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Update on the Immunization Practices Advisory Committee (IPAC) 2018 WHO PDVAC Meeting Geneva, Switzerland Tania Cernuschi, STF Team Lead, EPI/IVB June 2018

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Page 1: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on the

Immunization Practices

Advisory Committee (IPAC)

2018 WHO PDVAC Meeting

Geneva, Switzerland

Tania Cernuschi,

STF Team Lead, EPI/IVB

June 2018

Page 2: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

2

IPAC - Overview

Mandate (as of May 2017)

– to provide independent and expert advice to the WHO/IVB Director on how to

strengthen immunization service delivery and programme management to:

1. Leverage innovative approaches and technologies that can maximize reach

and equitable access to vaccines up to the last mile, and to

2. Optimize operational efficiency and management of vaccination programmes

at country level.

– Main focus: Guidance documents & tools used in national immunization programs

• Addressing questions of feasibility and acceptability

– No executive, regulatory, or decision-making function on behalf of WHO

Members & Operations

– 11 core members, including chair: Dr Chris Morgan

– Working Groups: Delivery Technologies + Controlled Temperature Chain

– Annual meetings + Teleconferences + Online Discussion Group + Bulletins

2 Update on IPAC for PDVAC | June 2018

Page 3: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

3

IPAC Quarterly Bulletins

June 2018

Page 4: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

4

IPAC – highlights of the past year

Guidance on definition and concept development of Total System

Effectiveness (TSE) : July 2017 TC

HPV Pilot Study using a Controlled Temperature Chain (CTC) –

review and endorsement of methodology : via CTC-WG

Revision of measles/rubella (MR) microarray patch (MAP) target

product profile (TPP) : via DT-WG

Programmatic inputs at all meetings of the Global Advisory

Committee for Vaccine Safety (GACVS)

Selective Vaccination during SIAs in different settings- input on

optimal approach : Q1 2018

4 Update on IPAC for PDVAC | June 2018

Page 5: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

5

IPAC July 2018 Meeting – Agenda Highlights (Meeting report will be made available on IPAC page of IVB website by late August)

I. Innovation for Improved Coverage and Equity - Evaluating barriers to effective immunization

- Defining the country use case for Total System Effectiveness

- Country consultations in support of the Vaccine Innovation Prioritization Strategy (VIPS)

II. Optimizing Vaccine Supply - Global immunization financing update

- Improving vaccine access

- EVM 2.0 Progress

III. Controlled Temperature Chain (CTC) - Lessons learned from CTC-HPV Pilot efforts in Uganda + endorsement of new guidelines

- Plans for CTC-OCV Pilot and roll-out : discussion on methodology

- Challenges around Hepatitis B birth dose licensure for CTC

IV. Delivery Technology (DT) - Report on April 2018 Consultation on measles/rubella (MR) micro-array patch (MAP)

- Other DT WG progress/consultations: Uniject, Apiject, delivery of DNA vaccines by

electroporation, etc.

V. Immunization Advisory Committee updates

5 Update on IPAC for PDVAC | June 2018

Page 6: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

6

2017-2018 Priorities for IPAC

1. Innovations for equitable immunization coverage - CTC

- Delivery Technologies

incl. programmatic aspects & health worker training

- Total Systems Effectiveness + VIPS **shared role with PDVAC** - Needles/Syringe practices 2. Immunization Service Delivery and Programme Management - Integrated health services and integrated programme management

- Second+ Year of Life

- Missed Opportunities for vaccination

- Vaccine Shortages

- Strengthening Community Engagement/Demand

- Implementation (framework for vaccine policy recommendations)

- Equity & Coverage

6 Update on IPAC for PDVAC | June 2018

Page 7: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

7

Programmatic definition of

Controlled Temperature Chain (CTC)

DEFINITION: A specific set of conditions allowing for a vaccine

to be stored and transported outside of the traditional 2° to 8°C cold

chain 1) One excursion, just prior to administration

2) Specifically limited duration (at least 3 days)

3) Ambient temperatures up to 40°C+

4) Full validation =

Tested (for safety & stability)

Licensed

Prequalified

5) Key tools = VVM + Peak Threshold Temperature Indicator

PRIORITIES: Current focus campaigns and special strategies

7 Update on IPAC for PDVAC | June 2018

Page 8: Update on the Immunization Practices Advisory Committee (IPAC) · Programmatic inputs at all meetings of the Global Advisory Committee for Vaccine Safety (GACVS) Selective Vaccination

Update on IPAC for PDVAC | June 2017

8

THANK YOU

For more information: http://www.who.int/immunization/programmes

_systems/policies_strategies/ipac/en/

Or contact IPAC Secretariat: Anna-Lea Kahn

[email protected]

8 Update on IPAC for PDVAC | June 2018

http://www.who.int/immunization/programmes_systems/policies_strategies/ipac/en/
http://www.who.int/immunization/programmes_systems/policies_strategies/ipac/en/
http://www.who.int/immunization/programmes_systems/policies_strategies/ipac/en/
mailto:[email protected]

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