- Plasters are solid or semisolid masses adhere to the skin when spread upon cotton felt line or muslin as a backing material and they are mainly used to,

A- Afford protection and mechanical support. B- Furnish an occlusive and macerating action. C- Bring medication into close contact with the

surface of the skin.

Plasters 

Parts of plasters

•Protective liner•Drug containing layer•Backing layer

adhesive plasters medicated plasters are used for local or

regional drug delivery transdermal delivery (or therapeutic)

systems (TTS) are used for long-term systemic delivery of therapeutic agents through the skin.

Examples: Nitroderm TTS, Estraderm TTS, Durogesic, etc.

Types of plaster

Also called a sticking plaster  Is a small dressing used for injuries not

serious enough to require a full-size bandage.

Adhesive plasters

The adhesive bandage protects the cut from friction, bacteria, damage, or dirt.

Thus, the healing process of the body is less disturbed.

Sometimes they have antiseptic properties. An additional function is to hold the two cut

ends of the skin together to make the healing process faster.

Function

An adhesive bandage is usually covered by woven fabric, plastic, or latex rubber which has an adhesive.

Adhesive bandages usually have an absorbent pad, which is sometimes medicated with an antiseptic solution.

Material

Some bandages have a thin, porous-polymer coating over the pad to keep it from sticking to the wound.

The bandage is applied such that the pad covers the wound, and the fabric or plastic sticks to the surrounding skin to hold the dressing in place and prevent dirt from entering the wound.

Band-Aid Curad Elastoplast Nexcare

Notable brands

Versatis medicated plasters  Versatis medicated plasters contain the

active ingredient lidocaine.

Medicated plasters

Main use Active ingredient Manufacturer

Nerve pain following shingles Lidocaine Grunenthal

Use with caution in Severely decreased liver function. Severely decreased kidney function. Severe heart problems. People taking medicines to treat an irregular

heart beat, for example mexiletine. People using other local anaesthetics.

Contents:  TTS 5 Patches: The average amount of

active substance nitroglycerine releases per application in 24 hrs is 5mg (Per hour releases 0.2mg).

TTS 10 Patches: The average amount of active substance nitroglycerine releases per application in 24 hours is 10mg (Per hour releases 0.4mg). 

Nitroderm TTS

Drug Classification: Glyceryl Trinitrate Patch

Trade Name Manufacturer(s):Novartis

Estraderm TTS patches contain the active ingredient estradiol ,which is a naturally occuring form of the main female sex hormone, oestrogen.

Estraderm TTS

Main use Active ingredient Manufacturer

Symptoms of the menopause

Estradiol Novartis

Used for Hormone replacement therapy to relieve

symptoms of the menopause. Second-line option for

preventing osteoporosis in postmenopausal women who are at high risk of fractures and cannot take other medicines licensed for preventing osteoporosis (Estraderm TTS 50 only).

Use with caution in Decreased kidney function. Heart failure. History of diabetes. History of gallstones. History of migraines or severe headaches. History of epilepsy. History of asthma.

Side effects Breakthrough bleeding and spotting. Breast pain, tenderness or enlargement. Headache/migraine. Redness or itching at patch application site. Leg cramps. Fatigue. Weight changes. Vaginal thrush. Depression. Anxiety. Dizziness.

Duragesic (fentanyl) is an opioid analgesic that is used for patients with chronic pain that is persistent, not managed by other opioids or non-steroidal analgesics, and are opioid-tolerant.

Duragesic

USES DURAGESIC is a transdermal formulation of

fentanyl indicated for the management of persistent, moderate to severe chronic pain in opioid-tolerant patients 2 years of age and older when a continuous.

SIDE-EFFECTS  Nausea, vomiting, dry mouth, constipation, hypotension and hypertension, bradycardia, somnolence, confusion, hallucinations, euphoria, pruritus, sweating and urinary retention.

www.netdoctor.co.uk www.pakmedinet.com Remington: The Science and Practice of

Pharmacy 21st edition pages no 948,1029,2309.

REFERENCES