active ingredients selector book 2010 ingredients/library/1mib_soc… · cell renewal specific...

Active ingredients selector book 2010

Inspired by nature – Realized by science Mibelle Biochemistry designs and develops innovative, high-quality actives based on naturally derived compounds and profound scientific know-how.

Anti-aging Skin rejuvenation 04Photo-aging/Sun care 06Experts 08Antioxidant/Energizing 10

Hydration/Soothing 12

Active protection 14

Whitening 16

Hair 18

Anti-cellulite/Slimming 20

Natural Cosmetics 22

Carrier system = Liposome, = Double vector system, = Nano-Emulsion, = Double Nano-Emulsion Preservative PE = Phenoxyethanol, * = 2 versions are available

04

Name Characteristics

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PhytoCellTec™ Malus Domestica

Plant stem cells for skin stem cells protection

• Protection of cell longevity

• Plant cell culture technology

• Delaying chronological aging

• Real rejuvenation• Revolutionary

anti-aging products• Cosmeceuticals

Swiss apple stem cells PE/Sodium ben zoate*

Happybelle-PE

Phyto-Endorphins in a double vector system

• Well-being• Radiance• Collagen booster• “Neuro-cosmetics”

• SPA treatments• “Happy skin” products

• Monk‘s pepper berries extract (phyto-endorphins)

• Vitamins C and E

Perfection Peptide P3

Biomimetic peeling to create a perfect skin

• Luminosity• Even complexion• Cell renewal

• Cosmeceuticals• Daily peeling• “Radiance” care

Tripeptide (Hexanoyl-Arg-Ala- Nle-NH2 Acetate Salt)

PE/no*

Activity Improvement of skin quality and radiance

Anti-aging Skin rejuvenation

Proven efficacy in vitro test clinical study

05

Proven efficacy Benefits

Stim

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es

colla

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Ant

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s fir

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Imp

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s hy

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Spec

ific

tes

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Use

leve

l in

%

Clin

ical

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test

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Eff

ect

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af

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1 m

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• Up-regulates specific genes involved in delay of senescence, anti-oxidation and DNA damage correction

• Maintains the vitality of epidermal stem cells

2.0 – 5.0

Increases the feeling of well-being (consumer test)

1.0 – 2.0

• Increases the turn-over of stratum corneum

• Smoothes the skin micro-relief (laser profilometry)

• Improves the skin cohesion (scanning electron microscopy)

0.5 – 3.0


Anti-aging Photo-aging/Sun careActivity Prevent photo-aging, protect the skin against UV damage

06


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PhytoCellTec™ Solar Vitis

Protects epidermal stem cells against UV damage

• Protection of essential cells

• Plant cell culture technology

• Smart sun care• “Advanced” stem cell

cosmetics

Grape stem cells Sodium benzoate

GSP-T More than an antioxidant • Broad protection against daily oxidative stress

• Stable combination of water- and oil-soluble antioxidants

• Cosmeceuticals• Sensitive skin• UV tolerance enhancer

• Swiss grape seed extract (procyanidins)

• Natural vitamin E

Helioguard 365

Natural UVA-screening active to protect against photo-aging

• Daily UVA-protection• DNA protection

• Face care• Foundation

Mycosporine-like amino acids (MAA)

PE

CM-GlucanGranulate

The repair and defense molecule

• Protection• Regeneration

• Skin repairing• Sensitive skin• Skin defense enhancer

Sodium carboxymethyl beta-glucan from baker’s yeast

no/PE*

AquaCacteen Soothes and hydrates women and men’s skin

• Calming• Skin resistance booster• Active for men

• Sensitive skin• Baby care

Organic opuntia ficus-indica stem extract

PE/no*


07


Inhi

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s lip

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Ant

i-irr

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acti

vity

Inhi

bit

s

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of

skin

lip

ids

Ant

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nkle

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Imp

rove

s fir

mne

ss

des

pit

e U

V

rad

iati

on

Imp

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• Maintains the vitality of epidermal stem cells

• Protects epidermal stem cells against UV stress

0.4 – 1.0

• Decreases the toxicity of oxidized squalene on cells

• Decreases UV-induced redness

0.5 – 2.5

• Reduces UV-induced DNA damage• Boosts SPF• Improves smoothness

1.0 – 5.0

Improves cell renewal 0.02 – 0.1

Reduces redness 0.5 – 2.0


08


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Lipobelle Soyaglycone

Lift it up! • Density• Anti-gravity• Lifting effect• Collagen booster

• Re-plumping• Multi-dimensional

anti-aging

Soy isoflavone aglycone (genistein)

MAXnolia Fights skin inflamm’aging

Protection against chronic inflammation

• Eye contour formulations

• Skin prone to redness

Magnolia officinalis bark extract

Ameliox To fade away expression lines

• Wrinkle reduction• Immediate smoothing

• Cosmeceuticals• Anti-glycation

• Carnosine• Silymarin• Natural vitamin E

PE/no*

AstraForce Anti-aging especially for blemished skin

• Both anti-blemishes and anti-aging

• Clarity

• City products• Skin texture enhancers• Combination/oily skin

Astragalus membranaceus root extract

PE

Activity Focus on a specific corrective action

Anti-aging Experts


09


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• Genistein stimulates collagen IV production

• The liposomal form increases the skin penetration of genistein

• Diminishes skin laxness and ptosis• Makes the skin appear 5 years

younger

1.0 – 5.0

• Reduces redness on the face• Decreases TEWL• Improves elasticity on the crow’s

feet

0.1 – 0.5

• Reduces wrinkles both on crow’s feet and forehead

• Visibly reduces lines and wrinkles (consumer test)

1.0 – 5.0

• Inhibits lipase activity• Reduces blemished skin signs

0.5 – 2.0


10


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GSP-T More than an antioxidant • Broad protection against daily oxidative stress


• Cosmeceuticals• Protection

against UV damage



NanoVit nc/oA

Bioactive phyto-omegas 3,6,9 + 7

Healthier-looking skin • Cell regeneration• Pre/after sun products

• Sea buckthorn pulp oil• Natural vitamin E

Sodium benzoate /no*

Nano- Lipobelle DN CoQ10 oA

Supersaturated CoQ10 double nano-emulsion

• Vitality• Collagen booster• Mitochondrial cosmetics

• Metabolic activation• Photo-aging prevention

• Coenzyme Q10 7 %• Natural vitamin E 0.4 %• Vitamin C 0.2 %

Benzoic acid

Nano- Lipobelle H-AECL

The power snack for skin • Nutrition• Strengthening

of skin barrier

Sensitive skin • Vitamins (A, E, C) – ester form

• Borage oil (rich in gamma linoleic acid)

NanoMax High performing antioxidant blend

Antioxidant shield • City products• Daily care

• Coenzyme Q10 0.5 % • Natural vitamin E 1 % • Vitamin C 1 %

Anti-aging Antioxidant/EnergizingActivity Revitalizing and nourishing


11


Stim

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Inhi

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Incr

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100

% n

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• Cumulative antioxidant activity• Inhibits the glycation process• Inhibits the COX-1 and COX-2

activity• Immediate anti-redness effect

0.5 – 2.5

1.0 – 5.0

Protects mitochondrial DNA 1.0 – 5.0

1.0 – 5.0

1.0 – 5.0


Hydration/SoothingActivity Promote the homeostasis of the skin and bring comfort

12


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AquaCacteen Soothes and hydrates women and men’s skin

• Calming• Skin resistance booster• Active for men

• Sensitive skin• After-shave products• Baby care

Organic opuntia ficus-indica stem extract

PE/no*

Trimoist KMF 24h hydration and protection

• 3-step moisturizer• Anti-aging

• Sensitive skin • Repair products• Body care

• CM-Glucan Granulate• Lamellar lipids• Humectants• Carnosine

NanoCacao Deep comfort and relaxation

• Relaxation• Good feeling• Oil-soluble active

• Anti-stress formulations• Color cosmetics• Wellness/SPA products

Cocoa bean lipophilic extract

PE/no*

Lipobelle Glacier

24h refreshing hydration with Swiss glacier water

• Refreshment• Long-lasting hydration

• Splashes• SPA treatments• Men‘s care

Swiss glacier water *

Poly-Fructol Adds value to all bath and hair products

• Instant hydration• Soft and fresh skin/hair

• Body care • Hair care/styling

Polymer of fructose (inulin)

PE

Femitim Especially for feminine hygiene

• Gentleness• Well-feeling

• Intimate hygiene• Wipes products

Monk‘s pepper berries extract (phyto-endorphins)


13


Ant

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Imp

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Red

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Imp

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Imp

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Spec

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Use

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%

Test

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off

ap

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Soothes men skin after shaving 0.5 – 2.0

• Protects against detergents• Increases well-being and skin

smoothness (consumer test)

1.0 – 5.0

Slows down muscle contraction (reversible effect)

3.0 – 5.0

• Protects cells against heat stress• Gives a refreshing feeling

(consumer test)

1.0 – 5.0

0.1 – 5.0

Increases well-being feeling (consumer test)

0.5 – 3.0



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Detoxophane Activates the skin’s detoxification system

• Protection against pollutants

• Photo-aging prevention

• City products• Protection against

environmental stress• Foundation

Swiss garden cress sprout extract (sulforaphane)

PE/no*

MelanoBronze Natural tanning activator Enhancement of natural skin tone

• Pre-sun care• Sun studio products • Suntan booster

• Monk‘s pepper berries extract (phyto-endorphins)

• Acetyl tyrosine

CM-Glucan Granulate

The repair and defense molecule

• Protection• Regeneration

• Skin repairing• Sensitive skin• Skin defense enhancer

Sodium carboxymethyl beta-glucan from baker’s yeast

no/PE*

EpiCalmin TCM

Superdefense by Traditional Chinese Medicine

• Skin self-protection booster

• Both soothing and anti-aging

• Sensitive skin• Wellness/SPA products• TCM cosmetics

• Lonicera japonica flower extract

• Xanthium sibiricum fruit extract

• Cyperus rotundus root extract

Sodium benzoate

Activity Boost the skin’s self defense

Active protection 14



Inhi

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Ant

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Imp

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• Protects against strong oxidizing components

• Stimulates the expression of natural antioxidants

0.5 – 3.0

• Stimulates melanin synthesis • Increases skin tanning with and

without sun

1.0 – 5.0

• Soothing activity• Limits TEWL conse cutive

to intense stress

0.02 – 0.1

• Stimulates the skin’s defense mechanisms against oxidative stress, inflammation and collagen degradation

• Reduces redness

2.0 – 5.0

15



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SulforaWhite Phyto agent for visible whitening

• Exceptional brightening benefits

• Natural whitening active ingredient

• Anti-aging with pigment disorder correction

• Whitening treatments

Swiss organic garden cress sprout extract (sulforaphane)

PE/no*

Delentigo™ The age spot solution • Prevention and treatment of age spots

• Targeted whitening effect (lightens only pigmented areas)

• Evens skin tone

• Anti-aging with age spot correction

• Hand care products• Skin luminosity

• Swiss organic garden cress sprout extract (sulforaphane)

• Soy isoflavone aglycone (genistein)

PE

NanoWhite Triple activity for skin brightening

• Even complexion• Complete action on

tyrosinase inhibition

Lightening for every day • Natural arbutin• Glutathione• Vitamin C

WhiteningActivity Skin lightening

16



Inhi

bit

s

mel

anin

sy

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Inhi

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a-M

SH

acti

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Prot

ects

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co

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Lig

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s

the

skin

Dep

igm

ents

ag

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ots

Spec

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Eff

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1 m

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• Inhibits the proteasome activity • Efficient on both Caucasian and

Asian skin type

2.0 – 5.0

• Inhibits the proteasome activity• Genistein stimulates collagen IV

production• Depigments selectively age spots

without fading the neighboring normally pigmented area

• Lifts, firms, smoothes, hydrates the skin

4.0 – 6.0

Inhibits tyrosinase activity and activation

2.0 – 5.0

17



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GSP-T Grape seed polyphenols for maximum hair protection

• Powerful radical scavenger


• Color protection

• All hair care products• Outdoor formulations• Anti-pollution hair care• Protection against

treatments



Nano- Lipobelle t-UV

Cationic nano-emulsion of UV-filters

• Protection against daily environmental stress

• Sun protection

• Sun protection• “Coloured hair”

products

UVA and UVB filters

Nano- Lipobelle DN CoQ10 oA

Hair growth with proven efficacy

• Hair growth stimulation• Strength and vitality• Anti-aging for scalp

and hair

• Metabolic activation• SPA treatments• Anti-aging products

• Coenzyme Q10• Natural vitamin E• Vitamin C

Benzoic acid

Lipobelle S100/PA

Cationic liposomal panthenol for hydration

• Repair• Hair shine• Makes combing easier

• Repair• Daily shampoos,

conditioners, sprays

D-panthenol

Activity Actives which protect, take care and beautify hair

Hair 18



Incr

ease

s p

rolif

erat

ion

of

hum

an

folli

cle

der

mal

p

apill

a

Stim

ulat

es

hair

gro

wth

Inhi

bit

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id-

per

oxi

dat

ion

Red

uces

co

lour

ed h

air

fad

ing

Soo

thin

gef

fect

Spec

ific

tes

ts

Use

leve

l in

%

Suit

able

fo

r ri

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off

p

rod

ucts

Tran

spar

ent

asp

ect

Pre

serv

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• Protects hair proteins against detergents, UV, hair-dryer and sea water

• Improves the adsorption of tocopherol on hair

• Protective effect in both leave-on and rinse-off application

0.5 – 2.5

Increases the delivery of UV filters 1.0 – 5.0

Protects mitochondrial DNA 1.0 – 5.0

0.2 – 2.0

19



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AmaraShape High performance in body shaping

• Body contouring• Thermogenic activity• Lipolytic activity

• Fitness body care• Re-sculpting body care• SPA treatments

• Caffeine• Bitter orange extract

(synephrine)

PE/no*

Iso-Slim Complex

Pro slimming – anti cellulite

• Anti-orange peel• Multi-targeted

slimming activity• Lipid breakdown

trigger

• SPA treatments• Refining skin body care• Anti-aging

• Soy isoflavone aglycone (genistein)

• Caffeine• Carnitine• Spirulina platensis

algae extract

PE/no*

Activity Slimming, firming and re-shaping

Anti-cellulite/Slimming 20



Imp

rove

s fi

rmne

ss

Imp

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s sm

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Spec

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Use

leve

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%

Eff

ecti

ve a

fter

o

nly

6 w

eeks

Pre

serv

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e-fr

ee

Abdominal girth reduction: – 2.5 cm 1.0 – 3.0

• Genistein inhibits the adipogenesis process

• Genistein stimulates collagen IV production

• Degree of cellulite: – 37 % (clinical score)

• Thigh girth: – 3.8 cm• Elasticity: +57 %

1.0 – 5.0

21

Carrier system = Liposome, = Double vector system, = Nano-Emulsion, = Double Nano-Emulsion Preservative PE = Phenoxyethanol, * = 2 versions are available, ** = Total of natural origin: chemically + physically processed natural origin ingredients, *** = Raw material certified by Ecocert Greenlife according to the Ecocert Standard for Natural and Organic Cosmetics available at www.ecocert.com/cosmetics

22

Activity Active ingredients complying with Ecocert

Natural cosmetics


Act

ive

in

gre

die

nt

Def

init

ion

Cat

ego

ry

Pre

serv

ativ

e

AquaCacteen nc Soothes and hydrates women and men’s care Hydration/Soothing no

EpiCalmin TCM Superdefense by Traditional Chinese Medicine Hydration/Soothing Sodium benzoate

NanoVit nc Bioactive phyto-omegas 3,6,9+7 Antioxidant/Energizing no

NanoVit oA Bioactive phyto-omegas 3,6,9+7 Antioxidant/Energizing Sodium benzoate

Lipobelle Glacier 24h refreshing hydration with Swiss glacier water Hydration/Soothing no

Noriguard nc Natural UVA-screening active to protect against photo-aging Anti-aging/Sun care Sodium benzoate

Femitim Especially for feminine hygiene Hydration/Soothing no


23

Proven efficacy Ecocert information

In v

itro

tes

t

Clin

ical

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dy

Use

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%

Eco

cert

ap

pro

ved

Eco

cert

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rtif

ied

***

Tota

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in**

%

Pla

nt %

Org

anic

%

Synt

heti

c %

Pre

serv

ativ

e-fr

ee

0.5 – 2 99.84 99.84 0.16

2 – 5 99.70 24 0.30

1 – 5 100 15

1 – 5 99.95 15 0.05

1 – 5 99.94 6 0.06

2 –10 99.70 0.30

0.5 – 3 100 7.23

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The information contained in this publication is provided in good faith and is based on our current knowledge. No legally binding promise or warranty regarding the suitability of our products for any specific use is made. Claim ideas are offered solely for your consideration, investigation and verification. Mibelle Biochemistry will not assume any expressed or implied liability in connection with any use of this information.

active ingredients selector book 2010 ingredients/library/1mib_soc… · cell renewal specific...

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