The APGI (Association de Pharmacie Galénique Indus-

trielle) is organizing for the first time a workshop dedi-

cated to Oral Controlled Release Solid Dosage forms.

This includes matrix systems as well as coated dosage

forms, such as tablets, pellets and capsules.

During the one day event, oral and poster presenta-

tions from academia and industry as well as practical

demonstrations (in small groups) are foreseen.

The entire spectrum, ranging from engineering aspects

during the manufacturing process, the portfolio of com-

mercially available excipients allowing to formulate a

large variety of drugs, the underlying mass transport

mechanisms and physical principles, characterization

methods for the key properties of the devices as well

as potential pitfalls and hurdles to be overcome during

product development will be addressed.

As practical demonstrations are included, the maxi-

mum number of participants is limited to 150.

The workshop will be held at the University of Lille,

College of Pharmacy, 3 Rue du Professeur Laguesse,

59006 Lille, France..

For travel information, please visit our website:

https://www.apgi.org/workshops-ocr-ws-2017-home

Lille can be easily reached by train (TGV and Eurostar:

30 min from Brussels, 1 h from Paris, 1.2 h from Lon-

don), by plane (Lille Lesquin Airport, or Paris Charles

de Gaulle Airport – 50 min by train, or Brussels Interna-

tional Airport – 2x30 min by train) as well as by car.

Oral controlled release solid dosage forms are of great

practical importance, allowing to optimize the resulting

drug concentrations at the site of action in the human

body. Hence, the therapeutic efficacy of the drug treat-

ment can be improved, while the risk of toxic side ef-

fects be limited. In addition, the administration frequen-

cy can be reduced, leading to increased patient compli-

ance. Different types of solid oral dosage forms can be

used to accurately control the release of a drug within

the gastro intestinal tract. This includes matrix systems

and coated dosage forms (e.g. tablets, pellets and cap-

sules). However, it can be very challenging to provide

a desired release profile for a particular drug at a given

dose. Also, the variability of the environmental condi-

tions in the gastro intestinal tract, the potential ethanol-

sensitivity of dosage forms containing highly potent

drugs, as well as the risk of abuse of controlled release

dosage forms containing high amounts of opioids, are

important aspects to be considered.

This workshop will give an update on the current state of the art of how to best formulate oral controlled re-lease solid dosage forms. An overview on the

available excipients, preparation techniques and appa-ratuses, characterization methods and future strategies will be given by world-wide leading experts in the field.

Workshop on Oral Controlled Release

Thursday 6 July 2017, Lille, France

APGI International Society of Drug Delivery Sciences and Technology

For further information:

APGI

5 Rue Jean Baptiste Clément

92290 Châtenay-Malabry, France

Tel: +33-6-29366739

apgi.asso@u-psud.fr

Silver sponsor

-

Platinum sponsors

Workshop on Oral Controlled Release

Thursday 6 July 2017, Lille, France

APGI International Society of Drug Delivery Sciences and Technology

Programme

8:45 - 8:50 Welcome

8:50 - 9:15 Prof. Juergen Siepmann, University of Lille

Solid oral controlled release dosage forms: Drug release mechanisms and mathematical modeling

9:15 - 9:40 Prof. Jennifer Dressman, University of Frankfurt

Applications of biorelevant media in drug development

9:40 - 10:05 Dr. Thorsten Cech, BASF

Avoiding Alcohol-Induced Dose Dumping: Formulation strategies based on poly(vinyl acetate)

10:05 - 10:30 Dr. Klaus Wening, Gruenenthal

Abuse deterrent formulations – Needs, development strategies and technology landscape

10:30 - 11:00 Coffee break

11:00 - 11:25 Prof. Roland Bodmeier, Freie Universitaet Berlin

Oral controlled release formulation strategies for high dose drugs and water-insoluble drugs

11:25 - 11:50 Dr. Miriam Robota, Evonik

Customized release profiles using EUDRAGIT® polymers

11:50 - 12:15 Prof. Thomas Rades, University of Copenhagen

Advanced characterization techniques for solid dosage forms

12:15 - 14:00 Lunch

14:00 - 16:00

Practical demonstrations (in small groups)

16:00 - 16:30 Coffee break

16:30 - 16:55 Prof. Thomas De Beer, University of Ghent

PAT for process monitoring and control of continuous tablet manufacturing processes

16:55 - 17:20 Dr. Ali Rajabi-Siahboomi (replaced by Paul Smith), Colorcon

Patient & manufacturer centric development of controlled release matrices

17:20 - 17:45 Dr. Jonathan Goole, Free University of Brussels

Oral modified-release drug delivery system based on multilayered microparticles in a liquid dosage form

17:45 - 17:50 Closing

Exhibitors: BASF, Biogrund, Colorcon, Evonik, Freund -Vector/Pharmtec, Gamlen Tableting, Medelpharm,

Pharma Test, ProCepT, Shin-Etsu, Sirius Analytical, Sotax, Thermo Fisher Scientific

Before 15 April, 2017 After 15 April, 2017

APGI-Member 500 € + VAT 600 € + VAT

Non-Member 600 € + VAT * 700 € + VAT *

Registrations fees

* including APGI membership fee for 2017

Institutional partners

Visit our website: https://www.apgi.org/workshops-ocr-ws-2017-home

R&D tablet coating (ProCepT)

Compression coating (Medelpharm)

Compression (Gamlen Tableting)

Hot melt extrusion (Thermo Fisher Scientific)

UV-imaging (Sirius Analytical)

Dissolution testing (Sotax)