c a pr de pro che b scie · pr che nationa c ofes mic l section urri sion al a culu de nd b m fo...

PrChe

Nationa

Crofesemic

al section

Currissioncal a

n

iculun Dend B

um foegreeBiote

or the Proechn

he Aogranical

AcadeammScie

emyme inence

y

Curriculum for the Academy Profession Degree Programme in Chemical and Biotechnical Science – National section

University College Nordjylland 0/23

Table of contents

1. Curriculum framework .............................................................................................................. 2

1.1 Introduction ...................................................................................................................................... 2

1.2 Study programme and title ............................................................................................................... 2

1.3 Objective ........................................................................................................................................... 2

1.4 Weight ............................................................................................................................................... 2

1.5 Laws and ministerial orders .............................................................................................................. 3

2. Admission to the study programme .......................................................................................... 3

2.1 Programme requirements and/or distribution of subjects as well as entrance exam, if any ........... 3

3. The learning outcomes specified for the study programme ....................................................... 4

4. Programme structure ................................................................................................................ 5

5. Core areas of study ................................................................................................................... 5

5.1 Contents and learning outcomes for Laboratory technique and understanding .............................. 6

5.1.1 Learning outcomes ............................................................................................................. 6

5.2 Contents and learning outcomes for Biotechnology ......................................................................... 7

5.2.1 Contents .............................................................................................................................. 7


5.3 Contents and learning outcomes for Chemical technology .............................................................. 8


6. Compulsory educational components ....................................................................................... 9

6.1 Contents and learning outcomes for Chemistry and biochemistry .................................................. 9


6.2 Contents and learning outcomes for Laboratory technique and calculations ................................ 10

6.2.1 Learning outcomes ........................................................................................................... 10

6.3 Contents and learning outcomes for Quality assurance, communication and work

environment .................................................................................................................................... 11


6.4 Contents and learning outcomes for Microbiology ........................................................................ 13


6.5 Contents and learning outcomes for Fermentation, protein purification and characterisation

as well as immunochemistry ........................................................................................................... 14


6.6 Contents and learning outcomes for Spectrophotometric and potentiometric methods .............. 15


6.7 Contents and learning outcomes for Chromatographic methods .................................................. 15


6.8 Contents and learning outcomes for Biotechnological laboratory methodology and advanced

techniques ....................................................................................................................................... 16


6.9 Contents and learning outcomes for Chemical technology laboratory methodology and

advanced techniques ...................................................................................................................... 17




6.10 Number of examinations in the compulsory educational components .......................................... 18

7. Internship ............................................................................................................................... 19

7.1 Learning outcomes for Workplace organisation and culture .......................................................... 19

7.2 Learning outcomes for Safety work/work environment ................................................................. 20

7.3 Learning outcomes for Quality systems .......................................................................................... 20

7.4 Learning outcomes for Laboratory‐technical methods ................................................................... 21

7.5 Number of internship exams ........................................................................................................... 21

8. Final exam project .................................................................................................................. 21

9. Credit transfer ........................................................................................................................ 21



1. Curriculum framework

1.1 Introduction

This Curriculum applies to all provisions of academy profession degree programmes within the

chemical and biotechnical science area (AP graduate in chemical and biotechnical science). It lays

down the rules and learning outcomes that are common to all programmes and has been adopted

by the network of approved providers of the programme on 20 June 2014. This Curriculum enters

into force at the start of the study year 2014/2015. The rules and learning outcomes that only apply

to the individual institutions are described in the institutional sections of this Curriculum.

Participant institutions:

Copenhagen Business Academy

Business Academy Midtvest

Zealand Institute of Business and Technology

Business Academy Southwest

Business Academy Aarhus

Lillebaelt Academy of Professional Higher Education

Metropolitan University College

University College of Northern Denmark

1.2 Study programme and title

The name of the study programme is "Erhvervsakademiuddannelse inden for laboratorieområdet".

In English it is called the Academy Profession Degree Programme in Chemical and Biotechnical Sci‐

ence.

Students who complete and pass the programme are entitled to use the title "Laborant AK". The

English title is AP Graduate in Chemical and Biotechnical Science.

1.3 Objective

Cf. Ministerial Order no. 976 of 19 October 2009, the objective of the study programme is to qualify

the students to plan and solve tasks of a technical, discipline‐specific nature within the laboratory

area in connection with production, development, advice and control in the technical laboratories of

private and public enterprises.

1.4 Weight

The programme, which is an academy profession degree programme (full‐time study), is worth 150

ECTS credits. 60 ECTS credits correspond to the work of a full‐time student in one year.



The level of the programme in the qualifications framework: Short higher education.

1.5 Laws and ministerial orders

The following is the regulatory basis for this programme:

Consolidated Act no. 467 of 8 May 2013 on Academy Profession Degree Programmes and Pro‐

fessional Bachelor Programmes

Ministerial Order no. 1521 of 16 December 2013 on Academy Profession Programmes and Pro‐

fessional Bachelor Programmes (the Programme Order)

Ministerial Order no. 976 of 19 October 2009 on Academy Profession Degree Programmes in

Chemical and Biotechnical Science (AP Graduate in Chemical and Biotechnical Science)

Ministerial Order no. 223 of 11 March 2014 on Admission to and Enrolment on Academy Profes‐

sion and Professional Bachelor Programmes (the Admission Order)

Ministerial Order no. 1519 of 16 December 2013 on Examinations on Professionally Oriented

Higher Education Programmes (the Exam Order)

Ministerial Order no. 262 of 20 March 2007 on the Grading Scale and Other Forms of Assess‐

ment

Ministerial order no. 570 of 27 May 2010 on the Amendment of Ministerial Order on Academy

Profession Degree Programmes in Chemical and Biotechnical Science (AP Graduate in Chemical

and Biotechnical Science)

The ministerial orders are found at www.retsinformation.dk (in Danish).

2. Admission to the study programme

2.1 Programme requirements and/or distribution of subjects as well as entrance exam, if any

Students are admitted to the programme according the Admission Order.

Admission with an upper‐secondary education:

Specific admission requirements: Mathematics at level C and either biotechnology at level A or

chemistry at level C

Admission with vocational education and training (VET):

Dairyman (step 2)

Process operator (step 2)

Specific admission requirements: Mathematics at level C and either chemistry at level C or science

at level C



Other admission:

Qualifying exam for the engineering programmes

Specific admission requirements: Mathematics at level C and either biotechnology at level A or

chemistry at level C

3. The learning outcomes specified for the study programme

The goals for learning outcomes comprise the skills and competences that a chemical and biotech‐

nical science graduate must achieve during the programme, cf. the Programme Order.

Knowledge

The students should have acquired knowledge about

the general working principles in the laboratory and the principles of a good work environment

and environmentally secure handling of chemicals and products;

chemistry and biochemistry in relation to use in the laboratory;

measuring principles, function and structure of analytical equipment in relation to ordinary

use, maintenance and error detection;

the structure, pathogenicity and function of microorganisms in natural and man‐made envi‐

ronments;

the structure and function of genes;

proteins related to laboratory work, including in particular enzymes and immunoglobulines;

the principles of laboratory work documentation as well as quality assurance in the laboratory

area; and

workplace organisation, forms of collaboration and interaction with the surrounding world.

Skills

The students should be able to

select and use basic laboratory unit operations and analysis methods;

choose, operate, control and maintain common laboratory equipment and make basic error

detection;

select and use relevant laboratory methods and techniques;

prepare and implement simple chemical syntheses and characterise the products as well as as‐

sess the results;



make laboratory calculations and use statistical methods in assessing results;

use Danish and English instructions, directions and manuals;

use IT for laboratory work and reporting;

communicate results and issues from the laboratory to colleagues and other collaboration

partners; and

make simple method development and method validation, assess laboratory observations and

document their own work in accordance with current quality assurance rules.

Competences


plan, execute and document laboratory jobs, including suggest changes, make optimisations

and locate errors;

handle laboratory work in a sound manner regarding safety, health and environment;

collaborate in a discipline‐specific and interdisciplinary way, including take part in work con‐

texts in which research is conducted; and

acquire new knowledge, skills and competencies in a structured context in relation to the la‐

boratory area.

4. Programme structure

The programme is made up of two kinds of educational components:

Compulsory educational components that relate directly to the core areas stated in the Pro‐

gramme Order. The learning outcomes for compulsory educational components are common

to all provisions of the programme and are described in the national section of this Curriculum

Elective educational components that relate broadly to the core areas. The individual institu‐

tion decides the title, learning outcomes and contents of the elective educational components.

These components are described by the individual institution in the institutional sections of

this Curriculum.

The programme includes internship and a final exam project as well.

5. Core areas of study

The study programme covers the following core areas of study

1. Laboratory technique and understanding (30 ECTS)

2. Biotechnology (25 ECTS)



3. Chemical technology (25 ECTS)

A total of 80 ECTS credits

5.1 Contents and learning outcomes for Laboratory technique and understanding

Contents

The Laboratory technique and understanding core area consists of the following educational com‐

ponents:

Chemistry and biochemistry

Laboratory technique and calculations

Quality assurance, communication and work environment

5.1.1 Learning outcomes

Knowledge and understanding


and understanding of the general working techniques in the laboratory;

the principles of maintaining a good work environment;

the principles of environmentally sound handling of chemicals and products;

chemistry and biochemistry in relation to use in the laboratory;

measuring principles, function and structure of analytical equipment in relation to ordinary use;

quality assurance in the laboratory area; and

different collaboration forms.

Skills


select and use basic laboratory unit operations and analysis methods;

choose, operate and control basic laboratory equipment;

prepare and implement simple chemical syntheses and characterise the products as well as as‐

sess the results;

make laboratory calculations and use statistical methods in assessing results;



use Danish and English instructions, directions and manuals; and

use IT for laboratory equipment, data processing and reporting.

Competences


plan and carry out basic laboratory work in a sound manner regarding safety, health and envi‐

ronment;

document and present own work in respect of current quality assurance rules;

choose statistical methods in assessing results; and

take part in collaboration with students at a similar educational level.

5.2 Contents and learning outcomes for Biotechnology

5.2.1 Contents

The Biotechnology core area consists of the following educational components:

Microbiology

Fermentation, protein purification and characterisation as well as immunochemistry

Molecular‐biology techniques, cell culture and method optimisation




microbiological processes and methods;

biotechnological and molecular‐biology methods; and

legislation within microbiology and biotechnology work.

Skills


select and use basic microbiological techniques;

use biotechnological and molecular‐biology techniques;

carry out method optimisation of selected biotechnological techniques;



quality assure and assess microbiological and biotechnological analysis results; and

plan own work in the long term.

Competences


plan, quality assure and carry out tasks safely in the microbiological and biotechnological labora‐

tory; and

document, assess and communicate results in the microbiological and biotechnological labora‐

tory.

5.3 Contents and learning outcomes for Chemical technology

Contents

The Chemical technology core area consists of the following educational components:

Spectrophotometric and potentiometric methods

Chromoatographic methods

Laboratory methodology and advanced techniques




methods and techniques in chemical analyses; and

quality assurance of equipment, methods and results in the chemical laboratory.

Skills


select and use basic analysis equipment;

make chemical analyses;

quality assure and assess chemical analysis results;

make method optimisation and method validation; and

plan own work in the long term.



Competences


plan, quality assure and carry out tasks safely in the chemical laboratory; and

document, assess and communicate results in the chemical laboratory.

6. Compulsory educational components

The programme's compulsory educational components are:

1. Chemistry and biochemistry (10 ECTS)

2. Laboratory technique and calculations (10 ETCS)

3. Quality assurance, communication and work environment (10 ETCS)

4. Microbiology (5 ECTS)

5. Fermentation, protein purification and characterisation as well as immunochemistry (10 ECTS)

6. Spectrophotometric and potentiometric methods (5 ECTS)

7. Chromoatographic methods (10 ECTS)

8. Biotechnological laboratory methodology and advanced techniques (10 ECTS)

9. Chemical technology laboratory methodology and advanced techniques (10 ECTS)

A total of 80 ECTS credits

6.1 Contents and learning outcomes for Chemistry and biochemistry

Contents

Salts and molecules, intermolecular forces and polarity, states and state transitions, types of re‐

action, equilibriums, solubility, pH calculations, chemical unit operations

Hydrocarbons; halogen, hydroxyl and amino substitutes of hydrocarbons; oxo compounds; car‐

boxylic acid and their derivatives; lipids; carbohydrates; amino acids and peptides.



The students should have acquired basic knowledge about

chemistry and chemical reactions in relation to the use of substances in the laboratory; and



biochemistry and biochemical reactions in relation to use in the laboratory.

Skills


prepare and balance chemical equations;

use basic knowledge of substances in connection with production of substrates and reagents;

and

use basic knowledge of substances in relation to analysis principles.

Competences


acquire knowledge and skills within chemical technology and biotechnology.

6.2 Contents and learning outcomes for Laboratory technique and calculations

Contents

Sterilisation and disinfection, aseptic working procedures, substrate production, cultivation,

pure cultivation and counting of microorganisms as well as microscopy

The SI system, units, atom and molar mass, stoichiometric calculations, significant digits

Acid‐base, precipitation, redox and complexometric titration; purity determination; tube manu‐

facturing, dilutions; and synthesis technique and calculations

Use of weights and volumetric equipment, basic methods for characterisation of pure substanc‐

es and solutions, pH and potentiometric determination




and understanding of the general working techniques in the laboratory, including care, homo‐

geneity, objectivity and basic safety;

the basic techniques in the laboratory, including sample treatment, aseptic techniques, tube

and substrate production as well as use of common laboratory equipment; and

measuring principles, function and structure of analytical equipment in relation to ordinary use.



Skills


choose and operate basic laboratory equipment;

produce reagents and substrates;

select and use basic laboratory unit operations and analysis methods in the microbiological as

well as the chemical laboratory;

use laboratory calculations in connection with production of substrates and reagents as well as

processing of results;

use different unit operations to conduct simple chemical syntheses and purifications;

characterise synthesis products and assess the results of chemical syntheses;

use Danish and English instructions, directions and manuals.

Competences


plan and carry out basic tasks safely in the chemical and microbiological laboratory; and

make calculations of basic tasks in the chemical and microbiological laboratory.

6.3 Contents and learning outcomes for Quality assurance, communication and work environment

Contents

Introduction to international standards, quality assurance of analysis results, traceability and

control charts

Laboratory‐relevant statistics, normal distribution, confidence interval and tests on one or more

variables

Use of spreadsheet functions and graphs

General safety rules in the laboratory, laboratory safety equipment and personal protective gear,

first aid, classification and labelling of substances and products, waste handling, the working en‐

vironment act and workplace instructions

Preparation of laboratory records and reports, project and group work, literature search and

technical English






and understanding of the principles of a good work environment and of environmentally sound

handling of substances and products;

and understanding of the principles of laboratory work documentation;

current quality assurance rules;

statistics and simple statistical methods; and

different collaboration forms.

Skills


classify and label laboratory reagents according to current rules;

undertake waste handling according to current rules;

quality assure analysis results with adequate documentation and control;

control basic laboratory equipment;

apply statistics, statistical methods and simple tests in assessing results;

report on laboratory results;

use IT in connection with the use of laboratory equipment, data processing and reporting; and

take part in collaboration.

Competences


document their own work according to current quality assurance rules;

present own data and take part in a discussion of this data; and

plan and carry out laboratory work in a sound manner regarding safety, health and environment.



6.4 Contents and learning outcomes for Microbiology

Contents

Eukaryote and prokaryote cells, nutrition and metabolism as well as growth

Systematic bacteriology, fungus and virus, bacteria occurrence, significance and use as well as

growth and identification principles

Standard specifications, statistics, risk assessment, quality assurance of microbiological work




work and safety in the microbiological laboratory;

the structure, metabolism, growth conditions and significance of microorganisms;

the systematism of bacteria and fungus;

the prevalence and significance of pathogenic microorganisms;

substrate principles; and

the use of rapid procedures.

Skills


select and use microbiological cultivation techniques for detection and identification of micro‐

organisms;

carry out microbiological analyses according to standard specifications; and

quality assure and assess microbiological analysis results.

Competences


plan, quality assure and carry out tasks safely in the microbiological laboratory; and

document, assess and disseminate results in the microbiological laboratory.



6.5 Contents and learning outcomes for Fermentation, protein purification and characterisation as well as immunochemistry

Contents

Propagation, fermentation types and equipment as well as product isolation

The structure, function and determination of proteins

Enzyme catalysis, activity, kinetics, inhibition and assays

Methods for protein purification and characterisation of protein characteristics, such as salt pre‐

cipitation, dialysis, column chromatography and gel electrophoresis

The immune system and antimatter production, antigens, immunoglobulins as well as immuno‐

chemical analysis methods, such as ELISA, agglutination test, precipitation techniques and im‐

munoblotting




fermentation types and their up‐ and downstream processes;

proteins, including enzymes, related to characterisation and use in the laboratory;

methods for purification and characterisation of proteins; and

the immune system, immunoglobulins and immunochemical methods.

Skills


conduct fermentation and quantify the product;

carry out enzyme‐kinetic measurements;

purify and characterise proteins and assess the results; and

apply immunochemical methods, assess the results and conduct basic error detection.

Competences


plan, quality assure and carry out tasks in the biotechnological laboratory; and

document, assess and disseminate results in the biotechnological laboratory.



6.6 Contents and learning outcomes for Spectrophotometric and potentiometric methods

Contents

UV/VIS, AAS and IR equipment and electrodes: instrumentation, application, calibration, sample

treatment, control, assessment of results and documentation




electromagnetic radiation at basic level;

equipment and analysis principles in spectrophotometry; and

equipment and analysis principles in potentiometry.

Skills


make and quality assure quantitative determinations;

prepare, operate and maintain spectrophotometers, pH meters and electrodes as well as con‐

duct basic error detection;

apply spectrophotometric methods for identification; and

make simple qualification of instruments.

Competences


plan, quality assure and conduct spectrophotometric and potentiometric analyses; and

document, assess and disseminate spectrophotometric and potentiometric analyses.

6.7 Contents and learning outcomes for Chromatographic methods

Contents

LC and GC equipment: instrumentation, application, calibration, sample treatment, control, as‐

sessment of results and documentation






the principle of chromatography;

the structure and function of LC and GC equipment at basic level;

the principles of controlling the selectivity of chromatography at basic level: the chemistry and

selectivity of stationary and mobile phases, pH and temperature; and

integration software.

Skills


make and quality assure qualitative and quantitative determinations;

prepare, operate and optimise chromatographic equipment and conduct basic error detection;

and

make basic methodology development.

Competences


plan, quality assure, conduct and optimise chromatographic methods; and

document, assess and disseminate chromatographic results.

6.8 Contents and learning outcomes for Biotechnological laboratory methodology and advanced techniques

Contents

DNA, RNA, structure and function, DNA/RNA techniques

DNA polymerases, restriction enzymes and ligases – prevalence and use. Standard PCR, detec‐

tion of PCR product

Cloning, genetic analysis, hybridisation and sequencing

Cell culture. Ministerial order on work with GMO, upgrading and downgrading procedures. Eth‐

ics






structure and function of DNA and RNA as well as protein synthesis;

molecular‐biology techniques

upgrading and downgrading of laboratories for genetic‐engineering work according to current

legislation; and

simple cell‐culture techniques.

Skills


use biotechnological/molecular‐biology techniques and possibly cell‐culture techniques;

clone DNA in a microorganism;

conduct method optimisation;

quality assure molecular‐biology analysis results; and

plan and organise their own long‐term work, considering materials, equipment, quality assur‐

ance, safety and time consumption.

Competences


plan, quality assure and carry out tasks safely in the molecular‐biology laboratory;

document, assess and disseminate results and suggest changes to colleagues and other collabo‐

ration partners;

apply knowledge and methods in new contexts; and

acquire skills and new knowledge in a structured context.

6.9 Contents and learning outcomes for Chemical technology laboratory methodology and advanced techniques

Contents

Qualification of equipment, validation of methods, method adjustment and development, plan‐

ning of long courses, knowledge of advanced techniques, such as ICP, MS and NMR






selected advanced laboratory techniques;

qualification of laboratory equipment at basic level; and

validation of analysis methods.

Skills


choose, apply and optimise selected advanced analysis techniques;

plan and organise their own long‐term work, considering materials, equipment, quality assur‐

ance, safety and time consumption.

Competences


plan and conduct complex laboratory tasks;

take part in qualification and validation;

document, assess and disseminate results and suggest changes to colleagues and other collabo‐

ration partners;

apply knowledge and methods in new contexts; and

acquire skills and new knowledge in a structured context.

6.10 Number of examinations in the compulsory educational components

There are three exams in the compulsory educational components.

The learning outcomes for the seven compulsory educational components below are documented

with two exams.

Chemistry and biochemistry (10 ECTS)

Laboratory technique and calculations (10 ETCS)

Quality assurance, communication and work environment (10 ETCS)

Microbiology (5 ECTS)



Fermentation, protein purification and characterisation as well as immunochemistry (10 ECTS)

Spectrophotometric and potentiometric methods (5 ECTS)

Chromatographic methods (10 ECTS)

The learning outcomes for the two compulsory educational components below are documented

with one exam.

Biotechnological laboratory methodology and advanced techniques (10 ECTS)

Chemical technology laboratory methodology and advanced techniques (10 ECTS)

7. Internship

The internship is completed in paid employment in one or more enterprises, cf. the Programme Or‐

der. The internship may be unpaid if it is completed abroad, and if the place of internship states that

paid internships are not common in the country in question. The internship is worth 50 ETCS credits.

The internship includes four educational components:

Workplace organisation and culture: 5 ECTS credits

Safety work/work environment: 5 ECTS credits

Quality systems: 5 ECTS credits

Laboratory‐technical methods: 35 ECTS credits

7.1 Learning outcomes for Workplace organisation and culture

Knowledge


the core areas and mission of the enterprise;

the organisation of the enterprise;

the communication and decision‐making processes of the laboratory; and

the procedures of the workplace for purchasing and ordering internal services.

Skills


adapt to the standards, behavioural patterns and values of the workplace.



Competences


collaborate and communicate with the different trade groups attached to the laboratory.

7.2 Learning outcomes for Safety work/work environment

Knowledge


the safety organisation of the enterprise;

the use and preparation of workplace instructions;

workplace assessment; and

waste handling procedures.

Skills


choose personal protective gear.

Competences


plan and carry out the laboratory work in a sound manner regarding safety and environment;

and

contribute to the drawing up of workplace instructions and workplace assessments.

7.3 Learning outcomes for Quality systems

Knowledge


the quality assurance procedures of the enterprise, including procedures that ensure reliable re‐

sults and procedures for documentation.

Skills


document their own work in respect of quality assurance procedures, including registration and

record‐keeping according to requirements set up.



Competences


contribute to the maintenance/elaboration of the quality assurance procedure of the enter‐

prise; and

contribute to the validation of the instruments and methods of the enterprise.

7.4 Learning outcomes for Laboratory‐technical methods

Knowledge


the main methods used at the workplace, including the principle and application of the methods.

Skills


apply a broad selection of the analyses and methods of the workplace.

Competences


plan, carry out and assess their own work.

7.5 Number of internship exams

The internship is documented with an exam.

8. Final exam project

The objective of the final exam project is to document the students' understanding of practice as

well as centrally applied theory and method in relation to a practical problem or issue based on a

specific assignment within the field of the programme.

The problem statement, which is sought solved in a final exam project, is drawn up by the student,

possibly in collaboration with a private or public enterprise. Relevant parts of the core areas of the

fields of study must be part of the project.

The institution approves the problem statement.

9. Credit transfer

Transfer credit is granted by the individual institution based on a specific prior learning assessment.

c a pr de pro che b scie · pr che nationa c ofes mic l section urri sion al a culu de nd b m fo...

Documents