uk national audit transcatheter aortic valve implantation

75
To Contents UK National Audit Transcatheter Aortic Valve Implantation 1st April 2019 to 31st March 2020 Peter F Ludman BCIS Audit Lead On behalf of British Cardiovascular Intervention Society

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Page 1: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

UK National Audit Transcatheter Aortic Valve

Implantation

1st April 2019 to 31st March 2020

Peter F Ludman

BCIS Audit Lead On behalf of

British Cardiovascular Intervention Society

Page 2: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Transcatheter Aortic Valve Implantation

41 centres

Survey

Page 3: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI

Procedure Numbers

Survey

COVID-19

Page 4: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Leyva, F et al Europace 2021

-64% -41%

-58% -21%

-28% -44%

-43% -45%

-83% -64%

National Lock Down

23rd March

% = change in activity over

3 months cf previous year

Page 5: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI

66 297

557 781

1037 1290

1532

1872

2516

3410

3991

5197

6076

0

1000

2000

3000

4000

5000

6000

7000

Number per Year

91 pmp

Survey

Page 6: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI

40.2

32.8

24.4

18.8 22.2

34.4 35.5

17.0

30.2

16.9

0

5

10

15

20

25

30

35

40

45

Rate of Increase in Procedures

Survey

Page 7: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Europe 2019

Ali N, Open Heart 2021;8:e001547. doi:10.1136/ openhrt-2020-001547

Page 8: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI 2018-19

Country

Treated

Number

of

Centres

Total

TAVI

Population

mid 2019

TAVI

pmp

England 35 5224 5.224 93

Wales 2 250 3.152 79

Scotland 3 400 5.463 73

Northern Ireland 1 202 1.894 107

ALL 41 6076 6.68 91

Survey

Page 9: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI 2018-19

80

65 57

120

78

93

79 73

107

91

0

20

40

60

80

100

120

140

Eng

land

Wale

s

Scotla

nd

No

rthern

Ire

land

UK

To

tal

TAVI pmp

2018-19

2019-20

Survey

Page 10: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020 TAVI Extract

26-04-2020

TAVI 2018-19

Survey

Page 11: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020 TAVI Extract

26-04-2020 TAVI 2018-19

Survey

Page 12: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI pmp by CCG 2018-19

0

50

100

150

200

250

NH

S E

rew

ash C

CG

NH

S N

orw

ich C

CG

NH

S B

radfo

rd D

istr

icts

CC

G

NH

S L

ew

isham

CC

G

NH

S D

on

caste

r C

CG

NH

S D

ors

et C

CG

NH

S H

ull

CC

G

NH

S S

outh

am

pto

n C

CG

NH

S E

ast Lancashire C

CG

NH

S W

igan B

oro

ugh C

CG

NH

S W

arw

ickshire

Nort

h C

CG

NH

S S

andw

ell

and

West

Birm

ingh

am

CC

G

NH

S C

am

brid

geshire a

nd P

ete

rboro

ugh C

CG

NH

S B

olton C

CG

NH

S H

eyw

ood, M

iddle

ton a

nd R

ochdale

CC

G

NH

S C

oventr

y a

nd R

ugby C

CG

NH

S B

ury

CC

G

NH

S B

lackburn

with D

arw

en C

CG

NH

S T

ow

er

Ham

lets

CC

G

NH

S N

ort

h E

ast Lin

coln

shire

CC

G

NH

S N

ort

h K

irkle

es C

CG

NH

S S

om

ers

et C

CG

NH

S N

ort

h L

incoln

sh

ire C

CG

NH

S H

ou

nslo

w C

CG

NH

S S

t H

ele

ns C

CG

NH

S D

urh

am

Dale

s, E

asin

gto

n a

nd S

edgefie

ld…

NH

S E

ast S

tafford

shire C

CG

NH

S W

est S

uffolk

CC

G

NH

S B

ark

ing a

nd D

agenham

CC

G

NH

S M

ore

cam

be B

ay C

CG

NH

S W

est E

ssex C

CG

NH

S B

erk

shire W

est C

CG

NH

S W

arr

ingto

n C

CG

NH

S N

ort

h T

ynesid

e C

CG

NH

S S

outh

Worc

este

rshire C

CG

NH

S S

wale

CC

G

NH

S G

rea

ter

Pre

sto

n C

CG

NH

S W

altham

Fo

rest C

CG

NH

S C

ald

erd

ale

CC

G

NH

S B

asild

on a

nd B

rentw

ood C

CG

NH

S S

outh

Kent C

oast C

CG

NH

S G

louce

ste

rshire C

CG

NH

S B

arn

et C

CG

NH

S N

ort

h D

urh

am

CC

G

NH

S S

outh

Easte

rn H

am

pshire C

CG

NH

S C

am

den C

CG

NH

S R

ichm

ond C

CG

NH

S H

am

ble

ton, R

ichm

ondshire a

nd W

hitby C

CG

NH

S W

est K

ent C

CG

NH

S L

ee

ds C

CG

NH

S E

alin

g C

CG

NH

S S

outh

Cheshire C

CG

NH

S W

irra

l C

CG

NH

S O

xfo

rdshire C

CG

NH

S B

exle

y C

CG

NH

S N

ort

h W

est S

urr

ey C

CG

NH

S S

urr

ey D

ow

ns C

CG

NH

S S

underla

nd C

CG

NH

S N

ott

ing

ham

West C

CG

NH

S T

hanet C

CG

NH

S E

astb

ourn

e, H

ails

ham

and S

eafo

rd C

CG

NH

S N

ort

h S

tafford

shire C

CG

NH

S N

ew

ark

and S

herw

ood C

CG

NH

S S

hro

pshire C

CG

NH

S F

yld

e a

nd W

yre

CC

G

NB Not all Hospital names visible in graphic

Page 13: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI pmp by CCG 2018-19 Lowest 100

0

10

20

30

40

50

60

70

80

NH

S Er

ewas

h C

CG

NH

S H

ard

wic

k C

CG

NH

S B

asse

tlaw

CC

GN

HS

No

rwic

h C

CG

NH

S Sh

effi

eld

CC

GN

HS

Bra

dfo

rd C

ity

CC

GN

HS

Bra

dfo

rd D

istr

icts

CC

GN

HS

Isle

of

Wig

ht

CC

GN

HS

Thu

rro

ck C

CG

NH

S Le

wis

ham

CC

GN

HS

Old

ham

CC

GN

HS

Sou

th N

orf

olk

CC

GN

HS

Do

nca

ster

CC

GN

HS

Milt

on

Key

nes

CC

GN

HS

No

rth

Eas

t H

amp

shir

e an

d F

arn

ham

CC

GN

HS

Do

rset

CC

GN

HS

Wes

t N

orf

olk

CC

GN

HS

Ne

wh

am C

CG

NH

S H

ull

CC

GN

HS

East

Rid

ing

of

York

shir

e C

CG

NH

S M

anch

este

r C

CG

NH

S So

uth

amp

ton

CC

GN

HS

Gre

at Y

arm

ou

th a

nd

Wav

eney

CC

GN

HS

Bar

nsl

ey C

CG

NH

S Ea

st L

anca

shir

e C

CG

NH

S R

oth

erh

am C

CG

NH

S Ta

mes

ide

and

Glo

sso

p C

CG

NH

S W

igan

Bo

rou

gh C

CG

NH

S So

uth

war

k C

CG

NH

S Su

rre

y H

eat

h C

CG

NH

S W

arw

icks

hir

e N

ort

h C

CG

NH

S C

ity

and

Hac

kney

CC

GN

HS

Mer

ton

CC

GN

HS

San

dw

ell a

nd

Wes

t B

irm

ingh

am C

CG

NH

S La

mb

eth

CC

GN

HS

Luto

n C

CG

NH

S C

amb

rid

gesh

ire

and

Pet

erb

oro

ugh

CC

GN

HS

Sou

th W

est

Lin

coln

shir

e C

CG

NH

S M

id E

sse

x C

CG

NH

S B

olt

on

CC

GN

HS

Wan

dsw

ort

h C

CG

NH

S A

ire

dal

e, W

har

fed

ale

and

Cra

ven

CC

GN

HS

Hey

wo

od

, Mid

dle

ton

an

d R

och

dal

e C

CG

NH

S Le

ices

ter

Cit

y C

CG

NH

S P

ort

smo

uth

CC

GN

HS

Co

ven

try

and

Ru

gby

CC

GN

HS

Wes

t H

amp

shir

e C

CG

NH

S H

artl

epo

ol a

nd

Sto

ckto

n-o

n-T

ees

CC

GN

HS

Bu

ry C

CG

NH

S Li

verp

oo

l CC

GN

HS

Bed

ford

shir

e C

CG

NH

S B

lack

bu

rn w

ith

Dar

wen

CC

GN

HS

Bri

sto

l, N

ort

h S

om

erse

t an

d S

ou

th…

NH

S M

ansf

ield

an

d A

shfi

eld

CC

GN

HS

Tow

er H

amle

ts C

CG

NH

S Is

lingt

on

CC

GN

HS

East

Ber

ksh

ire

CC

GN

HS

No

rth

Eas

t Li

nco

lnsh

ire

CC

GN

HS

Dar

lingt

on

CC

GN

HS

Val

e R

oya

l CC

GN

HS

No

rth

Kir

klee

s C

CG

NH

S Sw

ind

on

CC

GN

HS

Co

rby

CC

GN

HS

Som

ers

et C

CG

NH

S N

ott

ingh

am C

ity

CC

GN

HS

Bre

nt

CC

GN

HS

No

rth

Lin

coln

shir

e C

CG

NH

S H

arin

gey

CC

GN

HS

Sutt

on

CC

GN

HS

Ho

un

slo

w C

CG

NH

S So

uth

Tyn

esid

e C

CG

NH

S K

no

wsl

ey C

CG

NH

S St

Hel

en

s C

CG

NH

S W

est

Lan

cash

ire

CC

GN

HS

East

an

d N

ort

h H

ertf

ord

shir

e C

CG

NH

S D

urh

am D

ales

, Eas

ingt

on

an

d S

edge

fiel

d C

CG

NH

S H

alto

n C

CG

NH

S W

est

Lon

do

n C

CG

NH

S Ea

st S

taff

ord

shir

e C

CG

NH

S N

ew

cast

le G

ates

hea

d C

CG

NH

S W

iltsh

ire

CC

GN

HS

Wes

t Su

ffo

lk C

CG

NH

S G

reat

er H

ud

der

sfie

ld C

CG

NH

S C

ante

rbu

ry a

nd

Co

asta

l CC

GN

HS

Bar

kin

g an

d D

agen

ham

CC

GN

HS

Sou

th L

inco

lnsh

ire

CC

GN

HS

Lin

coln

shir

e W

est

CC

GN

HS

Mo

reca

mb

e B

ay C

CG

NH

S Sa

lfo

rd C

CG

NH

S B

ath

an

d N

ort

h E

ast

Som

erse

t C

CG

NH

S W

est

Esse

x C

CG

NH

S N

ort

h N

orf

olk

CC

GN

HS

Val

e o

f Yo

rk C

CG

NH

S B

erks

hir

e W

est

CC

GN

HS

Cro

ydo

n C

CG

NH

S Sc

arb

oro

ugh

an

d R

yed

ale

CC

GN

HS

War

rin

gto

n C

CG

NH

S W

est

Ch

esh

ire

CC

GN

HS

Ne

ne

CC

G

Page 14: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI pmp by CCG 2018-19 Highest 100

0

20

40

60

80

100

120

140

160

NH

S V

ale

of

York

CC

GN

HS

Ber

ksh

ire

Wes

t C

CG

NH

S C

royd

on

CC

GN

HS

Scar

bo

rou

gh a

nd

Rye

dal

e C

CG

NH

S W

arri

ngt

on

CC

GN

HS

Wes

t C

hes

hir

e C

CG

NH

S N

ene

CC

GN

HS

No

rth

Tyn

esid

e C

CG

NH

S G

reen

wic

h C

CG

NH

S K

ings

ton

CC

GN

HS

Sou

th W

orc

este

rsh

ire

CC

GN

HS

Wes

t Le

ices

ters

hir

e C

CG

NH

S D

erb

y an

d D

erb

ysh

ire

CC

GN

HS

Swal

e C

CG

NH

S N

ort

h E

ast

Esse

x C

CG

NH

S A

shfo

rd C

CG

NH

S G

reat

er P

rest

on

CC

GN

HS

Wak

efie

ld C

CG

NH

S So

uth

Tee

s C

CG

NH

S W

alth

am F

ore

st C

CG

NH

S Li

nco

lnsh

ire

East

CC

GN

HS

Bir

min

gham

an

d S

olih

ull

CC

GN

HS

Cal

der

dal

e C

CG

NH

S Ea

st S

urr

ey C

CG

NH

S So

uth

Eas

t St

affo

rdsh

ire

and

Sei

sdo

n P

en

insu

la C

CG

NH

S B

asild

on

an

d B

ren

two

od

CC

GN

HS

No

rth

Ham

psh

ire

CC

GN

HS

Cas

tle

Po

int

and

Ro

chfo

rd C

CG

NH

S So

uth

Ken

t C

oas

t C

CG

NH

S D

evo

n C

CG

NH

S W

olv

erh

amp

ton

CC

GN

HS

Glo

uce

ster

shir

e C

CG

NH

S W

yre

Fore

st C

CG

NH

S En

fiel

d C

CG

NH

S B

arn

et C

CG

NH

S K

ern

ow

CC

GN

HS

Ch

orl

ey a

nd

So

uth

Rib

ble

CC

GN

HS

No

rth

Du

rham

CC

GN

HS

Red

bri

dge

CC

GN

HS

Bla

ckp

oo

l CC

GN

HS

Sou

th E

aste

rn H

amp

shir

e C

CG

NH

S So

uth

end

CC

GN

HS

Fare

ham

an

d G

osp

ort

CC

GN

HS

Cam

den

CC

GN

HS

East

ern

Ch

esh

ire

CC

GN

HS

Du

dle

y C

CG

NH

S R

ich

mo

nd

CC

GN

HS

Hav

erin

g C

CG

NH

S H

erts

Val

leys

CC

GN

HS

Ham

ble

ton

, Ric

hm

on

dsh

ire

and

Wh

itb

y C

CG

NH

S H

amm

ersm

ith

an

d F

ulh

am C

CG

NH

S N

ott

ingh

am N

ort

h a

nd

Eas

t C

CG

NH

S W

est

Ken

t C

CG

NH

S W

alsa

ll C

CG

NH

S N

ort

hu

mb

erla

nd

CC

GN

HS

Leed

s C

CG

NH

S So

uth

Sef

ton

CC

GN

HS

Med

way

CC

GN

HS

Ealin

g C

CG

NH

S B

uck

ingh

amsh

ire

CC

GN

HS

Ipsw

ich

an

d E

ast

Suff

olk

CC

GN

HS

Sou

th C

hes

hir

e C

CG

NH

S H

eref

ord

shir

e C

CG

NH

S C

oas

tal W

est

Suss

ex C

CG

NH

S W

irra

l CC

GN

HS

Sou

th W

arw

icks

hir

e C

CG

NH

S B

rom

ley

CC

GN

HS

Oxf

ord

shir

e C

CG

NH

S St

ock

po

rt C

CG

NH

S G

uild

ford

an

d W

aver

ley

CC

GN

HS

Bex

ley

CC

GN

HS

East

Lei

cest

ersh

ire

and

Ru

tlan

d C

CG

NH

S B

righ

ton

an

d H

ove

CC

GN

HS

No

rth

Wes

t Su

rrey

CC

GN

HS

Hill

ingd

on

CC

GN

HS

Cra

wle

y C

CG

NH

S Su

rrey

Do

wn

s C

CG

NH

S Tr

affo

rd C

CG

NH

S R

edd

itch

an

d B

rom

sgro

ve C

CG

NH

S Su

nd

erla

nd

CC

GN

HS

Ho

rsh

am a

nd

Mid

Su

ssex

CC

GN

HS

Cen

tral

Lo

nd

on

(W

estm

inst

er)

CC

GN

HS

No

ttin

gham

Wes

t C

CG

NH

S H

arro

gate

an

d R

ura

l Dis

tric

t C

CG

NH

S N

ort

h C

um

bri

a C

CG

NH

S Th

anet

CC

GN

HS

Dar

tfo

rd, G

rave

sham

an

d S

wan

ley

CC

GN

HS

Telf

ord

an

d W

reki

n C

CG

NH

S Ea

stb

ou

rne,

Hai

lsh

am a

nd

Sea

ford

CC

GN

HS

Har

row

CC

GN

HS

Staf

ford

an

d S

urr

ou

nd

s C

CG

NH

S N

ort

h S

taff

ord

shir

e C

CG

NH

S So

uth

po

rt a

nd

Fo

rmb

y C

CG

NH

S H

asti

ngs

an

d R

oth

er C

CG

NH

S N

ewar

k an

d S

her

wo

od

CC

G

Page 15: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Centres by Site Code

3 5

110

246

215

39

11 5

214

152

107

126

192

214

189

33 18

168

36

345

116

142

180

69

158

181 187

207

248

60

223

202

459

147

110

264 264

134 139

65

93

0

50

100

150

200

250

300

350

400

450

500

AH

M

AN

T

BA

S

BH

L

BR

I

CH

H

CH

N

CR

O

ER

I

FR

E

GE

O

GJH

GR

L

HA

M

HH

HH

W

HS

C

KC

H

LB

H

LG

I

MO

R

MR

I

NC

R

NG

S

NH

B

PA

P

PL

Y

QE

B

RA

D

RIA

RS

C

RV

B

SB

H

SC

M

SG

H

ST

H

ST

O

UH

W

VIC

WA

L

WY

T

2016

2017

2018-19

2019-20

Survey

Page 16: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Centres by Procedures in 2019-20

3 5 5 11 18

33 36 39

60 65 69

93 107 110 110 116

126 134 139 142 147 152 158

168 180 181 187 189 192

202 207 214 214 215

223

246 248

264 264

345

459

0

50

100

150

200

250

300

350

400

450

500

AH

M

AN

T

CR

O

CH

N

HS

C

HH

W

LB

H

CH

H

RIA

WA

L

NG

S

WY

T

GE

O

BA

S

SG

H

MO

R

GJH

UH

W

VIC

MR

I

SC

M

FR

E

NH

B

KC

H

NC

R

PA

P

PL

Y

HH

GR

L

RV

B

QE

B

ER

I

HA

M

BR

I

RS

C

BH

L

RA

D

ST

H

ST

O

LG

I

SB

H

2016

2017

2018-19

2019-20

Survey

Page 17: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Extract 05-11-2020 v declared

NICOR 5736 (versus declared 6076 in Survey)

TAVI Extract

5-11-2020

Page 18: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Sex

60.6

44.1 48.1 46.4 47 47.5 46.5 45.5 45.5 45.5 44.1 45.6

0

10

20

30

40

50

60

70

% Female

TAVI Extract

5-11-2020

Page 19: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Age Mean

82.7 81.3 81.4 81.3 81 81.2 81 81.2 81.1 81.4 81.4 81.3

0

10

20

30

40

50

60

70

80

90

100

TAVI Extract

5-11-2020

Page 20: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Prior Cardiac Surgery

22.7

29.6 32.1

34.1 32.8 33.4

32.3

28.8 26.5

24.9

20.5 18.4

0

5

10

15

20

25

30

35

40

TAVI Extract

5-11-2020

Page 21: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Prior TAVI

24

21 21

19

20

21

22

23

24

25

2017 2018-19 2019-20

TAVI Extract

5-11-2020

Page 22: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Prior TAVI

TAVI Extract

5-11-2020

• Coronary access post V-in-V TAVI

Page 23: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

PCI Prior or Staged/Hybrid

13.6 13.8 13.1

12.7 13.4

12.9

7.1

6.2 6.6

7.2

4.4 4.7

0

2

4

6

8

10

12

14

16

2014 2015 2016 2017 2018-19 2019-20

% of all TAVI Prior

Staged / Hybrid

TAVI Extract

5-11-2020

Page 24: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI for Aortic Bioprosthetic Valve Failure

66

84

115

132 137

210

0

50

100

150

200

250

2013 2014 2015 2016 2017 2018-19 2019-20

TAVI Extract

5-11-2020

Page 25: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI for Aortic Bioprosthetic Valve Failure

4.3 4.5 4.6

3.9

3.4 3.7

0

1

2

3

4

5

As % of all TAVI

TAVI Extract

5-11-2020

Page 26: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Percutaneous Valves TAVI Valve to treat failing bioprostheses

28

1 1

14

2 1

33

3 2

27

5

3

0

5

10

15

20

25

30

35

Mitral Tricuspid Pulmonary

Number of Procedures

2016

2017-18

2018-19

2019-20

Survey

Page 27: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Percutaneous Valves TAVI Valve to treat failing mitral bioprosthesis

6

5

4 4

2 2

1 1 1 1

0

1

2

3

4

5

6

7

BR

I

RS

C

HA

M

NH

B

SB

H

ST

H

BH

L

KC

H

LG

I

QE

B

Number of Procedures

2019-20

Survey

Page 28: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI

Procedural Details

TAVI Extract

5-11-2020

Page 29: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Device Manufacturer

0

500

1000

1500

2000

2500

3000

Number of TAVIs

EDW

MED

BSC

SJM

SYM

TAVI Extract

5-11-2020

Page 30: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Delivery Approach

5203

0

1000

2000

3000

4000

5000

6000

200

7

200

8

20

09

201

0

201

1

201

2

201

3

201

4

201

5

201

6

201

7

201

8-1

9

201

9-2

0

Number of TAVIs

TF (percut)

TF surgical

TA

SC/Ax

DA

Carotid

Other

TAVI Extract

5-11-2020

Page 31: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Non Percutaneous TF Delivery Approach

0

50

100

150

200

250

Number of TAVIs

TF surgical

TA

SC/Ax

DA

Carotid

Other

TAVI Extract

5-11-2020

Page 32: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Delivery Approach

78 78

85 88 89 90

92 92 93 93 94 95 95 96 96 96 97 97 97 97 97 98 98 98 98 98 98 99 99 100 100 100 100 100 100

0

10

20

30

40

50

60

70

80

90

100

SG

H

MR

I

VIC

ER

I

PLY

BH

L

FR

E

CH

H

PA

P

GR

L

KC

H

RV

B

HA

M

ST

H

SC

M

LG

I

NC

R

RA

D

HH

MO

R

NH

B

QE

B

NG

S

WY

T

GE

O

RS

C

WA

L

SB

H

ST

O

AN

T

BA

S

CH

N

GJH

RIA

UH

W

Transfemoral (%)

TAVI Extract

5-11-2020

Page 33: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Delivery Approach

0 0 0 0 0 0 0 0 0 0 0

1 1 1

1 1 2 2 2 2 2 2 2 3 3 3 3

3 4 4 4

6

8 8

19

0

2

4

6

8

10

12

14

16

18

20

AN

T

BA

S

BH

L

CH

N

GJH

PA

P

PLY

RIA

SG

H

ST

H

UH

W

ST

O

SB

H

NG

S

KC

H

VIC

WA

L

RV

B

RS

C

NH

B

GE

O

QE

B

WY

T

HH

MO

R

RA

D

NC

R

HA

M

LG

I

SC

M

GR

L

ER

I

CH

H

FR

E

MR

I

Subclavian (%)

TAVI Extract

5-11-2020

Page 34: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Delivery Approach

0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1

1

2 3 3 4 4

6

7

10

11

22

0

5

10

15

20

25

AN

T

BA

S

CH

H

CH

N

FR

E

GE

O

GJH

HH

LG

I

MO

R

MR

I

NC

R

NG

S

QE

B

RA

D

RIA

RS

C

SB

H

SC

M

ST

O

UH

W

WA

L

WY

T

NH

B

HA

M

PA

P

GR

L

RV

B

KC

H

ST

H

ER

I

VIC

BH

L

PLY

SG

H

Transapical (%)

TAVI Extract

5-11-2020

Page 35: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Procedures where Cerebral Protection Device Used

1.1 0.9

0.7

1.2

1.9

1.1

4.2

0

0.5

1

1.5

2

2.5

3

3.5

4

4.5

2013 2014 2015 2016 2017 2018-19 2019-20

%

TAVI Extract

5-11-2020

Page 36: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

n=7730

Randomisation 1:1(Claret Sentinel device)

Primary end point: All stroke at 72 hours (or by hospital discharge)

Page 37: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Page 38: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

TAVI Aortic Balloon Valvuloplasty Prior to TAVI Date

174 217 222 264 277 238 247

1354

1652

2288

2844

3365

4371

4756

0

500

1000

1500

2000

2500

3000

3500

4000

4500

5000

Number of TAVI

Procedures Yes

No

TAVI Extract

5-11-2020

Page 39: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Aortic Balloon Valvuloplasty Prior to TAVI Date

11.4 11.6

8.8 8.5

7.6

5.2

3.9

0

2

4

6

8

10

12

14

% of TAVI Procedures

TAVI Extract

5-11-2020

Page 40: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Aortic Balloon Valvuloplasty Prior to TAVI Date

? FRE error

TAVI Extract

5-11-2020

Page 41: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Aortic Balloon Valvuloplasty Prior to TAVI Date

2018-19 2019-20

TAVI Extract

5-11-2020

Page 42: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Aortic Balloon Valuloplasty (not as part of TAVI)

420 473 495

668

789 817 827

687 725

572

0

100

200

300

400

500

600

700

800

900

Survey

Page 43: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Aortic Balloon Valuloplasty (not as part of TAVI – as a % of TAVI)

53.8

45.6

38.4

43.6 42.1

32.5

24.3

17.2 14.0

9.4

0

10

20

30

40

50

60

Survey

Page 44: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI GA v Conscious Sedation

631 835 962

1271 1336 1183

979 744

559 507 49 64 153 260

530

1325

2211

2974

4147

4958

0

1000

2000

3000

4000

5000

6000

2007

2008

20

09

2010

2011

2012

2013

2014

2015

2016

20

17

2018-1

9

2019-2

0

Number of TAVI

Procedures GA

Non GA

TAVI Extract

5-11-2020

Page 45: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Conscious Sedation

1.5

9.5 8.4 7.2 7.1

13.7 17.0

28.4

52.8

69.3

80.0

88.1 90.7

0.0

10.0

20.0

30.0

40.0

50.0

60.0

70.0

80.0

90.0

100.0

TAVI under Conscious

Sedation (%)

TAVI Extract

5-11-2020

Page 46: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI GA v Conscious Sedation

TAVI Extract

5-11-2020

Page 47: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI GA v Conscious Sedation

TAVI Extract

5-11-2020

0 0 0 0 0 2 2 3 3 3 3 3

4 4 5 6 6 6 7 7 8 9 9

10 11 13 13 13

18

27

31

36 38

50

0

10

20

30

40

50

60

AN

TC

HN

FR

ER

IAS

CM

GJH

UH

WQ

EB

ST

OB

AS

WA

LR

SC

HH

HA

MS

BH

LG

IN

GS

RV

BP

AP

NC

RR

AD

ST

HG

RL

PLY

BH

LV

ICE

RI

KC

HC

HH

MR

IS

GH

GE

OW

YT

NH

B

General Anaesthetic (%)

Page 48: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI GA v Conscious Sedation

TAVI Extract

5-11-2020

0

10

20

30

40

50

60

70

80

90

100

AN

T

CH

N

FR

E

RIA

SC

M

GJH

UH

W

QE

B

ST

O

BA

S

WA

L

RS

C

HH

HA

M

SB

H

LG

I

NG

S

RV

B

PA

P

NC

R

RA

D

ST

H

GR

L

PLY

BH

L

VIC

ER

I

KC

H

CH

H

MR

I

SG

H

GE

O

WY

T

NH

B

Conscious Sedation (%)

Page 49: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI GA v Conscious Sedation

2018-19 -> 2019-20

TAVI Extract

5-11-2020

Page 50: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Time to TAVI and Dx

Admission to

TAVI (all)

TAVI to Dx

(all)

LOS (all) LOS

(elective)

Mean (days) 5.4 4.4 8.8 5.7

Median (days) 2.0 2.2 4 3

TAVI Extract

5-11-2020

Page 51: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI Length Of Stay

TAVI Extract

5-11-2020

Page 52: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Page 53: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

2015 Poland and France

2017 Portugal

2020 UK

https://www.valveforlife.co.uk/clinician-resources

Page 54: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

https://www.valveforlife.co.uk/clinician-resources

Page 55: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Valve for Life Proposed Benchmark Standards

https://www.valveforlife.co.uk/clinician-resources

Page 56: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Aortic Stenosis Prognosis

Ali N, et al. Open Heart 2021;8:e001547

Page 57: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Valve for Life Proposed TAVI pathway

https://www.valveforlife.co.uk/clinician-resources

Page 58: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

TAVI

Complications

TAVI Extract

5-11-2020

Page 59: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Implantation of PPM Due to TAVI All procedures

11.32

9.25 9.69

0

2

4

6

8

10

12

%

Pre-TAVI prophylactic

Per-TAVI

Post-TAVI

TAVI Extract

5-11-2020

Page 60: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Implantation of PPM Due to TAVI Edwards Sapien

6.3 6.1

6.9 7.5 7.8 7.8

7

0

1

2

3

4

5

6

7

8

9

%

Pre-TAVI prophylactic

Per-TAVI

Post-TAVI

TAVI Extract

5-11-2020

Page 61: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Implantation of PPM Due to TAVI Medtronic

14.4 15.4

18.3 18.5 18.4

16.2 14.8

0

2

4

6

8

10

12

14

16

18

20

%

Pre-TAVI prophylactic

Per-TAVI

Post-TAVI

TAVI Extract

5-11-2020

Page 62: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Post TAVI Aortic Regurgitation

62.4

57.4 55.2

60.6

34.2

39.1 41

36.5

3.2 3.2 3.6 2.7 0.2 0.3 0.2 0.3

0

10

20

30

40

50

60

70

2016 2017 2018-19 2019-20

%

None

Mild

Moderate

Severe

TAVI Extract

5-11-2020

Page 63: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Post TAVI Aortic Regurgitation

62.4

34.2

3.2

0.2

57.4

39.1

3.2 0.3

55.2

41

3.6

0.2

60.6

36.5

2.7 0.3

0

10

20

30

40

50

60

70

None Mild Moderate Severe

%

2016

2017

2018-19

2019-20

TAVI Extract

5-11-2020

Page 64: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Bail out PCI

0.4

0.27

0.45

0.41

0

0.05

0.1

0.15

0.2

0.25

0.3

0.35

0.4

0.45

0.5

2016 2017 2018-19 2019-20

%

TAVI Extract

5-11-2020

Page 65: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Tamponade

3

5.3

2.1

1.7 1.9

1.7

2.2 2.4

1.6 1.4

1.2 0.94 0.9

0

1

2

3

4

5

6

%

TAVI Extract

5-11-2020

Page 66: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Tamponade

TAVI Extract

5-11-2020

6

26

2

7

3

0

5

10

15

20

25

30

35

40

Surgical intervention Percutaneous intervention

n Not recorded

Died

Alive

Page 67: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Major Vascular Access Complication

3.1 3.1

3.3

2

2.3

2.83

2.3

0

0.5

1

1.5

2

2.5

3

3.5

2013 2014 2015 2016 2017 2018-19 2019-20

%

TAVI Extract

5-11-2020

Page 68: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Major Bleeding

0.87

1.1

0.68

1.73

1.44 1.57

4.13

3.83

3.26

0

0.5

1

1.5

2

2.5

3

3.5

4

4.5

2017 2018-19 2019-20

%

Life Threatening / Disabling

Major

Minor

TAVI Extract

5-11-2020

Life Threatening / Disabling = BARC 5, BARC 3b and 3c

Major = BARC 3a

Minor = BARC 2 or 3a according to severity

Page 69: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

Conversion to Full Sternotomy

0.3

0.15

0.1

0

0.05

0.1

0.15

0.2

0.25

0.3

0.35

2019-20

%

Valve surgery

Haemorrhage

Other reason

TAVI Extract

5-11-2020

n=16 n=8 n=3

N=27

Page 70: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

To Contents

Data extract

20-10-2020

Conversion to Full Sternotomy

10

7

2

3

4

1

0

2

4

6

8

10

12

14

16

18

Valve Surgery Haemorrhage Other reason

n

Not recorded

Died

Alive

TAVI Extract

5-11-2020

Page 71: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

In Hospital CVA

3

2 2

2.2

2.6

2.3

2.1

0

0.5

1

1.5

2

2.5

3

3.5

2013 2014 2015 2016 2017 2018-19 2019-20

%

TAVI Extract

5-11-2020

Page 72: UK National Audit Transcatheter Aortic Valve Implantation

2019-20 data

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Data extract

20-10-2020

In Hospital CVA

Myat A et al. CCI 2020

• 8,652 TAVI procedures were performed from 2007 to 2015

• CVA in 205

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2019-20 data

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Data extract

20-10-2020

In Hospital Mortality

4.7

3.5

2.5

1.8 2 2

1.3

0

0.5

1

1.5

2

2.5

3

3.5

4

4.5

5

2013 2014 2015 2016 2017 2018-19 2019-20

%

TAVI Extract

5-11-2020

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2019-20 data

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Data extract

20-10-2020

Summary

• Rate has increased to 91 pmp

– UK low relative to Europe

– Marked UK regional variation

• Mean age and sex ratio unchanged

• Variation in TAVI practice

– Use of prior Aortic Balloon Valvuloplasty

– Conscious sedation (rather than GA)

– Vascular access

– Length of stay

• Outcomes

– Low rates of significant AR

– CVA remains < 3%

– Falling mortality (<2% this audit period)

• Developments

– Valve for Life initiative, Randomised trial of cerebral protection

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2019-20 data

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Data extract

20-10-2020

Acknowledgment

• NICOR

– Sue Manuel (Senior Developer – Qreg5)

– Unfunded continuation of database support