understanding in vitro fertilization

7/31/2019 Understanding in Vitro Fertilization

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Understanding IVFDr Parul Katiyar, MS

Consultant Infertility & Reproductive Medicine,Fortis Bloom IVF Center, New Delhi

[email protected]
mailto:[email protected]:[email protected]


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Assisted Reproductive Technology( ART)

ART refers to all techniques involving direct retrievalof oocytes (eggs) from the ovary

ART procedures include IVF GIFT ZIFT ICSI

IMI The simplest ART procedure, IVF has been around for

over 20 years and is perhaps the most commonlyrecognized ART of all procedures

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http://www.bloomivf.com/index.html


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Stages of IVF Process

Premedication Ovulation Induction Follicular Monitoring Blood Tests for Hormonal Assessment Egg Retrieval Fertilization Of Egg and Sperm (Embryology) Embryo Transfer

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Methodology of Ovulation Induction OI refers to the use of medications to stimulate

ovaries to produce one or more eggs Involves taking injections known as gonadotropins;

common brands are: Gonal F/ Reacagon/ Menogon etc. Injections have to be taken for 11-14 days

continuously, to stimulate the growth of eggs Dose of hormones has to be individualized

depending upon diagnosis, age, ovarian reserve, drugbeing used and numerous other factors The success of ovulation induction in achieving a

pregnancy is highly variable

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Follicular Monitoring Follicular monitoringgenerally starts after taking

the injections for 4-5 daysand is usually done onalternate days

Involves regular transvaginalultrasounds, done in themorning hours starting at 9am

You are needed to come to

the ultrasound departmentstraight, at right time There are 5-6 such serial

ultrasounds done overperiod of 11-14 days

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Hormonal assessment Blood Estradiol (E2):

Typically done beforebeginning the hormoneinjections; thereafter on5 th day of stimulationand then as and whenrequired

Helps in correlating andestimating bodysresponse to hormoneinjections

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Egg Retrieval Is a day care procedure Is done under short

general anesthesia Using a special needle,

through vagina Done under ultrasound

guidance No cut onbody

Takes almost half an hour Patient is discharged on

the same day within 6-8hrs

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Embryo Transfer

Involves putting theembryo inside theuterus under

ultrasound guidance Done after 48-72 hrs of

egg retrieval No admission / Fasting

required Again no cut on body

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Success varies with many factors, including the number of embryos that are transferred

With one embryo transferred, there is ~10% chance of successful implantation; with two embryos, this rateincreases to 25-30%, with the success rate peaking with3-4 embryos

At Fortis Bloom IVF centre, overall IVF pregnancy rate is

35-50% Whatever the success rates, there will be some failures

and each patient may statistically require up to 3 attempts

at IVF

Success Rates

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Embryo freezing

Technology where the embryos formed in 1 cycle canbe frozen for future usage

Saves the need for repeated stimulation and

stringent monitoring Success rates are comparable to fresh embryo

transfer cycle

Helps in improving success rates in cycles whereendometrial lining is not good Also useful in hyperstimulated cycles

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Team At Bloom IVF

Senior consultants Dr HD Pai Dr Nandita Palshetkar

Consultants Dr Parul Katiyar Dr Jyoti Bali

Support Staff Ms Anchal Ms Navneet

Embryologists Dr Sudesh Kamath Dr Sandeep Joshi Ms Rekha

Radiologists Dr S Khandwala Dr S Mahimkar

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understanding in vitro fertilization

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