anatomical terms outline
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Anatomy - The Study of Form
Examining structure of the Human Body inspection
palpation
auscultation
percussion
Cadaver dissection cutting and separation of tissues to reveal their
relationships
Comparative anatomy study of more than one species in order to examine
structural similarities and differences, and analyze
evolutionary trends
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Exploratory Surgery
open body and take a look inside
Medical imaging viewing the inside of the body without surgery
Radiologybranch of medicine concerned with imaging
Gross Anatomy study of structures that can be seen with the naked eye
Cytology study of structure and function of cells
Histology (microscopic anatomy) examination of cells with microscope
Ultrastructure the molecular detail seen in electron microscope
Histopathology
microscopic examination of tissues for signs of disease
Anatomy - The Study of Form
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Physiology - The Study ofFunction
Subdisciplines
neurophysiology (physiology of nervous system)
endocrinology (physiology of hormones)
pathophysiology (mechanisms of disease)
Comparative Physiology
limitations on human experimentation
study of different species to learn about bodily function animal surgery
animal drug tests
basis for the development of new drugs and medical
procedures
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Hierarchy of Complexity Organism a single, complete individual
Organ Systemhuman body made of 11 organ systems
Organstructure composed of two or more tissue types that work together to carryout a particular function
Tissuea mass of similar cells and cell products that form discrete region of anorgan and performs a specific function
Cells the smallest units of an organism that carry out all the basic functions of life Cytology the study of cells and organelles
Organelles
microscopic structures in a cell that carry out its individual functions
Moleculesmake up organelles and other cellular components
macromolecules proteins, carbohydrates, fats, DNA
Atomsthe smallest particles with unique chemical identities1-4
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Characteristics of Life Organization
Cellular composition
Metabolism
anabolism, catabolism and excretion
Responsiveness and movement
stimuli
Homeostasis
Development
differentiation and growth
Reproduction
Evolution
mutations
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Physiological Variation
Sex, age, diet, weight, physical activity
Typical physiological values
reference man 22 years old, 154 lbs, light physical activity
consumes 2800 kcal/day
reference woman
same as man except 128 lbs and 2000 kcal/day
Overmedication of elderly
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Homeostasis Homeostasisthe bodys ability to detect change,
activate mechanisms that oppose it, and thereby maintainrelatively stable internal conditions
Claude Bernard (1813-78) constant internal conditions regardless of external
conditions internal body temperature ranges from 97 to 99 degrees despitevariations in external temperature
Walter Cannon (1871-1945) coined the term Homeostasis
state of the body fluctuates (dynamic equilibrium) withinlimited range around a set point
Negative feedback keeps variable close to the set point
Loss of homeostatic control causes illness
or death
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Negative Feedback in HumanThermoregulation
Brain senses change in blood temperature
if to warm, vessels dilate (vasodilation) in the skin and sweatingbegins (heat losing mechanisms)
if too cold, vessels in the skin constrict (vasoconstriction)and shivering begins (heat gaining mechanism)
Time
Sweating
Set point
Vasoconstriction
Vasodilation
36.5C
(97.7F)
37.0C
(98.6F)
37.5C(99.5F)
Shivering
Corebodytemperature
Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Figure 1.10
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Negative Feedback Control ofBlood Pressure
Sitting up in bed causes a drop in blood pressurein the head and upper thorax
Baroreceptors in the arteries near the heart alert
the cardiac center in the brainstem
Cardiac center sends nerve signals that increasethe heart rate and return the blood pressure to
normal Failure of this to feedback loop may produce
dizziness in the elderly
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3 Components of a FeedbackLoop
Receptor - senses change in the body
Integrating (Control) Center - controlcenter that processes the sensoryinformation, makes a decision, anddirects the response
Effectorcarries out the final correctiveaction to restore homeostasis
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Positive Feedback Loops Self-amplifying cycle
leads to greater change in the same direction feedback loop is repeated change produces more change
Normal way of producing rapid changes occurs with childbirth, blood clotting, protein digestion, fever, and
generation of nerve signals
Head of fetus
pushes against cervix
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3
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Oxytocin stimulates uterine
contractions and pushes
fetus toward cervix
Nerve impulses
from cervix
Transmitted
to brain
Brain stimulates
pituitary gland to
secrete oxytocin
Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Figure 1.12
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Harmful Positive Feedback Loop
Fever > 104 degrees F
metabolic rate increases
body produces heat even faster
body temperature continues to rise
further increasing metabolic rate
Cycle continues to reinforce itself
Becomes fatal at 113 degrees F
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Importance of Precision
Be precise in your terms
Spell correctly
Health Care professions demand thesame type of precision
Peoples lives will be in your hands
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Review of Major Themes
Cell Theory All structure and function result from the activity of cells
Homeostasis The purpose of most normal physiology is to maintain stable
conditions within the body
Evolution The human body is a product of evolution
Hierarchy of Structure Human structure can be viewed as a series of levels of complexity
Unity of Form and Function Form and function complement each other; physiology cannot be
divorced from anatomy
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Medical Imaging
Radiography (x rays)
William Roentgen - 1885
penetrate tissues to
darken photographic filmbeneath the body
dense tissue appearswhite
over half of all medicalimaging
until 1960s, it was the only
method widely available
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Medical Imaging
Radiopaque substances
injected or swallowed
fills hollow structures
blood vessels
intestinal tract
(b) Cerebral angiogramCustom Medical Stock Photo, Inc.
Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Figure 1.13b
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Medical Imaging
ComputedTomography (CTscan)
formerly called a CATscan
low-intensity X raysand computer analysis
slice type image increased
sharpness of image
Figure 1.13c
(c) Computed tomographic (CT) scan
CNR/Phototake
Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
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Medical Imaging - Nuclear Medicine
Positron Emission Tomography (PET scan)
assesses metabolic state of tissue
distinguished tissues most active at a
given moment mechanics
inject radioactively labeled glucose
positrons and electrons collide
gamma rays given off detected by sensor
analyzed by computer
image color shows which tissues
were using the most glucose at that moment
damaged tissues appear dark
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Medical Imaging
Magnetic ResonanceImaging (MRI)
slice type image
superior quality to CT scan
best for soft tissue
mechanics
alignment & realignment ofhydrogen atoms withmagnetic field & radio waves
varying levels of energygiven off used by computerto produce an image
(e) Magnetic resonance image (MRI)
Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction or display.
Monte S. Buchsbaum, Mt. Sinai School of Medicine, New York, NY
Figure 1.13e