indian Institute of Science, Bangalore

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), India

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), India

Session 3

Session 4

08:30 am – 10:15 am Chemical Genomics and Proteomics

Dr. Indraneel Mittra,

Vitiligo, Melanoma and Skin HomeostasisDr. Rajesh S Gokhale,

High throughput Chemical Genomics Enabling Drug Development

Dr. Stefan Knapp,

High throughput Proteomics in infection / Cancer BiologyDr. Uwe Völker,

Tumor suppressors, chromatin modulation and the quiescent stateDr. Jyotsna Dhawan,

Q/A: 15 min

10:15 am – 10:30 am Break

10:30 am – 12:30 pm Genomic Approaches to Cancer Therapeutics

Dr. Rajendra A Badwe & Dr. Rakesh Kumar

Understanding Evolution through Integrative Genomics Dr. Raja Mazumder,

Enriching the Drug Target Pool- Atypical Protein Kinases and

GTPases as Drug Targets

Dr. Jeyanthy Eswaran,

Molecular Therapy in Breast Cancer with Bone Metastases Dr. Luis Costa,

Epidermal growth factor receptor (EGFR) targeted therapy in

lung cancer and beyondDr. Amit Dutt,

12:30 pm – 01:30 pm Lunch

01:30 pm – 03:30 pm Challenges in Design and Analysis of

High Throughput Data

Dr. Rajendra A Badwe & Dr. Rakesh Kumar

Session 5

Session 6

Session 7

Moderator:

Moderators:

Moderator:

Tata Memorial Hospital, Mumbai, India

Institute of Genomics and Integrative Biology, India

Structural Genomics Consortium, Oxford University/UK

Institute for Genetics and Functional Genomics, Greifswald, Germany

The George Washington University, USA

The George Washington University, USA

University of Lisbon Medical Center, Portugal

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), India

Institute for Stem Cell Biology and Regenerative Medicine, India

Friday, Nov 11, 2011

Deconvulating Cancer Complexities: An Integrated Approach

12:00 pm onwards Lunch

Challenges in Experimental Design and Algorithm DevelopmentDr. Srinivas Aluru,

Perspectives in Analysis: Systems, Pathways,

Targets and PredictionDr. Binay Panda,

Perspectives in de novo and reference based assembly of

human genomeDr. Randeep Singh,

Panel Discussion on Bioinformatics

Dr. Rajendra A Badwe & Dr. Rakesh Kumar

Dr. Supratik Chakraborty Dr. Rajendra Joshi

Dr. Stefan Knapp Dr. Brian Oliver

Dr. Rita Mulherkar

07:30 pm – 09:30 pm Dinner

09:00 am – 11:00 am Applications of Cancer Genomic Research

Helping Cancer PatientsDr. Rajendra A Badwe,

Biomarkers for Clinical TrialsDr. Masakazu Toi,

Building New Pathways of ImportanceDr. Rakesh Kumar,

11:00 am – 11:45 am The Next Step

Dr. Rajendra A Badwe, Dr. Rakesh Kumar &

Dr. Stefan Knapp

12:00 pm onwards Lunch

Iowa State University, USA

Ganit Labs, India

Philips Electronic India Limited, Bangalore, India

Tata Memorial Hospital, Mumbai, India

OOTR and Kyoto University Medical Center/Japan

The George Washington University, USA

Moderator:

Panelists:

Session 8

Session 9

Translating Discovery Science to Clinics

Saturday, Nov 12, 2011

International Faculty

Dr. Brian Oliver, Developmental Genomics Section, NIDDK, National Institutes Of Health, Bethesda, USA

Dr. Jeyanthy Eswaran, The George Washington University, USA

Dr. Luis Costa, University of Lisbon Medical Center, Portugal

Dr. Masakazu Toi, OOTR and Kyoto University Medical Center/Japan

Dr. Norman H Lee, The George Washington University, USA

Dr. Raja Mazumder, The George Washington University, USA

Dr. Rakesh Kumar, The George Washington University, USA

Dr. Srinivas Aluru, Iowa State University, USA

Dr. Stefan Knapp, Structural Genomics Consortium, Oxford University, UK

Dr. Uwe Völker, Institute for Genetics and Functional Genomics, Greifswald, Germany

National Faculty

Dr. Abraham Moni Kuriakose, Mazundar-Shaw Cancer Center, India

Dr. Amit Dutt, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), India

Dr. Indraneel Mitra, Tata Memorial Hospital, Mumbai, India

Dr. Jyotsna Dhawan, Institute for Stem Cell Biology and Regenerative Medicine, India

Dr. Kumaravel Somasundaram, Indian Institute of Science, Bangalore

Dr. Manoj Mahimkar, Advanced Center for Treatment, Research and Education in Cancer (ACTREC) India

Dr. Rajendra Badwe, Tata Memorial Hospital, Mumbai, India

Dr. Rajesh S Gokhale, Institute of Genomics and Integrative Biology, Delhi

Dr. Rajiv Sarin, Advanced Center for Treatment, Research and Education in Cancer (ACTREC), India

Dr. Ramkumar Hariharan, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram

Dr. Randeep Singh, Philips Electronic India Limited, Bangalore, India

Dr. Rita Mulherkar, Advanced Center for Treatment, Research and Education in Cancer (ACTREC), India

Dr. Sudeep Gupta, Tata Memorial Hospital, Mumbai, India

Dr. Supratik Chakraborty, Indian Institute of Technology- Bombay, India,

Contact the organizing committeeMr. Madhur Shetty Mr. Rohan ChaubalMr. Ninad Oak Mr. Pratik ChandraniMr. Nimesh Bafna Ms. Ranjini NairMr. Pawan Upadhyay Mr. Yogesh Kembhavi

Conference Secretariat:Dr. Amit Dutt,

KS338C, Cancer Research Institute,

Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)

Tata Memorial Center, Kharghar, Navi Mumbai- 410210

Tel: +91-22-27405056

Email: [email protected]

Sponsoring Institutions

Email [email protected]

Registration Details:Registration is mandatory for attendance.

Please write to Conference Secretariat (gcgc.actrec.gmail.com)

with your contact details and few key words describing your field of specialization