the protagoras study...the protagoras study key findigs from the protagoras study 95.7%93.3% reasons...

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The PROTAGORAS Study Konstantinos P. Donas, Giovanni Torsello Department of Vascular Surgery St. Franziskus Hospital Münster, Germany

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Page 1: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

The PROTAGORAS Study

Konstantinos P. Donas, Giovanni Torsello

Department of Vascular Surgery

St. Franziskus Hospital Münster, Germany

Page 2: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Disclosure

Speaker name: .

Konstantinos Donas..............................................................................

I have the following potential conflicts of interest to report:

Consulting

Employment in industry

Stockholder of a healthcare company

Owner of a healthcare company

Other(s)

I do not have any potential conflict of interest

x

x

Page 3: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Chimney technique

• Current evidence base

Plethora of single-center series

Page 4: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Current evidence base

• Limited number of patients

• Wide variety of treated entities

• Several combinations of off-the-shelf devices

Page 5: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

J Vasc Surg 2016

Page 6: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Devic

es

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128 patients with pararenal pathologies and the intention to treat by Endurant and Advanta V12 as chimney graft

The PROTAGORAS Study

Page 7: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

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Sac regression: 64.8+/-14.6mm60.1+/-16.3mm, p <0.001

New onset of type IA endoleak: 1.6 %

The PROTAGORAS Study

Page 8: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Key findigs from the Protagoras Study

95.7% 93.3%

Page 9: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Reasons for good results in the PROTAGORAS study

1. Devices selection

3. Length of the new neck

2. Oversizing

Page 10: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

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Importance of standard combinations

128 patients treated by Endurant

and balloon expandable chimney grafts

Page 11: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …
Page 12: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

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Importance of standard combinations

41 patients treated by 10

different combinations between

abdominal and chimney grafts

Page 13: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

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9 patients treated by 4 different combinations of abdominal and chimneygrafts

Importance of standard combinations

Page 14: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Importance of new neck length N

ew

neck

length

Neck length/seal zone changed from 4.7mm to

18.7mm

Page 15: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

New

neck

length

Page 16: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Overs

izin

g

Page 17: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Overs

izin

g

Page 18: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

Chimney EVAR performing with Endurant Aortic Endografts

Sufficient landing zone of 20mm

Oversizing 20-30%

Standard combination with balloon

expandable covered stents

Page 19: The PROTAGORAS Study...The PROTAGORAS Study Key findigs from the Protagoras Study 95.7%93.3% Reasons for good results in the PROTAGORAS study 1. Devices selection 3. Length …

The PROTAGORAS Study

Konstantinos P. Donas, Giovanni Torsello

Department of Vascular Surgery

St. Franziskus Hospital Münster, Germany