frow & calvert igem talk
TRANSCRIPT
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H
umanP
ractices?
iG
EMNewc
astlemeet-up
21Ju
ly2010
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Reportsonsynth
eticbiolo
gy
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ApottedhistoryofHu
manPractices
1990s:HumanGenomeProject
5%offundingshouldg
otoELSIres
earch
ELSI=Ethical,LegalandSocialIssues
ELSA
=Ethical,Legalan
dSocialAspects
E3LS
=Ethical,Environm
ental,Economic,
LegalandSocialIssues
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ApottedhistoryofHu
manPractices
2000s:Expandedtoincludeothera
reasofnew
&
emergingtechnologies
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ApottedhistoryofHu
manPractices
HumanPracticesisconductedalongsid
ethescience,
ratherthan
aftertheresea
rchhasbeen
completed
NameHum
anPractices
waschosento
makethepoint
thatscience
isitselfahum
anpractice
Berkeley20
07iGEM:firstHumanPract
icesproject
PrizeforBe
stHumanPra
cticesAdvanc
eintroducedin
2008
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2009win
nersofHumanP
ractices
Paris:
alabbookrecordofregulard
iscussions
asociologic
alreport
compilinga
listofusefulrefere
nces
Imperial:
interviewsw
ithteammembers
2shortwrittenpapers
buildingsafetyconsiderations
intothedesignoftheirproject
Bothprojectsquitereflective
,focusedaroundtheteam
Bothteamshadsocialscien
tistsembeddedaspartofthe
teamforsom
e/allofthesu
mmer
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Other20
09iGEM
activitie
s
SURVEYS!!
Atleast15tea
ms
Outreachact
ivitiesforhigh-schoolstudents
e.g.Alberta,ArtScienceBangalore,Dre
sden,UCSF,Waterloo
Qualitativein
terviewswithacademics,stude
nts,politicians
e.g.NTU,UCL
,Southampton
Onlinetutorials&tool-kits
e.g.Berkeley,
Chicago,Virginia
Writingreports&pamphlets
e.g.Bologna,Ottawa,Valencia
StudyofDIYBio/BioArt/Regulatoryfram
eworks
e.g.PKUBeijing/Osaka/Edinburgh
Futuresworkshopswithdesigners
e.g.Cambridge
Ethicsconfe
renceinSecon
dLife
e.g.Calgary
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Thishousesupportsthedevelo
pmentofartific
iallyengineeredlife
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ArtScience
Banga
lore
iGEM2009
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WhatcountsasH
umanP
ractices?
Riskassessm
ent/feasibilitystudyforaspecific
application
Outreachactivities
Somethingthatrelatestoyour
localcommunity
(e.g.bringingE.coli
coalstoNewc
astle?)
Writtenreport
onsomeinterestingaspect(s)ofsyntheticbiology
Journalclub
sessionstodiscu
ssarticlesandreportsonhuman
practicesissues
Areflectivejournal/blog/hum
anpracticeslab
book
Aplay/dance
/poem/artwork
/film/sciencefictionstory
Useofnewm
ediatoexploreaparticularissue
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SomeHumanPracticesq
uestions
Sciencefunding
andpolicy:how
issyntheticbiolo
gybeingfunded
in
differentcountries?Howmuchp
ublicandprivate
moneyisbeing
invested?Aretherenationaldiffe
rencesinregulatoryframeworks?
Aretherenation
aldifferencesin
humanpractices
approachestowards
syntheticbiolog
y?E.g.istheUS
moreconcerned
aboutbiosecurity?
Whatcanwelearnfromstudying
pastexamplesofscience&
technology,e.g.syntheticchemistry,nanotechnology?
Howissyntheticbiologyreportedinthemedia?
Whoisthesyntheticbiologycom
munity?
Conceptualissu
es,e.g.Whatisapart?
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iGEM-sp
ecificqu
estions
HowdoesiGEMcomparewith
othersciencecompetitions(e.g.
theFirstRoboticsCompetition
)?
Whathuman
practicesissues
doestheiGEMc
ompetitionitself
raise?
HowwouldyouredesigntheiGEMcompetition
tomakeitmore
useful,ortod
evelopparticularapplications,etc
?
iGEMasksth
equestion:Can
simplebiologica
lsystemsbebuilt
fromstandard,interchangeableparts?Orisbio
logysimplytoo
complicatedtobeengineered
inthisway?
Howwouldyougoabouta
nsweringthisquestion?What
differenttypesofanswers
/approachescou
ldyouuse?
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SomeB
IGIDEAS
Bio
safety
Bios
ecurity
Life
Intellectu
alproperty
Publicacce
ptance/understanding
/engageme
nt
Interdis
ciplinarity
Standards
Languageandmetaphor
Expectationsandfutures
Reg
ulation
Aestheticsanddesign
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SomeB
IGIDEAS
Bio
safety
Bios
ecurity
Life
Intellectu
alproperty
Publicacce
ptance/understanding
/engageme
nt
Interdis
ciplinarity
Stan
dards
Languageandmetaphor
Expectation
sandfutures
Reg
ulation
Aestheticsanddesign
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INTE
LLECTU
ALPROP
ERTY
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Intellectualprop
erty
Illustration:AndrewRaeinWired15/09
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Ownersh
ip,sharingandinnovation
www.genomicsne
twork.ac.u
k
AnaimofiG
EMcompetitio
nistobuildac
ommunity
whichsharesvaluesabout
safety,security
andopen
access
Benefitsof
openness:
Itisdemocratic
Itisgood
forscienceand
innovation
Itwillpre
ventthedominan
ceofmultination
alcompanies
thehacker
culturevalueslikeelegantdes
ign,creativity
andsharing
beneficialworksofengineerin
gforall,will
spreadtob
iology(Cohn2
005)
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Ownersh
ip,sharingandinnovation
Somepeopleworryaboutsyntheticbiologybecoming
widelyacce
ssible:
Theythink
thewrongpeoplecouldusethetechnology
Hackersd
ontalwayshave
agoodreputatio
n
WillopenaccesstoBioBric
ksmeanthatitb
ecomeshardtoget
patentsan
dmakeprofits?
Intellectualproperty,open
ness,access
andsecuritya
re
interconnec
ted
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INTERDISC
IPLINA
RITY
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IN
TERDISC
IPLINAR
ITY
Aconfluenceofdisciplines
Biologists,e
ngineers,com
puterscientis
ts
Physicists?Chemists?
Socialscie
ntists??Designe
rs??Memberso
fthepublic??
Whatareth
eirroles?Wha
tskills,knowledgeorexpertise
dotheybrin
gtosynthetic
biology?
Whatideas
orconceptsareshapingsyn
theticbiology?
Wheredotheseideascomefrom?
Doesever
yoneunderstand
syntheticbiologythesameway?
Is
thisimportant??
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STANDARDS
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Stan
dards
Creatingstand
ardbiologicalparts
Interchange
able(standardsfordesign)
Predictable
(standardmeasuresofbeha
viour)
Instandardconditions?R
obustovertim
e?
Whyhavestandards?
Toensureq
uality,safety
Topromote
compatibility,
interoperability
Economies
ofscaleandw
ork(re)organization
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Stan
dards
BUTdostandardsreducesc
opeforinnovation?
Questionsabo
utstandards
Onestanda
rdormultiplestandards?
Whentodecideonthem?
Whodecide
s?
Whatconsiderationsfeed
intostandards?
Technical,legal,economic,social?
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EXPEC
TATIONSANDFUTURES
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Expectationsandfutures
Discussionofthe
futurehas
realeffects
inthepres
ent
Expectatio
nsare
necessary
tobuilda
newfield
Theyarealsolikelyto
leadtouneaseand
concern
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Syntheticbiology
asahuman
practice
Scientifica
ndtechnolog
icaldevelopm
entsarethe
resultofch
oices,suchasfundingde
cisions
Creatinga
newfieldreq
uirestechnic
al,social,
economicandpoliticalr
esources
Syntheticb
iologistsare
notjustinvolvedinbuildin
g
noveltechnologies;theyarealsobuildinganew
community
Willsynthe
ticbiologists
ofthefuture
havetobe
knowledge
ableabouthumanpractices,asthefield
developsa
ndgrows?
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Question
sforHumanPra
ctices
Whatdowewanttoget
outofourHumanPractices
activitiesasateam?
ArethereinterestingHu
manPractice
squestions
directlyrelevanttoouriGEMproject?
Whatcontributioncould
thisworkma
ketoiGEM
moregene
rally?Tothe
disciplineofsynthetic
biology?