insufficienza renale acuta nosocomiale e in comunità · insufficienza renale acuta nosocomiale e...
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Insufficienza renale acuta nosocomiale e in comunità
Giuseppe GrandalianoUOC di Nefrologia, Dialisi e
Trapianto
Definitions proposed for the identification and staging of acute
kidney injury
Acute kidney injury: the global burden
Community-acquired AKIAcute kidney injury diagnose at hospital
admission
Hospital acquired AKIAcute kidney injury developed during the
hospital stay
KDIGO-based acute kidney injury criteria operate differently in hospitals and the community—findings from a
large population cohort
Sawhney S et al. Nephrol Dial Transplant (2016) 31: 922–929
Incidence and presentation
Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired
Acute Kidney Injury
Hsu C-N et al. Medicine 95(19):e3674, 2016
Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired
Acute Kidney Injury
Hsu C-N et al. Medicine 95(19):e3674, 2016
Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired
Acute Kidney Injury
Hsu C-N et al. Medicine 95(19):e3674, 2016
Oliguria
Huang L et al. Kidney Blood Press Res 2019;44:879-896
Clinical Characteristics and Outcomes of Community-Acquired versus Hospital-Acquired
Acute Kidney Injury: A Meta-Analysis
Need for HD
Huang L et al. Kidney Blood Press Res 2019;44:879-896
Clinical Characteristics and Outcomes of Community-Acquired versus Hospital-Acquired
Acute Kidney Injury: A Meta-Analysis
Risk factors
Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI
Wonnacott A et al. Clin J Am Soc Nephrol 9: 1007-1014, 2014
Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults
Xu X et al. Clin J Am Soc Nephrol 10: 1510–1518, 2015
Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults
Xu X et al. Clin J Am Soc Nephrol 10: 1510–1518, 2015
Seasonality of acute kidney injury incidence and mortality among hospitalized patients
Iwagami M et al. Nephrol Dial Transplant 33: 1354-1362, 2018
Seasonality of acute kidney injury incidence and mortality among hospitalized patients
Iwagami M et al. Nephrol Dial Transplant 33: 1354-1362, 2018
Seasonality of acute kidney injury incidence and mortality among hospitalized patients
Iwagami M et al. Nephrol Dial Transplant 33: 1354-1362, 2018
Seasonality of acute kidney injury incidence and mortality among hospitalized patients
Iwagami M et al. Nephrol Dial Transplant 33: 1354-1362, 2018
Seasonality of acute kidney injury incidence and mortality among hospitalized patients
Iwagami M et al. Nephrol Dial Transplant 33: 1354-1362, 2018
Causes
Incidence, Severity, and Outcomes of AKI Associated with Dual Renin-Angiotensin System Blockade
Palevsky P et al. Clin J Am Soc Nephrol 11: 1944-1953, 2016
Incidence, Severity, and Outcomes of AKI Associated with Dual Renin-Angiotensin System Blockade
Palevsky P et al. Clin J Am Soc Nephrol 11: 1944-1953, 2016
Combined use of NSAID with diuretics and/or RAS inhibitors in the community increases the risk of AKI
Dreischulte T et al. Kidney Int 88: 396-403, 2015
Combined use of NSAID with diuretics and/or RAS inhibitors in the community increases the risk of AKI
Dreischulte T et al. Kidney Int 88: 396-403, 2015
Increased prevalence of acute tubulointerstitial nephritis
Goicoechea et al. Nephrol Dial Transplant 28: 112-115, 2013
Increased prevalence of acute tubulointerstitial nephritis
Goicoechea et al. Nephrol Dial Transplant 28: 112-115, 2013
Clinical and laboratory features at presentation in patients with AIN
Valluri et al. Q J Med 2014, doi:10.1093/qjmed/hcu236
Valluri et al. Q J Med 2014, doi:10.1093/qjmed/hcu236
Acute interstitial nephritis with proton pump inhibitor use
Outcomes
Incidence, Outcomes, and Risk Factors of Community-Acquired and Hospital-Acquired
Acute Kidney Injury
Hsu C-N et al. Medicine 95(19):e3674, 2016
Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI
Wonnacott A et al. Clin J Am Soc Nephrol 9: 1007-1014, 2014
Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI
Wonnacott A et al. Clin J Am Soc Nephrol 9: 1007-1014, 2014
Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI
Wonnacott A et al. Clin J Am Soc Nephrol 9: 1007-1014, 2014
Chronic Dialysis Among Survivors of Acute Kidney Injury Requiring Dialysis
Wald R et al. JAMA 2009, 302: 1179
Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI
Wonnacott A et al. Clin J Am Soc Nephrol 9: 1007-1014, 2014
Epidemiology and Outcomes in Community-Acquired Versus Hospital-Acquired AKI
Wonnacott A et al. Clin J Am Soc Nephrol 9: 1007-1014, 2014
Huang L et al. Kidney Blood Press Res 2019;44:879-896
Clinical Characteristics and Outcomes of Community-Acquired versus Hospital-Acquired
Acute Kidney Injury: A Meta-Analysis
LoHS
Renalrecovery
Huang L et al. Kidney Blood Press Res 2019;44:879-896
Clinical Characteristics and Outcomes of Community-Acquired versus Hospital-Acquired
Acute Kidney Injury: A Meta-Analysis
mortality
Huang L et al. Kidney Blood Press Res 2019;44:879-896
Clinical Characteristics and Outcomes of Community-Acquired versus Hospital-Acquired
Acute Kidney Injury: A Meta-Analysis
What can we do?
Acute Kidney Injury in the Era of the AKI E-Alert
Holmes J et al. Clin J Am Soc Nephrol 11: 2123-2131, 2016
Acute Kidney Injury in the Era of the AKI E-Alert
Holmes J et al. Clin J Am Soc Nephrol 11: 2123-2131, 2016
Impact of Electronic AKI Alerts With Automated Nephrologist Consultation on Detection and
Severity of AKI
Park S et al. Am J Kidney Dis 71: 9-19, 2017
Impact of Electronic AKI Alerts With Automated Nephrologist Consultation on Detection and
Severity of AKI
Park S et al. Am J Kidney Dis 71: 9-19, 2017
Impact of Electronic AKI Alerts With Automated Nephrologist Consultation on Detection and
Severity of AKI
Park S et al. Am J Kidney Dis 71: 9-19, 2017
Nephrologist follow-up improves all-cause mortality of severe acute kidney injury survivors
Harel Z et al. Kidney Int 83: 901–908, 2013
Nephrologist follow-up improves all-cause mortality of severe acute kidney injury survivors
Harel Z et al. Kidney Int 83: 901–908, 2013
Thank you for your attention!