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The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission. From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

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Page 1: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

Page 2: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

Page 3: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

Page 4: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

Page 5: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

Page 6: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.

Page 7: The New England Journal of Medicine Downloaded from nejm ...hedrick.ucsd.edu/BICD136/PDF-links/Gottlieb-NEJM-1981.pdfDownloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September

The New England Journal of Medicine Downloaded from nejm.org at UC SHARED JOURNAL COLLECTION on September 24, 2013. For personal use only. No other uses without permission.

From the NEJM Archive. Copyright © 2010 Massachusetts Medical Society. All rights reserved.