levels of organization life is built on successive levels of increasing complexity: chemical (or...

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Levels of Organization• Life is built on successive levels of

increasing complexity:• Chemical (or Molecular)• Cellular• Tissue• Organ• Organ System• Organism

OrganismLevel

Integumentary

SkeletalMuscular

NervousEndocrine

CardiovascularLymphatic

RespiratoryDigestive

Urinary

Reproductive

OrganLevel

Theheart

Cardiacmuscletissue

Tissue Level

Cellular Level

Heartmuscle

cell

Protein filaments

Complex proteinmolecule

Atoms incombination

Chemical orMolecular Level

OrganSystem Level

Overview of Organ Systems• The human body is arranged in 11

organ systems:• Integumentary• Skeletal• Muscular• Nervous• Endocrine

• Cardiovascular• Lymphatic• Respiratory• Digestive• Urinary• Reproductive

The Integumentary System

Figure 1-2(a)

The Skeletal System

Figure 1-2(b)

The Muscular System

Figure 1-2(c)

The Nervous System

Figure 1-2(d)

The Endocrine System

Figure 1-2(e)

The Cardiovascular System

Figure 1-2(f)

The Lymphatic System

Figure 1-2(g)

The Respiratory System

Figure 1-2(h)

The Digestive System

Figure 1-2(i)

The Urinary System

Figure 1-2(j)

Male Reproductive System

Figure 1-2(k)

Female Reproductive System

Figure 1-2(l)

Introduction to Organ Systems

• The body can be divided into 11 organ systems, but all work together and the boundaries between them aren’t absolute.

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Homeostatic Regulation• Homeostasis• Maintains stable internal conditions

• Temperature• Ionic concentrations• Blood sugar levels, etc.

• Utilizes negative feedback mechanisms

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Homeostatic Regulation• Regulation depends on:

• Receptor sensitive to a particular stimulus• Effector that affects the same stimulus

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

RECEPTOR

Thermometer

STIMULUS:Room temperature

rises

Normalconditiondisturbed

HOMEOSTASISNormalroom

temperature

RESPONSE:Room temperature

dropsNormalconditionrestored

EFFECTOR

Air conditionerturns on

Sendscommands

to

Informationaffects

CONTROL CENTER(Thermostat)

20o 30o 40o

Homeostatic Regulation• Negative Feedback:

• Variation outside normal limits triggers automatic corrective response

• Response negates disturbance

RECEPTOR

Body’stemperature

sensorsSTIMULUS

Body temperaturerises above 37.2oC(99oF)

RESPONSE

Increased blood flowto skinIncreased sweatingStimulus removedHomeostasis restored

Controlmechanismwhen body

temperaturerises

EFFECTOR

Blood vesselsand sweat

glands in skin

Negativefeedback

Sendscommands

to

Informationaffects

Informationaffects

CONTROLCENTER

Thermoregulatorycenter in brain

Sendscommands

to

EFFECTOR

Blood vesselsand sweat glands

in skinSkeletal muscles

Negativefeedback

Controlmechanismwhen body

temperaturefalls

RECEPTOR

Body’stemperature

sensors STIMULUS

Body temperaturefalls below 37.2oC(99oF)

RESPONSE

Decreased blood flowto skinDecreased sweatingShiveringStimulus removedHomeostasis restored

Homeostatic Regulation•Positive Feedback:• Stimulus produces response that reinforces the

stimulus• Response rapidly completes critical process

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

Homeostatic Regulation• Homeostasis and Disease • Failure of homeostatic regulation• Symptoms appear• Organ system malfunction

Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings

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