COSTER GROUP SALES ORGANIZATION

AreA CompAny / e - mAil Address Telephone / FAx

HEAD OFFICES Coster Tecnologie Speciali S.p.A. Corso Como 15 TEL : +39 02636161sales@coster.com 20154 Milano (Italia) FAX : +39 0229006706

MACHINERY DIVISION Coster Tecnologie Speciali S.p.A. Via Leonardo da Vinci 4 TEL : +39 02339561info.machine@coster.com 20016 Pero Mi (Italia) FAX : +39 0233956372

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BENELUX, Robertpack Engineering B.V. Pascalweg 3, Industrieterrein Marslanden D TEL : +31 (38) 4652 080SCANDINAVIA sales.nl@coster.com 8013 RC - Zwolle, Netherlands FAX : +31 (38) 4657 076FRANCE, Coster s.à.r.l. ZI Mitry Compans Rue Gay Lussac TEL : +33 (1) 6467 9655MAGHREB sales.fr@coster.com 77290 Mitry Mory FAX : +33 (1) 6467 0404GERMANY, AUSTRIA, Coster Tecnologie Speciali GmbH Siemensstraße 22 TEL : +49 (7243) 5483-0POLAND, CZECH REPUBLIC sales.de@coster.com 76275 Ettlingen FAX : +49 (7243) 5483-54INDIA Coster India Packaging Pvt. Ltd. C-021-A, 2nd floor, Super Mart Commercial Complex-1 TEL : +91 (124) 404 3701

info@costerindia.com DLF Phase IV - Gurgaon-122016 Haryana FAX : +91 (124) 404 3704LATIN AMERICA Coster Packaging S.A. Ruta 8, Km 60 - Calle 14 y 9 TEL : +54 (0230) 4466 206

ventas.ar@coster.com B1629MXA Parque Ind. Pilar - Buenos Aires FAX : +54 (0230) 4496 664MALAYSIA Costerpack Sdn. Bhd. 5, Jalan Firma 3 Kawasan Perindustrian TEL : +60 (7) 357 3351

costerap-karen@costerpackmfg.com.my Tebrau IV - 81100 Johor Bahru, Johor FAX : +60 (7) 357 3349SINGAPORE Coster Asia-Pacific Pte. Ltd. 92, Hillview Ave., # 06 -12 Hillbrooks TEL : +65 9139 1468

sales.sg@coster.com 669592 Singapore FAX : +65 6891 3687SPAIN, PORTUGAL Costertec, S.A. Besalú, 4 TEL : +34 (93) 859 1038

sales.sp@coster.com 08570 Torelló - Barcelona FAX : +34 (93) 859 3510UNITED KINGDOM Coster Aerosols Limited Babbage Road, Stevenage TEL : +44 (1438) 367 763

sales.uk@coster.com Herts SG1 2EQ FAX : +44 (1438) 728 305U.S.A. Coster USA Inc. 1625 Shanahan Drive, South Elgin Illinois TEL : +1 (847) 760 6040

sales@costerusa.com 60177 USA FAX : +1 (847) 760 6035

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S IRAN Padine Co. Ltd. No. 24, 8th Ave. Ahmad Ghassir Ave. TEL : +98 (21) 8873 8833info@foumanchimie.com Tehran 15147 FAX : +98 (21) 8873 7686

TURKEY Aerosol Valf Sanayi A.S. Geposb-Gebze Plastikçiler Organize Sanayi TEL : +90 (262) 751 2713info@avlcoster.com Bölgesi Inönü mahallesi 7, Cadde Gebze/Kocaeli FAX : +90 (262) 751 2180

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BALTIC COUNTRIES, Sun Spray Packaging Ltd. Bolshaya Spaskaya St. - House 12, Office 50 TEL : +7 (495) 956 3218RUSSIA, C.I.S. bordoloi_p@yahoo.com 129010 Moscow FAX : +7 (495) 956 3259CANADA Norlimar Canada Inc. 104, Rue des Oblats, Lasalle TEL : +1 (514) 696 2947

ngoudreau@norlimar.com Québec H8R 3K8EGYPT, YEMEN, Cesam Engineering & Trading Co. I.Z. # 2, Str. # 81 btw. Rd # 18 & Rd # 20 TEL : +20 (2) 3833 9896GCC cesam@cesam-eg.com POB 153 October VI City - Giza 12573 Egypt FAX : +20 (2) 3833 5197GREECE, CYPRUS Paneuropean S.A. N. 17, Souri street TEL : +30 (210) 574 141417

pto@ath.forthnet.gr 121 31 Peristeri Athens FAX : +30 (210) 574 1418GUATEMALA Representaciones del Caribe S.A. 14 Avenida 7-12 Zona 14 Bodega # 8 TEL : +502 24 210 300

repca@repca.com Guatemala C.A. 01014 FAX : +502 24 210 301HUNGARY Turi Jolan Bukkfa u. 12 TEL : +36 (1) 325 5062

turi.jolan@t-online.hu 1028 Budapest FAX : +36 (1) 325 5062ISRAEL Maydan Representatives Ltd. Kehilat Saloniki str. 13 TEL : +972 (3) 540 3710

mayrep@bezeqint.net 69513 Tel Aviv FAX : +972 (3) 549 2524JAPAN Koike Chemical Co. Ltd. 3-2-1, Kinshi, Sumida-Ku TEL : +81 (3) 5610 5169

Tokyo 130-0013 FAX : +81 (3) 5610 5171LEBANON Jean Zakka Fils S.a.l. P.O. Box 90360 TEL : +961 (1) 870 942

info@zakkamultitec.com Jdeidet El-Maten FAX : +961 (1) 895 654ROMANIA Pluritrade S.r.l. Sos. Panduri, 7 TEL : +40 (21) 410 6706

dan.floroiu@pluritrade.ro 050651 Bucuresti FAX : +40 (21) 411 1172SWITZERLAND Pack-Part GmbH Kraftwerkstraße, 24 TEL : +41 (61) 811 1109

pack-part@bluewin.ch CH 4303 Kaiseraugst FAX : +41 (61) 811 2166TURKEY Metpak Temsilcilik Diş Ticaret Ltd. şti Merdivenköy Mh. şair Arşi Cd. TEL : +90 216 411 87 87

info@metpak.com.tr Nazenin Sk. Karadeniz Apt. 9/7 - 34732 Kadiköy Istanbul FAX : +90 216 478 53 53

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S BALTIC COUNTRIES, VA Intertrading AG Kantemirovskaya Street 58 TEL : +7 (495) 651 9335RUSSIA, C.I.S. marina.smirnskaya@gmail.com Office 7038 Moscow 114577BANGLADESH Orbit Corporation 89/ka, P.C Culture Housing Society TEL : +88 (02) 81 58 805

rokun@orbitcorpbd.com Shamoli, Mohammadpur, Dhaka - 1212 FAX : +88 (02) 81 59 957CHINA, TAIWAN, KOREA Anomatic (Suzhou) Metal Packaging Co. Ltd. 1999, LinHu Avenue, Fenhu Economic Development Zone TEL : +86 (512) 6326 9696

pjm@anomatic.com Wujiang, Jiangsu Province 215211, China FAX : +86 (512) 6301 6756IRAN Borna Khooshe Co. Flat 1, No.26, Souri Str. Ati Saz TEL : +98 21 2234 5737(PACKAGING COMPONENTS) info@bornakhooshe.com 1997657653 Tehran FAX : +98 21 2234 5737IRAN IMA Darou Afzar Co. Unit 8, 3rd Floor, N. 30 TEL : +98 21 88214976(MACHINERY) ojaghian@hotmail.com 37th Street Yousefabad Ave. Tehran FAX : +98 21 88210931SYRIA, JORDAN Gulf - Alfourat FZC P.O. Box 16670 TEL : +963 93 340 3370

ahmad.abdulmajeed@fourat-tc.com RAK-UAE FAX : +971 15 660 3267TURKEY Metpak Temsilcilik Diş Ticaret Ltd. şti Merdivenköy Mh. şair Arşi Cd. TEL : +90 216 411 87 87

info@metpak.com.tr Nazenin Sk. Karadeniz Apt. 9/7 - 34732 Kadiköy Istanbul FAX : +90 216 478 53 53

PHARMACEUTICAL FILLING MACHINES FOR AEROSOL, SPRAY AND DISPENSING PRODUCTS

MACHINERY DIVISION

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RCOSTER offers global service in the aerosol sector, leveraging the experience and know-how of both its valve and machine divisions

Coster Tecnologie Speciali, founded in the

early 1960’s, serves as a global partner in

the aerosol sector, offering aerosol com­

ponents (valves, pum ps, spray caps, stan­

dard and special actuat ors) and machin­

ery for fil l ing aerosol, spray and dispensing

products. With over 40 years experience in

the design and manufacture of machines,

Coster is a world leader in the provision

of equipment to companies in the pharma­

ceutical, household, technical prod ucts,

perfumery and cosmetics industr ies. Le­

veraging i ts experience and the latest ad­

vances in technology, Coster offers inno­

vative services and products designed to

meet customers’ needs and with the ob­

ject ive of enabl ing every customer to veri­

fy the qual i ty of Coster machines.

Filling of pharmaceutical products in glass bottles.

Above, compact indexing machine for can cleaning, filling liquid product, pump insertion and pump crimping.

Right, detail shows liquid product filling heads.

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Above: micro filling head and ceramic piston, whose extreme hardness guarantees zero contamination.

Right, from the top: a product metering cylinder (operates on syringe principle);a product filling head for levelling system;a liquid filling head for foamy products.

Coster pharmaceutical machines are designed to crimp 1” and 20 mm valves and pumps with maximum precision.Below: crimping head for 20 mm valves.Bottom right: close-up of the crimping jaw. The 32 petals enable precision of 0.05 mm in crimping. The crimping jaw is manufactured with a special material that enables 3 million maintenance-free cycles.Bottom left: same crimping jaw with container and 20 mm mounting cup.

COSTER is fully committed to safety, innovation and excellence in the designand manufacture of pharmaceutical machines

In order to guarantee maximum safety,

compliance and compatibi l i ty in the han­

dl ing of pharmaceutical products, al l Co­

ster pharmaceutical machines and l ines

are manufactured with the fol lowing spec­

if icat ions:

· designed and manufactured to faci l i tate

cGMP and ISO 14644­5:2004 compliance;

· AISI 316 L stainless steel construct ion;

· al l materials which come in touch with

product and propel lant would support reg­

ulatory (FDA etc.) approval;

· metering cyl inders are manufactured in

AISI 316 L stainless steel and are internal­

ly pol ished to assure smooth surface for

easy cleaning and to avoid contamination

of product and/or propel lant;

· ceramic (FDA­approved) piston rods sui t­

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able for abrasive suspension products f i l l ­

ing;

· systems designs suitable for both single

stage and two stage f i l l ing of canisters;

· f i l l ing head design ful ly compatible with

external homogenizat ion and re­circulat ion

systems;

· metering cyl inders designed for high f i l l

accuracy (±1%, max ±0.05 ml);

· food contact approved and CFR compliant

PTFE gaskets and Viton® o­rings;

· cr imping heads enable precision to 0.05

mm on crimping dimensions and 3 mil l ion

maintenance­free cycles;

· al l equipment is manufactured and tested

using HFA 134a as standard and is 100%

suitable for al l current aerosol propel lants

(LPG, DME, Nitrogen, HFA, etc.) ;

· al lows for connection to cleaning system

for easy CIP/SIP;

· quick release systems al low easy parts

replacement;

· units equipped with clamp connections.

Close-ups of Coster indexing filling machine for MDI.Above: valve mount testing head and crimping head.Left: filling head of high precision micro metering cylinder for pharmaceutical products and valve insertion head.

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COSTER works closely with customers assuring full support from early development to full-scale production, installation and training

Coster has adopted a customer­facing

qual i ty system, committed to continuously

improve both i ts products and services.

I t is no longer enough to offer a good

product at a good price; i t is essential that

product offer ings are accompanied and

enhanced through ful l­service technical

assistance.

Coster Customer Care Service offers world­

wide pre­ and post­sales technical sup­

port, including:

­ 2D/3D CAD­aided instal lat ion design;

­ database assisted management of pro­

duction and design;

­ prototypes;

­ R&D integrated with design and test ing;

­ instal lat ion and customer training;

­ documentat ion for operat ion, maintenan­

ce and val idat ion to enable prof icient use

and complete sat isfact ion of legislat ive

requirements for al l production and test­

ing units;

­ cert i f icat ions of conformance with Euro­

pean safety rules and to the Atex standard

for operat ions in areas at r isk of explosion

and/or r isk of f i re.

3-D layout of the machine for filling plastic bottles for the pharmaceutical industry. The machine is part of an electronic indexing line which performs the following operations: sorting and selection of empty bottles; filling liquid product; pump insertion; testing of mounted pumps, pre-crimping and crimping of pumps; insertion of leaflet in cap, cap mounting and labelling of bottles.Above, detail of pump

mount testing head and pre-crimping head.

Below, view of the filling machine.

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Compact automatic continuous high-speed rotary filling line for MDI. This line has a maximum production capacity of 120 CPM.

COSTER offers a wide range of filling and ancillary machines, from semi-automatic units to fully automatic high-speed rotary lines

Coster pharmaceutical machines range from

semi­automatic (laboratory and low volume)

machines to ful ly automatic high­perfor­

mance machines, with a production capac­

ity ranging from 10 to 250 cans per minute

(CPM). Easy to operate, highly f lexible, rel i­

able, secure, long­lasting, low­maintenance,

Coster pharmaceutical machines are based

on a modular design and make use of the

same operating heads (product fillers, crimp­

ers, propellant fillers) to guarantee continu­

ity between laboratory testing and full­scale

production, minimising re­verif icat ion.

Above: left, semi-automatic unit for crimping; right, semi-automatic unit for propellant filling. Semiautomatic units are suitable for laboratory and/or small-scale production (20-25 CPM).

COSTER pharmaceutical machines allow safe handling of a wide range of products and propellants

Coster pharmaceutical f i l l ing machines can

be used to f i l l glass, plast ic and alumin­

i um containers in a range of 0.15 ml to

1000 ml and to handle both 20 mm and 1”

valves, as wel l as various pump configu­

rat ions.

Coster machines have the capabi l i ty to me­

ter products ranging f rom un­pressur­

ized water­based so lut ions to aggress ive

products ranging f rom a lcohol ic emul­

s ions to aeroso l suspens ions and are

equipped to f i l l a l l types of propel lants ,

as HFA 134a, HFA 227, LPG, t rad i t iona l

CFC’s, n i t rogen.

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Above: automatic indexing unit for filling pharmaceutical products either in standard aerosol or dual-compartment systems (Bag-On-Valve). Line speed up to 60 CPM.

Bottom: close-ups of a Coster electronic automatic unit for 20 mm pump insertion on glass bottles, pump crimping and cap fitting on can. This unit has a production capacity of 60 CPM.

Bottom left: view of pump crimping and cap insertion.

Bottom right: view of central machine column showing cap insertion system.

TURKEY TEL: +90 216 411 87 87FAX: +90 216 478 53 53

Metpak Temsilcilik Diş Ticaret Ltd. Ştiinfo@metpak.com.tr

Barbaros Mah. Apaydın Sok. No. 2 D. 3-434746 Ataşehir - Istanbul

COSTER GROUP SALES ORGANIZAT ION

AREA ADDRESSCOMPANY / E-MAIL TELEPHONE / FAX

HEAD OFFICES Coster Tecnologie Speciali S.p.A.sales@coster.com

Via Vincenzo Monti 2320016 Pero (MI) – Italy

TEL: +39 02636161FAX: +39 0229006706

MACHINERY DIVISION Coster Tecnologie Speciali S.p.A.info.machine@coster.com

Via Leonardo da Vinci 420016 Pero (MI) – Italy

TEL: +39 02339561FAX: +39 0233956372TEL: +31 (38) 4652 080FAX: +31 (38) 4657 076

BENELUX,SCANDINAVIAFRANCE,MAGHREB

Coster Benelux & Scandinavia B.V.sales.nl@coster.com

Pascalweg 3, Industrieterrein Marslanden D 8013 RC - Zwolle, Netherlands

TEL: +33 (1) 6467 9655FAX: +33 (1) 6467 0404

Coster s.à.r.l.sales.fr@coster.com

ZI Mitry Compans Rue Gay Lussac77290 Mitry Mory

GERMANY, AUSTRIA,POLAND, CZECH REPUBLIC

TEL: +49 (7243) 5483-0FAX: +49 (7243) 5483-54

Coster Tecnologie Speciali GmbHsales.de@coster.com

Siemensstraße 2276275 Ettlingen

INDIA TEL: +91 (124) 404 3701FAX: +91 (124) 404 3704

Coster India Packaging Pvt. Ltd.info@costerindia.com

C-021-A, 2nd floor, Super Mart Commercial Complex-1DLF Phase IV - Gurgaon-122016 Haryana

LATIN AMERICA TEL: +54 (0230) 4466 206FAX: +54 (0230) 4496 664

Coster Packaging S.A.ventas.ar@coster.com

Ruta 8, Km 60 - Calle 14 y 9B1629MXA Parque Ind. Pilar - Buenos Aires

MALAYSIA TEL: +60 (7) 357 3351FAX: +60 (7) 357 3349

Costerpack Sdn. Bhd.costerap-karen@costerpackmfg.com.my

5, Jalan Firma 3 Kawasan PerindustrianTebrau IV - 81100 Johor Bahru, Johor

SINGAPORE TEL: +65 9139 1468FAX: +65 6891 3687

Coster Asia-Pacific Pte. Ltd.sales.sg@coster.com

92, Hillview Ave., # 06 -12 Hillbrooks669592 Singapore

SPAIN,PORTUGAL

TEL: +34 (93) 859 1038FAX: +34 (93) 859 3510

Costertec, S.A.sales.sp@coster.com

Besalú, 408570 Torelló - Barcelona

UNITED KINGDOM TEL: +44 (1438) 367 763FAX: +44 (1438) 728 305

Coster Aerosols Limitedsales.uk@coster.com

Babbage Road, StevenageHerts SG1 2EQ

U.S.A. TEL: +1 (847) 760 6040FAX: +1 (847) 760 6035

Coster USA Inc.sales@costerusa.com

1625 Shanahan Drive, South Elgin Illinois60177 USA

IRAN TEL: +98 (21) 8873 8833FAX: +98 (21) 8873 7686

Padine Co. Ltd.info@foumanchimie.com

TURKEY TEL: +90 (262) 751 2713FAX: +90 (262) 751 2180

Aerosol Valf Sanayi A.S.info.avs@fareva.com

Geposb-Gebze Plastikçiler Organize SanayiBölgesi Inönü mahallesi 7, Cadde Gebze/Kocaeli

CANADA TEL: +1 (514) 696 2947Norlimar Canada Inc.sales.nl@coster.com

104, Rue Des Oblats, LasalleQuébec H8R 3K8

EGYPT, YEMEN,GCC

TEL: +20 (2) 3833 9896FAX: +20 (2) 3833 5197

Cesam Engineering & Trading Co.cesam@cesam-eg.com

I.Z. # 2, Str. # 81 btw. Rd # 18 & Rd # 20POB 153 October VI City - Giza 12573 Egypt

GREECE,CYPRUS

TEL: +30 (210) 574 141417FAX: +30 (210) 574 1418

Paneuropean S.A.pto@ath.forthnet.gr

N. 17, Souri street121 31 Peristeri Athens

GUATEMALA TEL: +502 24 210 300FAX: +502 24 210 301

Representaciones del Caribe S.A.repca@repca.com

14 Avenida 7-12 Zona 14 Bodega # 8Guatemala C.A. 01014

HUNGARY TEL: +36 204 142 562Unlimited Business Ltd.olga.csatari@t-online.hu

Utas utca 91025 - Budapest

ISRAEL TEL: +972 (3) 540 3710FAX: +972 (3) 549 2524

Maydan Representatives Ltd.mayrep@bezeqint.net

Kehilat Saloniki str. 1369513 Tel Aviv

JAPAN TEL: +81 (3) 5610 5169FAX: +81 (3) 5610 5171

Koike Chemical Co. Ltd.t.hosokawa@kck.co.jp

3-2-1, Kinshi, Sumida-KuTokyo 130-0013

LEBANON TEL: +961 (1) 870 942FAX: +961 (1) 895 654

Jean Zakka Fils S.a.l.secretariat@zakkamultitec.com

P.O. Box 90360Jdeidet El-Maten

ROMANIA, BULGARIA,MOLDOVA

TEL: +40 (21) 407 4903FAX: +40 (21) 313 8857

Pluritrade S.r.l.office@pluritrade.ro

GreenGate offices, 22 Tudor Vladimirescu Blvd.5th Floor, 5th District - 050883 Bucharest Romania

SWITZERLAND TEL: +41 (61) 811 1109FAX: +41 (61) 811 2166

Pack-Part GmbHinfo@pack-part.ch

Challerenweg, 1CH 4303 Kaiseraugst

ALGERIA, EGYPT, JORDAN,SYRIA, YEMEN, GCC

TEL: +971 720 426 68FAX: +971 15 660 3267

Gulf - Alfourat FZCahmad.abdulmajeed@fourat-tc.com

P.O.Box: 16670RAK-UAE

BALTIC COUNTRIES,RUSSIA, C.I.S.

TEL: +7 (495) 651 9335VA Intertrading AGmarina.smirnskaya@gmail.com

Kantemirovskaya Street 58Office 7038 Moscow 114577

BANGLADESH(PACKAGING COMPONENTS)

TEL: +880 (2) 81 58 805FAX: +880 (2) 81 59 957

Orbit Corporationrokun@orbitcorpbd.com

BANGLADESH(MACHINERY)

TEL: +880 (2) 89 31 056FAX: +880 (2) 89 31 139

Precisa Techno Tradeprecisa@precisabd.com

Road 27, House 39, Sector 7Uttara, Dhaka - 1230

CHINA, TAIWAN,KOREA

TEL: +86 (512) 6326 9696FAX: +86 (512) 6301 6756

Anomatic (Suzhou) Metal Packaging Co. Ltd.pjm@anomatic.com

1999, LinHu Avenue, Fenhu Economic Development ZoneWujiang, Jiangsu Province 215211, China

IRAN(MACHINERY)

TEL: +98 21 88214976FAX: +98 21 88210931

IMA Darou Afzar Co.ojaghian@hotmail.com

Unit 8, 3rd Floor, N. 3037th Street Yousefabad Ave. Tehran

TURKEY TEL: +90 216 411 87 87FAX: +90 216 478 53 53

Metpak Temsilcilik Diş Ticaret Ltd. Ştiinfo@metpak.com.tr

Barbaros Mah. Apaydın Sok. No. 2 D. 3-434746 Ataşehir - Istanbul

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No. 53, Rasht Street, Hafez Ave. Tehran, Iran - 1591818971

"The Emporium Building" - House# 14/1, Level - 13 (C -13) Shamoli, Dhaka - 1207