www.endo-aid.com

THE BEST VIEW YOU CAN GET

Clinical Evaluation of the EndoRings: “The CLEVER study”Final results of prospective, randomized, multi-center tandem colonoscopy trial

Drs. Peter Siersema, Doug Rex, Ian Gralnek, Ori Segol, Vincent Dik, Alain Suissa and Leon Moons performed a randomized, prospective tandem study comparing the EndoRings to standard colonoscopy in the Netherlands, United States and Israel.

in 126 patients, the Adenoma Detection Rate was 49.1% with the EndoRings, versus 28.8% with a standard colonoscope. The number of polyps and adenomas detected by the EndoRings was more than twice that of standard colonoscopy.

Standrad Colonoscopy EndoRings Colonoscopy59 patients35 patients

Out of:First pass Zero findings:

Second pass with EndoRings:

57 patients18 patients

13 patients (from 35) had a hyperplastic polyp/adenoma

detected with EndoRings Colonoscopy (37%)

0 patients (from 18) had a hyperplastic polyp/adenoma

detected with Standard Colonoscopy

ZERO DETECTION FAILURE

57 patients

18 patientszero find

59 patients

35 patientszero find

Standard Colonoscopy

EndoRings Colonoscopy

13 patientswith polyps

or adenomas

Polyps detected

0 20 40 60 80 100 120 140 160 180

61

166

Adenomas detected

0 20 40 60 80 100 120 140 160 180

3788

© 2016 EndoAid

EndoRingsTM II Distal Attachment

The EndoRings™ device features…

3 layers of flexible, soft circular rings – gently flatten folds during withdrawal for improved visibility.

Up to 50mm diameter – provides scope centering and stability of the endoscope during withdrawal and endoscopic therapy.

Drs. Peter Siersema, Doug Rex, Ian Gralnek, Ori Segol, Vincent Dik, Alain Suissa, and Leon Moons performed a randomized, prospective tandem study comparing the EndoRings to standard colonoscopy in the Netherlands, the United States, and Israel.In 126 patients, the Adenoma Detection Rate was 51% with the EndoRings versus 29% with a standard colonoscope. The number of polyps and adenomas detected by the EndoRings was more than twice that of standard colonoscopy.

Gentle smoothing of colon folds allows for improved visibility!

The EndoRings™ device easily attaches to the distal end of adult and slim colonoscopes to provide:

Scope centering during screening

Anchoring duringendoscopic therapy

Improved visibility

Adenomas detectedPolyps detected

180

160

140

120

100

80

60

40

20

0

166

61

90

37

EndoRings™Standard scope

It's in the Rings

www.endo-aid.com

Gentle smoothing of colon folds allows for improved visibility

EndoRings II Distal Attachment

• Do you send all your patients home, polyp-free?

• How well can you see behind the colon’s folds?

• How can you better find hidden polyps with your preferred colonoscope and workflow?

37% of the zero detected polyp/adenoma patients undergoing standard colonocopy are misdiagnosed

FEATURES BENEFITS

Up to 50mm diameter

● Gently flattens colon folds during withdrawal for improved view

Unique design -

2 layers of rings

● Maintains a central position in the lumen

● Stabilizes scope during polypectomy

● Minimal resistance during insertion

Soft silicone material

● Collapses during insertion

● Enables easy ilial intubation

● Latex Free

2 sizes● E102 - Adult Colonoscope Fit

● E103 - Slim Adult Colonoscope Fit

EndoRings II is a silicone-rubber device that is fitted onto the distal end of the colonoscope. 2 layers of flexible, soft circular rings, gently flatten folds during withdrawal for improved visibility. Colonoscopy with the EndoRings II does not interfere with the normal washing, suctioning, and therapeutic capabilities of the colonoscope and does not interfere with the field of view.

The EndoRings™ device features…

3 layers of flexible, soft circular rings – gently flatten folds during withdrawal for improved visibility.

Up to 50mm diameter – provides scope centering and stability of the endoscope during withdrawal and endoscopic therapy.

Drs. Peter Siersema, Doug Rex, Ian Gralnek, Ori Segol, Vincent Dik, Alain Suissa, and Leon Moons performed a randomized, prospective tandem study comparing the EndoRings to standard colonoscopy in the Netherlands, the United States, and Israel.In 126 patients, the Adenoma Detection Rate was 51% with the EndoRings versus 29% with a standard colonoscope. The number of polyps and adenomas detected by the EndoRings was more than twice that of standard colonoscopy.

Gentle smoothing of colon folds allows for improved visibility!

The EndoRings™ device easily attaches to the distal end of adult and slim colonoscopes to provide:

Scope centering during screening

Anchoring duringendoscopic therapy

Improved visibility

Adenomas detectedPolyps detected

180

160

140

120

100

80

60

40

20

0

166

61

90

37

EndoRings™Standard scope

It's in the Rings

www.endo-aid.com

For each 1% increase in adenoma detection rate (ADR) there is a 3% reduction in the risk of interval colorectal cancer(Douglas Corley, MD, from Kaiser Permanente in Oakland , California)

THE BEST VIEW YOU CAN GET