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    WHY VC’S SHOULD CONSIDER

    FUNDING START-UP BIOTECHS 

    A PRESENTATION AT BIOMALAYSIA 2011KUALA LUMPUR 

    BY

    SANJAY K. SEHGAL

    MANAGING PARTNER & CEO

    EAST WEST CAPITAL PARTNERS 

    Life Sciences & Healthcare Principal Investments and Corporate Finance AdvisoryNovember 2011

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    East West Capital Partners

    2

    Who are East

    West Capital

    Partners

    (“EWCP”)? 

    Healthcare/Life Sciences Investments and Corporate Finance Advisory

    Headquartered out of Singapore; Presence in London, Malaysia, and India

    4 Partners with over a 100 years of combined Deep Domain and Global

    Operational and Financial Expertise

    What is

    EWCP’s

    Focus andInvestment

    Strategy?

    FOCUS

    oFacilities (hospitals, specialty clinics)

    oServices (clinical research organizations, healthcare insurance, IT)

    oPharma (specialty drug delivery technologies, manufacturing)

    oMedical Technology (e.g. OEM, manufacturing/distribution)

    Knowledge transfer and IP development from West to East and East to West

     STRATEGY:

    We are Engaged hands-on value-add investors

    We seek control or effective control investments

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    Topic is: Why VCs Should  consider funding

    start-up Biotechs

    Should the Question be the Other Way Around?

    that is…

    3

    Why Should  VCs consider funding start-up Biotechs?

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    The VC Money Cycle – Is It Alive & Well?

    4

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    Who are VCs?

    5

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    VCs Usually Know What They are

    Investing In, right?

    6

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    How about Biotech VCs?

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    Biotech

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    What do VCs Really Want?

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    How Long are VCs Prepared to Wait?

    9

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    The Essential Nature of Biotech

    10

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    What is the Typical Biotech?

    11

    Revenues

    Profits/ (Losses)

    Or

    Investment

    Yr 1 Yr 2 Yr 3 Yr 4 Yr 5

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    What has Changed so Dramatically for

    the Biotech Industry? First…

    12

    “Our portfolio has had seven NDAsubmissions since 2008, with five

    approved and two still pending. That

    should be a success, except it has taken

    twice as long to get there as it used to

    five or six years ago. The math with the

    FDA just doesn’t work anymore for us

    in terms of a venture fund lifecycle…

    It’s incredibly frustrating to watch this

    happen…”

    Quote fromKate Mitchell of Scale Venture Partners

    (BofA’s Venture group who stopped

    investing in biotech in November 2011)

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    What has Changed so Dramatically for

    the Biotech Industry? Second…

    13

    Uncertain Exit for Investors

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    And so…

    Where are the Returns in Biotech?

    14

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    The Mis-match Between What VCs Want

    and the Fundamental Nature of Biotech

    15

    VCs Biotech

    What VCs want:

    -Low Risk-Low Investment

    -High Return

    -Pronto!

    What Biotech offers:

    -High Risk-High Investment

    -Binary outcomes

    -Years of Waiting

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    Given this Mis-match, Why Do VCs

    Invest in Biotech?

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    Returns – looking for the next BILLION dollar home-run

    Superman syndrome…I believe I can pick the winners

    Portfolio – Investors want diversification to spread risk

    Doing good – Bringing a benefit to humanity, e.g., stem cells

    Bragging rights – Being part of the next Big Thing

    Government support and encouragement

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    So, Should VCs Invest in Start-up Biotechs?

    17

    H Sh ld Bi t h C i P

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    How Should Biotech Companies Prepare

    Themselves for this New Paradigm? 1 of 2

    18

    Understand your VC

    Try to get funding up to a clear valuation point

     – avoid being caught short of cash mid-way

    H Sh ld Bi t h C i P

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    Be more capital efficient:

    Leverage emerging markets

    Enter into risk-sharing deals with suppliers

    Get Government support / grants Be Virtual

    De-risk: Either find a near-term revenuemodel or identify an interested license or joint

    venture partner early on

    How Should Biotech Companies Prepare

    Themselves for this New Paradigm? 2 of 2

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    C O N T A C T

    Sanjay K. SehgalM A N A G I N G P A R T N E R & C E O

    Tel: +65 9675 [email protected]

    WHY VC’S SHOULD CONSIDER

    FUNDING START-UP BIOTECHS? 

    A PRESENTATION AT BIOMALAYSIA 2011

    KUALA LUMPUR 

    Life Sciences & Healthcare Principal Investments and Corporate Finance AdvisoryNovember 2011