who unicef immunization coverage estimates 2020 revision

24
Document last revised: 16 July 2021 1 WHO UNICEF Immunization Coverage Estimates 2020 revision (completed 15 July 2021) The estimates are based on data and information available to WHO and UNICEF as of 6 July 2021. The data are available from both WHO and UNICEF web sites: https://immunizationdata.who.int/ and http://www.data.unicef.org/child-health/immunization. An explanation how to interpret the country profiles is also available: http://www.who.int/entity/immunization/monitoring_surveillance/routine/coverage/U ser_Ref_Country_Reports.pdf. Methodology: Each year WHO and UNICEF jointly review reports submitted by Member States regarding national immunization coverage, finalized survey reports as well as data from the published and grey literature. Based on these data, with due consideration to potential biases and the views of local experts, WHO and UNICEF attempt to distinguish between situations where the available empirical data accurately reflect immunization system performance and those where the data are likely to be compromised and present a misleading view of immunization coverage while jointly estimating the most likely coverage levels for each country. WHO and UNICEF estimates are country-specific; that is to say, each country's data are reviewed individually, and data are not borrowed from other countries in the absence of data. Estimates are not based on ad hoc adjustments to reported data; in some instances, empirical data are available from a single source, usually the nationally reported coverage data. In cases where no data are available for a given country/vaccine/year combination, data are considered from earlier and later years and interpolated to estimate coverage for the missing year(s). In cases where data sources are mixed and show large variation, an attempt is made to identify the most likely estimate with consideration of the possible biases in available data. Due to the COVID-19 pandemic, the data collection response rate is lower than in recent years. For the 15 July 2021 release, no estimate for 2020 was made for countries that did not report coverage date by 6 July 2021. WHO and UNICEF have extended the data collection for the 2020 WUENIC revision to give countries extra time to report, complement, or correct already submitted data. UNICEF and WHO will release an update of the WUENIC 2020 revision in September/October2021

Upload: others

Post on 24-Nov-2021

8 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

1

WHO UNICEF Immunization Coverage Estimates

2020 revision (completed 15 July 2021)

The estimates are based on data and information available to WHO and UNICEF as of

6 July 2021.

The data are available from both WHO and UNICEF web sites:

https://immunizationdata.who.int/

and http://www.data.unicef.org/child-health/immunization.

An explanation how to interpret the country profiles is also available:

http://www.who.int/entity/immunization/monitoring_surveillance/routine/coverage/U

ser_Ref_Country_Reports.pdf.

Methodology:

Each year WHO and UNICEF jointly review reports submitted by Member States

regarding national immunization coverage, finalized survey reports as well as data

from the published and grey literature. Based on these data, with due consideration to

potential biases and the views of local experts, WHO and UNICEF attempt to

distinguish between situations where the available empirical data accurately reflect

immunization system performance and those where the data are likely to be

compromised and present a misleading view of immunization coverage while jointly

estimating the most likely coverage levels for each country.

WHO and UNICEF estimates are country-specific; that is to say, each country's data

are reviewed individually, and data are not borrowed from other countries in the

absence of data. Estimates are not based on ad hoc adjustments to reported data; in

some instances, empirical data are available from a single source, usually the

nationally reported coverage data. In cases where no data are available for a given

country/vaccine/year combination, data are considered from earlier and later years

and interpolated to estimate coverage for the missing year(s). In cases where data

sources are mixed and show large variation, an attempt is made to identify the most

likely estimate with consideration of the possible biases in available data.

Due to the COVID-19 pandemic, the data collection response rate is lower than in

recent years. For the 15 July 2021 release, no estimate for 2020 was made for

countries that did not report coverage date by 6 July 2021. WHO and UNICEF have

extended the data collection for the 2020 WUENIC revision to give countries extra

time to report, complement, or correct already submitted data. UNICEF and WHO

will release an update of the WUENIC 2020 revision in September/October2021

Page 2: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

2

A detailed explanation of the estimation methods is provided in following three

publications:

Burton A, Monasch R, Lautenbach B, Gacic-Dobo M, Neill M, Karimov R, Wolfson

L, Jones G, Birmingham M. WHO and UNICEF estimates of national infant

immunization coverage: methods and processes. Bull World Health Organ.

2009;87(7):535-41.

Burton A, Kowalski R, Gacic-Dobo M, Karimov R, Brown D. A Formal

Representation of the WHO and UNICEF Estimates of National Immunization

Coverage: A Computational Logic Approach. PLoS ONE 2012;7(10): e47806.

doi:10.1371/journal.pone.0047806

Brown D, Burton A, Gacic-Dobo M, Karimov R An Introduction to the Grade of

Confidence in the WHO and UNICEF Estimates of National Immunization Coverage

The Open Public Health Journal, 2013, 6, 73-76

Disclaimer

All reasonable precautions have been taken by the World Health Organization and

United Nations Children's Fund to verify the information contained in the WUENIC.

However, the WUENIC are distributed without warranty of any kind, either expressed

or implied. The responsibility for the interpretation and use of the material lies with

the reader. In no event shall the World Health Organization or United Nations

Children's Fund be liable for damages arising from its use.

Vaccines recently added to the estimation production cycle

Second dose of measles containing vaccine

Beginning with the 2013 revision (completed in July 2014), WHO and UNICEF

produce coverage estimates for the second dose of measles containing vaccine from

2000 onwards for countries where a second dose is recommended in the national

immunization schedule for universal use and where empirical data are available for at

least one year since introduction in the schedule.

Coverage estimates for the second dose of measles-containing vaccine (MCV2) are

produced for the age cohort according to the administration recommended in national

immunization schedule of each country. Global and regional coverage estimates are

produced for vaccinations by 2 years of age and by the nationally recommended age.

Currently, much of the information available is nationally reported coverage, as only

few countries have included the second dose of measles-containing vaccine in

nationally representative coverage surveys.

Page 3: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

3

Hepatitis B birth dose

Beginning with the 2013 revision (completed in July 2014), WHO and UNICEF

produce coverage estimates for the hepatitis B birth dose from 2000 onwards for

countries where the vaccine dose is recommended in the national immunization

schedule for universal use and where empirical data are available for at least one year

since introduction in the schedule.

Hepatitis B birth dose estimates are produced for doses given within 24 hours after

birth. Currently, survey results for Hepatitis B birth dose are scant and in many

instances the surveys either do not appropriately collect or report on the strict timing

for administration. WHO and UNICEF estimates for Hepatitis B birth dose may well

be overestimated, especially for countries with low rates of institutionalized births.

Inactivated polio vaccine

WHO and UNICEF began producing estimates of vaccination coverage for

inactivated polio vaccine (IPV) in 2015 following the Global Polio Eradication

Initiative (GPEI) strategic plan recommendation that at least one full dose, or two

fractional doses, of IPV be included in routine immunization schedules as a strategy

to mitigate the potential consequences should any re-emergence of type 2 poliovirus

occur following the withdrawal of Sabin type 2 strains from oral polio vaccine

(OPV). In April 2016 the switch from trivalent OPV (tOPV) to bivalent OPV (bOPV)

began, thereby removing the type 2 component from immunization programmes

worldwide in order to minimize the risk of continued type 2 circulating vaccine-

derived poliovirus (cVDPV) cases and vaccine associated paralytic polio (VAPP). In

2018-19, >2-doses of IPV, whether full or fractional, are recommended by the

Strategic Advisory Group of Experts on Immunization (SAGE) to induce long-lasting

protection against poliomyelitis1.

Beginning with the 2015 revision (completed in July 2016), IPV coverage estimates

were produced for countries using both IPV and OPV in their immunization

programme. Beginning with the 2016 revision, IPV estimates are produced for all

countries using IPV and reporting IPV coverage data regardless of OPV use.

Estimated global and regional average coverage levels are produced only for those

countries where both OPV and IPV are included in the national immunization

schedule.

The production of IPV coverage estimates results in no change on the estimated

coverage levels for the third dose of polio (Pol3). For countries recommending routine

immunization with a primary series of three doses of IPV alone, the WHO and

UNICEF estimates of coverage for Pol3 are equivalent to estimated coverage with

1 https://www.who.int/teams/immunization-vaccines-and-biologicals/policies/position-papers/polio

Page 4: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

4

three doses of IPV. For countries with a sequential schedule, estimated coverage for

Pol3 is based on that for the third dose of polio vaccine regardless of vaccine

presentation.

During 2015-17 revisions (i.e., estimates for 2015, 2016 and 2017), estimates for IPV

reflect coverage with at least one routine full dose, or two fractional doses, of IPV

(IPV1) among infants <1 year of age. With the new recommendation for >2-doses of

IPV, whether full or fractional, the interpretation of WHO and UNICEF estimates for

IPV have become more complex as of the 2018 revision with regards to what the

estimates reflect.

For IPV1, in the 2016 revision, WHO and UNICEF produced estimates for individual

countries, but not regional or global coverage estimates given that countries were still

introducing this vaccine and IPV supply was unreliable. Beginning with the 2017

revision, WHO and UNICEF produced regional and global average coverage

estimates for IPV1 for countries using OPV.

During 2016 and 2017 (mostly), with the occurrence of global IPV supply disruptions,

some countries began implementing fractional doses of IPV. The quality of reporting

first and second fractional doses is largely unknown; however, when countries did

report coverage for the first and second fractional dose, the WHO and UNICEF

estimate for IPV reflected coverage for the second fractional dose. This remained the

practice since the 2018 revision (completed during July 2019). However, with the new

SAGE recommendations, interpretation of what IPV1 reflects as of the 2018

WUENIC revision is not straightforward. See the table below.

IPV bOPV Protection

1 fractional dose >3 doses Primed for protection against strain 2; Protected against strain 1 and 3

>2 fractional doses >3 doses Protected against strains 1, 2 and 3

1 full dose >3 doses Primed for protection against strain 2; Protected against strain 1 and 3

>2 full doses >3 doses Protected against strains 1, 2 and 3

1 fractional dose <3 doses Primed for protection against strains 1, 2 and 3

>2 fractional doses <3 doses Primed for protection against strain 1 and 3; Protected against strain 2

>2 full doses <3 doses Primed for protection against strain 1 and 3; Protected against strain 2

1 full dose <3 doses Primed for protection against strains 1, 2 and 3

In some instances, estimated IPV1 coverage may reflect the percentage of infants in a

country who received two fractional IPV doses, in which case these children are

protected against strains 1, 2 and 3 if the child has received bOPV3. In other

instances, estimated IPV1 coverage may reflect the percentage of infants in a country

who received one full dose of IPV, likely through a combination penta- or hexa-valent

vaccine.

Further discussions are planned during 2021 to better disentangle the complexities

that have arisen. It may well be that in next revisions, the WHO and UNICEF

Page 5: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

5

estimates of IPV1 coverage will reflect the percentage of infants who are primed for

protection against strains 1, 2 and 3 if the child has not received three doses of bOPV;

or, if the child has received bOPV3, the estimates will reflect the percentage of infants

who are primed for protection against strain 2 and protected against strains 1 and 3. In

countries using IPV and no OPV, only children who receive at least two doses of IPV

are considered fully protected against strains 1, 2 and 3.

Cautious interpretation of IPV1 estimates is required at this time.

Rubella containing vaccine

Also beginning with the 2015 revision, WHO and UNICEF produce coverage

estimates for rubella containing vaccine for those countries where the vaccine is

included in the national immunization schedule. Estimates are made for the entire

time series from 1980. The approach taken to estimate coverage for rubella containing

vaccine is as follows:

• If rubella-containing vaccine is recommended in year Y and rubella containing

vaccine is administered with the first dose of measles-containing vaccine, then

the estimate for rubella containing vaccine for year Y is equal to the estimated

coverage for the first dose of measles-containing vaccine in year Y.

• If rubella-containing vaccine is recommended in year Y and rubella-

containing vaccine is administered with the second dose of measles-containing

vaccine, then the estimate for rubella containing vaccine for year Y is equal to

the estimated coverage for the second dose of measles-containing vaccine in

year Y.

Given that estimates for rubella containing vaccine are based on estimates for either

MCV1 or MCV2, reported country coverage are not included in the country reports in

order to avoid confusion by readers as to how such data are incorporated.

Global and regional average estimates have been produced for rubella-containing

vaccine since the 2015 revision.

Starting with the 2016 revision, the minor layout changes were made to the country

profile report:

• A detailed explanatory note was added to the front page.

• The order of the explanatory text was changed presenting the most recent year

on the top of the page, as opposed to the first year in the graph on the top.

Country response to the Joint Reporting Form on Immunization, 2021 (data for 2020)

During 2021 by 6 July, reported immunization service delivery performance data

were received through the Joint Reporting Form on Immunization from 160 of 195

WHO/UNICEF Member States.

Page 6: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

6

List WHO and UNICEF member states with no report submitted as of . 6 July2021 .

Country ISO-3 CountryCode

Albania alb

Armenia arm

Belgium bel

Bahamas bhs

Bosnia and Herzegovina bih

Cook Islands cok

Cyprus cyp

Czechia cze

Germany deu

Algeria dza

Fiji fji

France fra

Gambia gmb

Guinea-Bissau gnb

Croatia hrv

Hungary hun

Iceland isl

Republic of Korea kor

Kuwait kwt

Morocco mar

Monaco mco

Marshall Islands mhl

North Macedonia mkd

Namibia nam

Niue niu

Netherlands nld

Oman omn

Peru per

Poland pol

Portugal prt

Singapore sgp

Serbia srb

Sao Tome and Principe stp

Thailand tha

Trinidad and Tobago tto

For 2020 exceptionally estimates were only made for countries with reported data.

Therefore there are no estimates available for the above listed 35 countries for the

year of 2020. If reports become available exceptional update will be issued later in the

year.

Page 7: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

7

Summary of WUENIC values for the third dose of DTP containing vaccine

WUENIC = reported coverage 118 (61%) countries

28 are supported by a survey within the last 5 years

52 had surveys more than 5 years ago

1 country has had no surveys

WUENIC < reported coverage 36 (18%) countries;

25 countries with >10%-point difference,

8 with >5% and <10% -point difference

WUENIC > reported coverage 6 (3%) countries;

2 countries with >10%-point difference,

2 with >5% and <10% -point difference

WUENIC = not available for 2020

due to no reported coverage data for

2020

35 (18%) countries

For 2020 global and regional coverage estimates, 2019 data were imputed for 2020

for the 35 non reporting countries. These 35 countries represent 5% of the global

target population.

Rule for survey inclusion / exclusion

Final survey reports that were either publicly reported and available or those received

from countries by the WHO and UNICEF working group prior to 6 July 2021 were

included in the 2020 revision of the WUENIC, sent to countries for review and

comment. If a country replied to the draft WUENIC with information on survey

results to consider, then the survey results were included in the final report if the

survey report included a methods description in addition to the survey coverage

estimates.

.

As in the past, only surveys with final reports are considered for inclusion. The

purpose for this restriction of including survey data between the Draft and Final

estimates is to hold true to a general principle not to make changes in underlying input

data or working group decisions that the Member States have not seen. Past

experiences with coverage survey results that changed between preliminary and final

reports dictate the importance of this restriction. In addition, preliminary survey

results often present vaccination coverage estimates based on the combination of

respondent recall and documented evidence but not by documented evidence alone,

making recall bias adjustment for multidose antigens impossible. If preliminary

survey results are available, they are noted in the right-side explanatory text in the

country reports.

Countries for which new surveys were included for the 2019 WUENIC revision:

Page 8: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

8

Demographic and Health Survey (DHS)

Bangladesh 2017-18

The Gambia 2019-20

Liberia 2019-20

Senegal 2019

Sierra Leone 2019

Turkey 2018

Multiple Indicator Cluster Survey (MICS)

Central African Republic 2018-2019

Costa Rica 2018

Cuba 2019

Algeria 2019

Guinea-Bissau 2018-2019

Guyana 2019-2020

Madagascar 2018

North Macedonia 2018-2019

Nepal 2019

State of Palestine 2019-2020

Serbia 2019

Sao Tome and Principe 2019

Thailand 2019

Tonga 2019

Other coverage surveys including vaccination coverage

Routine Vaccine Coverage Survey Coupled with the November 2019 Measles and

Rubella (RR) Post-Campaign Coverage Survey in Burkina Faso

Bangladesh EPI Coverage Evaluation Survey 2019

Eritrea National EPI Coverage Survey Report, 2020

South Africa National EPI Coverage Survey Report, 2019-20

18 surveys supported reported coverage (The Gambia, Sierra Leone, Turkey, Costa

Rica ,Cuba, Algeria ,Guinea-Bissau, Guyana, North Macedonia, Nepal, State of

Palestine, Serbia, Sao Tome and Principe, Thailand, Tonga, Burkina Faso, Eritrea and

South Africa

6 survey results served as the basis for the estimates (Bangladesh (2) , Liberia,

Senegal; Central African Republic, Madagascar,

Other surveys not used to estimate but included as comments

Spain –2017-2018 serosurvey including some vaccine-preventable disease data, but

not by single age cohort

Azerbaijan – 2018 and 2019 surveys using convenience sampling

Kiribati – 2018-2019 Social Development Indicator Survey – data not available in

standard format

Mexico – ENSANUT coverage reported separately for children with documented

evidence of vaccination vs. those for whom only recall was available

Page 9: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

9

In Nigeria, the working group had been made aware of preliminary results from a

2019 National Nutrition and Health Survey using the SMART methodology. The

Government of Nigeria reported a preliminary DTP3 coverage of 67% from the

survey. Because a final report was not shared, the result was not considered for this

revision. It is important to note that experts have raised concern with the

comparability of the sampling and survey methods of recent SMART NNHS surveys

in Nigeria vis-à-vis DHS/MICS surveys; thus, even if the survey results had been

finalized, there is no guarantee that the surveys would have informed the level of

WUENIC given that the working group has recently ignored the NNHS results due to

inconsistencies with DHS/MICS in the same or neighboring cohort years.

Page 10: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

10

Figure. Years since most recent survey with vaccination coverage estimates

Additional data sources:

Estimated population data2 from the UN Population Division are used as one of the

inputs utilized in the review of country data and when the working group considers

uncertainty in the WHO and UNICEF estimates. The World Population Prospects:

2019 revision data were used for informing the WUENIC Grade of Confidence (GoC)

and producing the global and regional average coverage estimates as well as for

computing the estimated number of un- and under-immunized children.

Direct communications with country teams between WUENIC Draft and

Finalization

WHO and UNICEF encourage countries to review and comment on the country

reports shared following the Draft production. In past years, regional or sub-regional

consultations have been held during May/June to go through select country data and

estimates. During the 2020 revision due to Covid-19 disruptions, WHO and UNICEF

held conference call consultations with country teams from Haiti, Lao PDR and

Pakistan.

2 United Nations, Department of Economic and Social Affairs, Population Division (2019). World

Population Prospects 2019, Online Edition.

Page 11: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

11

Changes between 2019 and 2020 WUENIC revision:

Database structure change.

None

Changes in estimates due to updates in empirical data between revisions result

from:

• Updated data submitted by Member States and previously reported time series

were revised.

• New survey data becoming available after 2019 revision (between 29 June

2020 and 6 July 2021)

• 2019 data reported late, and not included in 2019 revision of coverage

estimates (between 29 June 2020 and 6 July June 2021)

A list of countries with major changes in the estimated time series is provided in

Table 1.

Vaccine introduction and data availability

For vaccine introduction, or the introduction of additional doses into the routine

immunization schedule (such as the second dose of measles-containing vaccines or

Hepatitis B birth dose), WHO and UNICEF estimates of national immunization

coverage are produced beginning in the first year for which data are reported by

national authorities. In situations where a vaccine was introduced sub-nationally or

the introduction occurred after January, the WHO and UNICEF estimates of coverage

are based on computed coverage for the annual national target population.

The following lists of countries reflect those where WHO is aware that the country

has introduced the vaccine but for which there is insufficient data for generating

WUENIC.

Hepatitis B

Countries with infant immunization not in national schedule

DNK;FIN;HUN;ISL;SLV

Hepatitis B birth dose:

Data collection form was modified in 2017 (for 2016 data). Countries were asked to

report birth dose given in 24 hours and “all birth doses” (i.e., within and after 24

hours). This permitted revision of historical data and exclusion of countries where

data on birth dose given within 24 hours is not available.

Angola: Introduced in 2015 no birth dose given within 24 hours reported. No data

reported for 2016 and 2017.

Australia: No data reported on birth dose given within 24 hours.

Bosnia and Herzegovina: No data reported on birth dose given within 24 hours.

Page 12: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

12

Botswana: No data reported on birth dose given within 24 hours.

Estonia: Introduced in 2003. According to the national immunization schedule HepB

first dose should be given within 12 hours of birth. National reporting system doesn`t

seem able to provide the number of hepatitis B vaccine doses given within 24 hours of

birth.

Equatorial Guinea: Introduced in December 2018; reported only very few vaccine

doses administered; no coverage reported on birth dose given within 24 hours.

Gambia: No data reported on birth dose given within 24 hours.

Libya: No birth dose given within 24 hours reported.

Mauritania: Introduced in 2013. No data reported on birth dose given within 24

hours.

Nigeria: Introduced in 2014. No data reported on birth dose given within 24 hours.

Pakistan: Introduced in 2019, not able to distinguish between doses given in 24h or

after.

Paraguay: Introduced in 2017. No data reported on birth dose given within 24 hours.

Syria: Introduced in 2003.

* Russian Federation: Does not appear that hepatitis B birth dose is recommended;

reported national schedule information notes a recommended dose of hepatitis B at

day 1, but not necessarily within the first 24 hours. Data not collected by the country.

Canada reports partial HepB birth dose, but no data are reported.

Hib

Thailand: Introduced in June 2019. No reported data.

Additional 2 countries missing introduction CHN, RUS

Pneumococcal conjugate vaccine (PcV):

.

Austria: Introduced in 2014. No reported data.

Croatia: Introduced in 2019 . No reported data.

Monaco: Introduced in 2006. No reported data.

Malta: introduced in 2020 Only 1st and 2nd dose administered during 2020.

Malaysia: Introduced in December 2020 with catch-up vaccination for children born

since January 2020. No data reported.

North Macedonia: Introduced in 2019. No reported data.

Tajikistan: Introduced in 2020, no data reported.

N.B.: Countries may use different PCV schedules, namely 3 basic doses in infants

with no booster (3+0), 2 basic doses in infants with a later booster (2+1), or 3 basic

doses in infants with a booster (3+1). Some countries have been recently changing

their recommended PCV schedule. In most countries PCV3 represents the third dose

whether given before 12 months or at or after 12 months, but in some cases coverage

estimates may reflect the percentage of surviving infants who received two doses of

PCV prior to the 1st birthday.

Page 13: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

13

Second dose measles-containing vaccine:

Ireland: Introduced since 1982; data are not reported.

Rubella-containing vaccine:

Based on Measles estimates, but modified if partial introduction.

Democratic People’s Republic of Korea: introduced in 2019. Data not reported.

Rotavirus vaccine (Rota last dose):

Albania: Started for children born from August 2019. Reported only 1st dose for that

year. No data reported for 2020.

Andorra: Introduced in 2020. No reported data.

Japan: Introduced in 2020. No reported data.

Nepal: Introduced in 2020. No reported data.

North Macedonia: Introduced in 2019. No reported data.

Russian Federation: Introduced sub-nationally in 2016. No reported data.

Thailand: Introduced sub-nationally as part of a pilot project; no estimate produced.

Timor-Leste: Introduced in 2019. No reported data.

.

IPV:

Poland: No reported data as of 2019.

Yellow Fever:

Seychelles: Uses vaccine in routine schedule, estimate not made as country is not at

risk.

Cabo Verde: Uses vaccine in routine schedule, estimate not made as country is not at

risk.

Tome and Principe: Country no longer at risk; continued using vaccine in routine

schedule; estimates provided.

Table 1: Countries with important revisions in the WHO and UNICEF estimates

of national immunization coverage (WUENIC estimates) time series between

2019 and 2020 revisions

Page 14: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

14

Table 2: List of countries where WHO and UNICEF estimates of national

immunization coverage are different from reported data — based on DTP3

coverage in 2020:

Reported data: countries official estimates are treated as reported data unless the

working group decides to accept the reported administrative coverage data instead.

Administrative coverage data are accepted if the government official data are absent

or there is insufficient justification for government official estimate or the government

official estimate represents target coverage instead of achieved coverage.

The comment field in the table below provides an explanation of 2020 coverage

estimates; for a more comprehensive explanation, it is important to look at the

explanations of the complete time-series for different antigens from the specific

country profiles: http://apps.who.int/immunization_monitoring/globalsummary/wucoveragecountrylist.html

Gavi

Eligible

Phase

WHO

region

Country Est Adm Gov Comment Diff

x EMR Afghanistan 70 85 85 Reported data calibrated to 2016 levels. Estimate challenged by: D-R-

-15

x AFR Angola 51 72 72 Reported data calibrated to 2014 levels. Country indicates that due to Covid-19 restrictions most health facilities were only partially operational between March and July 2020. Reported administrative data reflect incomplete reporting. Programme reports subnational vaccine supply disruptions for all

-21

Page 15: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

15

antigens. WHO and UNICEF recommend assessment of the routine monitoring system. WHO and UNICEF are aware of a 2021 Demographic and Health Survey and await the final results. Estimate challenged by: D-R-

x AFR Benin 72 115 71 Estimate exceptionally based on the difference between administered doses 2019 to 2020 applied to the 2019 WUENIC estimate. Reported data excluded. Inconsistent decrease in reported denominator. Official estimate not explained and inconsistent with previous years. Reported data excluded due to sudden change in coverage from 82 level to 71 percent. Programme reports a one month vaccine stock-out at national level. Estimate challenged by: D-R-

1

x SEAR Bangladesh 98 110 93 Estimate based on extrapolation from data reported by national government. Reported data excluded. Nationally reported data for official coverage includes only valid doses administered. Estimate challenged by: D-

5

AMR Brazil 77 77 86 Estimate based on administrative report. Increase in reported coverage is unexplained but may reflect recovery from vaccine stockouts reported for 2019. Reported data excluded due to sudden change in coverage from 70 level to 86 percent. A nationwide study by Silveira et al. (doi.org/10.1016/j.vaccine.2021.04.046) observed that the COVID-19 pandemic was associated with a 20 percent decrease in childhood vaccinations though much of the decline was reversed by the end of 2020. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. Estimate challenged by: R-

-9

AFR Botswana 95 77 NA Reported data calibrated to 2012 levels. Reported data excluded. Fluctuation in reported data suggest poor quality administrative recording

18

Page 16: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

16

and reporting. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. WHO and UNICEF recommend an assessment of the administrative recording and reporting system. Country switched to DHIS2 information system and indicates some unquantified data loss. Programme reported a three month vaccine stock-out at national level. GoC=Assigned by working group. Reported coverage and denominator are inconsistent, and the estimate is confirmed only by survey for 2006 and 2012 birth cohorts.

x AFR Central African Republic

42 80 80 Reported data calibrated to 2017 levels. Reported data excluded. Fluctuations in reported data suggest poor quality administrative recording and reporting. Reported data excluded due to sudden change in coverage from 61 level to 80 percent. Programme notes issues with data quality and use including that the denominators come from projections from a 2003 census. Estimate challenged by: D-R-

-38

x AFR Côte d’Ivoire 80 90 90 Reported data calibrated to 2017 levels. WHO and UNICEF are aware of a 2021 Vaccination Coverage Survey and await the results. Estimate challenged by: D-R-

-10

x AFR Cameroon 69 81 81 Reported data calibrated to 2017 levels. Programme reports of home-based records (cards) stockout of unknown duration. Programme reports six months vaccine stock-out at national level and unknown for subnational levels. Estimate challenged by: D-R-

-12

x AFR Democratic Republic of the Congo

57 95 95 Reported data calibrated to 2016 levels. Reported data excluded. Review of trends in reported coverage during 2011-2016 suggests the administrative recording and reporting system was unable to identify declines in coverage

-38

Page 17: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

17

suggested by surveys. Estimate challenged by: D-R-

x AFR Comoros 87 74 91 Estimate exceptionally based on the difference between administrative coverage 2019 to 2020 applied to the 2019 WUENIC estimate. Programme notes that reported official coverage is informed by results from a 2016 coverage survey. WHO and UNICEF recommend an assessment of the administrative data. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. Programme reports three month vaccine stock-out at national level. Estimate challenged by: D-R-

-4

AMR Costa Rica 95 97 97 Estimate based on extrapolation from data reported by national government. Reported data excluded. Data reported presents inconsistencies. Reported denominator for vaccines recommended among infants present an unexplained decline of 16 percent while numerators decline over ten percent. For vaccines recommended during the second year of life, namely MMR and PCV3, the denominator is consistent with previous years and numerators are similar to those reported for 2019. Estimates likely overestimate 2020 coverage levels. Estimate challenged by: D-

-2

x AFR Ethiopia 71 99 99 Reported data calibrated to 2017 levels. Estimate challenged by: D-R-

-28

x AFR Guinea 47 90 85 Reported data calibrated to 2016 levels. Reported data excluded. Estimates may not reflect actual changes in coverage as reported number of administered doses declined from 2019 to 2020. However, reported numerator and denominators have been inconsistent over time. Official coverage for the last three years follows an upwards trend, while administrative coverage and number of children vaccinated follows a declining trend for all vaccines recommended after birth. Estimate challenged by: D-R-

-38

Page 18: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

18

AFR Equatorial Guinea

53 65 65 Reported data calibrated to 2016 levels. Reported data excluded. Unexplained variation in reported target population as well as in reported number of children vaccinated. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. GoC=Assigned by working group. Fluctuation in reported coverage across the time series suggests challenges in routine monitoring system.

-12

x AMR Haiti 51 83 83 Reported data calibrated to 2018 levels. Reported data excluded due to sudden change in coverage from 66 level to 83 percent. Programme reports a 12 month stockout of reconstitution syringes. Estimate challenged by: D-R-

-32

x AFR Kenya 89 85 85 Estimate based on difference in administered doses reported between 2019 and 2020 applied to the 2019 estimate. Reported denominator for 2020 is from projections of the 2019 census. Declining reported denominator for the last three years. WHO and UNICEF recommend a revision of historical denominators. WHO and UNICEF are aware of an ongoing DHS survey in 2021 and await the results. Programme reports a vaccine stock-out at national and subnational levels of less than one month. Estimate challenged by: R-

4

x WPR Cambodia 92 106 106 Reported data calibrated to 2013 levels. Reported data excluded because 106 percent greater than 100 percent. WHO and UNICEF are aware of an ongoing Demographic and Health Survey and await the final results. Estimate challenged by: D-R-

-14

x WPR Lao People’s Democratic Republic

79 91 91 Reported data calibrated to 2016 levels. Estimate challenged by: R-

-12

EMR Lebanon 71 81 81 Decline in reported coverage related to COVID-19 pandemic service disruptions. Although there are challenges with the reported data,

-10

Page 19: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

19

the trend in coverage from 2019 to 2020 is reflected in the estimated coverage. Reported data excluded. Programme notes ongoing challenges with regards to accurate monitoring of the number of children vaccinated as well as the target population. Administrative data is collected from the public sector, while for private providers the numerator is estimated from vaccine purchase data. The denominator is derived from national statistical reports and UNHCR data inclusive of Lebanese and non-Lebanese children. Programme notes the absence of single year of age information for the target population, thereby requiring use of crude approximations. Reported data excluded due to sudden change in coverage from 93 level to 81 percent. The reported target population was the same for 2019 and 2020. Estimate challenged by: D-R-

x AFR Liberia 65 82 82 Reported data calibrated to 2018 levels. Programme reports a four month vaccine stockout at national and subnational levels. Estimate challenged by: D-R-S-

-17

EMR Libya 73 95 97 Prolonged instability continues. Available data to quantify the magnitude of the disruption of health service delivery are scarce. Programme reports three month vaccine stock-out at national and sub-national levels. As done for previous years, using this information and a strong assumption that immunization services have been severely disrupted during the vaccine stock-out, the estimate is based on a 25 percentage point reduction in coverage consistent with the duration of the stock-out. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage, as the situation permits. Estimate challenged by: D-R-

-24

x AFR Lesotho 87 95 95 Reported data calibrated to 2016 levels. Reported data excluded.

-8

Page 20: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

20

Fluctuations in reported data suggest poor quality administrative recording and reporting. Estimate challenged by: D-R-

x AFR Madagascar 68 93 93 Reported data calibrated to 2017 levels. WHO and UNICEF are aware of a 2021 DHS and Vaccination Coverage Survey and await the final results. Programme reports one month vaccine stock-out at national and subnational levels. Estimate challenged by: D-R-

-25

x AFR Mali 70 90 71 Estimate exceptionally based on the difference between administative coverage 2019 to 2020 applied to the 2019 WUENIC estimate. Reported data excluded. Programme reports disruptions in performance related to insecurity and reductions in attendance to vaccination sessions related to the COVID-19 pandemic, especially in urban areas. Also issues with incomplete reporting linked to problems with connectivity. WHO and UNICEF are aware of a 2021 Vaccination Coverage Survey and await the results. Estimate challenged by: D-R-

-1

x AFR Mozambique 79 108 82 Estimate exceptionally based on the difference between administrative coverage 2019 to 2020 applied to the 2019 WUENIC estimate. Reported data excluded due to sudden change in coverage from 95 level to 82 percent. WHO and UNICEF are aware of an ongoing DHS survey and await the results. Programme reports a two month vaccine stock-out at national and subnational levels. Estimate challenged by: D-R-

-3

x AFR Mauritania 71 81 97 Estimate exceptionally based on the difference between administrative coverage 2019 to 2020 applied to the 2019 WUENIC estimate. Reported data excluded. Concern remains regarding the quality of the recording and reporting system. Programme reports changes in the Ministry of Health that affected the funding and operations of the Expanded Programme on Immunization, in addition to disruptions related to

-26

Page 21: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

21

COVID-19. WHO and UNICEF are aware of ongoing DHS and await the final results. Estimate challenged by: D-R-

AFR Mauritius 93 84 95 Estimate based on difference in administrative coverage between 2019 and 2020 applied to the 2019 estimated coverage. Reported data excluded due to sudden change in coverage from 96 level to 84 percent. National estimates are adjusted to include immunizations occurring in the private sector. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. Official estimate excluded because the difference between administrative and official coverage is unexplained. Official coverage estimates present an inconsistent trend between 2019 and 2020. Estimate challenged by: R-

9

x AMR Nicaragua 92 106 106 Estimate exceptionally based on the difference between administrative coverage 2019 to 2020 applied to the 2019 WUENIC estimate. Reported data excluded because 106 percent greater than 100 percent. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. Estimate challenged by: D-R-

-14

x EMR Pakistan 77 83 80 Vaccine stock-out of unspecified duration. Estimate exceptionally based on the difference between administrative coverage 2019 to 2020 applied to the 2019 WUENIC estimate. Official estimates for 2019 and 2020 based on the results of TPVICS, a large vaccination coverage survey conducted in early 2021. Final TPVICS report not available at the time of reporting eJRF. Monthly coverage data showed a significant decline in coverage from March to May 2020 followed by increases as a result of intensive catch-up

-3

Page 22: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

22

vaccination activities. Estimate challenged by: D-R-

x WPR Papua New Guinea

39 45 45 Estimate informed by relative change in doses administered from 2018 levels to 2020. Estimate challenged by: D-R-

-6

AMR Paraguay 79 67 67 Reported data calibrated to 2015 levels. Programme reports a one month vaccine stock-out at national and subnational levels. Estimate challenged by: D-R-

12

EMR State of Palestine

99 102 NA Estimate based on extrapolation from data reported by national government. Reported data excluded because 102 percent greater than 100 percent. GoC=R+ S+ D+

-3

x AFR Senegal 91 96 96 Reported data calibrated to 2018 levels. Estimate challenged by: D-R-

-5

x EMR Somalia 42 73 73 Reported data calibrated to 2010 levels. Reported data excluded. Incomplete reporting noted by the country. WHO and UNICEF encourage periodic independent coverage assessment in addition to improving the coverage of immunization services. Programme reports a two month vaccine stock-out at national and subnational levels. Estimate challenged by: D-R-

-31

x AFR South Sudan 49 60 60 Estimate based on extrapolation from data reported by national government. Reported data excluded. Unexplained change in denominator from 2018 to 2019. Country reports that due to instability in the country, there is a large population movement in and out of the country which affects the denominator. Country also notes issues related to the accuracy of the numerator such as high turn over of vaccination staff coupled with limited capacity in tallying, recording and reporting of immunization data. WHO and UNICEF encourage continued efforts to improve recording and monitoring while the programme continues efforts to increase vaccination coverage. Estimate challenged by: D-

-11

AMR Suriname 51 65 65 Reported data calibrated to 2016 levels. WHO and UNICEF observe

-14

Page 23: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

23

that recent survey results suggest lower levels of coverage than that reported by the programme during the past 10 years. Further investigation to understand underlying differences is warranted, and WHO and UNICEF recommend a high-quality independent empirical assessment to confirm reported levels of coverage. Decline in reported coverage is unexplained by country but aligns with COVID-19 pandemic service disruptions. Estimate challenged by: R-

EMR Syrian Arab Republic

49 68 68 Reported data calibrated to 2005 levels. Reporting from some districts is incomplete. The denominator used for administrative coverage has been estimated from the coverage of the polio campaigns of 2017 in addition to vaccinated children per health facility. The last population census was conducted in 2004. The target population is estimated and likely inaccurate due to the constant movement outside and inside the country. WHO and UNICEF are aware of the coverage evaluation survey conducted 2020-2021 and await the final results. Estimate challenged by: D-R-

-19

x AFR Chad 52 83 83 Reported data calibrated to 2017 levels. Reported target population declined between 2019 and 2020. Immunization estimates from MICS survey could not be produced due to an error in data collection. WHO and UNICEF recommend a high-quality vaccination coverage survey. Programme reports district level vaccine stock-out of unspecified duration. Estimate challenged by: D-R-

-31

x AFR Togo 82 89 89 Reported data calibrated to 2016 levels. Estimate challenged by: D-R-

-7

x AFR United Republic of Tanzania

86 102 95 Reported data calibrated to 2018 levels. Estimate challenged by: D-R-

-9

AMR Saint Vincent and The Grenadines

97 106 106 Estimate based on extrapolation from data reported by national government. Reported data excluded because 106 percent greater than

-9

Page 24: WHO UNICEF Immunization Coverage Estimates 2020 revision

Document last revised: 16 July 2021

24

100 percent. Fluctuation in reported data is attributed to small birth cohort. No nationally representative household survey within the last 5 years. WHO and UNICEF recommend a high-quality survey to confirm reported levels of coverage. GoC=R+ D+

WPR Samoa 79 89 89 Reported data calibrated to 2012 levels. Preliminary 2019-2020 MICS results suggest coverage of 39 percent. This survey may have coincided with period of reduced coverage. Fluctuation in reported data is attributed to small birth cohort. Estimate challenged by: D-R-

-10

x EMR Yemen 72 87 87 Reported data calibrated to 2012 levels. Despite the ongoing humanitarian crisis, reported coverage levels generally have not declined. Government indicates that official estimates are derived from the administrative coverage and that vaccination sites continue to send monthly reports to the district. Estimate challenged by: D-R-

-15

Est - WHO UNICEF coverage estimates 2020 revision

Adm – reported administrative coverage data

Gov - reported government official estimate of coverage

Diff - difference between reported data and WHO/UNICEF coverage estimates where the reported

data reflects the government official estimate if provided, otherwise it reflects the reported

administrative coverage data unless government official estimate excluded.