pivotal data on myeloid disorders from the 2013 hematology conference
DESCRIPTION
Pivotal Data on Myeloid Disorders From the 2013 Hematology Conference. Activity Goals. Myelofibrosis. Newly Identified Biological Pathway May Aid Diagnosis, Treatment of MPNs. Ruxolitinib Escalated Dosing in MF. Characteristics of Patients With MF and Ruxolitinib Resistance. - PowerPoint PPT PresentationTRANSCRIPT
Pivotal Data on Myeloid Disorders From the 2013 Hematology
Conference
Activity Goals
Myelofibrosis
Newly Identified Biological Pathway May Aid Diagnosis, Treatment of MPNs
Ruxolitinib Escalated Dosing in MF
Characteristics of Patients With MF and Ruxolitinib Resistance
Ruxolitinib Continues to Show Improved Survival in MF
Momelotinib for MF: Long-term Results
BMS-911543 in MF: Phase 1/2a Data
Fedratinib in Patients With Previous Ruxolitinib
Telomerase Inhibitor Imetelstat in MF
Myeloproliferative Neoplasms
Bone Marrow Features May Identify Early Polycythemia Vera
(PV)
History of Thrombosis at Diagnosis of ET
Splanchnic Vein Thrombosis and MPNs
LY2784544 for MF, PV, and ET
AOP2014 for PV: Phase 1/2 Study
AOP2014 for PV: Molecular Responses and Chromosomal Aberrations
Chronic Myeloid Leukemia
ENESTnd Trial Update: Nilotinib (NIL) vs Imatinib (IM)
First Results of the LASOR Trial: Switching From IM to NIL
STIM1 Study Long-term Follow-up
STIM2 Study: Preliminary Results
Immune Surveillance May Contribute to CML Control After TKI Discontinuation
Myelodysplastic Syndromes
Gene Mutation/Deletion Status Predicts Prognosis in
Myelodysplastic Syndromes (MDSs)
IPSS-R Predicts Response to Demethylating Agents (DMAs) in
MDS
IPSS-R Predicts Response to Erythropoietin-Stimulating Agents
(ESAs)
Response to Lenalidomide in Lower-risk MDS Better When Used as First-line Treatment
Combination of Vorinostat + Azacitidine in MDS
Genomic Changes Associated With Smoking
Epoetin Alpha (EPO) Effective in Low-risk MDS
Acute Lymphoblastic Leukemia
CTL019 Cells Efficacious in Pilot Study in Relapsed/Refractory ALL
CTL019 Cells Efficacious for Children With ALL Even After
Allogeneic Stem Cell Transplant (SCT)
Blinatumomab for Children With ALL
Inotuzumab Plus Mini-hyper-CVD for Older Adults With ALL
Pediatric Regimen for Adolescents and Young Adults With ALL: Toxicity Results
Pediatric Regimens for Adolescents and Young Adults With ALL
Acute Myeloid Leukemia
Explanations for Progress in Survival in Core Binding Factor
AML
Dasatinib for Newly Diagnosed AML
Sequential HAM Reduces Hematologic Toxicities in AML
Clofarabine Salvage Therapy May Be Bridge to SCT in AML
Selinexor (KPT-330) for AML: Phase 1 Data
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